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Report Overview

Open-angle glaucoma is a progressive eye disease that damages the optic nerve, often associated with elevated intraocular pressure. As per the Glaucoma Research Foundation, approximately 80 million people worldwide had glaucoma in 2020, including about 60 million with open-angle glaucoma. According to the open-angle glaucoma epidemiology forecast by Expert Market Research, the optic nerve remains central to disease assessment and progression.

2025

Base Year

2019-2025

Historical Period

2026-2035

Forecast Period

Open-Angle Glaucoma – Number of Cases by Year

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Open-Angle Glaucoma Epidemiology Forecast Report Coverage

Expert Market Research's “Open-Angle Glaucoma Epidemiology Forecast Report 2026-2035” offers comprehensive information on the prevalence and demographics of open-angle glaucoma. It projects the future incidence and prevalence rates of open-angle glaucoma cases across various populations. The study covers age, gender, and type as major determinants of the open-angle glaucoma population. The report highlights patterns in the prevalence of open-angle glaucoma over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of open-angle glaucoma in the 8 major markets.

Regions Covered

  • United States
  • Germany
  • France
  • Italy
  • Spain
  • United Kingdom
  • Japan
  • India

Open-Angle Glaucoma Understanding: Disease Overview

Open-angle glaucoma is a chronic, progressive optic neuropathy characterized by damage to the optic nerve and corresponding visual field loss, typically with an anatomically open anterior chamber angle. The disease commonly develops when aqueous humor drainage through the trabecular meshwork becomes impaired, resulting in elevated or dysregulated intraocular pressure and progressive retinal ganglion cell loss. The principal types include primary open-angle glaucoma (POAG), the most common form, and secondary open-angle glaucoma, which may result from conditions such as pseudoexfoliation, pigment dispersion, trauma, inflammation, or corticosteroid exposure.

Key Report Insights

Parameter

Insight

Largest Patient Pool

United States

Fastest Growing Country

India

High-Risk Population

Older adults, particularly those aged 60 years and older

Key Diagnostic Method

Comprehensive ophthalmic examination

Major Risk Factor

Older age

Major gap in the market

Underdiagnosis and delayed detection

Open-Angle Glaucoma Epidemiology Perspective

The open-angle glaucoma epidemiology division offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for the open-angle glaucoma epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for open-angle glaucoma and their trends. The data is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.

Epidemiology Segment

Key Insights

Diagnosed Prevalent Cases of the Disease

As per Glaucoma Research Foundation (2020), approximately 80 million people worldwide had glaucoma, including around 60 million with open-angle glaucoma, indicating a substantial global disease burden.

Gender-Specific Cases of the Disease

According to European Glaucoma Society (2025), male sex was associated with higher glaucoma prevalence in European population-based studies. The analysis included 55,415 adults aged 40 years and older.

Age-Specific Cases of the Disease

According to European Glaucoma Society (2025), glaucoma prevalence increases with age. In Europe, older age was significantly associated with higher prevalence, while younger individuals had a greater proportion of undiagnosed disease.

Ethnicity-Wise Cases of the Disease

According to BrightFocus Foundation, primary open-angle glaucoma affects African Americans at younger ages and is approximately three to four times more common than among people of European ancestry. Hispanic prevalence was intermediate.

Mortality and Survival Analysis of the Disease

Long-term outcomes are primarily associated with the progression of vision loss and the extent of optic nerve damage, with disease progression potentially affecting visual function and quality of life.

Type-Specific Disease Burden and Epidemiology Analysis

Disease Type

Prevalence

Primary Open-Angle Glaucoma (POAG)

According to Selvaraj Jerrome et al. (2026), the pooled prevalence of primary open-angle glaucoma in India was 2.07%. Prevalence varied according to age, gender, geographic zone, habitation, and diagnostic criteria.

Normal-Tension Glaucoma (NTG)

Normal-tension glaucoma is identified as a subtype of open-angle glaucoma in the provided information. The supplied epidemiological data do not provide a prevalence value for this subtype.

Pigmentary Glaucoma

Pigmentary glaucoma is identified as a secondary open-angle subtype in the provided information. The supplied epidemiological data do not provide a prevalence value for this subtype.

Pseudoexfoliation Glaucoma

According to Selvaraj Jerrome et al. (2026), pseudoexfoliation glaucoma was included with secondary glaucoma, with a combined pooled prevalence of 0.29% in India.

Open-Angle Glaucoma – Number of Cases by Country

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Country-wise Open-Angle Glaucoma Epidemiology

The open-angle glaucoma epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

Country

Key Insights

United States

According to Glaucoma Research Foundation (2020), approximately 60 million of the estimated 80 million people worldwide with glaucoma were affected by open-angle glaucoma. The provided information also indicates younger onset among African Americans.

Germany

According to Tienan Qi et al. (2025), open-angle glaucoma prevalence increased with age in Germany, from approximately 0.4% among people aged 40–44 years to 10% among those older than 90 years.

France

According to European Glaucoma Society, the European glaucoma burden is associated with increasing age, and primary open-angle glaucoma represents a substantial component of the overall disease burden.

Italy

As per European Glaucoma Society, glaucoma prevalence in European populations increases with age. The European analysis also identified a substantial proportion of previously undiagnosed cases, particularly among younger participants.

Spain

According to European Glaucoma Society, glaucoma prevalence varies across European populations and increases with age. The analysis also identified a substantial burden of previously undiagnosed glaucoma.

United Kingdom

As per European Glaucoma Society, glaucoma prevalence increases with age among European adults aged 40 years and older. More than half of identified cases in the European analysis had been previously undiagnosed.

Japan

In Japan, age is an important epidemiological factor for glaucoma, with prevalence increasing with advancing age in the reported populations.

India

According to Selvaraj Jerrome et al. (2026), pooled glaucoma prevalence in India was 3.23%, including 2.07% for primary open-angle glaucoma. Prevalence varied by age, gender, geographic zone, habitation, and diagnostic criteria.

Key Market Gaps, Untapped Opportunities, and Emerging Growth Areas in the Regional Disease Epidemiology Landscape

The regional open-angle glaucoma landscape continues to face a substantial early-detection gap, particularly because glaucoma can progress with limited symptoms before irreversible visual impairment becomes apparent. Recent European evidence indicates that more than half of glaucoma cases may remain undiagnosed, underscoring the need for broader population risk assessment and timely ophthalmic evaluation. Aging populations across the United States, Europe, Japan, and India are expected to increase the underlying disease burden. Opportunities include expanded screening of high-risk populations, improved access to comprehensive eye examinations, earlier diagnosis, and greater use of technologies that support optic nerve and visual field assessment.

Open-Angle Glaucoma: Treatment Overview

Open-angle glaucoma treatment aims to slow or prevent further optic nerve damage and preserve visual function, primarily by lowering intraocular pressure. First-line management commonly involves topical medications, including prostaglandin analogs, beta-blockers, alpha-adrenergic agonists, and carbonic anhydrase inhibitors. Selective laser trabeculoplasty may be used as an initial or adjunctive treatment. For patients with inadequate control or progressive disease, surgical device approaches such as minimally invasive glaucoma surgery, trabeculectomy, or glaucoma drainage devices may be considered. Intraocular pressure reduction remains the central therapeutic objective throughout disease management.

Key Questions Answered

  • What is the current and projected burden of open-angle glaucoma across the 8 major markets?
  • Which countries across the 8 major markets account for the highest open-angle glaucoma patient populations and fastest growth rates?
  • What is the diagnosed versus undiagnosed patient population of open-angle glaucoma across key countries in the 8 major markets?
  • Which countries demonstrate the largest gaps in screening, early diagnosis, and disease awareness of open-angle glaucoma across the 8 major markets?
  • What are the major drivers contributing to the increasing burden of open-angle glaucoma across the 8 major markets?
  • How do major comorbidities and risk factors influence open-angle glaucoma trends across the 8 major markets?
  • What are the regional trends in advanced disease progression, treatment uptake, and patient management of open-angle glaucoma across the 8 major markets?
  • Which patient segments represent the highest unmet clinical need in the open-angle glaucoma landscape across the 8 major markets?
  • Which therapeutic areas linked to open-angle glaucoma are expected to witness the strongest growth opportunities across the 8 major markets?
  • How is the open-angle glaucoma epidemiology landscape expected to evolve over the next 5 to 10 years across the 8 major markets?
  • Which countries across the 8 major markets offer the most attractive market opportunities based on open-angle glaucoma epidemiology and healthcare infrastructure?
  • Which epidemiological trends are expected to influence future drug development and market access strategies for open-angle glaucoma across the 8 major markets?

Scope of the Open-Angle Glaucoma Epidemiology Report

  • The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of open-angle glaucoma based on several factors.
  • Open-Angle Glaucoma Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
  • The open-angle glaucoma report helps to identify the patient population, and the unmet needs are highlighted along with an assessment of the disease's risk and burden.

Related Reports

Glaucoma Therapeutics Market

Glaucoma Pipeline Analysis

Primary Open Angle Glaucoma Epidemiology Forecast

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

Report Features

Details

Base Year

2025

Historical Period

2019-2025

Forecast Period

2026-2035

Epidemiology Statistics Provided

  • Diagnosed Prevalent Cases
  • Type-Specific Cases
  • Gender-Specific Cases
  • Age-Specific Cases

Segmentation Provided

  • Epidemiology by Age Group
  • Epidemiology by Gender
  • Epidemiology by Type of Disease
  • Epidemiology by Region

Geographies Covered

  • United States
  • Germany
  • Italy
  • France
  • Spain
  • United Kingdom
  • Japan
  • India

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