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Global Bone Morphogenetic Proteins Market Size, Forecast: By Type: Recombinant Human Bone Morphogenetic Protein (rhBMP) - 2, Recombinant Human Bone Morphogenetic Protein (rhBMP) -7; By Application: Spinal Fusion, Trauma, Reconstructive Surgery, Oral-maxillofacial; Regional Analysis; Market Dynamics; Competitive Landscape; 2024-2032
Global Bone Morphogenetic Proteins Market Outlook
The global bone morphogenetic proteins market is expected to grow at a CAGR of 2.3% during the period 2024-2032. North America, Europe and Asia are likely to be key markets.
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Global Market Likely to be Driven by Uses in a Variety of Processes During the Formation and Maintenance of Organs such as Bone, Cartilage, and Muscle, Among Others
Bone morphogenetic proteins (BMPs) is the common name of a family of proteins, recognized first in extracts of demineralized bone that were capable of encouraging bone formation at ectopic sites. Bone morphogenetic proteins are present in small amounts in bone material (nearly 1 microgram/kg dry weight of bone). Generally, the term bone morphogenetic proteins describes a certain function of these proteins, which have been implicated also in many other processes. Bone morphogenetic proteins such as BMP2, BMP4, and BMP7 also play a role in the specification of hematopoietic tissue from the mesodermal germ layer.
Bone morphogenetic proteins belong to the family of transforming growth factors. Presently, nearly twenty different bone morphogenetic proteins have been identified, all with different degrees of tissue stimulating properties. Bone morphogenetic proteins play important roles in a broad range of processes during the formation and maintenance of organs such as bone, cartilage, muscle, kidney, and blood vessels. As deregulation of the bone morphogenetic protein activity at multiple steps in signal transduction is associated with several human diseases, therapeutic use of activators and inhibitors of bone morphogenetic proteins signaling would provide potential avenues for the treatment of human ailments caused by hypo- and hyperactivation of bone morphogenetic proteins signals.
Applications of Bone Morphogenetic Proteins in Domains Such as Dentistry, Orthopaedics, Sports Likely to Boost Market Growth
Bone tissue is a mineralized structure with complex metabolism, and given its mechanical functions, its structure must be adapted to bone function. Bone morphogenetic proteins group stimulates the formation of bone and cartilage and influences several non-osteogenic processes. Due to their osteogenic effect, bone morphogenetic proteins are employed in several areas of medicine, including dentistry, orthopaedics, sport and rehabilitation. Such applications are expected to drive the global bone morphogenetic proteins market. Recombinant human bone morphogenetic proteins (rhBMPs) are administered to the bone grafting site through surgery. Bone morphogenetic proteins stimulate bone growth naturally in the human body. These proteins that exist in the body can be produced, concentrated and placed in the area of the spine for spinal fusion to occur. More importantly, these can generate fusion without the need for any use of the patient’s own bone.
Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGFβ superfamily. It plays an important role in embryonic dorsalventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. Bone morphogenetic protein 2 is an effective osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. Bone morphogenetic protein 2 also plays a key role in cardiac morphogenesis and is expressed in multiple tissues including lung, spleen, brain, liver, prostate ovary and small intestine.
Advanced Solutions Likely to Stimulate Market Growth
InfuseTM Bone Graft is a premium product for autograft replacement due to its high osteoinductivity. Infuse bone graft is recombinant human bone morphogenetic protein-2 (rhBMP-2) applied to an absorbable collagen sponge carrier (ACS). One of the functions of the protein is to inspire natural bone formation. INFUSE® Bone Graft is a revolutionary bone graft that helps inspire natural bone formation and remodelling and circumvents the need to harvest bone from other parts of a patient’s body. Infuse has been on the market since 2002 and used in over 1 million patients across the world. Such solutions are expected to drive growth of the global bone morphogenetic proteins market. Infuse is indicated for certain spinal fusion procedures in skeletally mature patients with degenerative disc disease (DDD) from L2 to S1, as well as for treating certain acute, open tibial shaft fractures. Infuse is also approved for certain oral-maxillofacial procedures.
Market Segmentation
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By type, the market is segmented into:
- Recombinant Human Bone Morphogenetic Protein (rhBMP) - 2
- Recombinant Human Bone Morphogenetic Protein (rhBMP) -7
By application, the market is divided into:
- Spinal Fusion
- Trauma
- Reconstructive Surgery
- Oral-maxillofacial
By region, the market is classified into:
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East and Africa
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Key Industry Players in the Market
The report presents a detailed analysis of the following key players in the global bone morphogenetic proteins market, looking into their capacity, and latest developments like capacity expansions, plant turnarounds, and mergers and acquisitions:
- Thermo Fisher Scientific, Inc.
- Medtronic plc
- Prospec-Tany Technogene Ltd.
- Merck KGaA
- Others
The EMR report gives an in-depth insight into the industry by providing a SWOT analysis as well as an analysis of Porter’s Five Forces model.
Key Highlights of the Report
| REPORT FEATURES | DETAILS |
| Base Year | 2023 |
| Historical Period | 2017-2023 |
| Forecast Period | 2024-2032 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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| Breakup by Type |
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| Breakup by Application |
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| Breakup by Region |
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| Market Dynamics |
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| Competitive Landscape |
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| Companies Covered |
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*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.
1 Preface
2 Report Coverage – Key Segmentation and Scope
3 Report Description
3.1 Market Definition and Outlook
3.2 Properties and Applications
3.3 Market Analysis
3.4 Key Players
4 Key Assumptions
5 Executive Summary
5.1 Overview
5.2 Key Drivers
5.3 Key Developments
5.4 Competitive Structure
5.5 Key Industrial Trends
6 Market Snapshot
6.1 Global
6.2 Regional
7 Opportunities and Challenges in the Market
8 Global Bone Morphogenetic Proteins Market Analysis
8.1 Key Industry Highlights
8.2 Global Bone Morphogenetic Proteins Historical Market (2018-2023)
8.3 Global Bone Morphogenetic Proteins Market Forecast (2024-2032)
8.4 Global Bone Morphogenetic Proteins Market by Type
8.4.1 Recombinant Human Bone Morphogenetic Protein (rhBMP) - 2
8.4.1.1 Historical Trend (2018-2023)
8.4.1.2 Forecast Trend (2024-2032)
8.4.2 Recombinant Human Bone Morphogenetic Protein (rhBMP) -7
8.4.2.1 Historical Trend (2018-2023)
8.4.2.2 Forecast Trend (2024-2032)
8.5 Global Bone Morphogenetic Proteins Market by Application
8.5.1 Spinal Fusion
8.5.1.1 Historical Trend (2018-2023)
8.5.1.2 Forecast Trend (2024-2032)
8.5.2 Trauma
8.5.2.1 Historical Trend (2018-2023)
8.5.2.2 Forecast Trend (2024-2032)
8.5.3 Reconstructive Surgery
8.5.3.1 Historical Trend (2018-2023)
8.5.3.2 Forecast Trend (2024-2032)
8.5.4 Oral-maxillofacial
8.5.4.1 Historical Trend (2018-2023)
8.5.4.2 Forecast Trend (2024-2032)
8.6 Global Bone Morphogenetic Proteins Market by Region
8.6.1 North America
8.6.1.1 Historical Trend (2018-2023)
8.6.1.2 Forecast Trend (2024-2032)
8.6.2 Europe
8.6.2.1 Historical Trend (2018-2023)
8.6.2.2 Forecast Trend (2024-2032)
8.6.3 Asia Pacific
8.6.3.1 Historical Trend (2018-2023)
8.6.3.2 Forecast Trend (2024-2032)
8.6.4 Latin America
8.6.4.1 Historical Trend (2018-2023)
8.6.4.2 Forecast Trend (2024-2032)
8.6.5 Middle East and Africa
8.6.5.1 Historical Trend (2018-2023)
8.6.5.2 Forecast Trend (2024-2032)
9 North America Bone Morphogenetic Proteins Market Analysis
9.1 United States of America
9.1.1 Historical Trend (2018-2023)
9.1.2 Forecast Trend (2024-2032)
9.2 Canada
9.2.1 Historical Trend (2018-2023)
9.2.2 Forecast Trend (2024-2032)
10 Europe Bone Morphogenetic Proteins Market Analysis
10.1 United Kingdom
10.1.1 Historical Trend (2018-2023)
10.1.2 Forecast Trend (2024-2032)
10.2 Germany
10.2.1 Historical Trend (2018-2023)
10.2.2 Forecast Trend (2024-2032)
10.3 France
10.3.1 Historical Trend (2018-2023)
10.3.2 Forecast Trend (2024-2032)
10.4 Italy
10.4.1 Historical Trend (2018-2023)
10.4.2 Forecast Trend (2024-2032)
10.5 Others
11 Asia Pacific Bone Morphogenetic Proteins Market Analysis
11.1 China
11.1.1 Historical Trend (2018-2023)
11.1.2 Forecast Trend (2024-2032)
11.2 Japan
11.2.1 Historical Trend (2018-2023)
11.2.2 Forecast Trend (2024-2032)
11.3 India
11.3.1 Historical Trend (2018-2023)
11.3.2 Forecast Trend (2024-2032)
11.4 ASEAN
11.4.1 Historical Trend (2018-2023)
11.4.2 Forecast Trend (2024-2032)
11.5 Australia
11.5.1 Historical Trend (2018-2023)
11.5.2 Forecast Trend (2024-2032)
15.6 Others
12 Latin America Bone Morphogenetic Proteins Market Analysis
12.1 Brazil
12.1.1 Historical Trend (2018-2023)
12.1.2 Forecast Trend (2024-2032)
12.2 Argentina
12.2.1 Historical Trend (2018-2023)
12.2.2 Forecast Trend (2024-2032)
12.3 Mexico
12.3.1 Historical Trend (2018-2023)
12.3.2 Forecast Trend (2024-2032)
12.4 Others
13 Middle East and Africa Bone Morphogenetic Proteins Market Analysis
13.1 Saudi Arabia
13.1.1 Historical Trend (2018-2023)
13.1.2 Forecast Trend (2024-2032)
13.2 United Arab Emirates
13.2.1 Historical Trend (2018-2023)
13.2.2 Forecast Trend (2024-2032)
13.3 Nigeria
13.3.1 Historical Trend (2018-2023)
13.3.2 Forecast Trend (2024-2032)
13.4 South Africa
13.4.1 Historical Trend (2018-2023)
13.4.2 Forecast Trend (2024-2032)
13.5 Others
14 Market Dynamics
14.1 SWOT Analysis
14.1.1 Strengths
14.1.2 Weaknesses
14.1.3 Opportunities
14.1.4 Threats
14.2 Porter’s Five Forces Analysis
14.2.1 Supplier’s Power
14.2.2 Buyer’s Power
14.2.3 Threat of New Entrants
14.2.4 Degree of Rivalry
14.2.5 Threat of Substitutes
14.3 Key Indicators for Demand
14.4 Key Indicators for Price
15 Competitive Landscape
15.1 Market Structure
15.2 Company Profiles
15.2.1 Thermo Fisher Scientific, Inc.
15.2.1.1 Company Overview
15.2.1.2 Product Portfolio
15.2.1.3 Demographic Reach and Achievements
15.2.1.4 Certifications
15.2.2 Medtronic plc
15.2.2.1 Company Overview
15.2.2.2 Product Portfolio
15.2.2.3 Demographic Reach and Achievements
15.2.2.4 Certifications
15.2.3 Prospec-Tany Technogene Ltd.
15.2.3.1 Company Overview
15.2.3.2 Product Portfolio
15.2.3.3 Demographic Reach and Achievements
15.2.3.4 Certifications
15.2.4 Merck KGaA
15.2.4.1 Company Overview
15.2.4.2 Product Portfolio
15.2.4.3 Demographic Reach and Achievements
15.2.4.4 Certifications
15.2.5 Others
16 Key Trends and Developments in the Market
List of Key Figures and Tables
1. Global Bone Morphogenetic Proteins Market: Key Industry Highlights, 2018 and 2032
2. Global Bone Morphogenetic Proteins Historical Market: Breakup by Type (USD Million), 2018-2023
3. Global Bone Morphogenetic Proteins Market Forecast: Breakup by Type (USD Million), 2024-2032
4. Global Bone Morphogenetic Proteins Historical Market: Breakup by Application (USD Million), 2018-2023
5. Global Bone Morphogenetic Proteins Market Forecast: Breakup by Application (USD Million), 2024-2032
6. Global Bone Morphogenetic Proteins Historical Market: Breakup by Region (USD Million), 2018-2023
7. Global Bone Morphogenetic Proteins Market Forecast: Breakup by Region (USD Million), 2024-2032
8. North America Bone Morphogenetic Proteins Historical Market: Breakup by Country (USD Million), 2018-2023
9. North America Bone Morphogenetic Proteins Market Forecast: Breakup by Country (USD Million), 2024-2032
10. Europe Bone Morphogenetic Proteins Historical Market: Breakup by Country (USD Million), 2018-2023
11. Europe Bone Morphogenetic Proteins Market Forecast: Breakup by Country (USD Million), 2024-2032
12. Asia Pacific Bone Morphogenetic Proteins Historical Market: Breakup by Country (USD Million), 2018-2023
13. Asia Pacific Bone Morphogenetic Proteins Market Forecast: Breakup by Country (USD Million), 2024-2032
14. Latin America Bone Morphogenetic Proteins Historical Market: Breakup by Country (USD Million), 2018-2023
15. Latin America Bone Morphogenetic Proteins Market Forecast: Breakup by Country (USD Million), 2024-2032
16. Middle East and Africa Bone Morphogenetic Proteins Historical Market: Breakup by Country (USD Million), 2018-2023
17. Middle East and Africa Bone Morphogenetic Proteins Market Forecast: Breakup by Country (USD Million), 2024-2032
18. Global Bone Morphogenetic Proteins Market Structure.
Key Questions Answered in the Report
The global bone morphogenetic proteins market is projected to grow at a CAGR of 2.3% between 2024 and 2032.
The major drivers of the market include the rising geriatric population, established healthcare infrastructure, high adoption of advanced technology by orthopaedic surgeons, favourable reimbursement structure, increasing awareness among surgeons for using rhBMPs, increasing healthcare spending capacity, and growing medical tourism in countries.
Increasing number of people suffering from spinal injuries and an increase in surgical rate are the key industry trends propelling the market's growth.
The major regions in the industry are North America, Latin America, the Middle East and Africa, Europe, and the Asia Pacific.
Based on type, the market is classified into recombinant human bone morphogenetic protein (rhBMP) – 2 and recombinant human bone morphogenetic protein (rhBMP) -7.
The major applications of the market are spinal fusion, trauma, reconstructive surgery, and oral-maxillofacial.
The major players in the industry are Thermo Fisher Scientific, Inc., Medtronic plc, Prospec-Tany Technogene Ltd., and Merck KGaA, among others.
Analyst Review
The global bone morphogenetic proteins market was driven by the increasing number of people suffering from spinal injuries in the historical period. Aided by the rising geriatric population and established healthcare infrastructure, the market is expected to grow at a CAGR of 2.3% in the forecast period of 2024-2032.
EMR's meticulous research methodology delves deep into the market, covering the macro and micro aspects of the industry. Based on type, the market is classified into recombinant human bone morphogenetic protein (rhBMP) – 2 and recombinant human bone morphogenetic protein (rhBMP) -7. The major applications of the market are spinal fusion, trauma, reconstructive surgery, and oral-maxillofacial. The major regional markets for bone morphogenetic proteins market are North America, Europe, the Asia Pacific, Latin America, the Middle East and Africa. The major players in the industry are Thermo Fisher Scientific, Inc., Medtronic plc, Prospec-Tany Technogene Ltd., and Merck KGaA, among others.
EMR's research methodology uses a combination of cutting-edge analytical tools and the expertise of their highly accomplished team, thus, providing their customers with market insights that are accurate, actionable and help them remain ahead of their competition.
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