Clofazimine Price Trend and Forecast 2026-2027

Clofazimine prices in Germany, the highest-cost reporting region, rose 7.0% in H1 2026, climbing from USD 110.4/KG in Q1 to USD 118.1/KG by Q2 as recovering leprosy multidrug therapy, MDR-TB treatment regimen, and atypical mycobacterial infection procurement and firmer riminophenazine synthesis intermediate costs reversed the H2 2025 API market softening. Globally, the average rose from USD 77.91/KG in Q1 to USD 83.36/KG in Q2, a 7.0% gain. For H2 2026, a global average of USD 84.20-92.80/KG is expected, with continued firming on Middle East supply disruptions and growing WHO leprosy MDT and MDR-TB treatment sector demand globally.

Clofazimine is a riminophenazine antiinfective produced by condensation synthesis of 2-hydroxy-3-phenazinecarbonitrile with 4-chloroaniline and isopropylamine under controlled conditions to yield the 3-(p-chloroanilino)-10-(isopropyl)-2,10-dihydro-3H-phenothiazin-2-ylideneamine active structure, a substituted iminophenazine dye derivative with deep red-brown colour and lipophilic properties. The compound exerts its antimycobacterial activity through multiple mechanisms including binding to guanine bases in mycobacterial DNA, generation of reactive oxygen species through electron transport chain disruption, and inhibition of potassium ion transport, producing bactericidal and bacteriostatic effects against slowly replicating mycobacteria including Mycobacterium leprae, Mycobacterium tuberculosis complex, and non-tuberculous mycobacterial species. The largest pull comes from WHO multidrug therapy programmes for leprosy elimination, where clofazimine is a mandatory component of the standard multibacillary and paucibacillary treatment regimens procured through the WHO drug donation programme and national leprosy elimination programmes. MDR-TB and extensively drug-resistant TB treatment regimens endorsed by WHO guidance add a significant and rapidly growing demand segment. Non-tuberculous mycobacterial infection treatment in immunocompromised patients adds further volume. Synthesis intermediate costs, WHO leprosy and MDR-TB programme procurement, and regional API capacity all feed into the price.

Clofazimine Price Forecast for 2026

The balance of supply and demand for clofazimine through H2 2026 leans moderately firm. Riminophenazine synthesis intermediate costs firmed from Middle East supply disruptions. WHO MDR-TB treatment guideline adoption, global leprosy elimination programme procurement, and growing NTM infection management are expanding the demand base significantly.

The main upside risk is synthesis intermediate cost increases alongside accelerating MDR-TB programme scale-up procurement. The main downside risk is continued Chinese and Indian API surplus and competitive pricing maintaining pressure below forecast.

For the Quarter Ending June 2026

Clofazimine Prices Q2 2026:

• United States: USD 95.9/KG
• China: USD 66.6/KG
• Germany: USD 118.1/KG
• India: USD 90.2/KG

Clofazimine Prices in the United States

US Clofazimine prices averaged USD 95.9/KG in Q2 2026, up 7.0% from USD 89.6/KG in Q1 2026. Firmer synthesis intermediate costs and recovering MDR-TB treatment regimen and leprosy MDT procurement drove consistent buying through the quarter.

Why did the price of Clofazimine change in Q2 2026 in the United States?

Firmer riminophenazine synthesis intermediate costs raised the API production floor. MDR-TB treatment regimen, WHO leprosy MDT, and NTM infection procurement lifted buying. Immunocompromised patient atypical mycobacterial treatment demand provided additional support near USD 95.9/KG.

Clofazimine Prices in China

Chinese Clofazimine prices averaged USD 66.6/KG in Q2 2026, up 7.1% from USD 62.2/KG in Q1 2026, the lowest among the tracked markets. Spring MDR-TB and leprosy MDT export and domestic procurement lifted buying. Firmer domestic synthesis costs raised the floor despite domestic API capacity.

Why did the price of Clofazimine change in Q2 2026 in China?

Spring MDR-TB and leprosy MDT export and domestic procurement lifted buying. Firmer domestic riminophenazine synthesis intermediate costs raised the production floor. Domestic API capacity kept China the most affordable source.

Clofazimine Prices in Germany

German Clofazimine prices averaged USD 118.1/KG in Q2 2026, up 7.0% from USD 110.4/KG in Q1 2026, the highest among the tracked markets. Higher synthesis intermediate and energy costs elevated European API production economics. Recovering MDR-TB treatment, leprosy MDT, and NTM infection demand maintained consistent buying.

Why did the price of Clofazimine change in Q2 2026 in Germany?

Higher riminophenazine synthesis intermediate and energy costs elevated European API production economics. Middle East supply disruptions added cost premiums to phenazine synthesis substrate chains. Recovering MDR-TB, leprosy MDT, and NTM infection procurement maintained buying near USD 118.1/KG.

Clofazimine Prices in India

Indian Clofazimine prices averaged USD 90.2/KG in Q2 2026, up 7.0% from USD 84.3/KG in Q1 2026. Growing leprosy MDT, MDR-TB treatment, and export demand supported buying. Firmer synthesis import costs raised the production floor through the quarter.

Why did the price of Clofazimine change in Q2 2026 in India?

Growing WHO leprosy MDT and MDR-TB treatment export and domestic procurement lifted buying. Firmer riminophenazine synthesis import costs raised the production floor. NTM infection treatment export demand provided additional buying support near USD 90.2/KG.

For the Quarter Ending March 2026

Clofazimine Prices Q1 2026:

• United States: USD 89.6/KG
• China: USD 62.2/KG
• Germany: USD 110.4/KG
• India: USD 84.3/KG

Clofazimine Prices in the United States

US Clofazimine prices averaged USD 89.6/KG in Q1 2026, recovering about 4.0% from the Q4 2025 softening trough. Recovering MDR-TB and leprosy MDT demand and firming synthesis costs held the market near USD 89.6/KG.

Why did the price of Clofazimine change in Q1 2026 in the United States?

Recovering MDR-TB treatment regimen and leprosy MDT procurement maintained buying. Firming riminophenazine synthesis intermediate costs raised the production floor. The market recovered to USD 89.6/KG from the H2 2025 API softening trough.

Clofazimine Prices in China

Chinese prices averaged USD 62.2/KG in Q1 2026, recovering about 4.0% from Q4 2025. Post-Lunar New Year MDR-TB and leprosy MDT restocking and firming synthesis costs held the market near USD 62.2/KG.

Why did the price of Clofazimine change in Q1 2026 in China?

Post-Lunar New Year MDR-TB and leprosy MDT restocking lifted buying. Firming domestic synthesis intermediate costs raised the production floor. The market recovered to USD 62.2/KG from the H2 2025 trough.

Clofazimine Prices in Germany

German prices averaged USD 110.4/KG in Q1 2026, recovering about 4.0% from Q4 2025. Recovering MDR-TB and leprosy MDT demand and firming synthesis and energy costs held the market near USD 110.4/KG.

Why did the price of Clofazimine change in Q1 2026 in Germany?

Recovering MDR-TB and leprosy MDT procurement maintained buying. Firming synthesis intermediate and energy costs held the production floor. The market recovered to USD 110.4/KG from the H2 2025 trough.

Clofazimine Prices in India

Indian prices averaged USD 84.3/KG in Q1 2026, recovering about 4.0% from Q4 2025. Growing leprosy MDT and MDR-TB demand and firming synthesis import costs held the market near USD 84.3/KG.

Why did the price of Clofazimine change in Q1 2026 in India?

Growing WHO leprosy MDT and MDR-TB treatment export and domestic procurement maintained buying. Firming synthesis import costs raised the production floor. The market recovered to USD 84.3/KG from the H2 2025 API softening trough.

Quarterly Clofazimine Price Trends

Global Clofazimine prices declined through H2 2025 on API synthesis cost softening before recovering firmly through Q1 and Q2 2026. The average fell from USD 78.0/KG in Q2 2025 to USD 76.44/KG in Q3 and USD 74.91/KG in Q4, then recovered to USD 77.91/KG in Q1 2026 and USD 83.36/KG in Q2 2026, a net gain of about 6.9% over the window. Riminophenazine synthesis intermediate cost cycles and WHO leprosy MDT and MDR-TB programme procurement drove the H2 2025 softening and H1 2026 recovery.

What was Clofazimine Price in 2025?

Clofazimine prices declined through 2025 as API synthesis cost softening and moderated WHO programme procurement weighed on the market. The global average opened near USD 80.0/KG in Q1 2025 and closed at USD 74.91/KG in Q4, a full-year decline of about 6.4%. Synthesis intermediate cost softening and Chinese API supply adequacy maintained downward pressure before the H1 2026 recovery.

Clofazimine Prices in the United States in 2025

US prices fell from about USD 90.5/KG in Q1 2025 to USD 86.2/KG by Q4, a decline of 4.8%. Synthesis cost softening and adequate API supply maintained the downward trend.

Clofazimine Prices in China in 2025

Chinese prices fell from roughly USD 62.8/KG in Q1 2025 to USD 59.8/KG by Q4, a decline of 4.8%. Domestic API capacity and competitive pricing maintained the lowest level throughout.

Clofazimine Prices in Germany in 2025

German prices fell from about USD 111.5/KG in Q1 2025 to USD 106.2/KG by Q4, a decline of 4.8%. Synthesis intermediate cost softening and moderated European MDR-TB procurement maintained the decline through the year.

Clofazimine Prices in India in 2025

Indian prices fell from roughly USD 85.2/KG in Q1 2025 to USD 81.1/KG by Q4, a decline of 4.8%. Synthesis import cost softening and competitive export API pricing maintained downward pressure.

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Expert Market Research tracks Clofazimine prices continuously across every major producing and consuming region. The team traces causation through riminophenazine synthesis intermediate economics, WHO leprosy MDT and MDR-TB treatment procurement cycles, and regional API production capacity. Contact Expert Market Research today for Clofazimine pricing data, bespoke market analysis, and strategic procurement advisory.