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Report Overview

Atherosclerotic cardiovascular disease (ASCVD) remains a major contributor to global morbidity and mortality. As per Muhammad Talha Maniya et al., 2025, prevalence is projected to increase from 11.3% in 2020 to 15.0% by 2050, rising from 28 million to 45 million affected individuals. According to the atherosclerotic cardiovascular disease epidemiology forecast by Expert Market Research, the rising burden highlights the growing need for preventive and therapeutic interventions.

2025

Base Year

2019-2025

Historical Period

2026-2035

Forecast Period

Atherosclerotic Cardiovascular Disease – Number of Cases by Year

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Atherosclerotic Cardiovascular Disease Epidemiology Forecast Report Coverage

Expert Market Research's “Atherosclerotic Cardiovascular Disease Epidemiology Forecast Report 2026-2035” offers comprehensive information on the prevalence and demographics of atherosclerotic cardiovascular disease. It projects the future incidence and prevalence rates of atherosclerotic cardiovascular disease cases across various populations. The study covers age, gender, and type as major determinants of the atherosclerotic cardiovascular disease population. The report highlights patterns in the prevalence of atherosclerotic cardiovascular disease over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of atherosclerotic cardiovascular disease in the 8 major markets.

Regions Covered

  • The United States
  • Germany
  • France
  • Italy
  • Spain
  • The United Kingdom
  • Japan
  • India

Atherosclerotic Cardiovascular Disease Understanding: Disease Overview

Atherosclerotic cardiovascular disease (ASCVD) is a chronic condition characterized by the accumulation of lipid-rich plaques within the walls of arteries, leading to narrowing and reduced blood flow. It develops through a complex process involving endothelial dysfunction, inflammation, and cholesterol deposition, particularly low-density lipoprotein cholesterol. Over time, plaque buildup may rupture and trigger blood clot formation, causing acute cardiovascular events. ASCVD primarily affects major arterial systems and includes conditions such as coronary artery disease, cerebrovascular disease, and peripheral artery disease. Major risk factors include hypertension, diabetes mellitus, smoking, obesity, and dyslipidemia.

Atherosclerotic Cardiovascular Disease Epidemiology Perspective

The atherosclerotic cardiovascular disease epidemiology division offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for the atherosclerotic cardiovascular disease epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for atherosclerotic cardiovascular disease and their trends. The data is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.

  • According to Muhammad Talha Maniya et al., 2025, atherosclerotic cardiovascular disease (ASCVD) contributes significantly to global cardiovascular mortality. In the United States, cardiovascular diseases caused 10.95 million deaths between 2010 and 2022, highlighting the major health burden associated with atherosclerosis-related conditions.
  • As per Muhammad Talha Maniya et al., 2025, age plays a critical role in ASCVD epidemiology. The incidence of cardiovascular diseases linked to atherosclerosis reaches 75–78% among individuals aged 60–80 years and rises to more than 85% in those older than 80 years.
  • According to Satyam Suman et al., 2023, gender differences are evident in atherosclerotic cardiovascular disease patterns. Men are three to four times more likely than women to develop ST-elevation or non-ST-elevation myocardial infarction, while ischemic heart disease typically appears 7–10 years later in women.
  • As per the American Heart Association study published in February 2026, the burden of atherosclerotic cardiovascular disease among women is projected to rise substantially, with six in ten women in the United States expected to develop a form of cardiovascular disease by 2050.
  • According to Muhammad Talha Maniya et al., 2025, the growing elderly population will further increase ASCVD prevalence. The United States population aged 65 years and older is projected to exceed 73.1 million by 2030, intensifying the burden of atherosclerosis-related cardiovascular conditions.

Atherosclerotic Cardiovascular Disease – Number of Cases by Country

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Country-wise Atherosclerotic Cardiovascular Disease Epidemiology

The atherosclerotic cardiovascular disease epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

The epidemiology of atherosclerotic cardiovascular disease (ASCVD) demonstrates substantial regional variation across major healthcare markets. According to Muhammad Talha Maniya et al., 2025, cardiovascular disease accounted for approximately 10.95 million deaths in the United States between 2010 and 2022, reflecting a significant ASCVD burden. In Spain, ASCVD affects nearly 10% of the population and contributes to about 28% of total mortality, as per Giancarlo Pesce et al., 2025. In India, the prevalence of peripheral arterial disease, an important ASCVD manifestation, ranges from 7.6% to 26.7% according to Khanna et al., 2023, highlighting a considerable disease burden in emerging economies. Similar epidemiological pressures are reported across United Kingdom, Germany, France, Italy, and Japan, reflecting the widespread global impact of ASCVD across developed and developing healthcare systems.

Atherosclerotic Cardiovascular Disease: Treatment Overview

Treatment of atherosclerotic cardiovascular disease focuses on reducing cardiovascular risk, slowing plaque progression, and preventing complications. Management typically includes lifestyle modifications such as smoking cessation, a heart-healthy diet, weight management, and regular physical activity. Pharmacological therapies play a key role and may include statins to lower low-density lipoprotein cholesterol, antiplatelet agents to prevent clot formation, antihypertensive medications, and glucose-lowering drugs for patients with diabetes. In advanced cases, interventional procedures such as percutaneous coronary intervention or coronary artery bypass grafting may be performed to restore adequate blood flow and reduce cardiovascular risk.

Key Questions Answered

  • What are the key findings of atherosclerotic cardiovascular disease epidemiology in the 8 major markets?
  • What will be the total number of patients with atherosclerotic cardiovascular disease across the 8 major markets during the forecast period?
  • What was the country-wise atherosclerotic cardiovascular disease epidemiology scenario in the 8 major markets in the historical period?
  • Which country will have the highest number of atherosclerotic cardiovascular disease patients during the forecast period of 2026-2035?
  • Which key factors would influence the shift in the patient population of atherosclerotic cardiovascular disease during the forecast period of 2026-2035?
  • What are the currently available treatments for atherosclerotic cardiovascular disease?
  • What are the disease risks, signs, symptoms, and unmet needs of atherosclerotic cardiovascular disease?

Scope of the Atherosclerotic Cardiovascular Disease Epidemiology Report

  • The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of atherosclerotic cardiovascular disease based on several factors.
  • Atherosclerotic Cardiovascular Disease Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
  • The atherosclerotic cardiovascular disease report helps to identify the patient population, and the unmet needs are highlighted along with an assessment of the disease's risk and burden.

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*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

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Details

Base Year

2025

Historical Period

2019-2025

Forecast Period

2026-2035

Epidemiology Statistics Provided

  • Diagnosed Prevalent Cases
  • Type-Specific Cases
  • Gender-Specific Cases
  • Age-Specific Cases

Segmentation Provided

  • Epidemiology by Age Group
  • Epidemiology by Gender
  • Epidemiology by Type of Disease
  • Epidemiology by Region

Geographies Covered

  • United States
  • Germany
  • Italy
  • France
  • Spain
  • United Kingdom
  • Japan
  • India

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