The acute pain market was valued at USD 52.59 Billion in 2025, driven by the rising cases of acute pain-related conditions across the 8 major markets. The market is expected to grow at a CAGR of 5.11% during the forecast period of 2026-2035, with the values likely to reach USD 86.57 Billion by 2035.
Base Year
Historical Period
Forecast Period
The increasing prevalence of acute pain conditions, such as post-surgical pain, trauma, and sports injuries, is driving the demand for effective pain management solutions.
A major market trend is the rising shift towards non-opioid pain management solutions due to the increasing concerns about opioid addiction and misuse.
The growing number of clinical trials assessing novel acute pain management drugs and the presence of a favorable regulatory environment is impacting the market dynamics.
Compound Annual Growth Rate
5.11%
Value in USD Billion
2026-2035
*this image is indicative*
Acute pain is characterized by intense or sharp pain including localized throbbing, sensations of burning or painful tingling, and localized numbness, among others. Unlike chronic pain, acute pain can last for a single day or up to 12 weeks. Acute pain can result from a physical injury such as a bone fracture, pulling a muscle, and developing an infection from an open wound.
The acute pain market is driven by the rising incidence of acute pain conditions. The need for acute pain treatments is also propelled by the growing aging population and the increase in the volume of medical procedures. The heightened awareness among patients and healthcare providers about the importance of timely and effective pain management is also contributing to the market demand. The development of new medications and non-pharmacological therapies that offer better efficacy and fewer side effects is expected to fuel the market growth. Moreover, the rising demand for non-opioid pain management solutions and increased focus on biologics and regenerative medicine is projected to shape the market landscape positively.
Development of Novel Acute Pain Management Treatments to Impact Market Growth
In August 2024, Vertex Pharmaceuticals Incorporated, an American biopharmaceutical company, announced that its New Drug Application for suzetrigine, an investigational oral non-opioid painkiller, was approved by the US Food and Drug Administration (FDA). The drug candidate, representing a novel class of analgesics, is intended to treat moderate-to-severe acute pain and has been granted priority evaluation by the FDA. The development of such innovative acute pain therapy is anticipated to fuel the market growth in the forecast period.
The market is witnessing several trends and developments to improve the current scenario. Some of the notable trends are as follows:
"Acute Pain Market Report and Forecast 2026-2035" offers a detailed analysis of the market based on the following segments:
Market Breakup by Drug Class
Market Breakup by Form
Market Breakup by Indication
Market Breakup by Distribution Channel
Market Breakup by Region
Drug Class Segment is Poised to Witness Substantial Growth
The market segmentation by drug class includes NSAIDs, anesthetics, anticonvulsants, anti-migraine agents, antidepressants, analgesics, and others. The NSAIDs (non-steroidal anti-inflammatory drugs) segment holds a major market share as they are often the first-line treatment for acute pain like post-surgical pain, musculoskeletal injuries, and headaches. This drug class is popular due to its effectiveness in reducing inflammation and providing pain relief with fewer side effects in comparison to opioids. Additionally, the easy accessibility of NSAIDs as over-the-counter medications further boosts the growth of the segment.
The market segmentation by region includes the United States, EU-4 (Germany, France, Italy, Spain), and the United Kingdom, Japan, and India. The United States dominates the market share for acute pain, owing to the high prevalence of pain-related conditions, such as post-surgical pain, trauma, and sports injuries. The growing demand for innovative pain management therapies, including both pharmacological and non-pharmacological options, also supports the market growth. Further, the rising shift towards non-opioid pain management alternatives in the country is poised to influence the market dynamics.
The key features of the market report comprise patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, and strategic initiatives by the leading key players. The major companies in the market are as follows:
Biopharmaceutical giant Pfizer is one of the leading players in the market and is known for its broad portfolio of medications. The company provides acute pain management solutions including analgesics, such as NSAIDs and opioids.
Abbott Laboratories, headquartered in Illinois, United States, has a significant market presence in pain management and is focused on meeting the consumer demand for safer, non-addictive pain therapies. The company is known for its expertise in developing non-opioid pain management solutions and advanced pain relief technologies.
GSK plc is a British multinational pharmaceutical company that specializes in developing innovative pain relief medications, including both over the counter and prescription options. The company invests in research to develop new treatments for different types of pain with fewer side effects.
Novartis AG, based in Basel, Switzerland, is an innovative medicines company offering a variety of medications that target acute pain. The company is engaged in developing targeted therapies that can provide more effective pain control with fewer side effects.
*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*
Other key players in the market include Purdue Pharma LP, Sun Pharmaceutical, Eli Lily and Company, Intas Pharma, Johnson & Johnson Services Inc., and Sanofi.
Acute Pain Drug Pipeline Analysis
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*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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| REPORT FEATURES | DETAILS |
| Base Year | 2025 |
| Historical Period | 2019-2025 |
| Forecast Period | 2026-2035 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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| Breakup by Drug Class |
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| Breakup by Form |
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| Breakup by Indication |
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| Breakup by Distribution Channel |
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| Breakup by Region |
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| Market Dynamics |
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| Supplier Landscape |
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| Companies Covered |
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