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Report Overview

The Australia pulmonary arterial hypertension drugs market was valued at USD 173.91 Million in 2025 and is expected to grow at a CAGR of 4.20%, reaching USD 262.42 Million by 2035. The market growth is supported by increasing adoption of advanced PAH therapies, including prostacyclin analogs and endothelin receptor antagonists. Growing awareness among healthcare providers and patients, along with government reimbursement policies, is boosting treatment accessibility. Ongoing clinical trials and research into novel therapies for early diagnosis and management are expected to enhance market growth during the forecast period.

Key Market Trends and Insights

  • Based on segment, prostacyclin and prostacyclin analogs held around 30% of the market share during the historical period.
  • By route of administration, the oral segment dominated the market during the historical period.
  • Hospital pharmacies are expected to witness the fastest growth during the forecast period.

Market Size and Forecast

  • Market Size (2025): USD 173.91 Million
  • Projected Market Size (2035): USD 262.42 Million
  • CAGR (2026-2035): 4.20%
2025

Base Year

2019-2025

Historical Period

2026-2035

Forecast Period

  • The growth in the market is driven by increasing pulmonary arterial hypertension prevalence, advancements in diagnostic capabilities, and rising adoption of targeted pharmacological treatments.

  • Several key trends in the market include the development of combination therapy approaches and sustained investment in novel drug classes.

  • The leading players in the market are accelerating growth through innovative product introductions, strategic partnerships, and enhanced treatment accessibility.

Compound Annual Growth Rate

4.2%

Value in USD Million

2026-2035


*this image is indicative*

Australia Pulmonary Arterial Hypertension Drugs Market Overview

Pulmonary arterial hypertension drugs are advanced therapeutic agents aimed at improving hemodynamic function and reducing disease progression by targeting vascular remodeling and pulmonary vasoconstriction pathways. The market is driven by increased disease awareness, improved diagnostics, and the adoption of innovative therapies. The market was valued at USD 173.91 Million in 2025, supported by strong healthcare infrastructure and government initiatives enhancing patient access to treatment. Rising investment in research and development is further expected to expand the therapeutic landscape in the coming years.

Australia Pulmonary Arterial Hypertension Drugs Market Growth Drivers

Rising Disease Prevalence to Drive the Market Expansion in Australia

The increasing prevalence of pulmonary arterial hypertension (PAH) is a key growth driver in the Australian market. According to Shuoshuo Wei et al. (2025), registry-based studies indicate notable geographic variations, with Central Australia recording a higher prevalence of 48 cases per million, compared to approximately 25 per million in the United States. The Global Burden of Diseases (GBD) study further reported in 2021 an age-standardized prevalence of 2.28 per 100,000 and a higher impact among women and elderly populations. This growing disease burden is anticipated to significantly boost demand for PAH drugs in Australia.

Australia Pulmonary Arterial Hypertension Drugs Market Trends

Some of the trends in the market include the growing use of combination therapies and the increasing adoption of advanced endothelin receptor antagonists.

Combination Therapies Driving Innovation in the Pulmonary Arterial Hypertension Drugs Market in Australia

The market is witnessing a growing trend toward fixed-dose combination therapies, aiming to improve treatment adherence and patient outcomes. In September 2024, a notable development was the approval of a macitentan and tadalafil combination tablet, offering a simplified once-daily regimen for eligible patients. Such advancements enhance convenience by replacing multiple pills with a single formulation, supporting long-term disease management. This shift toward combination therapies is expected to boost market value by addressing unmet needs and improving therapeutic efficiency.

Rising Adoption of Advanced Endothelin Receptor Antagonists to Boost Australia Pulmonary Arterial Hypertension Drugs Market Value

The increasing adoption of advanced endothelin receptor antagonists, driven by the need for effective long-term management of PAH and associated comorbidities, is a growing trend in the market. In September 2024, updated treatment information for Bosentan highlighted its role in addressing PAH related to conditions such as scleroderma, reinforcing its clinical relevance. Growing emphasis on early diagnosis, improved therapeutic monitoring, and the integration of targeted drug therapies is expected to significantly enhance the market’s growth trajectory in the coming years.

Australia Pulmonary Arterial Hypertension Drugs Market Share

Endothelin Receptor Antagonists Poised to Dominate Market Share by Drug Class

The market encompasses various drug classes, including endothelin receptor antagonists (ERAs), soluble guanylate cyclase (SGC) stimulators, phosphodiesterase Type 5 (PDE-5) inhibitors, prostacyclin and prostacyclin analogs, and others. Among these, ERAs are expected to lead the market, driven by their proven efficacy in improving exercise capacity, delaying disease progression, and their widespread adoption as a first-line therapy in clinical practice. Strong clinical evidence and expanding patient access further reinforce their dominant position in the market.

Leading Players in the Australia Pulmonary Arterial Hypertension Drugs Market

The key features of the market report comprise clinical trials analysis, funding and investment analysis, and strategic initiatives by the leading players. The major companies in the market are as follows:

Bayer AG

Bayer is the manufacturer of riociguat (Adempas®), a soluble guanylate cyclase stimulator that is approved in Australia for treating pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). Through its Australian subsidiary, Bayer participates in government subsidy schemes (e.g. PBS Highly Specialised Drugs) enabling access for PAH patients in specialist settings. Its role is as innovator and supplier of newer mechanism drugs that broaden the therapeutic options beyond traditional endothelin receptor antagonists and prostacyclins in Australia.

Teva Pharmaceuticals Industries Ltd.

Teva operates in Australia largely via its generic and specialty medicines business. In the PAH drugs market, Teva’s involvement comes mainly from supplying generic versions of PAH-agents (e.g. ambrisentan generics) that have been approved in Australia by the TGA. These generics help widen access by lowering cost and increasing treatment options under the Pharmaceutical Benefits Scheme.

Eli Lilly and Company

Eli Lilly is an innovator pharmaceutical company with involvement in PAH through supply of tadalafil (originally developed by Lilly) for PAH (often in combination therapy) and collaboration in clinical trials involving dual-therapy regimens. Although the specific PAH product branding and PBS subsidy may involve partners, Lilly plays a role in bringing forward therapies that combine its molecules (like tadalafil) as part of treatment guidelines in Australia.

GSK plc

GlaxoSmithKline (GSK) markets ambrisentan (Volibris®) in Australia, an endothelin receptor antagonist used to treat PAH in patients with WHO functional class II–IV symptoms. Ambrisentan has orphan drug designation in Australia, helping in its regulatory path. Through GSK’s involvement, Australian clinicians have access to non-prostanoid, oral ERA therapy, which is an important class in PAH management.

*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*

Other key players in the market include Pfizer Inc., Amgen Inc., and Novartis AG, among others.

Australia Pulmonary Arterial Hypertension Drugs Market Segmentation

The market report offers a detailed analysis of the market based on the following segments:

Market Breakup by Drug Class

  • Endothelin Receptor Antagonists
  • SGC Stimulators
  • PDE-5 Inhibitors
  • Prostacyclin and Prostacyclin Analogs

Market Breakup by Route of Administration

  • Oral
  • Parenteral
  • Others

Market Breakup by Type

  • Innovative
  • Generics

Market Breakup by Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Key Questions Answered in the Australia Pulmonary Arterial Hypertension Drugs Market Report

  • What was the Australia pulmonary arterial hypertension drugs market value in 2025?
  • What is the Australia pulmonary arterial hypertension drugs market forecast outlook for 2026-2035?
  • What are the major factors aiding the Australia pulmonary arterial hypertension drugs market demand?
  • How has the market performed so far, and how is it anticipated to perform in the coming years?
  • What are the market's major drivers, opportunities, and restraints?
  • What are the major Australia pulmonary arterial hypertension drugs market trends?
  • Which drug class is expected to dominate the market segment?
  • Which route of administration is projected to lead the market segment?
  • Which type is anticipated to drive the market segment?
  • Which distribution channel is expected to dominate the market segment?
  • Who are the key players involved in the Australia pulmonary arterial hypertension drugs market?
  • What are the current unmet needs and challenges in the market?
  • How are partnerships, collaborations, mergers, and acquisitions among the key market players shaping the market dynamics?

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Report Summary

Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

REPORT FEATURES DETAILS
Base Year 2025
Historical Period 2019-2025
Forecast Period 2026-2035
Scope of the Report

Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:

  • Drug Class
  • Route of Administration
  • Type
  • Distribution Channel
Breakup by Drug Class
  • Endothelin Receptor Antagonists
  • SGC Stimulators
  • PDE-5 Inhibitors
  • Prostacyclin & Prostacyclin Analogs
Breakup by Route of Administration
  • Oral
  • Parenteral
  • Others
Breakup by Type
  • Innovative
  • Generics
Breakup by Distribution Channel
  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies
Market Dynamics
  • Market Drivers and Constraints
  • SWOT Analysis
  • PESTEL Analysis
  • Porter’s Five Forces Model 
  • Key Demand Indicators
  • Key Price Indicators
  • Industry Events, Initiatives, and Trends 
  • Value Chain Analysis
Supplier Landscape
  • Market Structure
  • Company Profiles
    • Financial Analysis
    • Product Portfolio
    • Demographic Reach and Achievements
    • Company News and Developments
    • Certifications
Companies Covered
  • Bayer AG
  • Teva Pharmaceuticals Industries Ltd.
  • Eli Lilly and Company
  • GSK plc
  • Pfizer Inc.
  • Novartis AG
  • Amgen Inc.

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