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Sulfanilamide Prices, Demand and Supply Overview
Sulfanilamide prices in Germany, the highest-cost reporting region, rose 6.1% in H1 2026, climbing from USD 26.1/KG in Q1 to USD 27.7/KG by Q2 as firmer para-aminobenzenesulfonamide synthesis feedstock costs and recovering antibiotic formulation and sulfonamide synthesis intermediate procurement reversed the brief Q4 2025 market correction. Globally, the average rose from USD 18.54/KG in Q1 to USD 19.65/KG in Q2, a 6.0% gain. For H2 2026, a global average of USD 19.80-22.20/KG is expected, with continued firming on Middle East supply disruptions and growing topical antibiotic and sulfonamide synthesis intermediate sector demand globally.
Sulfanilamide, named 4-aminobenzenesulfonamide, is the simplest sulfonamide and parent structural compound of the broader sulfonamide antibiotic class, produced by the classical synthesis starting from aniline through acetylation to acetanilide, chlorosulfonation to form the 4-acetamidobenzenesulfonyl chloride intermediate, controlled aminolysis with ammonium carbonate or aqueous ammonia to the sulfonamide, and final acid hydrolysis to reveal the free 4-aminophenyl amine group. The compound exerts bacteriostatic activity through competitive inhibition of dihydropteroate synthase, blocking bacterial folate biosynthesis by displacing para-aminobenzoic acid from the enzyme active site and depriving susceptible organisms of tetrahydrofolate precursors essential for nucleic acid synthesis. The largest pull comes from direct topical antibiotic use in burn wound and skin infection management formulations, and from pharmaceutical synthesis intermediate applications as the parent compound for sulfamethoxazole, sulfadiazine, sulfacetamide, and other clinically used sulfonamide derivatives that collectively drive substantial industrial procurement. Synthetic dye and agrochemical intermediate applications add further consistent volume globally. Aniline and sulfonation synthesis feedstock costs, pharmaceutical intermediate procurement volumes, and regional production capacity all feed into the price.
Sulfanilamide Price Forecast for 2026
The balance of supply and demand for sulfanilamide through H2 2026 leans moderately firm. Aniline and sulfonation reagent synthesis feedstock costs firmed from Middle East aromatic chemical supply disruptions. Topical antibiotic formulation demand and pharmaceutical sulfonamide intermediate synthesis procurement are growing with expanding dermatology and antimicrobial access programme activity globally.
The main upside risk is aniline and aromatic synthesis feedstock cost increases alongside accelerating sulfonamide intermediate and topical antibiotic procurement. The main downside risk is continued Chinese production surplus maintaining competitive price pressure below forecast.
| Region | Price Forecast (USD/KG) | Key Driver |
| Global Average | 19.80 - 22.20 | Synthesis cost firming and sulfonamide/antibiotic demand support |
| United States | 21.20 - 23.60 | Steady topical and synthesis intermediate demand holds firm |
| China | 14.90 - 17.30 | Large production capacity keeps it the most affordable |
| Germany | 27.80 - 30.20 | High synthesis and energy costs keep it the most expensive |
| India | 20.30 - 22.70 | Growing intermediate and export demand holds a firm middle |
For the Quarter Ending June 2026
Sulfanilamide Prices Q2 2026:
- United States: USD 22.5/KG
- China: USD 15.7/KG
- Germany: USD 27.7/KG
- India: USD 21.4/KG
Sulfanilamide Prices in the United States
US Sulfanilamide prices averaged USD 22.5/KG in Q2 2026, up 6.1% from USD 21.2/KG in Q1 2026. Firmer synthesis feedstock costs and spring topical antibiotic and sulfonamide intermediate procurement drove consistent buying through the quarter.
Why did the price of Sulfanilamide change in Q2 2026 in the United States?
Firmer aniline and sulfonation synthesis feedstock costs raised the production floor. Topical burn wound antibiotic and pharmaceutical sulfonamide synthesis intermediate procurement lifted buying. Pharmaceutical dye and agrochemical intermediate demand provided additional support near USD 22.5/KG.
Sulfanilamide Prices in China
Chinese Sulfanilamide prices averaged USD 15.7/KG in Q2 2026, up 6.1% from USD 14.8/KG in Q1 2026, the lowest among the tracked markets. Spring pharmaceutical intermediate and topical antibiotic export procurement lifted buying. Firmer domestic synthesis costs raised the floor despite domestic production capacity.
Why did the price of Sulfanilamide change in Q2 2026 in China?
Spring pharmaceutical sulfonamide intermediate and topical antibiotic export and domestic procurement lifted buying. Firmer domestic aniline synthesis feedstock costs raised the production floor. Domestic production capacity kept China the most affordable source.
Sulfanilamide Prices in Germany
German Sulfanilamide prices averaged USD 27.7/KG in Q2 2026, up 6.1% from USD 26.1/KG in Q1 2026, the highest among the tracked markets. Higher aniline synthesis feedstock and energy costs elevated European production economics. Consistent topical antibiotic and sulfonamide synthesis intermediate procurement maintained buying.
Why did the price of Sulfanilamide change in Q2 2026 in Germany?
Higher aniline synthesis feedstock and energy costs elevated European production economics. Middle East supply disruptions added cost premiums to benzene-derived aromatic feedstock chains. Consistent topical antibiotic and pharmaceutical intermediate procurement maintained buying near USD 27.7/KG.
Sulfanilamide Prices in India
Indian Sulfanilamide prices averaged USD 21.4/KG in Q2 2026, up 5.9% from USD 20.2/KG in Q1 2026. Growing pharmaceutical sulfonamide intermediate and topical antibiotic export and domestic demand supported buying. Firmer synthesis import costs raised the production floor through the quarter.
Why did the price of Sulfanilamide change in Q2 2026 in India?
Growing pharmaceutical sulfonamide intermediate export and domestic procurement lifted buying. Firmer aniline synthesis import costs raised the production floor. Topical antibiotic export demand provided additional buying support near USD 21.4/KG.
For the Quarter Ending March 2026
Sulfanilamide Prices Q1 2026:
- United States: USD 21.2/KG
- China: USD 14.8/KG
- Germany: USD 26.1/KG
- India: USD 20.2/KG
Sulfanilamide Prices in the United States
US Sulfanilamide prices averaged USD 21.2/KG in Q1 2026, recovering about 1.9% from Q4 2025. Recovering topical antibiotic and sulfonamide intermediate demand and firming synthesis costs held the market near USD 21.2/KG.
Why did the price of Sulfanilamide change in Q1 2026 in the United States?
Recovering topical antibiotic and pharmaceutical sulfonamide intermediate procurement maintained buying. Firming aniline synthesis feedstock costs raised the production floor. The market recovered to USD 21.2/KG from the Q4 2025 correction.
Sulfanilamide Prices in China
Chinese prices averaged USD 14.8/KG in Q1 2026, recovering about 2.1% from Q4 2025. Post-Lunar New Year sulfonamide intermediate export restocking and firming costs held the market near USD 14.8/KG.
Why did the price of Sulfanilamide change in Q1 2026 in China?
Post-Lunar New Year pharmaceutical sulfonamide intermediate and topical antibiotic restocking lifted buying. Firming domestic synthesis costs raised the production floor. The market recovered to USD 14.8/KG from the Q4 2025 correction.
Sulfanilamide Prices in Germany
German prices averaged USD 26.1/KG in Q1 2026, recovering about 2.0% from Q4 2025. Recovering topical antibiotic and sulfonamide intermediate demand and firming synthesis and energy costs held the market near USD 26.1/KG.
Why did the price of Sulfanilamide change in Q1 2026 in Germany?
Recovering topical antibiotic and pharmaceutical sulfonamide intermediate procurement maintained buying. Firming synthesis feedstock and energy costs held the production floor. The market recovered to USD 26.1/KG from the Q4 2025 correction.
Sulfanilamide Prices in India
Indian prices averaged USD 20.2/KG in Q1 2026, recovering about 2.0% from Q4 2025. Growing pharmaceutical intermediate and topical antibiotic demand and firming import costs held the market near USD 20.2/KG.
Why did the price of Sulfanilamide change in Q1 2026 in India?
Growing pharmaceutical sulfonamide intermediate and topical antibiotic export and domestic procurement maintained buying. Firming synthesis import costs raised the production floor. The market recovered to USD 20.2/KG from the Q4 2025 correction.
Quarterly Sulfanilamide Price Trends
Global Sulfanilamide prices rose in Q3 2025 on the sulfonamide intermediate procurement season, dipped in Q4 2025 on synthesis feedstock moderation, then recovered through Q1 and Q2 2026. The average rose from USD 18.0/KG in Q2 2025 to USD 18.36/KG in Q3, eased to USD 18.18/KG in Q4, then firmed to USD 18.54/KG in Q1 2026 and USD 19.65/KG in Q2 2026, a net gain of about 9.2% over the window. Aniline synthesis feedstock cost cycles and sulfonamide intermediate and topical antibiotic procurement drove the overall pattern.
| Quarter | Price (USD/KG) | QoQ Change | Direction |
| Q2 2026 | 19.65 | +6.0% | ↑ Rising |
| Q1 2026 | 18.54 | +2.0% | ↑ Rising |
| Q4 2025 | 18.18 | -1.0% | ↓ Falling |
| Q3 2025 | 18.36 | +2.0% | ↑ Rising |
| Q2 2025 | 18.0 | - | - Stable |
| Q3 2026 | In Progress | - | - In Progress |
What was Sulfanilamide Price in 2025?
Sulfanilamide prices firmed modestly through 2025 on consistent pharmaceutical intermediate and topical antibiotic demand. The global average opened near USD 17.8/KG in Q1 2025 and closed at USD 18.18/KG in Q4, a full-year gain of about 2.1%. Aniline synthesis feedstock dynamics and sulfonamide intermediate procurement drove the quarterly pattern throughout the year.
Sulfanilamide Prices in the United States in 2025
US prices firmed from about USD 20.5/KG in Q1 2025 to USD 20.8/KG by Q4, a gain of 1.5%. Consistent topical antibiotic and pharmaceutical sulfonamide intermediate demand maintained the modest upward trend.
Sulfanilamide Prices in China in 2025
Chinese prices firmed from roughly USD 14.2/KG in Q1 2025 to USD 14.5/KG by Q4, a gain of 2.1%. Growing pharmaceutical sulfonamide intermediate export and domestic demand drove modest firming.
Sulfanilamide Prices in Germany in 2025
German prices firmed from about USD 25.2/KG in Q1 2025 to USD 25.6/KG by Q4, a gain of 1.6%. Consistent pharmaceutical intermediate and topical antibiotic demand and firm synthesis costs supported.
Sulfanilamide Prices in India in 2025
Indian prices firmed from roughly USD 19.5/KG in Q1 2025 to USD 19.8/KG by Q4, a gain of 1.5%. Growing pharmaceutical sulfonamide intermediate and topical antibiotic export demand drove firming.
How We Can Help
Expert Market Research: Your Source for Real-Time Sulfanilamide Price Intelligence
Expert Market Research tracks Sulfanilamide prices continuously across every major producing and consuming region. The team traces causation through aniline synthesis feedstock economics, sulfonamide pharmaceutical intermediate and topical antibiotic procurement cycles, and regional production capacity. Contact Expert Market Research today for Sulfanilamide pricing data, bespoke market analysis, and strategic procurement advisory.
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Key Questions Answered in the Report
Pharmaceutical synthesis intermediate as the parent compound and building block for sulfamethoxazole, sulfadiazine, sulfacetamide, and other sulfonamide antibiotic derivatives takes the largest share. Direct topical antibiotic use in burn wound and skin infection treatment formulations and applications in synthetic dye and agrochemical intermediate manufacturing also consume significant volumes globally.
The Q2 2026 average was USD 22.5/KG in the United States, USD 15.7/KG in China, USD 27.7/KG in Germany, and USD 21.4/KG in India. Germany remains the highest-priced market.
The global average rose from USD 18.54/KG in Q1 to about USD 19.65/KG in Q2, a gain of around 6.0%. Recovering pharmaceutical intermediate and topical antibiotic procurement and firmer aniline synthesis feedstock costs drove the H1 firming from the Q4 2025 correction.
Aniline and sulfonation synthesis feedstock cost moderation eased the production floor. Seasonal pharmaceutical intermediate and topical antibiotic procurement moderation reduced buying urgency before the H1 2026 recovery.
The global average is expected in the USD 19.80 to 22.20/KG range for H2 2026, with continued firming as synthesis feedstock costs stay elevated and pharmaceutical sulfonamide intermediate and topical antibiotic demand grows globally.
Germany sits highest on aniline and energy costs, the United States and India hold a firm middle on pharmaceutical and topical demand, and China prices lowest on domestic production capacity.
This report is updated monthly. For real-time pricing intelligence, contact the Expert Market Research team directly.
Prices respond mainly to aniline and sulfonation reagent synthesis feedstock costs, pharmaceutical sulfonamide intermediate procurement cycles, and topical antibiotic demand. Benzene feedstock and aniline prices are key upstream cost signals.
China holds the largest sulfanilamide production capacity, followed by India and Europe. Any aniline feedstock cost shift ripples across markets within one to two quarters.
Buyers can use quarterly trends and forecasts to time pharmaceutical sulfonamide intermediate contracts around synthesis cost cycles, build cover when aniline signals tighten, and monitor benzene feedstock prices as the primary upstream cost signal.
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