The global bone void fillers market size attained a value of USD 3.19 billion in 2022 driven by increased launch of advanced products, increase in arthroplasty and trauma surgeries, growing geriatric population, and increase in sports injuries. The market is anticipated to grow at a CAGR of 6.8% during the forecast period of 2023-2031 to attain a value of USD 5.77 billion by 2031.
The defects may be surgically fashioned osseous defects or osseous defects created from injury to the bone, caused by trauma, infection (including osteomyelitis), disease, or related surgery. Further, growing number of total joint replacements (TJR) and infected TJR warrant revision surgeries. Thus, solutions like biodegradable, easy-to-use “press-fitting” antibiotic-releasing bone void filling (ABVF) putty offering efficient antibiotic release kinetics at the infection site and allowing efficient osseointegration are expected to drive market growth. North America, Europe and Asia Pacific are expected to be key markets.
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Bone grafting to augment skeletal healing is a common technique in surgical practice. However, morbidity and restricted availability associated with autografts, and the possibility of disease transmission, immunogenic response, and variable quality associated with allografts, have led to the use of several alternative materials, including calcium sulphate and calcium phosphate materials, and more complex materials containing allograft extracts, bone morphogenetic proteins, and other agents. Calcium sulphate is one of the simplest and most used synthetic bone graft material.
Leading companies offer advanced solutions that are expected to boost growth of global bone void fillers market. For example, Cerament bone void filler by Bonesupport is an injectable, mouldable and drillable synthetic bone void filler comprising 40% hydroxyapatite, 60% calcium sulphate and the radio-contrast agent iohexol. The unique ratio of hydroxyapatite and calcium sulphate is designed to enable Cerament to resorb at the same rate that bone forms. Calcium sulphate acts as a resorbable carrier for hydroxyapatite, and hydroxyapatite is highly osteoconductive, promoting bone ingrowth. The features of Cerament bone void filler make it appropriate for minimally invasive surgery and open procedures where bone remodelling is required. Features include: remodels into host bone within six to twelve months; injectable and flowable; added radiopacity; isothermic and not affected by room temperature; and easy to mix and use.
OSferion by Arthrex is an osteoconductive bone graft substitute and bone void filler comprising 100% beta-tricalcium phosphate (β-TCP). OSferion’s micro- and macroporous structure enables it to be resorbed and replaced by bone during the healing process. OSferion wedges are meant to be used in combination with the distal femoral and high tibial opening wedge osteotomy plates and screws to foster healing and offer added rigidity to the repair. The chamfered wedge design of the OSferion implants corresponds to the shape of the osteotomy and can be readily trimmed to size with the help of a rongeur.
Cytophil, Inc. offers Orthopedic β-Tricalcium Phosphate Product (β – TCP) synthetic bone void filler granulate meets the requirements of ASTM F1088. Its osteoconductive matrix directly bonds to bone, offering an excellent scaffold for bony infiltration. The granules have multidirectional porous structure similar to cancellous bone which provides a favourable structure for bony infiltration (approximately eighty percent porous). Its high surface microporosity enables wicking of fluids and bony deposition. Interconnected macroposity enables cellular mediation to help in new bone growth. Cellular activity on the highly porous surfaces of the granules allows resorption so that β – TCP is progressively replaced by new bone formation. Use of synthetic β – TCP eliminates the risk of disease transmission related to allografts (human tissue).
PRO-DENSE™ Graft by Wright Biologics is a synthetic biomaterial. It combines calcium sulphate with calcium phosphate; PRO-DENSE™ Graft has a triphasic resorption profile that offers a conducive environment for the direct deposition of bone leading to a slow-resorbing matrix that assists healing across the defect.
Calcigen® S Calcium Sulfate Bone Void Filler by Zimmer Bionet is designed to harden intraoperatively; Calcigen S provides an osteoconductive environment for bone growth. Product type includes biologics and bone grafting.
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By type, the global bone void fillers market is segmented into:
By form, the market is classified into:
By end use, the market is divided into:
By region, the market is segmented into:
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The report presents a detailed analysis of the following key players in the global bone void fillers market, looking into their capacity, and latest developments like capacity expansions, plant turnarounds, and mergers and acquisitions:
The EMR report gives an in-depth insight into the industry by providing a SWOT analysis as well as an analysis of Porter’s Five Forces model.
|Scope of the Report||
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
|Breakup by Type||
|Breakup by Form||
|Breakup by End User||
|Breakup by Region||
*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage – Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Global Bone Void Fillers Market Overview
3.1 Global Bone Void Fillers Market Historical Value (2016-2022)
3.2 Global Bone Void Fillers Market Forecast Value (2023-2031)
4 Global Bone Void Fillers Market Landscape
4.1 Global Bone Void Fillers Developers Landscape
4.1.1 Analysis by Year of Establishment
4.1.2 Analysis by Company Size
4.1.3 Analysis by Region
4.2 Global Bone Void Fillers Product Landscape
4.2.1 Analysis by Type
4.2.2 Analysis by Form
4.2.3 Analysis by End User
5 Global Bone Void Fillers Market Dynamics
5.1 Market Drivers and Constraints
5.2 SWOT Analysis
5.3 Porter’s Five Forces Model
5.4 Key Demand Indicators
5.5 Key Price Indicators
5.6 Industry Events, Initiatives, and Trends
5.7 Value Chain Analysis
6 Global Bone Void Fillers Market Segmentation
6.1 Global Bone Void Fillers Market by Type
6.1.1 Market Overview
6.1.2 Demineralised Bone Matrix
6.1.3 Collagen Matrix
6.1.4 Calcium Sulphate
6.1.5 Tri-Calcium Phosphate
6.2 Global Bone Void Fillers Market by Form
6.2.1 Market Overview
6.3 Global Bone Void Fillers Market by End User
6.3.1 Market Overview
6.3.3 Specialty Clinics
6.4 Global Bone Void Fillers Market by Region
6.4.1 Market Overview
6.4.2 North America
6.4.4 Asia Pacific
6.4.5 Latin America
6.4.6 Middle East and Africa
7 North America Bone Void Fillers Market
7.1 Market Share by Country
7.2 United States of America
8 Europe Bone Void Fillers Market
8.1 Market Share by Country
8.2 United Kingdom
9 Asia Pacific Bone Void Fillers Market
9.1 Market Share by Country
10 Latin America Bone Void Fillers Market
10.1 Market Share by Country
11 Middle East and Africa Bone Void Fillers Market
11.1 Market Share by Country
11.2 Saudi Arabia
11.3 United Arab Emirates
11.5 South Africa
12 Patent Analysis
12.1 Analysis by Type of Patent
12.2 Analysis by Publication year
12.3 Analysis by Issuing Authority
12.4 Analysis by Patent Age
12.5 Analysis by CPC Analysis
12.6 Analysis by Patent Valuation
12.7 Analysis by Key Players
13 Grants Analysis
13.1 Analysis by year
13.2 Analysis by Amount Awarded
13.3 Analysis by Issuing Authority
13.4 Analysis by Grant Application
13.5 Analysis by Funding Institute
13.6 Analysis by NIH Departments
13.7 Analysis by Recipient Organization
14 Funding Analysis
14.1 Analysis by Funding Instances
14.2 Analysis by Type of Funding
14.3 Analysis by Funding Amount
14.4 Analysis by Leading Players
14.5 Analysis by Leading Investors
14.6 Analysis by Geography
15 Partnership and Collaborations Analysis
15.1 Analysis by Partnership Instances
15.2 Analysis by Type of Partnership
15.3 Analysis by Leading Players
15.4 Analysis by Geography
16 Regulatory Framework
16.1 Regulatory Overview
16.1.1 US FDA
16.1.2 EU EMA
16.1.3 INDIA CDSCO
16.1.4 JAPAN PMDA
17 Supplier Landscape
17.1 Arthrex Inc.
17.1.1 Financial Analysis
17.1.2 Product Portfolio
17.1.3 Demographic Reach and Achievements
17.1.4 Mergers and Acquisitions
17.2 BONE SUPPORT AB
17.2.1 Financial Analysis
17.2.2 Product Portfolio
17.2.3 Demographic Reach and Achievements
17.2.4 Mergers and Acquisitions
17.3 Stryker Corporation
17.3.1 Financial Analysis
17.3.2 Product Portfolio
17.3.3 Demographic Reach and Achievements
17.3.4 Mergers and Acquisitions
17.4 Zimmer Biomet
17.4.1 Financial Analysis
17.4.2 Financial Portfolio
17.4.3 Demographic Reach and Achievements
17.4.4 Mergers and Acquisitions
17.5 Exactech, Inc.
17.5.1 Financial Analysis
17.5.2 Product Portfolio
17.5.3 Demographic Reach and Achievements
17.5.4 Mergers and Acquisitions
17.6 Baxter International Inc.
17.6.1 Financial Analysis
17.6.2 Product Portfolio
17.6.3 Demographic Reach and Achievements
17.6.4 Mergers and Acquisitions
17.7 depuy synthes companies
17.7.1 Financial Analysis
17.7.2 Product Portfolio
17.7.3 Demographic Reach and Achievements
17.7.4 Mergers and Acquisitions
17.8 Medtronic plc
17.8.1 Financial Analysis
17.8.2 Product Portfolio
17.8.3 Demographic Reach and Achievements
17.8.4 Mergers and Acquisitions
17.9 NuVasive Inc
17.9.1 Financial Analysis
17.9.2 Product Portfolio
17.9.3 Demographic Reach and Achievements
17.9.4 Mergers and Acquisitions
17.10 Orthofix Medical Inc
17.10.1 Financial Analysis
17.10.2 Product Portfolio
17.10.3 Demographic Reach and Achievements
17.10.4 Mergers and Acquisitions
17.11 Smith and Nephew plc
17.11.1 Financial Analysis
17.11.2 Product Portfolio
17.11.3 Demographic Reach and Achievements
17.11.4 Mergers and Acquisitions
17.12 Wright Medical Group Inc
17.12.1 Financial Analysis
17.12.2 Product Portfolio
17.12.3 Demographic Reach and Achievements
17.12.4 Mergers and Acquisitions
18 Global Bone Void Fillers Market - Distribution Model (Additional Insight)
18.2 Potential Distributors
18.3 Key Parameters for Distribution Partner Assessment
19 Key Opinion Leaders (KOL) Insights (Additional Insight)
20 Company Competitiveness Analysis (Additional Insight)
20.1 Very Small Companies
20.2 Small Companies
20.3 Mid-Sized Companies
20.4 Large Companies
20.5 Very Large Companies
21 Payment Methods (Additional Insight)
21.1 Government Funded
21.2 Private Insurance
*Additional insights provided are customisable as per client requirements.
In 2022, the global market of Bone Void Fillers attained a value of USD 3.19 billion.
The market is anticipated to grow at a CAGR of 6.8% during the forecast period of 2023-2031 to reach a value of USD 5.77 billion by 2031.
The major drivers of the market include the increased launch of advanced products, increase in arthroplasty and trauma surgeries, growing geriatric population, and increase in sports injuries.
The rising prevalence of bone-related diseases and rapid adoption of synthetic void fillers involving various material types are the key industry trends propelling the market's growth.
The major regions in the industry are North America, Latin America, the Middle East and Africa, Europe, and the Asia Pacific.
The various types of bone void fillers are demineralised bone matrix, collagen matrix, calcium sulphate, and tri-calcium phosphate, among others.
The different forms of bone void fillers in the market are gel, granules, paste, and putty, among others.
The end-uses of the market are hospitals and speciality clinics, among others.
The major players in the industry are Arthrex Inc., BONE SUPPORT AB, Stryker Corporation, Zimmer Biomet, and Exactech, Inc., among others.
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