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Polycystic kidney disease (PKD) refers to a genetic disorder that is characterized by the formation of fluid-filled sacs (cysts) in the kidneys. The disease can result in serious complications, including high blood pressure and kidney failure. The increasing prevalence of polycystic kidney disease, especially the autosomal dominant form, is expected to fuel the market growth. The rising advancements in drug development and the growth in new drug approvals are poised to augment the market demand. Additionally, the growing focus on symptom management and the rise in clinical trials are likely to influence the polycystic kidney disease drugs market landscape.
Autosomal dominant polycystic kidney disease constitutes the more prevalent form of polycystic kidney disease, affecting 1 in 400 to 1000 individuals. On the other hand, autosomal recessive polycystic kidney is reported to have an estimated prevalence of 1 in 20,000 to 40,000 people. The increasing prevalence of polycystic kidney disease is one of the key factors propelling the demand for effective medications that can slow disease progression and manage symptoms.
Based on the disease type, the market segmentation includes autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD), among other rare forms. Autosomal dominant polycystic kidney disease is an inherited genetic disorder that causes the development of numerous cysts in the kidneys and results in progressive kidney damage over time. The drug tolvaptan shows high efficacy in slowing the progression of kidney function decline in autosomal dominant polycystic kidney disease and thus is commonly used for the treatment of the condition. The market is witnessing a growing demand for medications that help in symptom management of ADPKD such as hypertension, pain, and kidney infections, which is likely to contribute to the market expansion in the coming years.
The market report also offers insights based on the mechanism of action, route of administration, end-user, and region.
The market segmentation by region includes the United States, EU-4 (Germany, France, Italy, Spain), and the United Kingdom, Japan, and India. The United States is projected to dominate the market for polycystic kidney disease drugs due to the high prevalence of autosomal dominant polycystic kidney disease and the presence of a well-established healthcare system. The robust regulatory framework and the growing demand for innovative therapies also support the market growth. Moreover, the rising R&D investment in rare and genetic diseases and increasing healthcare spending are anticipated to boost the market expansion in the country.
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