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Report Overview

Primary open-angle glaucoma (POAG) is the most prevalent form of glaucoma and a major cause of irreversible vision loss worldwide. Glaucoma affected nearly 76 million people globally in 2020, projected to reach 111.8 million by 2040. Primary open-angle glaucoma (POAG), the most common subtype, accounts for approximately 3.1% prevalence among adults aged 40 years and older. The growing burden is linked to aging populations and improved detection rates. According to primary open angle glaucoma epidemiology forecast by Expert Market Research, increasing intraocular pressure remains a key clinical indicator driving diagnosis, monitoring, and long-term disease management strategies worldwide.

2025

Base Year

2019-2025

Historical Period

2026-2035

Forecast Period

Primary Open Angle Glaucoma – Number of Cases by Year

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Primary Open Angle Glaucoma Epidemiology Forecast Report Coverage

Expert Market Research's “Primary Open Angle Glaucoma Epidemiology Forecast Report 2026-2035” offers comprehensive information on the prevalence and demographics of primary open angle glaucoma. It projects the future incidence and prevalence rates of primary open angle glaucoma cases across various populations. The study covers age, gender, and type as major determinants of the primary open angle glaucoma population. The report highlights patterns in the prevalence of primary open angle glaucoma over time and projects future trends based on multiple variables.

Primary Open Angle Glaucoma Understanding: Disease Overview

POAG is a chronic, progressive optic neuropathy characterized by gradual vision loss due to optic nerve damage. It is the most common form of glaucoma worldwide and often remains asymptomatic in early stages, leading to delayed diagnosis. Elevated intraocular pressure is a major risk factor, though normal-tension cases also occur. The disease is associated with impaired aqueous humor drainage through the trabecular meshwork. Risk increases with age, family history, diabetes, and myopia. Without timely management, irreversible visual field loss and blindness may develop gradually over time in untreated cases globally.

Primary Open Angle Glaucoma Epidemiology Perspective

The primary open angle glaucoma epidemiology division offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for the primary open angle glaucoma epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for primary open angle glaucoma and their trends. The data is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.

  • According to Sujan Banik et al., 2025, the pooled prevalence of primary open angle glaucoma (POAG) in South Asia was 1.6% (95% confidence interval 1.2–2.1), within an overall glaucoma prevalence of 2.1%, confirming POAG as the most dominant subtype regionally.
  • According to Kelsey V. Stuart et al., 2025, age-wise prevalence increased sharply from 0.22% in individuals aged 40–44 years to 10.74% in those aged 85 years and above, demonstrating a strong correlation between advancing age and higher POAG burden, reflecting progressive optic nerve damage over time.
  • According to Sujan Banik et al., 2025, gender differences showed POAG prevalence was higher in males (2.26%) than females (1.61%), with overall open-angle glaucoma prevalence also slightly higher in men (2.2%) compared to women (2.0%), indicating consistent male predominance.
  • According to Joshua R. Ehrlich et al., 2024, glaucoma affected approximately 4.22 million individuals in the United States in 2022, with prevalence of 1.62% among adults aged 18 years or older and 2.56% among those aged 40 years or older.
  • According to Joshua R. Ehrlich et al., 2024, around 1.49 million individuals had vision-affecting glaucoma, with prevalence of 0.57% in adults aged 18 years or older and 0.91% in those aged 40 years or older, highlighting significant burden of visual field loss and long-term disability.

Primary Open Angle Glaucoma – Number of Cases by Country

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Country-wise Primary Open Angle Glaucoma Epidemiology

The primary open angle glaucoma epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

Across the regions, the epidemiology reflects a substantial and growing public health burden. According to Jonathan S. Myers et al., 2025, glaucoma accounts for 9-12% of blindness in the United States, with prevalence among Medicare Fee-for-Service enrollees increasing from 12.7% in 2014 to 13.6% in 2019, and nearly 80% of cases being open-angle glaucoma. As per Sujan Banik et al., 2025, the global prevalence of POAG is approximately 3.1% among individuals aged 40 years and older, including populations across the United Kingdom, Germany, France, Spain, Italy, Japan, and India, consistent regional disease burden driven by rising intraocular pressure and aging populations.

Primary Open Angle Glaucoma: Treatment Overview

Treatment of POAG focuses on lowering intraocular pressure to slow disease progression and preserve vision. First-line glaucoma treatment includes pharmacologic therapy, primarily eye drops such as prostaglandin analogs, beta blockers, alpha agonists, and carbonic anhydrase inhibitors. These agents improve aqueous outflow or reduce production. Laser trabeculoplasty may be used when medications are insufficient. In advanced cases, surgical interventions like trabeculectomy or minimally invasive glaucoma surgery are recommended. Lifelong monitoring is essential to adjust therapy and prevent optic nerve deterioration and visual field loss, and maintain long term visual function outcomes effectively managed.

Key Questions Answered

  • What are the key findings of primary open angle glaucoma epidemiology in the 8 major markets?
  • What will be the total number of patients with primary open angle glaucoma across the 8 major markets during the forecast period?
  • What was the country-wise primary open angle glaucoma epidemiology scenario in the 8 major markets in the historical period?
  • Which country will have the highest number of primary open angle glaucoma patients during the forecast period of 2026-2035?
  • Which key factors would influence the shift in the patient population of primary open angle glaucoma during the forecast period of 2026-2035?
  • What are the currently available treatments for primary open angle glaucoma?
  • What are the disease risks, signs, symptoms, and unmet needs of primary open angle glaucoma?

Scope of the Primary Open Angle Glaucoma Epidemiology Report

  • The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of primary open angle glaucoma based on several factors.
  • Primary Open Angle Glaucoma Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
  • The primary open angle glaucoma report helps to identify the patient population, and the unmet needs are highlighted along with an assessment of the disease's risk and burden.

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Glaucoma Epidemiology Forecast

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*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

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Base Year

2025

Historical Period

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Forecast Period

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Epidemiology Statistics Provided

  • Diagnosed Prevalent Cases
  • Type-Specific Cases
  • Gender-Specific Cases
  • Age-Specific Cases

Segmentation Provided

  • Epidemiology by Age Group
  • Epidemiology by Gender
  • Epidemiology by Type of Disease
  • Epidemiology by Region

Geographies Covered

  • United States
  • Germany
  • Italy
  • France
  • Spain
  • United Kingdom
  • Japan
  • India

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