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Protein Crystallization Market

Global Protein Crystallization Market Size, Analysis, Report: By Product: Instruments, Consumables, Software and Services; By Technology: X-ray Crystallography, Cryo-electron Microscopy, NMR Spectroscopy, Others; By End User: Pharmaceutical Companies, Biotechnology Companies, Others; Regional Analysis; Supplier Landscape; 2024-2032

Global Protein Crystallization Market Outlook

The global protein crystallization market size was valued at USD 1.41 billion in 2023, driven by the increasing demand and development on protein therapeutics across the globe. The market is expected to grow at a CAGR of 8.5% during the forecast period of 2024-2032, with the values likely to rise from USD 1.53 billion in 2024 to USD 2.94 billion by 2032.

 

Protein Crystallization: Introduction

Protein crystallization is the process of creating a structured and ordered lattice for a complex form of protein, inhibiting molecule denaturation. It is used in medicinal biochemistry and structural biology for drug development along with formulation, separation, and purification of protein therapeutics. Protein crystallization is a brilliant alternative to chromatography and other purification methods as it helps in creating pure and contamination free protein.

 

Protein crystallization is dependent on a specific pH, temperature, and chemical additives. It is applied in a variety of methods, including X-Ray crystallography, cryogenic electron microscopy, NMR spectroscopy, small-angle X-ray scattering, as well as neutron diffraction.

 

Global Protein Crystallization Market Analysis

With the COVID-19 outbreak, research in protein therapeutics, drug discovery and design has experienced a sudden growth. The development and demand for innovation in protein crystallization techniques has also grown, since it is an essential element of protein therapeutics and drug development. Protein based therapeutics are projected to take half space in the list of top ten most selling drugs in 2024 . This indicates protein crystallization market growth in the future as well.

 

There has been some significant research in the protein crystallization domain to bring accurate, economical and rapid results. MIT engineers  have invented a new approach that uses specialized nanoparticles to crystallize the protein fast and at much cheaper prices. According to their findings, bioconjugate-coated nanoparticles accelerated protein crystallization process, reducing the induction time by seven folds. As we progress into the future, we can expect more significant and relevant improvements in the market.

 

Governments and research organisations are heavily investing in protein crystallization market research as it is relevant in multiple techniques like cryo-electron microscopy, NMR spectroscopy and others. So, with any development in these techniques, we can expect a growth in the protein crystallization market as well.

 

Global Protein Crystallization Market Segmentation

Market Breakup by Product

  • Instruments
  • Consumables
  • Software and Services

 

Market Breakup by Technology

  • X-ray Crystallography
  • Cryo-electron Microscopy 
  • NMR Spectroscopy 
  • Others

 

Market Breakup by End User

  • Pharmaceutical Companies
  • Biotechnology Companies
  • Government Institutes
  • Academic Institutions
  • Others

 

Market Breakup by Region

  • North America
  • Europe
  • Asia Pacific 
  • Latin America
  • Middle East and Africa

Global Protein Crystallization Market Overview

The North American region has led the global market share for protein crystallization. This can be attributed to the extensive investments in research and development by both government and healthcare corporations. The presence of key innovators in the area has propelled significant growth in the market.

 

The protein crystallization market demand is anticipated to peak in the Asia Pacific region during the forecast period, with increasing investments and research in the healthcare and biotechnological industry. For instance, Tokyo Institute of Technology has recently developed a new cell-free protein crystallization (CFPC) method. This enables the study of unstable and low-yield proteins that could not be studied with the help of usual methods. This opens a new spectrum of further development and growth in the field, indicating possible development in the Asia Pacific region.

 

Global Protein Crystallization Market: Competitor Landscape

The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:

 

  • Bruker 
  • HAMPTON RESEARCH CORP. 
  • Rigaku Corporation 
  • Mettler Toledo 
  • Corning Incorporated 
  • Jena Bioscience Gmbh 
  • Creative Proteomics 
  • Formulatrix 
  • Molecular Dimensions 
  • Greiner Bio-One International Gmbh 
  • SARomics Biostructures AB

 

Key Highlights of the Report

REPORT FEATURES DETAILS
Base Year 2023
Historical Period 2017-2023
Forecast Period 2024-2032
Scope of the Report

Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:

  • Product
  • Technology
  • End User
  • Region
Breakup by Product
  • Instruments
  • Consumables
  • Software and Services
Breakup by Technology
  •  X-ray Crystallography
  • Cryo-electron Microscopy
  • NMR Spectroscopy
  • Others
Breakup by End User
  • Pharmaceutical Companies
  • Biotechnology Companies
  • Government Institutes
  • Academic Institutions
  • Others
Breakup by Region
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa
Market Dynamics
  • Market Drivers and Constraints
  • SWOT Analysis
  • Porter’s Five Forces Model 
  • Key Demand Indicators
  • Key Price Indicators
  • Industry Events, Initiatives, and Trends 
  • Value Chain Analysis
Competitive Landscape
  • Market Structure
  • Company Profiles
    • Financial Analysis
    • Product Portfolio
    • Demographic Reach and Achievements
    • Mergers and Acquisitions
    • Certifications
Companies Covered
  • Bruker
  • HAMPTON RESEARCH CORP.
  • Rigaku Corporation
  • Mettler Toledo
  • Corning Incorporated
  • Jena Bioscience Gmbh
  • Creative Proteomics
  • Formulatrix
  • Molecular Dimensions
  • Greiner Bio-One International Gmbh
  • SARomics Biostructures AB

 

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.

1    Preface
    1.1    Objectives of the Study
    1.2    Key Assumptions 
    1.3    Report Coverage – Key Segmentation and Scope  
    1.4    Research Methodology
2    Executive Summary
3    Global Protein Crystallization Market Overview 

    3.1    Global Protein Crystallization Market Historical Value (2017-2023) 
    3.2    Global Protein Crystallization Market Forecast Value (2024-2032)
4    Global Protein Crystallization Market Landscape
    4.1    Global Protein Crystallization Developers Landscape
        4.1.1    Analysis by Year of Establishment
        4.1.2    Analysis by Company Size
        4.1.3    Analysis by Region
    4.2    Global Protein Crystallization Product Landscape
        4.2.1    Analysis by Product
        4.2.2    Analysis by Technology
5    Global Protein Crystallization Market Dynamics
    5.1    Market Drivers and Constraints
    5.2    SWOT Analysis
    5.3    Porter’s Five Forces Model 
    5.4    Key Demand Indicators
    5.5    Key Price Indicators
    5.6    Industry Events, Initiatives, and Trends 
    5.7    Value Chain Analysis
6    Global Protein Crystallization Market Segmentation 
    6.1    Global Protein Crystallization Market by Product
        6.1.1    Market Overview                   
        6.1.2    Instruments
        6.1.3    Consumables
        6.1.4    Software and Services
    6.2    Global Protein Crystallization Market by Technology
        6.2.1    Market Overview
        6.2.2    X-ray Crystallography
        6.2.3    Cryo-electron Microscopy
        6.2.4    NMR Spectroscopy
        6.2.5    Others
    6.3    Global Protein Crystallization Market by End User
        6.3.1    Market Overview
        6.3.2    Pharmaceutical Companies 
        6.3.3    Biotechnology Companies 
        6.3.4    Government Institutes 
        6.3.5    Academic Institutions
        6.3.6    Others
    6.4    Global Protein Crystallization Market by Region
        6.4.1    Market Overview
        6.4.2    North America 
        6.4.3    Europe
        6.4.4    Asia Pacific
        6.4.5    Latin America
        6.4.6    Middle East and Africa
7    North America Protein Crystallization Market
    7.1    Market Share by Country
    7.2    United States of America
    7.3    Canada
8    Europe Protein Crystallization Market
    8.1    Market Share by Country
    8.2    United Kingdom
    8.3    Germany
    8.4    France
    8.5    Italy
    8.6    Others
9    Asia Pacific Protein Crystallization Market
    9.1    Market Share by Country
    9.2    China
    9.3    Japan
    9.4    India
    9.5    ASEAN
    9.6    Australia
    9.7    Others
10    Latin America Protein Crystallization Market
    10.1    Market Share by Country
    10.2    Brazil
    10.3    Argentina
    10.4    Mexico
    10.5    Others
11    Middle East and Africa Protein Crystallization Market
    11.1    Market Share by Country
    11.2    Saudi Arabia
    11.3    United Arab Emirates
    11.4    Nigeria
    11.5    South Africa
    11.6    Others
12    Patent Analysis
    12.1    Analysis by Type of Patent
    12.2    Analysis by Publication year
    12.3    Analysis by Issuing Authority
    12.4    Analysis by Patent Age
    12.5    Analysis by CPC Analysis
    12.6    Analysis by Patent Valuation 
    12.7    Analysis by Key Players
13    Grants Analysis
    13.1    Analysis by year
    13.2    Analysis by Amount Awarded
    13.3    Analysis by Issuing Authority
    13.4    Analysis by Grant Application
    13.5    Analysis by Funding Institute
    13.6    Analysis by NIH Departments
    13.7    Analysis by Recipient Organization
14    Funding Analysis
    14.1    Analysis by Funding Instances
    14.2    Analysis by Type of Funding
    14.3    Analysis by Funding Amount
    14.4    Analysis by Leading Players
    14.5    Analysis by Leading Investors
    14.6    Analysis by Geography
15    Partnership and Collaborations Analysis
    15.1    Analysis by Partnership Instances
    15.2    Analysis by Type of Partnership
    15.3    Analysis by Leading Players
    15.4    Analysis by Geography
16    Regulatory Framework
    16.1    Regulatory Overview
        16.1.1    US FDA
        16.1.2    EU EMA
        16.1.3    INDIA CDSCO
        16.1.4    JAPAN PMDA
        16.1.5    Others
17    Supplier Landscape
    17.1    Bruker
        17.1.1    Financial Analysis
        17.1.2    Product Portfolio
        17.1.3    Demographic Reach and Achievements
        17.1.4    Mergers and Acquisitions
        17.1.5    Certifications
    17.2    HAMPTON RESEARCH CORP.
        17.2.1    Financial Analysis
        17.2.2    Product Portfolio
        17.2.3    Demographic Reach and Achievements
        17.2.4    Mergers and Acquisitions
        17.2.5    Certifications
    17.3    Rigaku Corporation
        17.3.1    Financial Analysis
        17.3.2    Product Portfolio
        17.3.3    Demographic Reach and Achievements
        17.3.4    Mergers and Acquisitions
        17.3.5    Certifications
    17.4    Mettler Toledo
        17.4.1    Financial Analysis
        17.4.2    Financial Portfolio
        17.4.3    Demographic Reach and Achievements
        17.4.4    Mergers and Acquisitions
        17.4.5    Certifications
    17.5    Corning Incorporated
        17.5.1    Financial Analysis
        17.5.2    Product Portfolio
        17.5.3    Demographic Reach and Achievements
        17.5.4    Mergers and Acquisitions
        17.5.5    Certifications
    17.6    Jena Bioscience Gmbh
        17.6.1    Financial Analysis
        17.6.2    Product Portfolio
        17.6.3    Demographic Reach and Achievements
        17.6.4    Mergers and Acquisitions
        17.6.5    Certifications
    17.7    Creative Proteomics
        17.7.1    Financial Analysis
        17.7.2    Product Portfolio
        17.7.3    Demographic Reach and Achievements
        17.7.4    Mergers and Acquisitions
        17.7.5    Certifications
    17.8    Formulatrix
        17.8.1    Financial Analysis
        17.8.2    Product Portfolio
        17.8.3    Demographic Reach and Achievements
        17.8.4    Mergers and Acquisitions
        17.8.5    Certifications
    17.9    Molecular Dimensions
        17.9.1    Financial Analysis
        17.9.2    Product Portfolio
        17.9.3    Demographic Reach and Achievements
        17.9.4    Mergers and Acquisitions
        17.9.5    Certifications
    17.10    Greiner Bio-One International Gmbh
        17.10.1    Financial Analysis
        17.10.2    Product Portfolio
        17.10.3    Demographic Reach and Achievements
        17.10.4    Mergers and Acquisitions
        17.10.5    Certifications
    17.11    SARomics Biostructures AB
        17.11.1    Financial Analysis
        17.11.2    Product Portfolio
        17.11.3    Demographic Reach and Achievements
        17.11.4    Mergers and Acquisitions
        17.11.5    Certifications
18    Global Protein Crystallization Market - Distribution Model (Additional Insight)
    18.1    Overview 
    18.2    Potential Distributors 
    18.3    Key Parameters for Distribution Partner Assessment 
19    Key Opinion Leaders (KOL) Insights (Additional Insight)
20    Company Competitiveness Analysis (Additional Insight)

    20.1    Very Small Companies
    20.2    Small Companies
    20.3    Mid-Sized Companies
    20.4    Large Companies
    20.5    Very Large Companies
21    Payment Methods (Additional Insight)
    21.1    Government Funded
    21.2    Private Insurance
    21.3    Out-of-Pocket


*Additional insights provided are customisable as per client requirements.

Key Questions Answered in the Report

The market attained a value of about USD 1.41 billion in 2023, driven by the rising emphasis and development in protein therapeutics across the globe.

The market is anticipated to grow at a CAGR of 8.5% during the forecast period of 2024-2032, likely to reach a market value of USD 2.94 billion by 2032.

Increased investment and demand in protein therapeutics, new drug designs and production, especially post COVID-19, are some of the major factors contributing to the rising demand.

Within the Asia Pacific region, the Asian countries are expected to see a high growth at the end of the forecast period, owing to high investments from government to develop infrastructure and introduce innovation.

Protein crystallization products include instruments, consumables, software, and services.

Major application areas include X-ray crystallography, cryo-electron microscopy, and NMR spectroscopy, among others.

The major regions of the market include North America, Europe, Asia Pacific, Latin America, Middle East, and Africa. North America is currently leading the global market.

The end users in the market include pharmaceutical companies, biotechnology companies, government institutes, academic institutions, and others.

Key players involved in the market are Bruker, HAMPTON RESEARCH CORP., Rigaku Corporation, Mettler Toledo, Corning Incorporated, Jena Bioscience Gmbh, Creative Proteomics, Formulatrix, Molecular Dimensions, Greiner Bio-One International Gmbh, and SARomics Biostructures AB.

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