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Report Overview

Keratoconus in the United States remains rare but impactful, affecting young adults across genders and racial groups, emphasizing the importance of early detection, screening, and timely ophthalmologic intervention. As per keratoconus epidemiology forecast by Expert Market Research, the condition presents in the second to third decades (ages ~20-30) and progression is more likely in younger patients.

2025

Base Year

2019-2025

Historical Period

2026-2035

Forecast Period

Keratoconus - Number of Cases by Year

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Keratoconus Epidemiology Forecast Report Coverage

Expert Market Research's “Keratoconus Epidemiology Forecast Report 2026-2035” offers comprehensive information on the prevalence and demographics of keratoconus. It projects the future incidence and prevalence rates of keratoconus cases across various populations. The study covers age, gender, and type as major determinants of the keratoconus population. The report highlights patterns in the prevalence of keratoconus over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on keratoconus epidemiology in the 8 major markets.

Regions Covered

  • The United States
  • Germany
  • France
  • Italy
  • Spain
  • The United Kingdom
  • Japan
  • India

Keratoconus Understanding: Disease Overview

Keratoconus is a progressive, non-inflammatory ectatic corneal disorder characterized by thinning and cone-shaped protrusion, leading to visual distortion. It typically manifests in adolescence and progresses until the third or fourth decade. The etiology is multifactorial, involving genetic predisposition, oxidative stress, and environmental factors like eye rubbing and atopy. Prevalence is increasing globally with improved diagnostic imaging. The condition severely impairs vision quality if untreated and may progress to corneal scarring, necessitating surgical intervention in advanced cases.

Keratoconus Epidemiology Perspective

The keratoconus epidemiology division offers information on the patient pool from history to the present, as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for the keratoconus epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for keratoconus and their trends. The keratoconus detailed epidemiology segmentation is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.

  • The global pooled prevalence of keratoconus is estimated at 289 per 100,000 people, indicating that roughly 0.24% of the population worldwide currently lives with this progressive corneal disorder.
  • The pooled incidence of keratoconus is about 4 new cases per 100,000 person-years, reflecting the relatively rare but clinically significant emergence of the disease each year globally.
  • Young adults aged 25-29 years bear the highest burden, with prevalence reaching 525 per 100,000 and incidence about 20.8 per 100,000 person-years, highlighting early adulthood as a critical risk period.
  • Gender patterns indicate that males have slightly higher susceptibility, with an odds ratio of 1.10. This suggests modest but consistent male predominance in keratoconus occurrence worldwide.

Keratoconus – Number of Cases by Country

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Country-wise Keratoconus Epidemiology Segment

The keratoconus epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

In the United States, keratoconus remains a relatively rare but clinically significant corneal disorder, with a prevalence of approximately 0.04% among Medicaid and CHIP enrollees in 2019, slightly up from 0.03% in 2016. The condition affects both males and females, with modest variations across age and racial groups. Although uncommon, keratoconus can lead to visual impairment if undiagnosed or untreated. Continued awareness, timely screening, and access to appropriate ophthalmologic care are essential to ensure early detection and optimal management, reducing long-term complications for affected individuals.

Keratoconus: Treatment Overview

The management focuses on halting progression and improving vision. Early stages are treated with spectacles or rigid gas-permeable contact lenses to correct irregular astigmatism. Corneal collagen cross-linking (CXL) is the only proven method to stabilize the disease by strengthening stromal fibers. Intracorneal ring segments, topography-guided photorefractive keratectomy, and advanced scleral lenses provide visual rehabilitation. In severe or scarred corneas, penetrating or deep anterior lamellar keratoplasty is performed. Ongoing research explores gene therapy and customized CXL protocols to enhance outcomes.

Key Questions Answered

  • What are the key findings of keratoconus epidemiology in the 8 major markets?
  • What will be the total number of patients with keratoconus across the 8 major markets during the forecast period?
  • What was the country-wise keratoconus epidemiology scenario in the 8 major markets in the historical period?
  • Which country will have the highest number of cases of keratoconus during the forecast period of 2026-2035?
  • Which key factors would influence the shift in the patient population of keratoconus during the forecast period of 2026-2035?
  • What are the currently available treatments for keratoconus?
  • What are the disease risks, signs, symptoms, and unmet needs of keratoconus?

Scope of the Keratoconus Epidemiology Report

  • The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of keratoconus based on several factors.
  • Keratoconus Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
  • The keratoconus report helps to identify the patient population, and the unmet needs are highlighted along with an assessment of the disease's risk and burden.

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Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

Report Features 

Details 

Base Year 

2025

Historical Period

2019-2025

Forecast Period

2026-2035

Epidemiology Statistics Provided

  • Diagnosed Prevalent Cases
  • Type-Specific Cases
  • Gender-Specific Cases
  • Age-Specific Cases

Segmentation Provided

  • Epidemiology by Age Group
  • Epidemiology by Gender
  • Epidemiology by Type of Disease
  • Epidemiology by Region

Geographies Covered 

  • United States
  • Germany
  • Italy
  • France
  • Spain
  • United Kingdom
  • Japan
  • India

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