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Globally, castrate-resistant prostate cancer affects men with advanced prostate cancer, with non-metastatic CRPC representing about 8% of patients on androgen deprivation therapy and progression to metastasis occurring in roughly 20 months, highlighting the need for early detection and intervention. According to castrate resistant prostate cancer (CRPC) epidemiology forecast by Expert Market Research, biological factors such as higher Gleason grade, high PSA nadir after ADT, and short time to PSA nadir are associated with faster progression from hormone-sensitive prostate cancer to CRPC.
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Expert Market Research's “Castrate Resistant Prostate Cancer (CRPC) Epidemiology Forecast Report 2026-2035” offers comprehensive information on the prevalence and demographics of castrate resistant prostate cancer. It projects the future incidence and prevalence rates of castrate resistant prostate cancer cases across various populations. The study covers age, gender, and type as major determinants of the castrate resistant prostate cancer (CRPC) population. The report highlights patterns in the prevalence of castrate resistant prostate Cancer (CRPC) over time and projects future trends based on multiple variables.
The report provides a comprehensive overview of the disease, as well as historical and projected data on castrate resistant prostate cancer (CRPC) epidemiology in the 8 major markets.
Regions Covered
CRPC is a stage of prostate cancer where disease progresses despite androgen deprivation therapy, including surgical or chemical castration. Patients may present with rising prostate-specific antigen (PSA) levels, worsening symptoms, or new metastases. It can be classified as metastatic or non-metastatic, and symptomatic burden varies. CRPC predominantly affects older men, often leading to bone, lymph node, or visceral metastases, significantly impacting quality of life. Early identification and monitoring are crucial for timely intervention and improved survival outcomes.
The castrate resistant prostate cancer (CRPC) epidemiology division offers information on the patient pool from history to the present, as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for the castrate resistant prostate cancer (CRPC) epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for castrate resistant prostate Cancer (CRPC) and their trends. The castrate resistant prostate cancer (CRPC) detailed epidemiology segmentation is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.

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The castrate resistant prostate cancer (CRPC) epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.
In the United States, castrate-resistant prostate cancer (CRPC) represents a critical stage of prostate malignancy, with about 1.1% of prostate cancer patients identified as metastatic CRPC in a managed-care population. Prevalence has increased over time, reflecting longer survival with modern therapies. Median survival for metastatic CRPC patients is approximately 3 years, while the overall five-year survival rate for metastatic prostate cancer is around 38%, encompassing both hormone-sensitive and resistant cases. These data underscore the ongoing clinical burden of advanced prostate cancer and the importance of effective management strategies.
Management of CRPC involves a combination of hormonal therapies, chemotherapy, immunotherapy, and radiopharmaceuticals. Androgen receptor inhibitors like enzalutamide or apalutamide are used for non-metastatic disease, while docetaxel or cabazitaxel chemotherapy is indicated for advanced or metastatic cases. Bone-targeted therapies, such as radium-223, reduce skeletal complications. Treatment choice depends on metastatic status, patient comorbidities, prior therapy, and symptom burden, with multidisciplinary care improving survival and quality of life. Clinical trials explore novel combination therapies to delay progression further.
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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Base Year |
2025 |
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Historical Period |
2019-2025 |
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Forecast Period |
2026-2035 |
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