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Cytokine release syndrome (CRS), also known as cytokine storm or cytokine-associated toxicity, is a severe clinical syndrome characterized by drastic elevation of inflammatory cytokines. This potentially life-threatening condition can be triggered by infections and certain types of immunotherapies. Various studies suggest that 43 to 100% of study patients affected by leukemia or lymphoma, who receive CAR-T cell therapy targeted to CD19, are affected by cytokine release syndrome.
Base Year
Historical Year
Forecast Year
Expert Market Research's “Cytokine Release Syndrome Epidemiology Forecast Report 2024-2032” offers comprehensive information on the prevalence and demographics of cytokine release syndrome. It projects the future incidence and prevalence rates of cytokine release syndrome across various populations. The study covers age and type as major determinants of the cytokine release syndrome-affected population. The report highlights patterns in the prevalence of cytokine release syndrome over time and projects future trends based on multiple variables.
The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of cytokine release syndrome in the 8 major markets.
Regions Covered
In cytokine release syndrome, an individual's immune system aggressively responds to immunotherapy drugs or infection due to the rapid release of a large amount of cytokines in the blood. Cytokine release syndrome is primarily linked to chimeric antigen receptor (CAR)-T cell therapy but is also observed to occur with bispecific T cell engager therapy and monoclonal antibody-based therapy. Cytokine storms can impact multiple organs, with the symptoms ranging from mild (flu-like symptoms) to severe (low blood pressure, high fever, difficulty in breathing, and multi-organ failure).
The treatment plan for this systemic inflammatory response depends on the grade of cytokine release syndrome. For Grade 2 CRS, moderate therapeutic interventions such as fluids or vasopressors for hypotension are sufficient to manage the symptoms. Grade 3 CRS needs aggressive intervention like high doses or multiple vasopressor drugs for hypotension. In Grade 4 CRS, immunosuppressants and mechanical ventilation are required.
The cytokine release syndrome epidemiology section offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for cytokine release syndrome by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for cytokine release syndrome and their trends. The data is broken down into specific categories, such as the total diagnosed cases across different age groups and patient pools.
The cytokine release syndrome epidemiology data and findings for the United States, EU-4 (Germany, Spain, Italy, France), the United Kingdom, Japan, and India are also provided in the epidemiology section.
The epidemiology of cytokine release syndrome varies significantly between countries due to several factors that influence its prevalence, diagnosis, and management. A higher incidence of this systemic inflammatory response is reported in countries with greater access to advanced treatments such as CAR T-cell therapies and other immunotherapeutic options. Moreover, regions with a higher burden of hematological malignancies also tend to observe more cases of cytokine release syndrome.
Country Specific Stats:
Country |
Prevalence (Unit) |
United States |
XX |
United Kingdom |
XX |
Germany |
XX |
Italy |
XX |
France |
XX |
Spain |
XX |
Japan |
XX |
India |
XX |
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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Report Features |
Details |
Base Year |
2023 |
Historical Period |
2017-2023 |
Forecast Period |
2024-2032 |
Geographies Covered |
|
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Australia
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+61 448 06 17 27
India
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+91-858-608-1494
Philippines
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+63 287899028, +63 967 048 3306
United Kingdom
6 Gardner Place, Becketts Close, Feltham TW14 0BX, Greater London
+44-753-713-2163
United States (Head Office)
30 North Gould Street, Sheridan, WY 82801
+1-415-325-5166
Vietnam
193/26/4 St.no.6, Ward Binh Hung Hoa, Binh Tan District, Ho Chi Minh City
+84865399124
United States (Head Office)
30 North Gould Street, Sheridan, WY 82801
+1-415-325-5166
Australia
63 Fiona Drive, Tamworth, NSW
+61 448 06 17 27
India
C130 Sector 2 Noida, Uttar Pradesh 201301
+91-858-608-1494
Philippines
40th Floor, PBCom Tower, 6795 Ayala Avenue Cor V.A Rufino St. Makati City, 1226.
+63 287899028, +63 967 048 3306
United Kingdom
6 Gardner Place, Becketts Close, Feltham TW14 0BX, Greater London
+44-753-713-2163
Vietnam
193/26/4 St.no.6, Ward Binh Hung Hoa, Binh Tan District, Ho Chi Minh City
+84865399124
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