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Report Overview

The anaphylaxis treatment market was valued at USD 2.32 Billion in 2025 and is expected to grow at a CAGR of 6.40%, reaching USD 4.31 Billion by 2035. The market growth is driven by the rising incidence of allergies and food-related anaphylactic reactions, as well as increasing awareness and accessibility of epinephrine auto-injectors and emergency medical care across the 8 major markets. The market is fueled by the increasing availability of advanced epinephrine delivery devices and growing public awareness. Rising healthcare spending and improved emergency response infrastructure are expected to support market expansion. 

Key Market Trends and Insights

  • Food allergies will lead the allergen type. Peanuts are the most common type of food allergen and accounted for nearly USD 1500 million revenue in 2024.
  • Based on the drug class, epinephrine is expected to remain the leading class in anaphylaxis treatment.
  • United States is expected to lead the market in the forecast period.

Market Size and Forecast

  • Market Size (2025): USD 2.32 Billion
  • Projected Market Size (2035): USD 4.31 Billion
  • CAGR (2026-2035): 6.40% 
  • Largest Market in 2025: United States
     
2025

Base Year

2019-2025

Historical Period

2026-2035

Forecast Period

  • In February 2024, the FDA approved Xolair to reduce allergic reactions, including the risk of anaphylaxis, from accidental exposure to multiple foods, an advancement expected to significantly boost anaphylaxis treatment market growth.

  • Factors such as rising prevalence of food, drug, and insect–triggered anaphylaxis, combined with increased public awareness initiatives, government mandates, and innovations in delivery formats are accelerating market expansion

  • The market growth is further propelled by the involvement of various stakeholders, including pharmaceutical firms, biotech innovators, and device manufacturers, who are enhancing treatment efficacy, affordability, and global accessibility.

Anaphylaxis Treatment Market Overview

Anaphylaxis treatment involves prompt administration of epinephrine, followed by supportive care such as antihistamines, corticosteroids, and oxygen therapy to stabilize the patient and prevent recurrence. Rapid response is critical to reduce the risk of complications and fatal outcomes. The market is witnessing growth due to rising allergy prevalence, increased awareness, and improved access to emergency care. The market was valued at USD 2.32 Billion in 2025 and is expected to expand with advancements in auto-injector technology and broader distribution channels. Supportive government initiatives and increasing incidence of anaphylactic reactions further drive market demand across developed and emerging economies.

Anaphylaxis Treatment Market Growth Drivers

Rising Incidence of Anaphylaxis to Enhance Market Growth

The increasing prevalence of anaphylaxis is a significant growth driver of the treatment market. According to Kevin McLendon et al. 2023, the incidence of anaphylaxis in the United States doubled over the past two decades, with approximately 1,500 deaths reported annually. This alarming rise underscores the urgent need for effective emergency treatments and preventive therapies. Consequently, the demand for epinephrine auto-injectors and advanced biologics is projected to drive consistent market expansion.

Anaphylaxis Treatment Market Trends

Key trends in the market include the rise of needle-free innovations and the growing adoption of epicutaneous immunotherapy.

Needle-Free Innovations Driving Growth in the Market

The market is experiencing a notable shift toward innovative, patient-friendly solutions, particularly needle-free drug delivery systems. This trend addresses key concerns around needle phobia and delays in emergency treatment. For instance, in February 2025, ARS Pharmaceuticals advanced this movement by filing for the approval of neffy®, a needle-free epinephrine nasal spray, in Canada and the UK, following its 2024 approval in the U.S. and Europe. As acceptance of non-invasive treatments expands, this trend is expected to significantly boost global market growth.

Epicutaneous Immunotherapy Emerging as a Game-Changer in Pediatric Allergy Management and Boost Anaphylaxis Treatment Market Demand

A notable trend in the market is the development of innovative, non-invasive therapies targeting pediatric food allergies. In February 2025, DBV Technologies announced promising results from a three-year study of the VIASKIN® Peanut patch, showing improved peanut tolerance and sustained safety in toddlers. This advancement in epicutaneous immunotherapy signals strong potential to transform long-term allergy care and is expected to significantly boost market growth.

Anaphylaxis Treatment Market Share

Food Allergies to Lead the Market Share Based on Allergen Type

There are several allergens that can trigger life-threatening anaphylactic reactions, including food, insect stings, medications, and other environmental factors. In the anaphylaxis treatment market, segmentation by allergen type includes food allergies, insect allergies, drug allergies, and others. Among these, food allergies are expected to lead the market due to their rising global prevalence and increasing public health burden. According to the Food Allergy Research and Education (FARE) organization, approximately 33 million people in the United States alone have at least one food allergy. Notably, nearly 11% of U.S. adults, over 27 million individuals report suffering from food allergies. This rising incidence significantly drives the demand for rapid and effective treatment options, positioning food allergies as the dominant segment in the anaphylaxis treatment market.

Anaphylaxis Treatment Market Analysis by Region

The market is divided into regions such as the United States, the United Kingdom, Germany, France, Italy, Spain, Japan, and India. Among these, the United States remains dominant, bolstered by a robust healthcare infrastructure, strong regulatory support, and ongoing innovation. Notably, in June 2025, the FDA accepted Aquestive Therapeutics’ New Drug Application for Anaphylm, a sublingual epinephrine film for treating anaphylaxis and other type 1 allergic reactions. As a needle‑free, ultra‑portable alternative to traditional autoinjectors, Anaphylm addresses critical issues of compliance, convenience, and patient accessibility. This development underscores the United States’ position at the forefront of anaphylaxis treatment advancements.

Leading Players in the Anaphylaxis Treatment Market

The anaphylaxis treatment market research report by Expert Market Research provides an in-depth analysis of the competitive landscape, offering key insights into patent filings, grant analysis, funding trends, investments, and strategic initiatives by major players. It tracks recent investments, mergers, acquisitions, and partnerships that showcase the market's growth trajectory. Additionally, the report details strategic activities by leading companies, including regional expansions, adoption of new technologies, and efforts to enhance capacity, helping stakeholders better understand the market dynamics and positions of key industry players. Some of the leading players are as follows:

Viatris Inc.

Viatris Inc., a prominent healthcare company, is actively involved in the anaphylaxis treatment market through its widely recognized EpiPen® and EpiPen® Jr. auto-injectors. These adrenaline-based emergency devices are indicated for the rapid treatment of severe allergic reactions triggered by foods, insect bites, drugs, or other allergens. Viatris continues to play a critical role in providing immediate, life-saving intervention for patients at risk of anaphylactic episodes.

Novartis AG

Novartis AG has strengthened its position in the anaphylaxis treatment market with the FDA approval of Xolair® (omalizumab) for children and adults with IgE-mediated food allergies. Xolair, developed in collaboration with Genentech, is the first and only FDA-approved biologic to reduce allergic reactions, including anaphylaxis, from accidental food exposure. This approval marks a critical advancement in long-term allergy management.

Amgen Inc.

Amgen Inc. is actively involved in the market through its biologic therapy, KRYSTEXXA® (pegloticase), primarily indicated for adults with uncontrolled gout. Recent data from the Phase 4 AGILE trial presented at ACR 2024 highlighted a 1.7% incidence of anaphylaxis in patients receiving shorter infusion durations. These findings underscore Amgen’s continued commitment to advancing safe and effective treatment options for complex inflammatory conditions.

Amneal Pharmaceuticals LLC.

Amneal Pharmaceuticals LLC, through its division Impax Laboratories, is actively involved in the anaphylaxis treatment market with its epinephrine injection, USP auto-injector. This product, the authorized generic of Adrenaclick®, is available in 0.15 mg and 0.3 mg doses and is currently distributed in pharmacies across the United States. Designed for emergency treatment of anaphylactic reactions, the auto-injector offers a low-cost, reliable alternative for patients and caregivers, reinforcing Amneal’s commitment to accessible, life-saving therapeutics.

*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*

Other key players in the market include AstraZeneca plc, Pfizer Inc., Teva Pharmaceutical Industries Ltd., Merck and Co., Inc., and Glaxosmithkline Plc.

Anaphylaxis Treatment Market Segmentation

The market report offers a detailed analysis of the market based on the following segments:

Market Breakup by Allergen Type

  • Food Allergies
  • Insect Allergies
  • Drug Allergies
  • Others

Market Breakup by Drug Class

  • Epinephrine
  • Antihistamines
  • Steroids
  • Beta-Agonist
  • Others

Market Breakup by Route of Administration

  • Oral
  • Parenteral
    • Intramuscular
    • Subcutaneous
    • Intravenous
  • Others

Market Breakup by Age Group

  • Pediatric
  • Geriatric
  • Adults

Market Breakup by Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Channels

Market Breakup by Region

  • United States
  • United Kingdom
  • Germany
  • France
  • Italy
  • Spain
  • Japan
  • India

Key Questions Answered in the Anaphylaxis Treatment Market Report

  • What was the anaphylaxis treatment market value in 2025?
  • What is the anaphylaxis treatment market forecast outlook for 2026-2035?
  • What are the major factors aiding the anaphylaxis treatment market demand?
  • How has the market performed so far, and how is it anticipated to perform in the coming years?
  • What are the market's major drivers, opportunities, and restraints?
  • What are the major Anaphylaxis Treatment market trends?
  • Which allergen type is expected to dominate the market segment?
  • Which drug class is projected to lead the market segment?
  • Which route of administration is anticipated to drive the market segment?
  • Which age group is expected to dominate the market segment?
  • Which distribution channel is likely to dominate the market segment?
  • Who are the key players involved in the anaphylaxis treatment market?
  • What are the current unmet needs and challenges in the market?
  • How are partnerships, collaborations, mergers, and acquisitions among the key market players shaping the market dynamics?

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Report Summary

Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

REPORT FEATURES DETAILS
Base Year 2025
Historical Period 2019-2025
Forecast Period 2026-2035
Scope of the Report

Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:

  • Allergen Type
  • Drug Class
  • Route of Administration
  • Age Group
  • Distribution Channel
  • Region
Breakup by Allergen Type
  • Food Allergies
  • Insect Allergies
  • Drug Allergies
  • Others
Breakup by Drug Class
  • Epinephrine
  • Antihistamines
  • Steroids
  • Beta-Agonist
  • Others
Breakup by Route of Administration
  • Oral
  • Parenteral
  • Others
Breakup by Age Group
  • Pediatric
  • Geriatric
  • Adults
Breakup by Distribution Channel
  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Channels
Breakup by Region
  • United States
  • United Kingdom
  • Germany
  • France
  • Italy
  • Spain
  • Japan
  • India
Market Dynamics
  • Market Drivers and Constraints
  • SWOT Analysis
  • PESTEL Analysis
  • Porter’s Five Forces Model 
  • Key Demand Indicators
  • Key Price Indicators
  • Industry Events, Initiatives, and Trends 
  • Value Chain Analysis
Supplier Landscape
  • Market Structure
  • Company Profiles
    • Financial Analysis
    • Product Portfolio
    • Demographic Reach and Achievements
    • Company News and Developments
    • Certifications
Companies Covered
  • Viatris Inc.
  • AstraZeneca plc
  • Novartis AG
  • Pfizer Inc.
  • Amgen Inc.
  • Teva Pharmaceutical Industries Ltd.
  • Glaxosmithkline Plc.
  • Amneal Pharmaceuticals LLC
  • Merck And Co., Inc.

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