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The bone cancer treatment market was valued at USD 1.08 Billion in 2025 and is expected to grow at a CAGR of 4.50%, reaching USD 1.68 Billion by 2035. The market growth is driven by the growing prevalence of bone tumors and increasing adoption of targeted therapy drugs across the 8 major markets. It is further driven by the increasing adoption of minimally invasive surgical procedures and rising awareness of musculoskeletal health. Advancements in implant materials and expanded healthcare access are expected to support market growth.
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In August 2023, City of Hope became the first in Southern California to offer SCINTIX™ biology-guided radiotherapy for metastatic bone cancer, significantly enhancing precision care, expected to drive market growth through advanced radiotherapy adoption.
Strategic acquisitions to strengthen bone cancer pipelines is one of the major market trends. For instance, in May 2024, Telix acquired QSAM Biosciences, adding 153Sm-DOTMP, a targeted radiopharmaceutical for metastatic bone cancer treatment and pain relief.
Rising incidence of bone cancer and advancements in targeted therapies are significantly boosting the bone cancer treatment market across major regions. Key players' focus on R&D and novel drug approvals continues to drive market expansion.
Bone cancer treatment involves a multidisciplinary approach that includes surgery, chemotherapy, radiation therapy, and targeted therapies aimed at eliminating cancerous cells and preserving bone function. Advancements in diagnostic imaging and precision medicine have significantly enhanced treatment outcomes and patient quality of life. The market is poised to grow at a CAGR of 4.50% during the forecast period of 2026–2035. It is driven by increasing cancer prevalence, rising awareness, and technological progress in oncology care across major regions. The growing healthcare investments and the development of novel therapeutics further support market expansion.
Rising Bone Cancer Prevalence to Drive Growth in the Market
The increasing incidence of bone cancer remains a primary driver of market expansion across the 8 major markets. A notable rise in newly diagnosed cases highlights growing demand for advanced therapeutic options. In India, according to a March 2024 report by the Indian Cancer Society, approximately 4,000 new bone cancer cases are reported annually. Although bone cancer represents only about 5% of total cancer cases globally, the burden it imposes is significant. This trend in diagnosis continues to fuel innovation and investment, supporting consistent growth in the bone cancer treatment market.
The market is experiencing several emerging trends, including the expansion of biosimilar approvals and the development of innovative biomaterials.
Expansion of Biosimilar Approvals Expected to Boost the Market Value
The market is witnessing a notable trend of biosimilar integration, enhancing treatment accessibility and cost-efficiency. In July 2025, the European Commission granted marketing authorization to Biocon Biologics’ Denosumab biosimilars, Vevzuo® and Evfraxy®, for its use in various bone-related conditions, including giant cell tumor of bone and cancer-related bone complications. This regulatory milestone highlights growing acceptance of biosimilars in oncology and orthopedics. The trend is expected to significantly drive market growth through broader therapeutic options and improved patient access.
Innovative Biomaterials Driving Advancements in Bone Cancer Therapies Likely to Boost Bone Cancer Treatment Market
The development of advanced biomaterials that combine therapeutic and regenerative functions is a rising trend in the market. In February 2025, researchers at Aston University and the Royal Orthopaedic Hospital initiated a collaborative project to develop an injectable gallium-doped bioglass paste. This novel material is designed to eliminate residual cancer cells while promoting bone regeneration and minimizing infection risks. Such innovations represent a transformative approach in bone oncology, likely to accelerate market growth through improved treatment outcomes and reduced recurrence rates.
Intravenous Administration Expected to Lead the Market Share by Route of Administration
The market segmentation based on the route of administration includes oral and intravenous. Each method offers unique advantages in terms of drug delivery, patient compliance, and treatment efficacy. However, intravenous administration is expected to lead the market due to its widespread use in delivering complex biologics and immunotherapies such as Dinutuximab Beta. Dinutuximab Beta, administered intravenously, has shown promising results in treating high-risk neuroblastoma and various bone cancers, including osteosarcoma and Ewing sarcoma. Its targeted mechanism and controlled infusion schedule enhance therapeutic precision, making IV administration a preferred route in clinical oncology settings. The ability to deliver monoclonal antibodies and combination regimens effectively via infusion further solidifies intravenous administration's leadership in the market.
The market is divided into regions such as the United States, the United Kingdom, Germany, France, Italy, Spain, Japan, and India. Among these, the United States is expected to lead due to its advanced healthcare infrastructure, significant research investments, and rising incidence of bone cancer. According to Cancer Therapy Advisor, approximately 1,000 cases of osteosarcoma are diagnosed annually in the United States, with around 50% occurring in children, adolescents, and young adults, and 10% in individuals aged 60 years and older.
The bone cancer treatment market research report by Expert Market Research provides an in-depth analysis of the competitive landscape, offering key insights into patent filings, grant analysis, funding trends, investments, and strategic initiatives by major players. It tracks recent investments, mergers, acquisitions, and partnerships that showcase the market's growth trajectory. Additionally, the report details strategic activities by leading companies, including regional expansions, adoption of new technologies, and efforts to enhance capacity, helping stakeholders better understand the market dynamics and positions of key industry players. Some of the leading players are as follows:
Amgen Inc. plays a pivotal role in the bone cancer treatment market through its innovative therapy, XGEVA™ (denosumab). Approved by the U.S. Food and Drug Administration, XGEVA is the first and only RANK Ligand inhibitor indicated for the prevention of skeletal-related events in patients with bone metastases from solid tumors. Its approval, backed by extensive Phase 3 clinical trials, marks a significant advancement in reducing debilitating bone complications in cancer patients.
Hikma Pharmaceuticals, a global provider of high-quality medicines, expanded its oncology portfolio with the launch of Adriamycin™ (Doxorubicin HCl) for Injection in the United States. This anthracycline topoisomerase II inhibitor is indicated for several cancers, including metastatic bone sarcomas. Through this product, Hikma strengthens its position in the Bone Cancer Treatment Market, supporting access to essential chemotherapy options.
Johnson & Johnson Pharmaceuticals Inc. is a leading healthcare company actively involved in oncology research and treatment development. The company advanced its presence in bone-related cancer therapies with the U.S. FDA approval of Tecvayli (teclistamab), a bispecific antibody for multiple myeloma, a blood cancer that originates in the bone marrow. Tecvayli targets hard-to-treat or relapsed cases, offering a novel option in addressing this aggressive bone-associated malignancy.
Zetagen is a biotechnology company focused on addressing metastatic cancer lesions, particularly in bone. It has developed ZetaMet™ (Zeta-BC-003), a synthetic small molecule aimed at resolving bone lesions, relieving pain, and regenerating bone. Awarded Breakthrough Designation by the U.S. FDA, ZetaMet™ is undergoing clinical trials in Canada for metastatic breast cancer lesions. Zetagen's innovations represent a promising shift in bone cancer treatment strategies.
*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*
Other key players in the market include Bayer AG, Novartis AG, Spectrum Pharmaceuticals Inc., Eli Lilly and Company, Pfizer Inc., and Takeda Pharmaceutical Company.
The market report offers a detailed analysis of the market based on the following segments:
Market Breakup by Type
Market Breakup by Treatment Type
Market Breakup by Route of Administration
Market Breakup by End User
Market Breakup by Region
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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| REPORT FEATURES | DETAILS |
| Base Year | 2025 |
| Historical Period | 2019-2025 |
| Forecast Period | 2026-2035 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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| Breakup by Type |
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| Breakup by Treatment Type |
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| Breakup by Route of Administration |
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| Breakup by End User |
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| Breakup by Region |
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