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Report Overview

Functional dyspepsia remains a prevalent U.S. gastrointestinal disorder, affecting roughly 12% of adults. Its persistent clinical burden reinforces the need for enhanced awareness, timely diagnosis, and optimized patient-centered management strategies. The functional dyspepsia epidemiology forecast by Expert Market Research indicates that the condition can occur at any age but more common in young and middle-aged adults. It is more common in females than males (female-to-male ratio ≈ 1.5–2:1).

2025

Base Year

2019-2025

Historical Period

2026-2035

Forecast Period

Functional Dyspepsia – Number of Cases by Year

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Functional Dyspepsia Epidemiology Forecast Report Coverage

Expert Market Research's “Functional Dyspepsia Epidemiology Forecast Report 2026-2035” offers comprehensive information on the prevalence and demographics of functional dyspepsia. It projects the future incidence and prevalence rates of functional dyspepsia cases across various populations. The study covers age, gender, and type as major determinants of the functional dyspepsia population. The report highlights patterns in the prevalence of functional dyspepsia over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on functional dyspepsia epidemiology in the 8 major markets.

Regions Covered

  • The United States
  • Germany
  • France
  • Italy
  • Spain
  • The United Kingdom
  • Japan
  • India

Functional Dyspepsia Understanding: Disease Overview

Functional dyspepsia is a common chronic upper gastrointestinal disorder characterized by postprandial fullness, early satiety, and epigastric pain in the absence of structural abnormalities. Classified into postprandial distress syndrome and epigastric pain syndrome, functional dyspepsia arises from altered motility, visceral hypersensitivity, impaired gastric accommodation, and potential gut–brain axis dysfunction. Although not life-threatening, it significantly affects quality of life and healthcare utilization. Rising global prevalence highlights the need for more precise diagnostic criteria and targeted therapies, positioning FD as a growing focus within gastroenterology and digestive health research.

Functional Dyspepsia Epidemiology Perspective

The functional dyspepsia epidemiology division offers information on the patient pool from history to the present, as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for the functional dyspepsia epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for functional dyspepsia and their trends. The functional dyspepsia detailed epidemiology segmentation is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.

  • Functional gastrointestinal disorders affect ~40% of the global population, with functional dyspepsia showing a worldwide prevalence of 5-11%, and even higher (10-40%) in Western countries.
  • Epidemiological studies indicate a wider range (8–23%), with particularly high prevalence in East and Southeast Asia, possibly linked to dietary patterns, Helicobacter pylori prevalence, and psychosocial stress.
  • Functional dyspepsia is notably more common in women than men, driven by sex-specific hormonal mechanisms, pain-signaling differences, and healthcare-seeking patterns.
  • The prevalence tends to decline slightly with advancing age, possibly because older adults with dyspeptic symptoms are more likely to have organic diseases such as peptic ulcers, malignancies, or biliary disorders.

Functional Dyspepsia – Number of Cases by Country

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Country-wise Functional Dyspepsia Epidemiology Segment

The functional dyspepsia epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

Population-based studies from North America and Europe report a prevalence of 10–15%, with slightly higher rates in females and younger adults. The United States demonstrates a notable burden of functional dyspepsia, as reflected in multinational survey data applying the Rome IV criteria. Approximately 12% of U.S. adults were identified with functional dyspepsia in a sample of 1,949 respondents, highlighting its significant presence within the population. Evidence from clinical reviews further supports this prevalence estimate, reinforcing the condition’s ongoing relevance in primary care and gastroenterology settings. Overall, these figures underscore the need for sustained awareness and improved care pathways across the U.S. healthcare landscape.

Functional Dyspepsia: Treatment Overview

Treatment for functional dyspepsia targets symptoms and underlying physiological disturbances. Common approaches include proton pump inhibitors, H. pylori eradication when indicated, prokinetics, neuromodulators, and dietary adjustments. Psychological interventions such as cognitive-behavioral therapy benefit patients with gut-brain axis involvement. Emerging therapies targeting gastric accommodation and hypersensitivity offer new possibilities. Given FD’s chronicity and multifactorial nature, personalized treatment strategies are essential. Increased research attention is driving development of more precise pharmacologic options and improved algorithms to enhance long-term symptom control and overall patient quality of life.

Key Questions Answered

  • What are the key findings of functional dyspepsia epidemiology in the 8 major markets?
  • What will be the total number of patients with functional dyspepsia across the 8 major markets during the forecast period?
  • What was the country-wise functional dyspepsia epidemiology scenario in the 8 major markets in the historical period?
  • Which country will have the highest number of cases of functional dyspepsia during the forecast period of 2026-2035?
  • Which key factors would influence the shift in the patient population of functional dyspepsia during the forecast period of 2026-2035?
  • What are the currently available treatments for functional dyspepsia?
  • What are the disease risks, signs, symptoms, and unmet needs of functional dyspepsia?

Scope of the Functional Dyspepsia Epidemiology Report

  • The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of functional dyspepsia based on several factors.
  • Functional Dyspepsia Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
  • The functional dyspepsia report helps to identify the patient population, and the unmet needs are highlighted along with an assessment of the disease's risk and burden.

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Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

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Details 

Base Year 

2025

Historical Period

2019-2025

Forecast Period

2026-2035

Epidemiology Statistics Provided

  • Diagnosed Prevalent Cases
  • Type-Specific Cases
  • Gender-Specific Cases
  • Age-Specific Cases

Segmentation Provided

  • Epidemiology by Age Group
  • Epidemiology by Gender
  • Epidemiology by Type of Disease
  • Epidemiology by Region

Geographies Covered 

  • United States
  • Germany
  • Italy
  • France
  • Spain
  • United Kingdom
  • Japan
  • India

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