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Metronidazole Prices, Demand and Supply Overview
Metronidazole prices in Germany, the highest-cost reporting region, rose 5.9% in H1 2026, climbing from USD 40.4/KG in Q1 to USD 42.8/KG by Q2 as spring antiprotozoal and anaerobic infection treatment procurement and firmer nitroimidazole synthesis feedstock costs drove consistent buying following the brief Q1 2026 pricing correction. Globally, the average rose from USD 28.55/KG in Q1 to USD 30.26/KG in Q2, a 6.0% gain. For H2 2026, a global average of USD 30.50-34.20/KG is expected, with continued firming on Middle East supply disruptions and growing antiprotozoal and anaerobic infection treatment sector demand globally.
Metronidazole is a 5-nitroimidazole antibiotic and antiprotozoal active pharmaceutical ingredient produced by multi-step chemical synthesis starting from 2-methyl-5-nitroimidazole, which is N-hydroxyethylated through reaction with ethylene oxide or 2-chloroethanol under basic conditions to introduce the 2-hydroxyethyl side chain at the N-1 position, giving the 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole active structure. The compound exerts its antimicrobial and antiprotozoal activity through reductive activation of the 5-nitro group by microbial ferredoxin or similar electron-transport proteins in anaerobic and microaerophilic organisms, generating cytotoxic nitroso and hydroxylamine intermediates that cause strand breaks in microbial DNA. The largest pull comes from treatment of bacterial vaginosis and Trichomonas vaginalis infections, where oral and topical vaginal gel formulations are first-line therapy. Anaerobic bacterial infection treatment including intra-abdominal sepsis, pelvic inflammatory disease, brain abscess, and surgical prophylaxis adds the next largest demand segment. Giardia lamblia and Entamoeba histolytica antiprotozoal treatment, Clostridium difficile infection management, Helicobacter pylori eradication combination regimens, and topical rosacea treatment add further demand. Synthesis feedstock costs, antiprotozoal prescription volumes, and regional API production capacity all feed into the price.
Metronidazole Price Forecast for 2026
The balance of supply and demand for metronidazole through H2 2026 leans moderately firm. Nitroimidazole synthesis feedstock costs firmed from Middle East chemical supply disruptions. Bacterial vaginosis treatment, anaerobic infection management, and antiprotozoal access programme distribution are growing with expanding women’s health and infectious disease treatment coverage globally.
The main upside risk is synthesis feedstock cost increases alongside accelerating bacterial vaginosis treatment and anaerobic infection management demand. The main downside risk is continued Chinese API surplus and generic competition limiting the global price recovery.
| Region | Price Forecast (USD/KG) | Key Driver |
| Global Average | 30.50 - 34.20 | Synthesis cost firming and antiprotozoal/anaerobic demand support |
| United States | 32.60 - 36.30 | Steady BV treatment and anaerobic infection demand holds firm |
| China | 22.90 - 26.60 | Large API capacity keeps it the most affordable |
| Germany | 43.10 - 46.80 | High synthesis and energy costs keep it the most expensive |
| India | 31.50 - 35.20 | Growing antiprotozoal and export Rx demand holds a firm middle |
For the Quarter Ending June 2026
Metronidazole Prices Q2 2026:
- United States: USD 34.8/KG
- China: USD 24.1/KG
- Germany: USD 42.8/KG
- India: USD 33.1/KG
Metronidazole Prices in the United States
US Metronidazole prices averaged USD 34.8/KG in Q2 2026, up 6.1% from USD 32.8/KG in Q1 2026. Firmer synthesis feedstock costs and spring bacterial vaginosis and anaerobic infection treatment procurement drove consistent buying following the Q1 correction.
Why did the price of Metronidazole change in Q2 2026 in the United States?
Firmer nitroimidazole synthesis feedstock costs raised the API production floor. Bacterial vaginosis, trichomoniasis, and anaerobic infection treatment procurement lifted buying. H. pylori eradication and Giardia treatment demand provided additional support near USD 34.8/KG.
Metronidazole Prices in China
Chinese Metronidazole prices averaged USD 24.1/KG in Q2 2026, up 6.2% from USD 22.7/KG in Q1 2026, the lowest among the tracked markets. Spring antiprotozoal and anaerobic infection export and domestic procurement lifted buying. Firmer domestic synthesis costs raised the production floor despite domestic API capacity.
Why did the price of Metronidazole change in Q2 2026 in China?
Spring antiprotozoal and anaerobic infection treatment export and domestic procurement lifted buying. Firmer domestic nitroimidazole synthesis costs raised the production floor. Domestic API capacity kept China the most affordable source.
Metronidazole Prices in Germany
German Metronidazole prices averaged USD 42.8/KG in Q2 2026, up 5.9% from USD 40.4/KG in Q1 2026, the highest among the tracked markets. Higher synthesis feedstock and energy costs elevated European API production economics. Consistent bacterial vaginosis, anaerobic infection, and antiprotozoal treatment demand maintained steady buying.
Why did the price of Metronidazole change in Q2 2026 in Germany?
Higher nitroimidazole synthesis feedstock and energy costs elevated European API production economics. Middle East supply disruptions added cost premiums to synthesis feedstock supply chains. Consistent bacterial vaginosis and anaerobic infection treatment procurement maintained buying near USD 42.8/KG.
Metronidazole Prices in India
Indian Metronidazole prices averaged USD 33.1/KG in Q2 2026, up 6.1% from USD 31.2/KG in Q1 2026. Growing antiprotozoal export and domestic anaerobic infection demand supported buying. Firmer synthesis import costs raised the production floor through the quarter.
Why did the price of Metronidazole change in Q2 2026 in India?
Growing antiprotozoal and bacterial vaginosis export and domestic procurement lifted buying. Firmer nitroimidazole synthesis import costs raised the production floor. Southeast Asian and African antiprotozoal export demand provided additional support near USD 33.1/KG.
For the Quarter Ending March 2026
Metronidazole Prices Q1 2026:
- United States: USD 32.8/KG
- China: USD 22.7/KG
- Germany: USD 40.4/KG
- India: USD 31.2/KG
Metronidazole Prices in the United States
US Metronidazole prices averaged USD 32.8/KG in Q1 2026, easing about 2.0% from Q4 2025. Post-year-end antiprotozoal and anaerobic infection procurement moderation and soft synthesis costs eased the market before the Q2 spring procurement recovery.
Why did the price of Metronidazole change in Q1 2026 in the United States?
Post-year-end bacterial vaginosis and anaerobic infection procurement moderation reduced buying urgency. Soft synthesis feedstock costs eased the production floor. The market eased to USD 32.8/KG before the Q2 spring antiprotozoal procurement recovery.
Metronidazole Prices in China
Chinese prices averaged USD 22.7/KG in Q1 2026, easing about 2.2% from Q4 2025. Post-Lunar New Year procurement moderation and soft synthesis costs held the market near USD 22.7/KG.
Why did the price of Metronidazole change in Q1 2026 in China?
Post-Lunar New Year antiprotozoal export and domestic procurement moderation reduced urgency. Soft domestic synthesis costs eased the production floor. The market eased to USD 22.7/KG before the Q2 recovery.
Metronidazole Prices in Germany
German prices averaged USD 40.4/KG in Q1 2026, easing about 1.9% from Q4 2025. Post-year-end antiprotozoal and anaerobic infection procurement moderation and soft synthesis costs eased the market near USD 40.4/KG.
Why did the price of Metronidazole change in Q1 2026 in Germany?
Post-year-end bacterial vaginosis and anaerobic infection procurement moderation reduced buying urgency. Soft synthesis feedstock and energy costs eased the production floor. The market eased to USD 40.4/KG before the Q2 spring procurement recovery.
Metronidazole Prices in India
Indian prices averaged USD 31.2/KG in Q1 2026, easing about 1.9% from Q4 2025. Post-holiday procurement moderation and soft synthesis costs held the market near USD 31.2/KG.
Why did the price of Metronidazole change in Q1 2026 in India?
Post-holiday antiprotozoal and anaerobic procurement moderation reduced urgency. Soft synthesis import costs eased the floor. The market eased to USD 31.2/KG before the Q2 spring recovery.
Quarterly Metronidazole Price Trends
Global Metronidazole prices firmed through Q3 and Q4 2025 on the antiprotozoal and anaerobic infection treatment season, corrected in Q1 2026 on post-year-end procurement moderation, then surged in Q2 2026. The average rose from USD 28.0/KG in Q2 2025 to USD 28.56/KG in Q3 and USD 29.13/KG in Q4, eased to USD 28.55/KG in Q1 2026, then surged to USD 30.26/KG in Q2 2026, a net gain of about 8.0% over the window. Nitroimidazole synthesis feedstock cycles and antiprotozoal and anaerobic infection treatment procurement seasonality drove the overall pattern.
| Quarter | Price (USD/KG) | QoQ Change | Direction |
| Q2 2026 | 30.26 | +6.0% | ↑ Rising |
| Q1 2026 | 28.55 | -2.0% | ↓ Falling |
| Q4 2025 | 29.13 | +2.0% | ↑ Rising |
| Q3 2025 | 28.56 | +2.0% | ↑ Rising |
| Q2 2025 | 28.0 | - | - Stable |
| Q3 2026 | In Progress | - | - In Progress |
What was Metronidazole Price in 2025?
Metronidazole prices firmed steadily through 2025 on consistent antiprotozoal and anaerobic infection treatment demand. The global average opened near USD 27.5/KG in Q1 2025 and closed at USD 29.13/KG in Q4, a full-year gain of about 5.9%. Synthesis feedstock cost dynamics and bacterial vaginosis and anaerobic infection treatment procurement drove the upward trajectory throughout the year.
Metronidazole Prices in the United States in 2025
US prices firmed from about USD 32.5/KG in Q1 2025 to USD 33.5/KG by Q4, a gain of 3.1%. Consistent bacterial vaginosis, trichomoniasis, and anaerobic infection treatment demand supported the upward trend.
Metronidazole Prices in China in 2025
Chinese prices firmed from roughly USD 22.5/KG in Q1 2025 to USD 23.2/KG by Q4, a gain of 3.1%. Growing antiprotozoal export and domestic anaerobic treatment demand drove the firming through the year.
Metronidazole Prices in Germany in 2025
German prices firmed from about USD 40.0/KG in Q1 2025 to USD 41.2/KG by Q4, a gain of 3.0%. Consistent bacterial vaginosis, anaerobic infection, and rosacea treatment demand and firm synthesis costs supported the market throughout the year.
Metronidazole Prices in India in 2025
Indian prices firmed from roughly USD 30.8/KG in Q1 2025 to USD 31.8/KG by Q4, a gain of 3.2%. Growing antiprotozoal and anaerobic infection export and domestic demand drove consistent firming.
How We Can Help
Expert Market Research: Your Source for Real-Time Metronidazole Price Intelligence
Expert Market Research tracks Metronidazole prices continuously across every major producing and consuming region. The team traces causation through nitroimidazole synthesis feedstock economics, antiprotozoal and anaerobic infection treatment procurement cycles, and regional API production capacity. Contact Expert Market Research today for Metronidazole pricing data, bespoke market analysis, and strategic procurement advisory.
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Key Questions Answered in the Report
Treatment of bacterial vaginosis and Trichomonas vaginalis infections as first-line therapy takes the largest share across oral and topical vaginal formulations. Anaerobic bacterial infection treatment including intra-abdominal sepsis, pelvic inflammatory disease, and surgical prophylaxis, Giardia and Entamoeba antiprotozoal treatment, H. pylori eradication combination therapy, and topical rosacea treatment also consume significant volumes globally.
The Q2 2026 average was USD 34.8/KG in the United States, USD 24.1/KG in China, USD 42.8/KG in Germany, and USD 33.1/KG in India. Germany remains the highest-priced market.
The global average rose from USD 28.55/KG in Q1 to about USD 30.26/KG in Q2, a gain of around 6.0%. Spring antiprotozoal and anaerobic infection treatment procurement and firmer synthesis feedstock costs drove the H1 recovery from the Q1 correction.
Post-year-end bacterial vaginosis and anaerobic infection treatment procurement moderation reduced buying urgency. Soft nitroimidazole synthesis feedstock costs eased the API production floor before the Q2 spring procurement recovery.
The global average is expected in the USD 30.50 to 34.20/KG range for H2 2026, with continued firming as synthesis feedstock costs stay elevated and antiprotozoal and anaerobic infection treatment demand grows globally.
Germany sits highest on synthesis and energy costs, the United States and India hold a firm middle on antiprotozoal and anaerobic treatment demand, and China prices lowest on domestic API capacity.
This report is updated monthly. For real-time pricing intelligence, contact the Expert Market Research team directly.
Prices respond mainly to nitroimidazole synthesis feedstock costs, bacterial vaginosis and anaerobic infection treatment prescription cycles, and Chinese API production discipline. Women’s health access programme scale and aromatic synthesis precursor prices are key signals.
China and India hold the largest metronidazole API production capacity. Any synthesis feedstock cost shift ripples across markets within one to two quarters.
Buyers can use quarterly trends and forecasts to time antiprotozoal and anaerobic infection formulation contracts around synthesis cost cycles, build cover when feedstock signals tighten, and monitor women’s health programme procurement as the primary demand signal.
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