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Cardiometabolic Disease Market

Cardiometabolic Disease Market Size, Share, Growth, Trends: By Disease Type: Chronic/Congestive Heart Failure, Hypertension, Type 2 Diabetes, Obesity, Others; By Treatment Type: ACE Inhibitors, Diuretics, Glucophage, Others; By Route of Administration; By End User; By Distribution Channel; Regional Analysis; Supplier Landscape; 2024-2032

Cardiometabolic Disease Market Outlook

The cardiometabolic disease market size was valued at USD 34.1 billion in 2023, driven by the rising incidence of risk factors such as sedentary lifestyle, obesity, and aging population across the 8 major markets. The market is expected to grow at a CAGR of 5.4% during the forecast period of 2024-2032, with the values likely to rise from USD 36 billion in 2024 to USD 54.8 billion by 2032.

 

Global Cardiometabolic Disease Market

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Cardiometabolic Disease Market Overview

Cardiometabolic illnesses are a group of metabolic diseases that can increase the risk of cardiovascular disease in people. These conditions include heart attack, stroke, insulin resistance, diabetes, and non-alcoholic fatty liver disease. The number of people experiencing one or more of these chronic preventable conditions is rising driven by factors such as smoking, unhealthy dietary habits, sedentary lifestyle, and excessive alcohol consumption.

 

The increasing incidence of risk factors is contributing to the growing prevalence of cardiometabolic diseases, which is expected to directly impact the cardiometabolic disease market demand. In the United States, a significant portion of the population is affected by these conditions. It is estimated that 11% of adults in the region are diagnosed with diabetes and around 10% are diagnosed with cardiovascular diseases such as stroke, coronary heart disease, and heart failure. The rising burden of these cardiometabolic conditions is likely to influence the demand for effective treatment solutions and advanced diagnostic methods.

 

The cardiometabolic disease market growth is driven by increased merger and acquisition initiatives among the key market players in order to share resources and expertise and accelerate the development of life-saving treatments for cardiometabolic diseases. In July 2023, Eli Lilly and Company announced that they had signed a definitive agreement to acquire Versanis Bio (a United States-based clinical-stage biopharmaceutical company) in a deal worth USD 1.925 billion to develop new therapeutics for the treatment of cardiometabolic diseases and improve patient outcomes. Versanis’ lead candidate bimagrumab has the potential to reduce fat mass without affecting muscle mass and is undergoing clinical trials in overweight and obese patients. This partnership aims to leverage Versanis’ expertise in activin biology and Lilly’s knowledge of incretin biology to create new medicines to combat cardiometabolic diseases. The rise in such strategic partnerships is expected to fuel market growth in the coming years.

 

One of the significant cardiometabolic disease market trends is the advancement in medical technology such as the rise in AI-driven drug development. In September 2023, Novo Nordisk A/S struck a deal worth USD 60 million and milestone payment amounting to USD 2.7 billion with a health technology company in the United States, Valo Health, to develop new treatments for cardiometabolic diseases by leveraging artificial intelligence. Under the agreement, the companies intend to utilize Valo’s Opal Computational Platform (for accessing real-world patient data), AI-enabled small molecule discovery, and the Biowire platform (to make heart tissue out of human cardiac cell samples). This indicates the growing adoption of artificial intelligence and machine learning platforms which are likely to boost the market value in the forecast period.

 

Global Cardiometabolic Disease Market by Segments

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Cardiometabolic Disease Market Segmentation

Market Breakup by Disease Type

  • Chronic/Congestive Heart Failure
  • Hypertension
  • Type 2 Diabetes
  • Obesity
  • Others

 

By disease type, the cardiometabolic disease market includes chronic/congestive heart failure, hypertension, type 2 diabetes, obesity, and other cardiometabolic conditions. This market segment covers a range of disorders affecting the cardiovascular and metabolic health.

 

Market Breakup by Treatment Type

  • ACE Inhibitors
  • Diuretics
  • Glucophage
  • Liposuction
  • Others

 

In terms of treatment type, options include ACE inhibitors, diuretics, glucophage, liposuction, and other medications or interventions to manage cardiometabolic diseases.

 

Market Breakup by Route of Administration

  • Oral
  • Intravenous
  • Others

 

By route of administration, the market comprises oral, intravenous, and other routes.

 

Market Breakup by End User

  • Hospitals
  • Clinics
  • Homecare Settings
  • Others

 

In terms of end users, the cardiometabolic disease market share includes hospitals, clinics, homecare settings, and other healthcare facilities where patients receive care for these conditions.

 

Market Breakup by Distribution Channel

  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy
  • Others

 

Distribution channels for cardiometabolic disease treatments include hospital pharmacies, retail pharmacies, online pharmacies, and others. This segment offers patients access to medications through a robust network of distribution channels.

 

Market Breakup by Region

  • United States
  • EU-4 and the United Kingdom
    • Germany
    • France
    • Italy
    • Spain
    • United Kingdom
  • Japan
  • India

 

Based on the region, the market includes the United States, EU-4 (Germany, France, Italy, Spain), and the United Kingdom, Japan, and India. North America is leading the market share, which can be attributed to the growing investment in research and development activities, high healthcare expenditure, and a well-developed healthcare sector in the region. Furthermore, the growing demand for advanced and innovative treatments to manage cardiometabolic diseases is likely to fuel the market in the coming years.

 

Global Cardiometabolic Disease Market by Region

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Cardiometabolic Disease Market: Competitor Landscape

The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:

 

  • biocrates life sciences ag
  • Eli Lilly and Company
  • Alnylam Pharmaceuticals, Inc.
  • Arrowhead Pharmaceuticals, Inc.
  • Dicerna Pharmaceuticals, Inc.
  • Cardax, Inc.
  • Novartis AG
  • Novo Nordisk A/S
  • Boehringer Ingelheim International GmbH
  • Kowa Company, Ltd
  • Allergan
  • AstraZeneca
  • Pfizer Inc.
  • Merck & Co., Inc.
  • Sanofi SA

 

Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.

 

Key Highlights of the Report

REPORT FEATURES DETAILS
Base Year 2023
Historical Period 2017-2023
Forecast Period 2024-2032
Scope of the Report

Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:

  • Disease Type
  • Treatment Type
  • Route of Administration
  • End User
  • Distribution Channel
  • Region
Breakup by Disease Type
  • Chronic/Congestive Heart Failure
  • Hypertension
  • Type 2 Diabetes
  • Obesity
  • Others
Breakup by Treatment Type
  • ACE Inhibitors
  • Diuretics
  • Glucophage
  • Liposuction 
  • Other
Breakup by Route of Administration
  • Oral
  • Intravenous
  • Others
Breakup by End User
  • Hospitals
  • Clinics
  • Homecare Settings
  • Others
Breakup by Distribution Channel
  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy
  • Others
Breakup by Region
  • United States
  • EU-4 and the United Kingdom
  • Japan
  • India
Market Dynamics
  • Market Drivers and Constraints
  • SWOT Analysis
  • Porter’s Five Forces Model 
  • Key Demand Indicators
  • Key Price Indicators
  • Industry Events, Initiatives, and Trends 
  • Value Chain Analysis
Supplier Landscape
  • Market Structure
  • Company Profiles
    • Financial Analysis
    • Product Portfolio
    • Demographic Reach and Achievements
    • Mergers and Acquisitions
    • Certifications
Companies Covered
  • biocrates life sciences ag
  • Eli Lilly and Company
  • Alnylam Pharmaceuticals, Inc.
  • Arrowhead Pharmaceuticals, Inc.
  • Dicerna Pharmaceuticals, Inc.
  • Cardax, Inc.
  • Novartis AG
  • Novo Nordisk A/S
  • Boehringer Ingelheim International GmbH
  • Kowa Company, Ltd
  • Allergan
  • AstraZeneca
  • Pfizer Inc.
  • Merck & Co., Inc.
  • Sanofi SA

 

Key Queries Solved in the Cardiometabolic Disease Market Report 

  • How has the market performed so far and how will it perform in the coming years?
  • What are the major trends influencing the market? 
  • What are the market's major drivers, opportunities, and restraints? 
  • What will be the effect of each driver, challenge, and opportunity on the market? 
  • Which regional market is expected to lead the market share in the forecast period? 
  • Which country is expected to experience expedited growth during the forecast period? 
  • How does the prevalence and incidence of cardiometabolic diseases affect the market landscape?
  • How does the rise in the geriatric population impact the cardiometabolic disease market size?
  • Which disease type will significantly influence the market growth?
  • Which treatment type is expected to dominate the market share? 
  • Which distribution channel is expected to have a high market value in the coming years?
  • Which end user is poised to lead the market share?
  • How will the ongoing clinical trials impact the market value during the forecast period? 
  • What are the factors driving regional disparities in the treatment and outcomes of cardiometabolic diseases?
  • What are the current unmet needs and challenges in the market?
  • How are partnerships, collaborations, along with mergers and acquisitions among the key market players shaping the market dynamics?

 

*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.

1    Preface
    1.1    Objectives of the Study
    1.2    Key Assumptions
    1.3    Report Coverage – Key Segmentation and Scope 
    1.4    Research Methodology
2    Executive Summary
3    Cardiometabolic Disease Market Overview – 8 Major Markets 

    3.1    Cardiometabolic Disease Market Historical Value (2017-2023) 
    3.2    Cardiometabolic Disease Market Forecast Value (2024-2032) 
4    Cardiometabolic Disease Overview 
    4.1    Guidelines and Stages
    4.2    Pathophysiology
    4.3    Screening and Diagnosis
    4.4    Treatment Pathway 
5    Patient Profile
    5.1    Patient Profile Overview
    5.2    Patient Psychology and Emotional Impact Factors
    5.3    Risk Assessment and Treatment Success Rate
6    Cardiometabolic Disease Epidemiology Scenario and Forecast – 8 Major Markets
    6.1    8MM Epidemiology Scenario Overview (2017-2032)
    6.2    United States Cardiometabolic Disease Epidemiology Scenario and Forecast (2017-2032)
    6.3    EU-4 and United Kingdom Cardiometabolic Disease Epidemiology Scenario and Forecast (2017-2032)
        6.3.1    Germany Cardiometabolic Disease Epidemiology Scenario and Forecast (2017-2032)
        6.3.2    France Cardiometabolic Disease Epidemiology Scenario and Forecast (2017-2032)
        6.3.3    Italy Cardiometabolic Disease Epidemiology Scenario and Forecast (2017-2032)
        6.3.4    Spain Cardiometabolic Disease Epidemiology Scenario and Forecast (2017-2032)
        6.3.5    United Kingdom Cardiometabolic Disease Epidemiology Scenario and Forecast (2017-2032)
    6.4    Japan Cardiometabolic Disease Epidemiology Scenario and Forecast (2017-2032) 
    6.5    India Cardiometabolic Disease Epidemiology Scenario and Forecast (2017-2032)
7    Cardiometabolic Disease Market Landscape – 8 Major Markets 
    7.1    Cardiometabolic Disease: Developers Landscape
        7.1.1    Analysis by Year of Establishment
        7.1.2    Analysis by Company Size
        7.1.3    Analysis by Region
    7.2    Cardiometabolic Disease: Product Landscape
        7.2.1    Analysis by Disease Type
        7.2.2    Analysis by Treatment Type
        7.2.3    Analysis by Route of Administration
8    Cardiometabolic Disease Challenges and Unmet Needs
    8.1    Treatment Pathway Challenges
    8.2    Compliance and Drop-Out Analysis
    8.3    Awareness and Prevention Gaps
9    Cost of Treatment
10    Cardiometabolic Disease Market Dynamics

    10.1    Market Drivers and Constraints
    10.2    SWOT Analysis
    10.3    Porter’s Five Forces Model
    10.4    Key Demand Indicators 
    10.5    Key Price Indicators
    10.6    Industry Events, Initiatives, and Trends  
    10.7    Value Chain Analysis
11    Cardiometabolic Disease Market Segmentation (2017-2032) - 8 Major Markets 
    11.1    Cardiometabolic Disease Market (2017-2032) by Disease Type
        11.1.1    Market Overview
        11.1.2    Chronic/Congestive Heart Failure
        11.1.3    Hypertension
        11.1.4    Type 2 Diabetes
        11.1.5    Obesity
        11.1.6    Others
    11.2    Cardiometabolic Disease Market (2017-2032) by Treatment Type
        11.2.1    Market Overview
        11.2.2    ACE Inhibitors
        11.2.3    Diuretics
        11.2.4    Glucophage
        11.2.5    Liposuction 
        11.2.6    Others
    11.3    Cardiometabolic Disease Market (2017-2032) by Route of Administration
        11.3.1    Market Overview 
        11.3.2    Oral
        11.3.3    Intravenous
        11.3.4    Others
    11.4    Cardiometabolic Disease Market (2017-2032) by End User
        11.4.1    Market Overview
        11.4.2    Hospitals
        11.4.3    Clinics
        11.4.4    Homecare Settings
        11.4.5    Others
    11.5    Cardiometabolic Disease Market (2017-2032) by Distribution Channel
        11.5.1    Market Overview
        11.5.2    Hospital Pharmacy
        11.5.3    Retail Pharmacy
        11.5.4    Online Pharmacy
        11.5.5    Others
    11.6    Cardiometabolic Disease Market (2017-2032) by Region
        11.6.1    Market Overview
        11.6.2    United States
        11.6.3    EU-4 and the United Kingdom
            11.6.3.1    Germany
            11.6.3.2    France
            11.6.3.3    Italy
            11.6.3.4    Spain
            11.6.3.5    United Kingdom
        11.6.4    Japan
        11.6.5    India 
12    United States Cardiometabolic Disease Market (2017-2032)
    12.1    United States Cardiometabolic Disease Market Historical Value (2017-2023) 
    12.2    United States Cardiometabolic Disease Market Forecast Value (2024-2032)
    12.3    United States Cardiometabolic Disease Market (2017-2032) by Disease Type
        12.3.1    Market Overview
        12.3.2    Chronic/Congestive Heart Failure
        12.3.3    Hypertension
        12.3.4    Type 2 Diabetes
        12.3.5    Obesity
        12.3.6    Others
    12.4    United States Cardiometabolic Disease Market (2017-2032) by Treatment Type
        12.4.1    Market Overview 
        12.4.2    ACE Inhibitors
        12.4.3    Diuretics
        12.4.4    Glucophage
        12.4.5    Liposuction Others
        12.4.6    Others
13    EU-4 and United Kingdom Cardiometabolic Disease Market (2017-2032)
    13.1    EU-4 and United Kingdom Cardiometabolic Disease Market Historical Value (2017-2023) 
    13.2    EU-4 and United Kingdom Cardiometabolic Disease Market Forecast Value (2024-2032)
    13.3    EU-4 and United Kingdom Cardiometabolic Disease Market (2017-2032) by Disease Type
        13.3.1    Market Overview
        13.3.2    Chronic/Congestive Heart Failure
        13.3.3    Hypertension
        13.3.4    Type 2 Diabetes
        13.3.5    Obesity
        13.3.6    Others
    13.4    EU-4 and United Kingdom Cardiometabolic Disease Market (2017-2032) by Treatment Type
        13.4.1    Market Overview 
        13.4.2    Market Overview 
        13.4.3    ACE Inhibitors
        13.4.4    Diuretics
        13.4.5    Glucophage
        13.4.6    Liposuction Others
        13.4.7    Others
14    Japan Cardiometabolic Disease Market
    14.1    Japan Cardiometabolic Disease Market Historical Value (2017-2023) 
    14.2    Japan Cardiometabolic Disease Market Forecast Value (2024-2032)
    14.3    Japan Cardiometabolic Disease Market (2017-2032) by Disease Type
        14.3.1    Market Overview
        14.3.2    Chronic/Congestive Heart Failure
        14.3.3    Hypertension
        14.3.4    Type 2 Diabetes
        14.3.5    Obesity
        14.3.6    Others
    14.4    Japan Cardiometabolic Disease Market (2017-2032) by Treatment Type
        14.4.1    Market Overview 
        14.4.2    Market Overview 
        14.4.3    ACE Inhibitors
        14.4.4    Diuretics
        14.4.5    Glucophage
        14.4.6    Liposuction Others
        14.4.7    Others
15    India Cardiometabolic Disease Market
    15.1    India Cardiometabolic Disease Market (2017-2032) Historical Value (2017-2023) 
    15.2    India Cardiometabolic Disease Market (2017-2032) Forecast Value (2024-2032)
    15.3    India Cardiometabolic Disease Market (2017-2032) by Disease Type
        15.3.1    Market Overview
        15.3.2    Chronic/Congestive Heart Failure
        15.3.3    Hypertension
        15.3.4    Type 2 Diabetes
        15.3.5    Obesity
        15.3.6    Others
    15.4    India Cardiometabolic Disease Market (2017-2032) by Treatment Type
        15.4.1    Market Overview 
        15.4.2    Market Overview 
        15.4.3    ACE Inhibitors
        15.4.4    Diuretics
        15.4.5    Glucophage
        15.4.6    Liposuction Others
        15.4.7    Others
16    Regulatory Framework
    16.1    Regulatory Overview
        16.1.1    US FDA
        16.1.2    EU EMA
        16.1.3    Japan PMDA
        16.1.4    Others
17    Patent Analysis
    17.1    Analysis by Type of Patent
    17.2    Analysis by Publication Year
    17.3    Analysis by Issuing Authority
    17.4    Analysis by Patent Age
    17.5    Analysis by CPC Analysis
    17.6    Analysis by Patent Valuation 
    17.7    Analysis by Key Players
18    Grants Analysis
    18.1    Analysis by Year
    18.2    Analysis by Amount Awarded
    18.3    Analysis by Issuing Authority
    18.4    Analysis by Grant Application
    18.5    Analysis by Funding Institute
    18.6    Analysis by NIH Departments
    18.7    Analysis by Recipient Organization 
19    Clinical Trials Analysis
    19.1    Analysis by Trial Registration Year
    19.2    Analysis by Trial Status
    19.3    Analysis by Trial Phase
    19.4    Analysis by Therapeutic Area
    19.5    Analysis by Geography
20    Funding and Investment Analysis
    20.1    Analysis by Funding Instances
    20.2    Analysis by Type of Funding
    20.3    Analysis by Funding Amount
    20.4    Analysis by Leading Players
    20.5    Analysis by Leading Investors
    20.6    Analysis by Geography
21    Partnership and Collaborations Analysis
    21.1    Analysis by Partnership Instances
    21.2    Analysis by Type of Partnership
    21.3    Analysis by Leading Players
    21.4    Analysis by Geography
22    Supplier Landscape
    22.1    Market Share by Top 5 Companies 
    22.2    biocrates life sciences ag
        22.2.1    Financial Analysis
        22.2.2    Product Portfolio
        22.2.3    Demographic Reach and Achievements
        22.2.4    Mergers and Acquisition
        22.2.5    Certifications
    22.3    Eli Lilly and Company
        22.3.1    Financial Analysis
        22.3.2    Product Portfolio
        22.3.3    Demographic Reach and Achievements
        22.3.4    Mergers and Acquisition
        22.3.5    Certifications
    22.4    Alnylam Pharmaceuticals, Inc.
        22.4.1    Financial Analysis
        22.4.2    Product Portfolio
        22.4.3    Demographic Reach and Achievements
        22.4.4    Mergers and Acquisition
        22.4.5    Certifications
    22.5    Arrowhead Pharmaceuticals, Inc.
        22.5.1    Financial Analysis
        22.5.2    Product Portfolio
        22.5.3    Demographic Reach and Achievements
        22.5.4    Mergers and Acquisition
        22.5.5    Certifications
    22.6    Dicerna Pharmaceuticals, Inc.
        22.6.1    Financial Analysis
        22.6.2    Product Portfolio
        22.6.3    Demographic Reach and Achievements
        22.6.4    Mergers and Acquisition
        22.6.5    Certifications
    22.7    Cardax, Inc.
        22.7.1    Financial Analysis
        22.7.2    Product Portfolio
        22.7.3    Demographic Reach and Achievements
        22.7.4    Mergers and Acquisition
        22.7.5    Certifications
    22.8    Novartis AG
        22.8.1    Financial Analysis
        22.8.2    Product Portfolio
        22.8.3    Demographic Reach and Achievements
        22.8.4    Mergers and Acquisition
        22.8.5    Certifications
    22.9    Novo Nordisk A/S
        22.9.1    Financial Analysis
        22.9.2    Product Portfolio
        22.9.3    Demographic Reach and Achievements
        22.9.4    Mergers and Acquisition
        22.9.5    Certifications
    22.10    Boehringer Ingelheim International GmbH
        22.10.1    Financial Analysis
        22.10.2    Product Portfolio
        22.10.3    Demographic Reach and Achievements
        22.10.4    Mergers and Acquisition
        22.10.5    Certifications
    22.11    Kowa Company, Ltd
        22.11.1    Financial Analysis
        22.11.2    Product Portfolio
        22.11.3    Demographic Reach and Achievements
        22.11.4    Mergers and Acquisition
        22.11.5    Certifications
    22.12    Allergan
        22.12.1    Financial Analysis
        22.12.2    Product Portfolio
        22.12.3    Demographic Reach and Achievements
        22.12.4    Mergers and Acquisition
        22.12.5    Certifications
    22.13    AstraZeneca
        22.13.1    Financial Analysis
        22.13.2    Product Portfolio
        22.13.3    Demographic Reach and Achievements
        22.13.4    Mergers and Acquisition
        22.13.5    Certifications
    22.14    Pfizer Inc.
        22.14.1    Financial Analysis
        22.14.2    Product Portfolio
        22.14.3    Demographic Reach and Achievements
        22.14.4    Mergers and Acquisition
        22.14.5    Certifications
    22.15    Merck & Co., Inc.
        22.15.1    Financial Analysis
        22.15.2    Product Portfolio
        22.15.3    Demographic Reach and Achievements
        22.15.4    Mergers and Acquisition
        22.15.5    Certifications
    22.16    Sanofi SA
        22.16.1    Financial Analysis
        22.16.2    Product Portfolio
        22.16.3    Demographic Reach and Achievements
        22.16.4    Mergers and Acquisition
        22.16.5    Certifications
23    Cardiometabolic Disease Treatment Drugs - Distribution Model (Additional Insight)
    23.1    Overview 
    23.2    Potential Distributors 
    23.3    Key Parameters for Distribution Partner Assessment 
24    Key Opinion  Leaders (KOL) Insights (Additional Insight)
25    Company Competitiveness Analysis (Additional Insight)

    25.1    Very Small Companies
    25.2    Small Companies
    25.3    Mid-Sized Companies
    25.4    Large Companies
    25.5    Very Large Companies
26    Payment Methods (Additional Insight)
    26.1    Government Funded
    26.2    Private Insurance
    26.3    Out-of-Pocket

 

*Additional insights provided are customisable as per client requirements.

 

* The coverage of the Market Landscape section depends on the data availability and may cover a minimum of 80% of the total market. The EMR team strives to make this section as comprehensive as possible.

Key Questions Answered in the Report

The market attained a value of about USD 34.1 billion in 2023 driven by the rising incidence of risk factors such as sedentary lifestyle, obesity, and aging population across the 8 major markets.

The market is anticipated to grow at a CAGR of 5.4% during the forecast period of 2024-2032, likely to reach a market value of USD 54.8 billion by 2032. 

The market demand is driven by the growing prevalence of cardiometabolic diseases and the rising advancements in medical technology.

One of the significant trends in the market is the increased merger and acquisition initiatives among the key market players. In July 2023 , Eli Lilly and Company signed a definitive agreement to acquire Versanis Bio in a deal worth USD 1.925 billion to develop new therapeutics to manage cardiometabolic diseases.

Based on the disease type, the market includes chronic/congestive heart failure, hypertension, type 2 diabetes, obesity, and other cardiometabolic conditions. 

Based on the treatment type, the market is segmented into ACE inhibitors, diuretics, glucophage, liposuction, and other medications.

By route of administration, the market comprises oral, intravenous, and other routes. 

Major end users of the market are hospitals, clinics, homecare settings, and other healthcare facilities.

Distribution channels in the market include hospital pharmacies, retail pharmacies, online pharmacies, and others.

The major regions of the market include the United States, EU-4 (Germany, France, Italy, Spain), and the United Kingdom, Japan, and India.

Key players involved in the market are biocrates life sciences ag, Eli Lilly and Company, Alnylam Pharmaceuticals, Inc., Arrowhead Pharmaceuticals, Inc., Dicerna Pharmaceuticals, Inc., Cardax, Inc., Novartis AG, Novo Nordisk A/S, Boehringer Ingelheim International GmbH, Kowa Company, Ltd., Allergan, AstraZeneca, Pfizer Inc., Merck & Co., Inc., and Sanofi SA.

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