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Report Overview

The global prevalence of progressive pulmonary fibrosis (PPF) is estimated between 6.9 and 70.3 cases per 100,000 individuals, with incidence ranging from 2.1 to 32.6 cases per 100,000 person‑years, figures that underscore the substantial and growing burden of this rare lung disease worldwide. Progressive pulmonary fibrosis epidemiology forecast indicates that the prevalence is expected to increase in the forecast period, propelling the demand for effective treatment alternatives.

2025

Base Year

2019-2025

Historical Period

2026-2035

Forecast Period

Progressive Pulmonary Fibrosis Number Of Cases By Year
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Progressive Pulmonary Fibrosis Epidemiology Forecast Report Coverage

Expert Market Research's “Progressive Pulmonary Fibrosis Epidemiology Forecast Report 2026-2035” offers comprehensive information on the prevalence and demographics of progressive pulmonary fibrosis. It projects the future incidence and prevalence rates of progressive pulmonary fibrosis cases across various populations. The study covers age, gender, and type as major determinants of the progressive pulmonary fibrosis population. The report highlights patterns in the prevalence of progressive pulmonary fibrosis over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of progressive pulmonary fibrosis in the 8 major markets.

Regions Covered

  • The United States
  • Germany
  • France
  • Italy
  • Spain
  • The United Kingdom
  • Japan
  • India

Progressive Pulmonary Fibrosis Understanding: Disease Overview

Progressive pulmonary fibrosis (PPF) describes a worsening pattern of fibrosis in interstitial lung diseases (ILDs) like IPF, hypersensitivity pneumonitis, and connective tissue disease-associated ILD. PPF leads to irreversible scarring, reduced lung function, and respiratory failure over time. Symptoms include chronic cough, exertional breathlessness, and fatigue. Diagnosis relies on imaging, pulmonary function tests, and sometimes a biopsy. PPF reflects a distinct disease behavior characterized by steady, often relentless, progression despite treatment.

Progressive Pulmonary Fibrosis Epidemiology Perspective

The progressive pulmonary fibrosis epidemiology division offers information on the patient pool from history to the present, as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for the progressive pulmonary fibrosis epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for progressive pulmonary fibrosis and its trends. The progressive pulmonary fibrosis epidemiology segmentation is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.

  • The global incidence of progressive pulmonary fibrosis (PPF) ranges between 2.1 and 32.6 cases per 100,000 person-years, highlighting its classification as a rare yet notable lung condition.
  • Prevalence estimates for PPF globally fall between 6.9 and 70.3 cases per 100,000 individuals, reflecting varying detection rates and increasing awareness across different regions.
  • A Japanese cohort study reported a 5-year survival rate of approximately 72.8% for PPF patients, significantly higher than the 53.7% observed in idiopathic pulmonary fibrosis cases.

Progressive Pulmonary Fibrosis Number Of Cases By Country
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Country-wise Progressive Pulmonary Fibrosis Epidemiology Segment

The progressive pulmonary fibrosis epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

Progressive pulmonary fibrosis (PPF) continues to present a significant health concern in both the United States and Japan, with emerging data highlighting its growing prevalence. In the United States, physician surveys estimate that approximately 18% to 32% of patients with fibrosing interstitial lung diseases (ILDs) develop a progressive fibrotic phenotype, with the overall prevalence of progressive fibrosing ILDs reported at around 28 per 100,000 individuals. Similarly, in Japan, a large-scale analysis of 34,960 ILD patients (non-IPF) found that 41.7% progressed to PPF within 24 months, with a 24-month cumulative progression rate of 39.5%, underscoring rapid disease progression in the Japanese population. These findings highlight PPF's significant impact and underscore the need for early detection and treatment strategies across both nations.

Progressive Pulmonary Fibrosis: Treatment Overview

Treatment strategies focus on slowing fibrosis progression and preserving lung function. Antifibrotic agents like nintedanib or pirfenidone are commonly used to reduce lung function decline. Supportive care includes pulmonary rehabilitation, oxygen therapy, and management of comorbidities. In advanced cases, lung transplantation is considered. Early identification of progression helps optimize outcomes, and ongoing clinical trials continue exploring targeted therapies to improve survival and quality of life.

Key Questions Answered

  • What are the key findings of progressive pulmonary fibrosis epidemiology in the 8 major markets?
  • What will be the total number of patients with progressive pulmonary fibrosis across the 8 major markets during the forecast period?
  • What was the country-wise progressive pulmonary fibrosis epidemiology scenario in the 8 major markets in the historical period?
  • Which country will have the highest number of progressive pulmonary fibrosis patients during the forecast period of 2026-2035?
  • Which key factors would influence the shift in the patient population of progressive pulmonary fibrosis during the forecast period of 2026-2035?
  • What are the currently available treatments for progressive pulmonary fibrosis?
  • What are the disease risks, signs, symptoms, and unmet needs of progressive pulmonary fibrosis?

Scope of the Progressive Pulmonary Fibrosis Epidemiology Report

  • The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of progressive pulmonary fibrosis based on several factors.
  • Progressive Pulmonary Fibrosis Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
  • The progressive pulmonary fibrosis report helps to identify the patient population, and the unmet needs are highlighted along with an assessment of the disease's risk and burden.

Related Reports

Idiopathic Pulmonary Fibrosis Treatment Market Report 

Cystic Fibrosis Epidemiology Forecast

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Report Summary

Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

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Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

Report Features 

Details 

Base Year 

2025

Historical Period

2019-2025

Forecast Period

2026-2035

Epidemiology Statistics Provided

  • Diagnosed Prevalent Cases
  • Type-Specific Cases
  • Gender-Specific Cases
  • Age-Specific Cases

Segmentation Provided

  • Epidemiology by Age Group
  • Epidemiology by Gender
  • Epidemiology by Type of Disease
  • Epidemiology by Region

Geographies Covered 

  • United States
  • Germany
  • Italy
  • France
  • Spain
  • United Kingdom
  • Japan
  • India

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