The global ePharmacy market was valued at USD 106.41 Billion in 2025 and is expected to grow at a CAGR of 14.20%, reaching USD 401.46 Billion by 2035. The market growth is driven by the rising internet penetration and demand for doorstep delivery of medicines across the globe.
Base Year
Historical Period
Forecast Period
Mobile-first platforms are expected to dominate, driven by smartphone penetration and personalized digital engagement in prescription management.
Major market trends include strategic retail-pharmacy partnerships, that will boost patient loyalty and expand digital access to essential and specialty medications.
The market growth is driven by rising AI-driven personalization in ePharmacy platforms to increase adherence rates and drive innovation across chronic care management pathways.
Compound Annual Growth Rate
14.2%
Value in USD Billion
2026-2035
*this image is indicative*
The market involves the digital purchase and delivery of prescription and over-the-counter medications through mobile apps and websites. In May 2024, the U.S. Food and Drug Administration emphasized the increasing role of digital health in prescription adherence and accessibility, especially post-COVID. Growing internet penetration, telemedicine integration, and consumer preference for doorstep delivery have driven platform adoption globally. The sector plays a crucial role in expanding pharmaceutical access, reducing pharmacy wait times, and enabling chronic disease management through personalized refill schedules, making it an essential pillar of modern healthcare infrastructure. The market is anticipated to grow at a CAGR of 14.20% during the forecast period of 2026-2035.
Regulatory Clarity and Telepharmacy Policies Fuel Market Expansion
Clearer policy frameworks are supporting the rapid adoption of ePharmacy services, especially through telehealth integration. For instance, the DEA and HHS jointly extended temporary telemedicine exceptions in January 2025, allowing physicians to prescribe controlled substances without in-person evaluations. This ensures uninterrupted access for patients managing chronic illnesses or mental health conditions. These regulatory adaptations reduce logistical barriers, expand coverage in remote regions, and enhance care continuity. As telepharmacy and ePrescription models mature, the global market benefits from accelerated growth and deeper integration within digital healthcare ecosystems.
Major market trends include rising integration of artificial intelligence in pharmacy operations and ease in regulatory oversight.
AI Enabled Automation Accelerates Pharmacy Operations and Patient Care
The integration of AI and automation is reshaping pharmacy operations by enhancing efficiency, safety, and patient engagement. For instance, a May 2025 report by Drug Topics highlighted that AI-powered systems have reduced prescription processing times from 24 hours to just 20 minutes in select clinical environments. These technologies streamline back-end logistics, reduce human error, and free up pharmacists to focus on clinical counselling and care. As a result, digital pharmacy platforms become faster, more reliable, and patient-centric, helping them compete effectively with traditional pharmacies.
Regulatory Oversight Strengthens Online Pharmacy Trust and Integrity
Increased regulatory scrutiny is driving safety and transparency in the online pharmacy landscape. For instance, a 2024 review published by East Street Pharmacy detailed how new legislation has introduced stringent prescription verification, mandatory licensing, and tighter data protection rules for digital pharmacies. These measures ensure that only verified and compliant platforms operate, protecting consumers from counterfeit drugs and unsafe practices. By enforcing these protocols, regulatory bodies enhance public confidence and enable sustainable growth of the ePharmacy sector across diverse healthcare markets.
Mobile Application to Hold a Significant Share of the Operating Platform Segmentation
The mobile application segment is projected to hold the largest market share due to its superior convenience, real-time interactivity, and on-the-go medication management. According to Pew Research Center, as of mid‑2024, 91% of the U.S. adults owned a smartphone, with 90% consistently maintaining ownership over recent years, demonstrating sustained mobile engagement. Mobile apps enable features like barcode scanning, push reminders, telehealth integration, and instant payments, making them ideal for prescription refills and chronic care. Website platforms, while still relevant, lack this seamless, user-centric immediacy, positioning mobile apps as the dominant operating platform.
North America is poised to dominate the global market, holding over 41% of the share in the historical period due to its mature telehealth infrastructure, favorable reimbursement frameworks, and widespread adoption of electronic prescriptions. Europe ranks second, supported by stringent data protection laws like GDPR and strong cross-border digital prescription networks. Both regions benefit from high consumer trust and regulatory clarity, making them central to ePharmacy growth. In comparison, Asia Pacific and Latin America are emerging markets with infrastructural gaps and regulatory limitations slowing adoption.
The key features of the market report comprise grants analysis, funding and investment analysis, and strategic initiatives by the leading players. The major companies in the market are as follows:
The company is headquartered in Chennai and was founded in 2015. It operates India’s largest ePharmacy and serves over 5.7 million users across 670+ cities, offering 70,000 prescription and wellness products. Its acquisition by Reliance Retail in 2020 expanded its omni-channel model, integrating online and over 2,000 physical pharmacies in 2023, positioning it as a dominant player in ePharmacy infrastructure and reach.
Founded in 1883 and headquartered in Cincinnati, Kroger operates over 2,200 in-store pharmacies integrated within its supermarket network. In 2024, Kroger’s digital sales surpassed USD 13 billion, growing 11% year-over-year, fueled by pharmacy and e-commerce synergies, with digital households spending nearly three times more than non-digital ones. In March 2025, Kroger launched a dedicated eCommerce business unit led by its Chief Digital Officer to accelerate online growth and streamline customer experience. These initiatives reinforce Kroger’s role as a digitally enabled pharmacy leader.
Headquartered in Bentonville and founded in 1962, scaled its online pharmacy in 2023 by integrating Walmart Health virtual consultations with ePharmacy services. It launched same-day prescription delivery in October 2024 across 1,000 U.S. zip codes and added telehealth-enabled refills via its mobile app, reinforcing direct-to-patient reach within existing retail and digital infrastructure.
Headquartered in Pittsburgh and established in 1931, Giant Eagle operates over 200 pharmacies across Pennsylvania, Ohio, West Virginia, Maryland, and Indiana as part of its broader food and fuel retail presence. In April 2025, it partnered with EmpiRx Health to implement a pharmacist-led PBM model for its employees and launch AllyRx: the first national pharmacy care network tailored to grocery-retail settings. This collaboration integrates AI-enabled clinical services, opens formulary access, and links pharmacy benefits to grocery loyalty, positioning Giant Eagle as an industry innovator addressing drug costs and patient outcomes
*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*
Other players in the market include Cigna Corporation (Express Scripts Holdings), CVS Health Corporation, Optum Rx, Inc., Rowlands Pharmacy, Amazon.com, and Apollo Pharmacy.
“ePharmacy Market Report and Forecast 2026-2035” offers a detailed analysis of the market based on the following segments:
Market Breakup by Type
Market Breakup by Operating Platform
Market Breakup by Application Areas
Market Breakup by Region
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*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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| REPORT FEATURES | DETAILS |
| Base Year | 2025 |
| Historical Period | 2019-2025 |
| Forecast Period | 2026-2035 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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| Breakup by Type |
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| Breakup by Operating Platform |
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| Breakup by Application Areas |
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| Breakup by Region |
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| Market Dynamics |
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| Supplier Landscape |
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