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Global Iron Deficiency Anaemia Treatment Market Size, Share, Demand, Research: By Drug Type: Ferrous Sulphate, Ferrous Gluconate, Ferrous Fumarate, Ferric Hydroxide, Others; By Route of Administration; By Treatment Channel; Regional Analysis; Current Scenario Evaluation; Challenges and Unmet Needs; Supplier Landscape; 2022-2030

Global Iron Deficiency Anaemia Treatment Market Outlook

The growth of the global iron deficiency anaemia treatment market is driven by the rising prevalence of iron deficiency anaemia, which was close to 1.8 billion in 2021. The prevalence of iron deficiency anaemia is likely to grow at a CAGR of 4% in the forecast period of 2022-2030, which would add further growth to the treatment market.

 

Key Company News

In June 2021, a generic version of Feraheme was launched by Sandoz to treat patients with iron deficiency anaemia with Ferumoxytol, a high-dose intravenous iron supplement. The generic version of ferrahem (ferumoxytol injection), produced by AMAG Pharmaceuticals was approved to treat IDA in adults suffering from oral iron intolerance or chronic kidney disease, who do not respond well to oral iron.

 

In January 2020, the U.S. Food and Drug Administration (FDA) approved ferric derisomaltose injection, manufactured by PHARMACOSMOS A/S, for treating chronic kidney disease patients who cannot tolerate or are irresponsive to oral iron, or who are not dependent on haemodialysis for treating iron deficiency anaemia.

 

Introduction

A condition called anaemia occurs when the red blood cells (RBCs) or the haemoglobin concentration is insufficient. The body's tissues need haemoglobin to carry oxygen, and when a person has too few red blood cells, is malformed, or has no haemoglobin, then blood is unable to carry oxygen.

 

The main symptom of anaemia is a low number of red blood cells, which can cause paleness, fatigue, and weakness. The subtypes are classified according to the chronicity, size, and aetiology of the RBCs.

 

The loss of blood and decrease in red blood cell production can lead to anaemia due to an iron deficiency or an increase in red blood cell destruction by haemolysis. The main cause of anaemia is iron deficiency.

 

Iron levels can be used to categorize IDAs into mild, moderate, and severe categories. Symptoms and signs of mild to moderate disease are usually absent. Symptoms related to the severe form include fatigue, shortness of breath, or chest pain.

 

IDA (iron deficiency anaemia) is characterized by iron deficiency. This may be mainly due to low iron intake. IDA can also be caused by blood loss, an inability to absorb iron, and other health issues.

 

IDA is usually diagnosed by a physical exam and blood tests. In order to determine if the body has enough normal blood cells, iron and ferritin, a complete blood count is appropriate.

 

Treatment begins once IDA is diagnosed. Patients' characteristics and disease severity determine the treatment procedure. Increased consumption of iron supplements is the most common and the first prescribed treatment by doctors.

 

The supplements can be taken orally (Auryxia, Accrufer, and OTC) or intravenously (Venofer, Feraheme, and Monofer, among others). A blood transfusion or surgery may be needed in extreme/serious cases.

 

According to the global iron deficiency anaemia treatment market research report, the market can be categorised into the following segments:

 

Market Breakup by Drug Type

  • Ferrous Sulphate
  • Ferrous Gluconate
  • Ferrous Fumarate
  • Ferric Hydroxide
  • Sodium Ferric Gluconate
  • Iron Carbohydrates
  • Others

 

Market Breakup by Route of Administration

  • Tablets
  • Capsules
  • Liquids

 

Market Breakup by Treatment Channel

  • Public
  • Private

 

Market Breakup by Region

  • North America
    • United States of America
    • Canada
  • Europe
    • United Kingdom
    • Germany
    • France
    • Italy
    • Others
  • Asia Pacific
    • China
    • Japan
    • India
    • ASEAN
    • Australia
    • Others
  • Latin America
    • Brazil
    • Argentina
    • Mexico
    • Others
  • Middle East and Africa
    • Saudi Arabia
    • United Arab Emirates
    • Nigeria
    • South Africa
    • Others

 

Increasing Prevalence, Rising Investment for Healthcare Infrastructure, Increasing Research and Development Activities to be the Key Market Trends

The growth of the iron deficiency anaemia treatment market is primarily driven by the rising prevalence of the disease as well as chronic kidney diseases. The market is also propelled by other factors such as the rapidly developing healthcare infrastructure.

 

The growth of the market can also be attributed to the rising awareness about the disease as well as its treatment by the public and private organisations.


Rising disposable incomes of the populations and the increased risk of blood dilution will also increase the demand for iron deficiency anaemia treatments. As the population ages and people lead sedentary lifestyles, the market is expected to grow further in the coming years.

 

The market is also witnessing rapid growth due to the increasing research and development activities. As a result, the market is expected to grow significantly over the next few years.

 

In addition, the approval and launch of more drugs is expected to accelerate the market growth. Rising investment in advanced technology and growth in emerging markets will act as lucrative opportunities for the growth of the iron deficiency anaemia treatment market in the coming years.

 

Factors like High Costs of the Treatment and Lack of Professionals are Restricting the Growth of the Market

The high cost of the treatment will hamper the growth of the market as most of the patients are unable to afford it. In the developing countries, iron deficiency anaemia treatment market will be challenged by a lack of skilled professionals and medical infrastructure.

 

North America Dominates the Global Iron Deficiency Anaemia Treatment Market

North America dominates the iron deficiency anaemia treatment market due to the region's well-established healthcare infrastructure. The key players will be increasingly interested in new technologies, which will add further growth to the market.

 

It is expected that the Asia Pacific region will also witness significant growth over the forecast period due to population growth and rise in healthcare spending.

 

Therapeutic Landscape

It is common for IDA patients to be prescribed oral iron supplements in pill, tablet, or syrup form in the early stages. There are several over the counter (OTC) iron remedies available in the market. The gastrointestinal side effects of oral iron reduce patient compliance. It is recommended to use intravenous iron if the patient no longer responds to these drugs or if the drugs are not working as effectively as before.

 

IDA Approved Drugs

Auryxia (Riona/ KRX-0502/Ferric Citrate): Akebia Therapeutics

Due to its unique chemical properties and mechanism of action, Auryxia is a calcium-free iron-based compound that doubles as a treatment for CKD patients. This drug contains a small molecule called ferric citrate as its active ingredient.

 

Immediately following its approval by the US Food and Drug Administration (FDA) in September 2014, the drug was marketed in the United States as a phosphate binder for hyperphosphatemia. It was approved by the FDA in 2017 for IDA, a second indication for treatment of adult patients.

 

Feraccru/Accrufer (Ferric Maltol/ ST10): Shield Therapeutics

Feraccru/Accrufer provides an alternative to intravenous iron therapy for patients who are intolerant to oral iron supplements.

 

Feraheme/Rienso (Ferumoxytol): AMAG Pharmaceuticals

For intravenous use, Feraheme contains ferumoxytol as a replacement for iron. It is an inorganic magnetite (superparamagnetic iron oxide) coated with polyglucose sorbitol carboxymethyl ether.

 

Clinical Trials

 

IDA Emerging Drugs

MPB-1514 (IOP Injection): MegaPro Biomedical

MegaPro Biomedical is developing MPB-1514/IOP injection for the treatment of IDA that is sugar-free. It is extremely safe as it follows doctor's prescription. The PEG coating would allow high-dose administration and lead to an increase in red blood cells without frequent injections. Currently, the drug is the only sugar-free injection in development.

 

IDAX (IHAT-02): Nemysis

Nemysis (IHAT-02/IDAX) is the first ferritin-mimic product that uses a tartrate salt to insulate the ferrihydrite nanocore of adipate-buffered ferritin. IHAT is well absorbed and maintains healthy gut bacteria. IHAT has been shown to be efficiently absorbed by humans and correct markers of iron deficiency without causing gastrointestinal side effects. As a result of this product, iron can be absorbed in the intestine in a manner similar to what happens naturally.

 

Competitive Landscape

The report gives an in-depth analysis of the key players involved in the global iron deficiency anaemia treatment market, sponsors manufacturing the drugs, and putting them through trials to get FDA approvals. The companies included in the market are as follows:

 

  • Amgen Inc.
  • Hoffmann-La Roche Ltd
  • Novartis AG
  • Pfizer Inc
  • Janssen Pharmaceuticals, Inc.
  • AMAG Pharmaceuticals
  • Teva Pharmaceutical Industries Ltd.

 

Key Highlights of the Report

REPORT FEATURES DETAILS
Base Year 2021
Historical Period 2015-2021
Forecast Period 2022-2030
Scope of the Report

Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:

  • Drug Type
  • Route of Administration
  • Treatment Channel
  • Region
Breakup by Drug Type
  • Ferrous Sulphate
  • Ferrous Gluconate
  • Ferrous Fumarate
  • Ferric Hydroxide
  • Sodium Ferric Gluconate
  • Iron Carbohydrates
  • Others
Breakup by Route of Administration
  • Tablets
  • Capsules
  • Liquids
Breakup by Treatment Channel
  • Public
  • Private
Breakup by Region
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa
Market Dynamics
  • SWOT
  • Porter's Five Forces
  • Key Indicators for Demand
  • Key Indicators for Price
Competitive Landscape
  • Market Structure
  • Company Profiles
    • Company Overview
    • Product Portfolio
    • Demographic Reach and Achievements
    • Certifications
Companies Covered
  • Amgen Inc.
  • Hoffmann-La Roche Ltd
  • Novartis AG
  • Pfizer Inc
  • Janssen Pharmaceuticals, Inc.
  • AMAG Pharmaceuticals
  • Teva Pharmaceutical Industries Ltd.

 

*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.

1    Preface
    1.1    Objectives of the Study
        1.1.1     Research Objectives
        1.1.2     Key Findings of the Report
    1.2    Limitations of the Study and Scope for Future Research
2    Research Methodology
3    Executive Summary
4    Global Iron Deficiency Anaemia Treatment Market Overview

    4.1    Guidelines and Stages
    4.2    Pathophysiology
    4.3    Screening and Diagnosis
    4.4    Treatment Pathway 
5    Patient Profile
    5.1    Patient Profile Model
    5.2    Patient Psychology and Emotional Impact Factors
    5.3    Risk Assessment and Treatment Success Rate
6    Global Iron Deficiency Anaemia Treatment Market
    6.1    Global Iron Deficiency Anaemia Treatment Market Overview
    6.2    Global Iron Deficiency Anaemia Treatment Market Analysis 
        6.2.1     Market Overview
            6.2.1.1    Global Iron Deficiency Anaemia Treatment Historical Market Value (2015-2021) 
            6.2.1.2    Global Iron Deficiency Anaemia Treatment Forecast Market Value (2022-2030)
    6.3    Global Iron Deficiency Anaemia Treatment Market by Drug Type
        6.3.1     Market Overview
            6.3.1.1    Ferrous Sulphate
            6.3.1.2    Ferrous Gluconate
            6.3.1.3    Ferrous Fumarate 
            6.3.1.4    Ferric Hydroxide
            6.3.1.5    Sodium Ferric Gluconate
            6.3.1.6    Iron Carbohydrates
            6.3.1.7    Others
    6.4    Global Iron Deficiency Anaemia Treatment Market by Route of Administration
        6.4.1     Market Overview
            6.4.1.1    Tablets
            6.4.1.2    Capsules
            6.4.1.3    Liquids
    6.5    Global Iron Deficiency Anaemia Treatment Market by Treatment Channel
        6.5.1    Market Overview
            6.5.1.1     Public
            6.5.1.2     Private
    6.6    Global Iron Deficiency Anaemia Treatment Market by Region
        6.6.1     Market Overview
            6.6.1.1    North America
            6.6.1.2    Europe 
            6.6.1.3    Asia Pacific
            6.6.1.4    Latin America 
            6.6.1.5    Middle East and Africa
    6.7    North America
        6.7.1    Historical Trend (2015-2021)
        6.7.2    Forecast Trend (2022-2030)
        6.7.3    Break Up by Country
            6.7.3.1    United States of America
            6.7.3.2    Canada
    6.8    Europe
        6.8.1    Historical Trend (2015-2021)
        6.8.2    Forecast Trend (2022-2030)
        6.8.3    Break Up by Country
            6.8.3.1    Germany
            6.8.3.2    France
            6.8.3.3    Italy
            6.8.3.4    Russia 
            6.8.3.5    Spain
            6.8.3.6    Netherlands
            6.8.3.7    Others
    6.9    Asia Pacific
        6.9.1    Historical Trend (2015-2021)
        6.9.2    Forecast Trend (2022-2030)
        6.9.3    Break Up by Country
            6.9.3.1    China
            6.9.3.2    Japan
            6.9.3.3    India
            6.9.3.4    South Korea
            6.9.3.5    Australia
            6.9.3.6    Indonesia
            6.9.3.7    Others
    6.10    Middle East and Africa
        6.10.1    Historical Trend (2015-2021)
        6.10.2    Forecast Trend (2022-2030)
        6.10.3    Break Up by Country
            6.10.3.1    Saudi Arabia
            6.10.3.2    Egypt
            6.10.3.3    South Africa
            6.10.3.4    Others
    6.11    Latin America
        6.11.1    Historical Trend (2015-2021)
        6.11.2    Forecast Trend (2022-2030)
        6.11.3    Break Up by Country
            6.11.3.1    Mexico
            6.11.3.2    Brazil
            6.11.3.3    Colombia
            6.11.3.4    Argentina
            6.11.3.5    Others
7    Current Scenario Evaluation
    7.1    Emerging Therapies and Clinical Trials Synopsis
    7.2    Patent Landscape and Impact
    7.3    Cost of Treatment
    7.4    Others
8    Challenges and Unmet Needs
    8.1    Treatment Pathway Challenges
    8.2    Compliance and Drop-Out Analysis
    8.3    Awareness and Prevention Gaps
9    Global Iron Deficiency Anaemia Treatment Industry Dynamics
    9.1    Industry Drivers and Constraints
    9.2    SWOT Analysis
    9.3    Porter’s Five Forces
    9.4    Key Demand Indicators
    9.5    Key Price Indicators
    9.6    Industry Events, Initiatives, and Trends 
    9.7    Value Chain
10    Supplier Landscape
    10.1    Amgen Inc.
        10.1.1    Company Overview
        10.1.2    Product Portfolio
        10.1.3    Demographic Reach and Achievements
        10.1.4    Mergers and Acquisitions
        10.1.5    Certifications
    10.2    Hoffmann-La Roche Ltd
        10.2.1    Company Overview
        10.2.2    Product Portfolio
        10.2.3    Demographic Reach and Achievements
        10.2.4    Mergers and Acquisitions
        10.2.5    Certifications
    10.3    Novartis AG
        10.3.1    Company Overview
        10.3.2    Product Portfolio
        10.3.3    Demographic Reach and Achievements
        10.3.4    Mergers and Acquisitions
        10.3.5    Certifications
    10.4    Pfizer Inc
        10.4.1    Company Overview
        10.4.2    Product Portfolio
        10.4.3    Demographic Reach and Achievements
        10.4.4    Mergers and Acquisitions
        10.4.5    Certifications
    10.5    Janssen Pharmaceuticals, Inc.
        10.5.1    Company Overview
        10.5.2    Product Portfolio
        10.5.3    Demographic Reach and Achievements
        10.5.4    Mergers and Acquisitions
        10.5.5    Certifications
    10.6    AMAG Pharmaceuticals
        10.6.1    Company Overview
        10.6.2    Product Portfolio
        10.6.3    Demographic Reach and Achievements
        10.6.4    Mergers and Acquisitions
        10.6.5    Certifications
    10.7    Teva Pharmaceutical Industries Ltd.
        10.7.1    Company Overview
        10.7.2    Product Portfolio
        10.7.3    Demographic Reach and Achievements
        10.7.4    Mergers and Acquisitions
        10.7.5    Certifications
11    Recommendations and Discussion
12    Global Iron Deficiency Anaemia Treatment Distribution Model (Additional Insight)

    12.1    Overview 
    12.2    Potential Distributors 
    12.3    Key Parameters for Distribution Partner Assessment 
13    Payment Methods (Additional Insight)
    13.1    Government Funded
    13.2    Private Insurance
    13.3    Out-of-Pocket

Key Questions Answered in the Report

The prevalence of iron deficiency anaemia is likely to grow at a CAGR of 4% during the forecast period of 2022-2030, which will boost the growth of the treatment market.

The high prevalence of chronic kidney disease, increasing number of patients and presence of major players focused on development, and marketing of technologically advanced products will drive the growth during the forecast period.

North America is the dominating region in the global market owing to the rising demand for the treatment in the region.

Amgen Inc., Hoffmann-La Roche Ltd, Novartis AG, Pfizer Inc, Janssen Pharmaceuticals, Inc., AMAG Pharmaceuticals, and Teva Pharmaceutical Industries Ltd. are the leading companies in the market.

The high cost of treatment will hinder the market growth. Lack of awareness of the treatment will restrain the growth of market.

The loss of blood and decrease in red blood cell production can lead to anaemia due to an iron deficiency or an increase in red blood cell destruction by haemolysis. The main cause of anaemia is iron deficiency.

MegaPro Biomedical and Nemysis are the emerging drugs which would drive the market growth.

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