The United States pharmaceutical logistics services market was valued at USD 28.06 Billion in 2025 and is expected to grow at a CAGR of 6.70%, reaching USD 53.67 Billion by 2035. The market is driven by the rising demand for temperature-sensitive biologics and specialty drugs across the region.
Base Year
Historical Period
Forecast Period
Cold-chain infrastructure innovation and real-time monitoring are expected to drive higher reliability and compliance in pharmaceutical logistics.
Major market trends include strategic mergers like DHL-Cryopdp indicate continued consolidation, expanding specialized service capabilities across biologics and clinical trial logistics.
The market growth is driven by dedicated healthcare facility investments by major players, that are likely to streamline delivery of high-value, temperature-sensitive pharmaceuticals across the U.S.
Compound Annual Growth Rate
6.7%
Value in USD Billion
2026-2035
*this image is indicative*
The pharmaceutical logistics market in the United States involves the secure transportation, storage, and handling of medicines, biologics, and clinical trial materials in compliance with FDA and DSCSA regulations. As of early 2025, more than 23,000 drug establishments are registered with the FDA, including over 1,500 licensed third-party logistics providers (3PLs) facilitating cold and ambient shipments. This market is crucial for maintaining drug integrity, managing supply chain traceability, and supporting patient access to medications and therapies nationwide. The market is anticipated to grow at a CAGR of 6.70% during the forecast period of 2026-2035.
Advanced Cold Chain Facility Upgrades Driving Market Growth
Rising biologics volume and cold-chain regulatory demands are key growth drivers. For instance, in April 2025, Porter Logistics partnered with Invensify to enhance its 145,000 sq ft facility in Chicago with cloud-enabled quantum shippers, enabling real-time temperature monitoring during storage and transport. This upgrade ensures compliance with FDA and ISP cold-chain guidelines, minimizes spoilage risk, and enhances distribution integrity. By adopting cutting-edge technology, the company meets the growing need for biologic delivery, reinforcing its competitive edge and fueling long-term market growth.
The market is witnessing several trends such as rising strategic acquisitions between key players, and efforts to expand infrastructure among others.
Strategic Acquisitions to Expand Cold-Chain Capabilities and Boost Market Value
Mergers and acquisitions are strengthening service capacity and geographic reach in pharmaceutical logistics. For instance, in March 2025, DHL acquired Cryopdp, a U.S.-based specialist in temperature-sensitive pharma logistics, for a substantial nine-figure investment. This acquisition reinforces DHL’s global footprint and expands its capabilities in clinical trial and biologics delivery. The move reflects a growing industry emphasis on consolidated, end-to-end service platforms tailored for the pharmaceutical sector. As demand for cold-chain services grows, strategic merger and acquisition activity are enhancing reliability, compliance, and innovation across supply chains.
Healthcare Facility Expansions are Expected to Boost United States Pharmaceutical Logistics Services Market Demand
Facility expansion dedicated to healthcare is driving innovation and reliability in pharmaceutical logistics. For instance, in May 2023, UPS Healthcare announced plans for seven new healthcare-dedicated facilities across the U.S., expanding its temperature-controlled capacity and automation capabilities. With ambitions to exceed USD 10 billion in healthcare logistics revenue, UPS is investing in advanced tracking systems, secure storage, and regulatory-ready distribution networks. These facilities aim to meet the rising logistical needs of complex pharmaceuticals, including biologics and specialty drugs, reinforcing the company's position as a leader in temperature-sensitive healthcare delivery.
Warehousing and Storage to Lead the Market Segmentation by Service Type
Warehousing and storage is expected to command the largest share of the market by service type. The increasing volume of biologics, vaccines, and temperature-sensitive therapies has led to greater demand for secure, compliant storage infrastructure. This segment benefits from stringent regulations and growing investment in cold chain capacity, positioning it as the core service ensuring product integrity and continuity across pharmaceutical supply chains. Its scalability and compliance advantages give it a competitive edge over other service categories.
The Far West region is expected to lead the market due to its advanced cold-chain infrastructure, biotech hubs in California, and major international ports. It supports high-volume biologics and vaccine distribution with regulatory readiness and multimodal access. The Great Lakes region follows, driven by strong pharmaceutical manufacturing in Illinois and Michigan and proximity to clinical trial centers. However, it lags in innovation density and specialized cold-chain infrastructure compared to the Far West’s more diversified logistics ecosystem.
The key features of the market report comprise strategic initiatives by the leading players. The major companies in the market are as follows:
Headquartered in Memphis, Tennessee, and founded in 1971, FedEx Corporation is a global logistics leader offering specialized pharmaceutical transportation solutions, including temperature-controlled shipping and real-time tracking. Through FedEx HealthCare Priority and FedEx SenseAware, the company ensures compliance with strict regulatory requirements for pharmaceutical products. FedEx also supports supply chain efficiency via its extensive U.S. distribution network, positioning itself as a key player in cold chain logistics for biologics and time-sensitive medications.
Established in 1907 and headquartered in Atlanta, Georgia, UPS plays a vital role in pharmaceutical logistics with its UPS Healthcare division. It offers secure cold chain transport, warehousing, and packaging for temperature-sensitive pharmaceuticals. With over 1 million square feet of healthcare-compliant space in the U.S. alone, UPS ensures end-to-end visibility and regulatory compliance. Its investment in facilities like the Louisville healthcare campus reinforces its role in addressing evolving biopharma logistics needs across the United States.
Deutsche Post AG, operating under the DHL brand, is a German logistics giant founded in 1995 and a significant contributor to U.S. pharmaceutical logistics through DHL Supply Chain and DHL Global Forwarding. The company provides Good Distribution Practice (GDP)-certified transport, temperature-controlled warehousing, and last-mile delivery solutions. Its U.S. pharmaceutical logistics hubs, equipped with validated cold chain systems and digital tracking, help ensure safe and compliant handling of vaccines, biologics, and controlled substances across the country.
DB Schenker, a division of Deutsche Bahn AG and headquartered in Essen, Germany, delivers integrated logistics and supply chain solutions for pharmaceutical companies in the U.S. market. With a presence in over 40 U.S. locations, it offers GDP-compliant warehousing, air and ocean freight, and specialized healthcare transport solutions. DB Schenker has invested in temperature-controlled infrastructure and digital monitoring to support pharmaceutical compliance standards, helping clients manage global-to-local logistics efficiently within strict regulatory frameworks.
*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*
Other players in the market include C.H. Robinson Worldwide, Inc., Kuehne + Nagel International AG, Thermo Fisher Scientific Inc. (Patheon Pharma Services), and Noatum Logistics.
"United States Pharmaceutical Logistic Services Market Report and Forecast 2026-2035” offers a detailed analysis of the market based on the following segments:
Market Breakup by Service Type
Market Breakup by Chain Type
Market Breakup by Mode of Transportation
Market Breakup by Application
Market Breakup by Region
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*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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| REPORT FEATURES | DETAILS |
| Base Year | 2025 |
| Historical Period | 2019-2025 |
| Forecast Period | 2026-2035 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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| Breakup by Service Type |
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| Breakup by Chain Type |
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| Breakup by Mode of Transportation |
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| Breakup by Application |
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| Breakup by Region |
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| Market Dynamics |
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| Supplier Landscape |
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| Companies Covered |
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