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Global Bone Morphogenetic Proteins Market: By Type: Recombinant Human Bone Morphogenetic Protein (rhBMP) - 2, Recombinant Human Bone Morphogenetic Protein (rhBMP) -7; By Application; Regional Analysis; Historical Market and Forecast (2017-2027); Market Dynamics; Competitive Landscape; Industry Events and Developments

Global Bone Morphogenetic Proteins Market Outlook

The global bone morphogenetic proteins market is expected to grow at a CAGR of 2.3% during the period 2022-2027. North America, Europe and Asia are likely to be key markets.

 

Global Market Likely to be Driven by Uses in a Variety of Processes During the Formation and Maintenance of Organs such as Bone, Cartilage, and Muscle, Among Others

Bone morphogenetic proteins (BMPs) is the common name of a family of proteins, recognized first in extracts of demineralized bone that were capable of encouraging bone formation at ectopic sites. Bone morphogenetic proteins are present in small amounts in bone material (nearly 1 microgram/kg dry weight of bone). Generally, the term bone morphogenetic proteins describes a certain function of these proteins, which have been implicated also in many other processes. Bone morphogenetic proteins such as BMP2, BMP4, and BMP7 also play a role in the specification of hematopoietic tissue from the mesodermal germ layer.

Bone morphogenetic proteins belong to the family of transforming growth factors. Presently, nearly twenty different bone morphogenetic proteins have been identified, all with different degrees of tissue stimulating properties. Bone morphogenetic proteins play important roles in a broad range of processes during the formation and maintenance of organs such as bone, cartilage, muscle, kidney, and blood vessels. As deregulation of the bone morphogenetic protein activity at multiple steps in signal transduction is associated with several human diseases, therapeutic use of activators and inhibitors of bone morphogenetic proteins signaling would provide potential avenues for the treatment of human ailments caused by hypo- and hyperactivation of bone morphogenetic proteins signals.

 

Applications of Bone Morphogenetic Proteins in Domains Such as Dentistry, Orthopaedics, Sports Likely to Boost Market Growth

Bone tissue is a mineralized structure with complex metabolism, and given its mechanical functions, its structure must be adapted to bone function. Bone morphogenetic proteins group stimulates the formation of bone and cartilage and influences several non-osteogenic processes. Due to their osteogenic effect, bone morphogenetic proteins are employed in several areas of medicine, including dentistry, orthopaedics, sport and rehabilitation. Such applications are expected to drive the global bone morphogenetic proteins market. Recombinant human bone morphogenetic proteins (rhBMPs) are administered to the bone grafting site through surgery. Bone morphogenetic proteins stimulate bone growth naturally in the human body. These proteins that exist in the body can be produced, concentrated and placed in the area of the spine for spinal fusion to occur.  More importantly, these can generate fusion without the need for any use of the patient’s own bone.

Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGFβ superfamily. It plays an important role in embryonic dorsalventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. Bone morphogenetic protein 2 is an effective osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. Bone morphogenetic protein 2 also plays a key role in cardiac morphogenesis and is expressed in multiple tissues including lung, spleen, brain, liver, prostate ovary and small intestine.

 

Advanced Solutions Likely to Stimulate Market Growth

InfuseTM Bone Graft is a premium product for autograft replacement due to its high osteoinductivity. Infuse bone graft is recombinant human bone morphogenetic protein-2 (rhBMP-2) applied to an absorbable collagen sponge carrier (ACS). One of the functions of the protein is to inspire natural bone formation. INFUSE® Bone Graft is a revolutionary bone graft that helps inspire natural bone formation and remodelling and circumvents the need to harvest bone from other parts of a patient’s body. Infuse has been on the market since 2002 and used in over 1 million patients across the world. Such solutions are expected to drive growth of the global bone morphogenetic proteins market. Infuse is indicated for certain spinal fusion procedures in skeletally mature patients with degenerative disc disease (DDD) from L2 to S1, as well as for treating certain acute, open tibial shaft fractures. Infuse is also approved for certain oral-maxillofacial procedures.

 

Market Segmentation

By type, the market is segmented into:

  • Recombinant Human Bone Morphogenetic Protein (rhBMP) - 2
  • Recombinant Human Bone Morphogenetic Protein (rhBMP) -7

By application, the market is divided into:

  • Spinal Fusion
  • Trauma 
  • Reconstructive Surgery
  • Oral-maxillofacial

By region, the market is classified into:

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa

 

Key Industry Players in the Market

The report presents a detailed analysis of the following key players in the global bone morphogenetic proteins market, looking into their capacity, and latest developments like capacity expansions, plant turnarounds, and mergers and acquisitions:

  • Thermo Fisher Scientific, Inc.
  • Medtronic plc
  • Prospec-Tany Technogene Ltd.
  • Merck KGaA
  • Others

The EMR report gives an in-depth insight into the industry by providing a SWOT analysis as well as an analysis of Porter’s Five Forces model.

 

Key Highlights of the Report

REPORT FEATURES DETAILS
Base Year 2021
Historical Period 2017-2021
Forecast Period 2022-2027
Scope of the Report

Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:

  • Type
  • Application
  • Region
Breakup by Type
  • Recombinant Human Bone Morphogenetic Protein (rhBMP) - 2
  • Recombinant Human Bone Morphogenetic Protein (rhBMP) -7
Breakup by Application
  • Spinal Fusion
  • Trauma 
  • Reconstructive Surgery
  • Oral-maxillofacial
Breakup by Region
  • North America
    • United States of America 
    • Canada
  • Europe
    • United Kingdom
    • Germany
    • France
    • Italy
    • Others
  • Asia Pacific
    • China
    • Japan
    • India
    • ASEAN
    • Australia
    • Others
  • Latin America
    • Brazil
    • Argentina
    • Mexico
    • Others
  • Middle East and Africa
    • Saudi Arabia
    • United Arab Emirates
    • Nigeria
    • South Africa
    • Others
Market Dynamics
  • SWOT
  • Porter's Five Forces
  • Key Indicators for Demand
  • Key Indicators for Price
Competitive Landscape
  • Market Structure
  • Company Profiles
    • Company Overview
    • Product Portfolio
    • Demographic Reach and Achievements
    • Certifications
Companies Covered
  • Thermo Fisher Scientific, Inc.
  • Medtronic plc
  • Prospec-Tany Technogene Ltd.
  • Merck KGaA
  • Others
Report Price and Purchase Option Explore our purchase options that are best suited to your resources and industry needs.
Delivery Format Delivered as an attached PDF and Excel through email, with an option of receiving an editable PPT, according to the purchase option.

 

*We at Expert Market Research always strive to give you the latest information. The numbers in the article are only indicative and may be different from the actual report.

1    Preface 
2    Report Coverage – Key Segmentation and Scope
3    Report Description

    3.1    Market Definition and Outlook
    3.2    Properties and Applications
    3.3    Market Analysis
    3.4    Key Players
4    Key Assumptions   
5    Executive Summary

    5.1    Overview
    5.2    Key Drivers
    5.3    Key Developments  
    5.4    Competitive Structure
    5.5    Key Industrial Trends
6    Market Snapshot
    6.1    Global
    6.2    Regional 
7    Industry Opportunities and Challenges  
8    Global Bone Morphogenetic Proteins Market Analysis

    8.1    Key Industry Highlights
    8.2    Global Bone Morphogenetic Proteins Historical Market (2017-2021) 
    8.3    Global Bone Morphogenetic Proteins Market Forecast (2022-2027)
    8.4    Global Bone Morphogenetic Proteins Market by Type
        8.4.1    Recombinant Human Bone Morphogenetic Protein (rhBMP) - 2
            8.4.1.1    Market Share
            8.4.1.2    Historical Trend (2017-2021)
            8.4.1.3    Forecast Trend (2022-2027)
        8.4.2    Recombinant Human Bone Morphogenetic Protein (rhBMP) -7
            8.4.2.1    Market Share
            8.4.2.2    Historical Trend (2017-2021)
            8.4.2.3    Forecast Trend (2022-2027)
    8.5    Global Bone Morphogenetic Proteins Market by Application
        8.5.1    Spinal Fusion
            8.5.1.1    Market Share
            8.5.1.2    Historical Trend (2017-2021)
            8.5.1.3    Forecast Trend (2022-2027)
        8.5.2    Trauma 
            8.5.2.1    Market Share
            8.5.2.2    Historical Trend (2017-2021)
            8.5.2.3    Forecast Trend (2022-2027)
        8.5.3    Reconstructive Surgery
            8.5.3.1    Market Share
            8.5.3.2    Historical Trend (2017-2021)
            8.5.3.3    Forecast Trend (2022-2027)
        8.5.4    Oral-maxillofacial
            8.5.4.1    Market Share
            8.5.4.2    Historical Trend (2017-2021)
            8.5.4.3    Forecast Trend (2022-2027)
    8.6    Global Bone Morphogenetic Proteins Market by Region
        8.6.1    Market Share
            8.6.1.1    North America
            8.6.1.2    Europe
            8.6.1.3    Asia Pacific
            8.6.1.4    Latin America
            8.6.1.5    Middle East and Africa
9    Regional Analysis
    9.1    North America
        9.1.1    Historical Trend (2017-2021)
        9.1.2    Forecast Trend (2022-2027)
        9.1.3    Breakup by Country
            9.1.3.1    United States of America 
            9.1.3.2    Canada
    9.2    Europe 
        9.2.1    Historical Trend (2017-2021)
        9.2.2    Forecast Trend (2022-2027)
        9.2.3    Breakup by Country
            9.2.3.1    United Kingdom
            9.2.3.2    Germany
            9.2.3.3    France
            9.2.3.4    Italy
            9.2.3.5    Others
    9.3    Asia Pacific
        9.3.1    Historical Trend (2017-2021)
        9.3.2    Forecast Trend (2022-2027)
        9.3.3    Breakup by Country
            9.3.3.1    China
            9.3.3.2    Japan
            9.3.3.3    India
            9.3.3.4    ASEAN
            9.3.3.5    Australia
            9.3.3.6    Others
    9.4    Latin America
        9.4.1    Historical Trend (2017-2021)
        9.4.2    Forecast Trend (2022-2027)
        9.4.3    Breakup by Country
            9.4.3.1    Brazil
            9.4.3.2    Argentina
            9.4.3.3    Mexico
            9.4.3.4    Others
    9.5    Middle East and Africa
        9.5.1    Historical Trend (2017-2021)
        9.5.2    Forecast Trend (2022-2027)
        9.5.3    Breakup by Country
            9.5.3.1    Saudi Arabia
            9.5.3.2    United Arab Emirates
            9.5.3.3    Nigeria
            9.5.3.4    South Africa
            9.5.3.5    Others
10    Market Dynamics
    10.1    SWOT Analysis
        10.1.1    Strengths
        10.1.2    Weaknesses
        10.1.3    Opportunities
        10.1.4    Threats
    10.2    Porter’s Five Forces Analysis
        10.2.1    Supplier’s Power
        10.2.2    Buyer’s Power
        10.2.3    Threat of New Entrants
        10.2.4    Degree of Rivalry
        10.2.5    Threat of Substitutes
    10.3    Key Indicators for Demand
    10.4    Key Indicators for Price
11    Competitive Landscape
    11.1    Market Structure
    11.2    Company Profiles
        11.2.1    Thermo Fisher Scientific, Inc.
            11.2.1.1    Company Overview
            11.2.1.2    Product Portfolio
            11.2.1.3    Demographic Reach and Achievements
            11.2.1.4    Certifications
        11.2.2    Medtronic plc
            11.2.2.1    Company Overview
            11.2.2.2    Product Portfolio
            11.2.2.3    Demographic Reach and Achievements
            11.2.2.4    Certifications
        11.2.3    Prospec-Tany Technogene Ltd.
            11.2.3.1    Company Overview
            11.2.3.2    Product Portfolio
            11.2.3.3    Demographic Reach and Achievements
            11.2.3.4    Certifications
        11.2.4    Merck KGaA
            11.2.4.1    Company Overview
            11.2.4.2    Product Portfolio
            11.2.4.3    Demographic Reach and Achievements
            11.2.4.4    Certifications
        11.2.5    Others
12    Industry Events and Developments

 

List of Key Figures and Tables

1.    Global Bone Morphogenetic Proteins Market: Key Industry Highlights, 2017 and 2027
2.    Global Bone Morphogenetic Proteins Historical Market: Breakup by Type (USD Million), 2017-2021
3.    Global Bone Morphogenetic Proteins Market Forecast: Breakup by Type (USD Million), 2022-2027
4.    Global Bone Morphogenetic Proteins Historical Market: Breakup by Application (USD Million), 2017-2021
5.    Global Bone Morphogenetic Proteins Market Forecast: Breakup by Application (USD Million), 2022-2027
6.    Global Bone Morphogenetic Proteins Historical Market: Breakup by Region (USD Million), 2017-2021
7.    Global Bone Morphogenetic Proteins Market Forecast: Breakup by Region (USD Million), 2022-2027
8.    North America Bone Morphogenetic Proteins Historical Market: Breakup by Country (USD Million), 2017-2021
9.    North America Bone Morphogenetic Proteins Market Forecast: Breakup by Country (USD Million), 2022-2027
10.    Europe Bone Morphogenetic Proteins Historical Market: Breakup by Country (USD Million), 2017-2021
11.    Europe Bone Morphogenetic Proteins Market Forecast: Breakup by Country (USD Million), 2022-2027
12.    Asia Pacific Bone Morphogenetic Proteins Historical Market: Breakup by Country (USD Million), 2017-2021
13.    Asia Pacific Bone Morphogenetic Proteins Market Forecast: Breakup by Country (USD Million), 2022-2027
14.    Latin America Bone Morphogenetic Proteins Historical Market: Breakup by Country (USD Million), 2017-2021
15.    Latin America Bone Morphogenetic Proteins Market Forecast: Breakup by Country (USD Million), 2022-2027
16.    Middle East and Africa Bone Morphogenetic Proteins Historical Market: Breakup by Country (USD Million), 2017-2021
17.    Middle East and Africa Bone Morphogenetic Proteins Market Forecast: Breakup by Country (USD Million), 2022-2027
18.    Global Bone Morphogenetic Proteins Market Structure.

Key Questions Answered in the Report

The global bone morphogenetic proteins market is projected to grow at a CAGR of 2.3% between 2022 and 2027.

The major drivers of the market include the rising geriatric population, established healthcare infrastructure, high adoption of advanced technology by orthopaedic surgeons, favourable reimbursement structure, increasing awareness among surgeons for using rhBMPs, increasing healthcare spending capacity, and growing medical tourism in countries.

Increasing number of people suffering from spinal injuries and an increase in surgical rate are the key industry trends propelling the market's growth.

The major regions in the industry are North America, Latin America, the Middle East and Africa, Europe, and the Asia Pacific.

Based on type, the market is classified into recombinant human bone morphogenetic protein (rhBMP) – 2 and recombinant human bone morphogenetic protein (rhBMP) -7.

The major applications of the market are spinal fusion, trauma, reconstructive surgery, and oral-maxillofacial.

The major players in the industry are Thermo Fisher Scientific, Inc., Medtronic plc, Prospec-Tany Technogene Ltd., and Merck KGaA, among others.

Analyst Review

The global bone morphogenetic proteins market was driven by the increasing number of people suffering from spinal injuries in the historical period. Aided by the rising geriatric population and established healthcare infrastructure, the market is expected to grow at a CAGR of 2.3% in the forecast period of 2022-2027.

EMR's meticulous research methodology delves deep into the market, covering the macro and micro aspects of the industry. Based on type, the market is classified into recombinant human bone morphogenetic protein (rhBMP) – 2 and recombinant human bone morphogenetic protein (rhBMP) -7. The major applications of the market are spinal fusion, trauma, reconstructive surgery, and oral-maxillofacial. The major regional markets for bone morphogenetic proteins market are North America, Europe, the Asia Pacific, Latin America, the Middle East and Africa. The major players in the industry are Thermo Fisher Scientific, Inc., Medtronic plc, Prospec-Tany Technogene Ltd., and Merck KGaA, among others.

EMR's research methodology uses a combination of cutting-edge analytical tools and the expertise of their highly accomplished team, thus, providing their customers with market insights that are accurate, actionable and help them remain ahead of their competition.

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