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A 2020 meta-analysis encompassing 85 studies with over 6.6 million individuals estimated that 8.2% of the global population is affected by palmar fibromatosis (also known as Dupuytren’s disease). The palmar fibromatosis epidemiology forecast by Expert Market Research indicates that males are more susceptible to develop the condition as compared to females.
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Expert Market Research's “Palmar fibromatosis Epidemiology Forecast Report 2026-2035” offers comprehensive information on the prevalence and demographics of palmar fibromatosis. It projects the future incidence and prevalence rates of palmar fibromatosis cases across various populations. The study covers age, gender, and type as major determinants of the palmar fibromatosis population. The report highlights patterns in the prevalence of palmar fibromatosis over time and projects future trends based on multiple variables.
The report provides a comprehensive overview of the disease, as well as historical and projected data on palmar fibromatosis epidemiology in the 8 major markets.
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Palmar fibromatosis, or Dupuytren’s Disease, is a fibroproliferative disorder affecting the palmar fascia, marked by abnormal collagen deposition and myofibroblast proliferation. The disease begins with painless nodules in the palm, progressing to fibrous cords that tether the fingers, leading to fixed flexion contractures and impaired hand function. Histologically, it involves myofibroblast activity, excessive type III collagen accumulation, and altered growth factor signaling. Without treatment, progressive contractures may significantly impair daily activities, making early recognition and intervention essential for preserving hand mobility.
The palmar fibromatosis epidemiology division offers information on the patient pool from history to the present, as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for the palmar fibromatosis epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for palmar fibromatosis and its trends. The palmar fibromatosis detailed epidemiology segmentation is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.

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The palmar fibromatosis epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.
Recent epidemiological analyses have highlighted a significant rise in palmar fibromatosis burden across the United States. Between 2016 and 2022, a comprehensive claims dataset identified 119,793 diagnosed cases, with numbers steadily increasing to approximately 22,711 cases in 2022. Experts attribute this trend to aging demographics, improved diagnostic accuracy, and growing disease awareness among both patients and clinicians. These findings emphasize the importance of enhanced surveillance systems and strategic healthcare planning to effectively manage the expanding clinical and surgical needs associated with Dupuytren’s disease.
Treatment for palmar fibromatosis aims to restore hand function and prevent further contracture progression. Conservative approaches include physiotherapy and splinting in early stages. For significant functional impairment, minimally invasive options such as collagenase clostridium histolyticum injections or needle aponeurotomy are widely used. Surgical interventions, such as limited fasciectomy or dermofasciectomy, remain the gold standard for advanced disease with severe contractures. Recurrence rates vary, necessitating long-term follow-up and postoperative rehabilitation to optimize outcomes and maintain functional range of motion.
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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Base Year |
2025 |
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Historical Period |
2019-2025 |
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Forecast Period |
2026-2035 |
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