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Chemotherapy Induced Neutropenia Market

Chemotherapy Induced Neutropenia Market Share, Forecast: By Drug Type: Colony-Stimulating Factors (CSFs), Granulocyte Colony-Stimulating Factor (G-CSF), Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF); By Application; By Distribution Channel; By End User; Regional Analysis; Supplier Landscape; 2024-2032

Chemotherapy Induced Neutropenia Market Outlook

The chemotherapy induced neutropenia market size is expected to grow at a CAGR of 4.3% during the forecast period of 2024-2032, driven by the rising prevalence of cancer along with the growing demand for effective neutropenia management solutions across the 8 major markets.

 

Chemotherapy Induced Neutropenia Market Overview

Chemotherapy is the treatment modality that is used to treat different types of cancers. Chemotherapy induced neutropenia is a common risk associated with cancer treatment where neutrophils (a type of white blood cells) have abnormally low counts, making patients susceptible to infections. The market is experiencing a rise in the volume of cancer patients receiving chemotherapy, with over 1 million people in the United States  undergoing the treatment annually. Consequently, it is projected to fuel the chemotherapy induced neutropenia demand in the forecast period.

 

The surge in the approval of treatment products by the health authorities is poised to support the market expansion. In November 2023 , Evive Biotech (a subsidiary of Yifan Pharmaceutical Co., Ltd.) and Acrotech Biopharma (a wholly owned subsidiary of Aurobindo Pharma USA, Inc.) announced the approval of Efbemalenograstim alfa, marketed under the brand name Ryzneuta, by the United States Food and Drug Administration (FDA) to treat chemotherapy induced neutropenia in adult patients with non-myeloid malignancies. The medication developed by Evive Biotech is the first innovative biologics proven to stimulate the production of neutrophils. Acrotech Biopharma will be responsible for the commercialization of the product in the United States. The penetration of such effective treatment options is anticipated to boost the chemotherapy induced neutropenia market growth.

 

The market is also driven by the increased acquisition and merger initiatives by the key market players to meet the clinical needs of the patients suffering from chemotherapy induced neutropenia. Moreover, the rising patient awareness and the advancement in the healthcare system will accelerate the market value in coming years.

 

Chemotherapy Induced Neutropenia Market Trends

Key Trends     Description
Advancements in Granulocyte Colony-Stimulating Factor (G-CSF) Therapies Recent advancements in G-CSF therapies include the development of longer-acting formulations and biosimilars, which offer patient convenience and potentially lower costs of treatment.
Increased Focus on Prophylactic Treatments There is a growing focus on the prophylactic administration of neutropenia management drugs to prevent the onset of neutropenia and its complications, rather than treating it after it occurs. 
Development of Personalized and Precision Medicine The field of personalized medicine is influencing the market by offering tailored neutropenia management strategies based on individual patient risk factors, genetic predispositions, and specific chemotherapy regimens.
Integration of Predictive Analytics and Artificial Intelligence in Patient Monitoring Technological advancements in predictive analytics and artificial intelligence (AI) are being explored for their potential to predict the risk and onset of neutropenia in chemotherapy patients. Such technologies could lead to earlier interventions and more precise management of neutropenia.

 

Chemotherapy Induced Neutropenia Market Segmentation

Market Breakup by Drug Type

  • Colony-Stimulating Factors (CSFs)
  • Granulocyte Colony-Stimulating Factor (G-CSF)
  • Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)

 

Based on drug types, the market is segmented into colony-stimulating factors (CSFs), granulocyte colony-stimulating factor (G-CSF), and granulocyte-macrophage colony-stimulating factor (GM-CSF). These drugs stimulate the production of white blood cells to prevent or treat neutropenia.

 

Market Breakup by Application

  • Breast Cancer
  • Lung Cancer
  • Colorectal Cancer
  • Ovarian Cancer
  • Others

 

The chemotherapy induced neutropenia market report includes segmentation based on application as well. It includes breast cancer, lung cancer, colorectal cancer, ovarian cancer, and others. This market segment represents different types of cancers for which chemotherapy induced neutropenia treatments are utilized to manage or prevent complications.

 

Market Breakup by Distribution Channel

  • Online Pharmacies
  • Retail Pharmacies
  • Hospital Pharmacies
  • Others

 

Distribution channels in the market are online pharmacies, retail pharmacies, hospital pharmacies, and others. The robust network of these channels caters to the diverse needs of the patients and contributes to the chemotherapy induced neutropenia market share.

 

Market Breakup by End User

  • Cancer Research Institutes
  • Hospitals
  • Clinics
  • Others

 

End users of the market are cancer research institutes, hospitals, clinics, and other healthcare facilities.

 

Market Breakup by Region

  • United States
  • EU-4 and the United Kingdom
    • Germany
    • France
    • Italy
    • Spain
    • United Kingdom
  • Japan
  • China

 

Based on the region, the market includes the United States, EU-4 (Germany, France, Italy, Spain), United Kingdom, Japan, and China. North America dominates the market share which can be attributed to the high prevalence and incidence rates of cancer in the region. Furthermore, the presence of a well-established healthcare system also supports market growth in the market.

 

Chemotherapy Induced Neutropenia Market: Competitor Landscape

The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:

 

  • Novartis AG
  • Lupin Limited
  • Ligand Pharmaceuticals
  • Biogenomics Limited
  • Baxter International
  • Apotex
  • Evive Biotech
  • BeyondSpring Pharmaceuticals
  • Myelo therapeutics
  • Cellerant Therapeutics
  • Aileron Therapeutics
  • Enzychem Lifesciences Corporation
  • Spectrum Pharmaceuticals
  • G1 Therapeutics
  • Teva B.V

 

Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.

 

Key Highlights of the Report

REPORT FEATURES DETAILS
Base Year 2023
Historical Period 2017-2023
Forecast Period 2024-2032
Scope of the Report

Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:

  • Drug Type
  • Application
  • Distribution Channel
  • End User
  • Region
Breakup by Drug Type
  • Colony-Stimulating Factors (CSFs)
  • Granulocyte Colony-Stimulating Factor (G-CSF)
  • Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
Breakup by Application
  • Breast Cancer
  • Lung Cancer
  • Colorectal Cancer
  • Ovarian Cancer
  • Others
Breakup by Distribution Channel
  • Online Pharmacies
  • Retail Pharmacies
  • Hospital Pharmacies
  • Others
Breakup by End User
  • Cancer Research Institutes
  • Hospitals
  • Clinics
  • Others
Breakup by Region
  • United States
  • EU-4 and the United Kingdom
  • Japan
  • China
Market Dynamics
  • Market Drivers and Constraints
  • SWOT Analysis
  • Porter’s Five Forces Model 
  • Key Demand Indicators
  • Key Price Indicators
  • Industry Events, Initiatives, and Trends 
  • Value Chain Analysis
Supplier Landscape
  • Market Structure
  • Company Profiles
    • Financial Analysis
    • Product Portfolio
    • Demographic Reach and Achievements
    • Mergers and Acquisitions
    • Certifications
Companies Covered
  • Novartis AG
  • Lupin Limited
  • Ligand Pharmaceuticals
  • Biogenomics Limited
  • Baxter International
  • Apotex
  • Evive Biotech
  • BeyondSpring Pharmaceuticals
  • Myelo Therapeutics
  • Cellerant Therapeutics
  • Aileron Therapeutics
  • Enzychem Lifesciences Corporation
  • Spectrum Pharmaceuticals
  • G1 Therapeutics
  • Teva B.V

 

Key Queries Solved in the Chemotherapy Induced Neutropenia Market Report

  • How has the chemotherapy induced neutropenia market performed so far and how will it perform in the coming years?
  • What are the major market trends influencing the market? 
  • What are the market's major drivers, opportunities, and restraints? 
  • Which regional market is expected to lead the market share in the forecast period? 
  • Which country is expected to experience expedited growth during the forecast period? 
  • How does the prevalence and incidence of cancer affect the market landscape?
  • How does the rising volume of chemotherapy treatments impact the chemotherapy induced neutropenia market value?
  • Which drug type of chemotherapy induced neutropenia will dominate the market share? 
  • Which application is expected to have a high market value in the coming years?
  • Which end user will contribute significantly to the market segment?
  • How will the ongoing clinical trials impact the market value during the forecast period? 
  • What are the current unmet needs and challenges in the market?
  • How are partnerships, collaborations, and mergers & acquisitions among the key market players shaping the market dynamics?

 

*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.

1    Preface
    1.1    Objectives of the Study
    1.2    Key Assumptions 
    1.3    Report Coverage – Key Segmentation and Scope  
    1.4    Research Methodology
2    Executive Summary
3    Chemotherapy Induced Neutropenia Market Overview – 8 Major Markets 

    3.1    Chemotherapy Induced Neutropenia Market Historical Value (2017-2023) 
    3.2    Chemotherapy Induced Neutropenia Market Forecast Value (2024-2032)
4     Chemotherapy Induced Neutropenia Overview 
    4.1    Guidelines and Stages
    4.2    Pathophysiology
    4.3    Screening and Diagnosis
    4.4    Therapy Pathway 
5    Patient Profile
    5.1    Patient Profile Overview 
    5.2    Patient Psychology and Emotional Impact Factors
    5.3    Risk Assessment and Therapy Success Rate
6    Chemotherapy Induced Neutropenia Epidemiology Analysis-8 Major Markets
    6.1    8MM Epidemiology Scenario Overview (2017-2032)
    6.2    United States Chemotherapy Induced Neutropenia Epidemiology Scenario and Forecast (2017-2032)
    6.3    EU-4 and United Kingdom Chemotherapy Induced Neutropenia Epidemiology Scenario and Forecast (2017-2032)
        6.3.1    Germany Chemotherapy Induced Neutropenia Epidemiology Scenario and Forecast (2017-2032)
        6.3.2    France Chemotherapy Induced Neutropenia Epidemiology Scenario and Forecast (2017-2032)
        6.3.3    Italy Chemotherapy Induced Neutropenia Epidemiology Scenario and Forecast (2017-2032)
        6.3.4    Spain Chemotherapy Induced Neutropenia Epidemiology Scenario and Forecast (2017-2032)
        6.3.5    United Kingdom Chemotherapy Induced Neutropenia Epidemiology Scenario and Forecast (2017-2032)
    6.4    Japan Chemotherapy Induced Neutropenia Epidemiology Scenario and Forecast (2017-2032)
    6.5    China Chemotherapy Induced Neutropenia Epidemiology Scenario and Forecast (2017-2032)
7    Chemotherapy Induced Neutropenia Market Landscape*- 8 Major Markets
    7.1     Chemotherapy Induced Neutropenia Developers Landscape
        7.1.1    Analysis by Year of Establishment
        7.1.2    Analysis by Company Size
        7.1.3    Analysis by Region
    7.2     Chemotherapy Induced Neutropenia Product Landscape
        7.2.1    Analysis by Drug Type
        7.2.2    Analysis by Application
8     Chemotherapy Induced Neutropenia Treatment Challenges and Unmet Needs
    8.1    Treatment Pathway Challenges
    8.2    Compliance and Drop-Out Analysis
    8.3    Awareness and Prevention Gaps
9    Cost of Treatment
10     Chemotherapy Induced Neutropenia Market Dynamics

    10.1    Market Drivers and Constraints
    10.2    SWOT Analysis
        10.2.1    Strengths
        10.2.2    Weaknesses
        10.2.3    Opportunities
        10.2.4    Threats
    10.3    Porter’s Five Forces Model
        10.3.1    Bargaining Power of Suppliers
        10.3.2    Bargaining Power of Buyers
        10.3.3    Threat of New Entrants
        10.3.4    Threat of Substitutes
        10.3.5    Degree of Rivalry
    10.4    Porter’s Five Forces Model 
    10.5    Key Demand Indicators
    10.6    Key Price Indicators
    10.7    Industry Events, Initiatives, and Trends 
    10.8    Value Chain Analysis
11     Chemotherapy Induced Neutropenia Market Segmentation (2017-2032) - 8 Major Markets
    11.1    Chemotherapy Induced Neutropenia Market (2017-2032) by Drug Type
        11.1.1    Market Overview
        11.1.2    Colony-Stimulating Factors (CSFs)
        11.1.3    Granulocyte Colony-Stimulating Factor (G-CSF)
        11.1.4    Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
    11.2    Chemotherapy Induced Neutropenia Market (2017-2032) by Application
        11.2.1    Market Overview
        11.2.2    Breast Cancer
        11.2.3    Lung Cancer
        11.2.4    Colorectal Cancer
        11.2.5    Ovarian Cancer
        11.2.6    Others
    11.3      Chemotherapy Induced Neutropenia Market (2017-2032) by Distribution Channel
        11.3.1    Market Overview 
        11.3.2    Online Pharmacies
        11.3.3    Retail Pharmacies
        11.3.4    Hospital Pharmacies
        11.3.5    Others
    11.4    Chemotherapy Induced Neutropenia Market (2017-2032) by End User
        11.4.1    Market Overview 
        11.4.2    Cancer Research Institutes
        11.4.3    Hospitals
        11.4.4    Clinics
        11.4.5    Others
    11.5    Chemotherapy Induced Neutropenia Market (2017-2032) by Region
        11.5.1    Market Overview
        11.5.2    United States
        11.5.3    EU-4 and the United Kingdom
            11.5.3.1    Germany
            11.5.3.2    France
            11.5.3.3    Italy
            11.5.3.4    Spain
            11.5.3.5    United Kingdom    
        11.5.4    Japan
        11.5.5    China
12    United States Chemotherapy Induced Neutropenia Market (2017-2032)
    12.1    United States Chemotherapy Induced Neutropenia Market Historical Value (2017-2023) 
    12.2    United States Chemotherapy Induced Neutropenia Market Forecast Value (2024-2032)
    12.3    United States Chemotherapy Induced Neutropenia Market (2017-2032) by Drug Type
        12.3.1    Market Overview
        12.3.2    Colony-Stimulating Factors (CSFs)
        12.3.3    Granulocyte Colony-Stimulating Factor (G-CSF)
        12.3.4    Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
    12.4    United States Chemotherapy Induced Neutropenia Market (2017-2032) by Application
        12.4.1    Market Overview
        12.4.2    Breast Cancer
        12.4.3    Lung Cancer
        12.4.4    Colorectal Cancer
        12.4.5    Ovarian Cancer
        12.4.6    Others
13    EU-4 and United Kingdom Chemotherapy Induced Neutropenia Market (2017-2032)
    13.1    EU-4 and United Kingdom Chemotherapy Induced Neutropenia Market Historical Value (2017-2023) 
    13.2    EU-4 and United Kingdom Chemotherapy Induced Neutropenia Market Forecast Value (2024-2032)
    13.3    EU-4 and United Kingdom Chemotherapy Induced Neutropenia Market (2017-2032) by Drug Type
        13.3.1    Market Overview
        13.3.2    Colony-Stimulating Factors (CSFs)
        13.3.3    Granulocyte Colony-Stimulating Factor (G-CSF)
        13.3.4    Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
    13.4    EU-4 and United Kingdom Chemotherapy Induced Neutropenia Market (2017-2032) by Application
        13.4.1    Market Overview
        13.4.2    Breast Cancer
        13.4.3    Lung Cancer
        13.4.4    Colorectal Cancer
        13.4.5    Ovarian Cancer
        13.4.6    Others
14    Japan Chemotherapy Induced Neutropenia Market (2017-2032)
    14.1    Japan Chemotherapy Induced Neutropenia Market Historical Value (2017-2023) 
    14.2    Japan Chemotherapy Induced Neutropenia Market Forecast Value (2024-2032)
    14.3    Japan Chemotherapy Induced Neutropenia Market (2017-2032) by Drug Type
        14.3.1    Market Overview
        14.3.2    Colony-Stimulating Factors (CSFs)
        14.3.3    Granulocyte Colony-Stimulating Factor (G-CSF)
        14.3.4    Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
    14.4    Japan Chemotherapy Induced Neutropenia Market (2017-2032) by Application
        14.4.1    Market Overview
        14.4.2    Breast Cancer
        14.4.3    Lung Cancer
        14.4.4    Colorectal Cancer
        14.4.5    Ovarian Cancer
        14.4.6    Others
15    China Chemotherapy Induced Neutropenia Market (2017-2032)
    15.1    China Chemotherapy Induced Neutropenia Market Historical Value (2017-2023) 
    15.2    China Chemotherapy Induced Neutropenia Market Forecast Value (2024-2032)
    15.3    China Chemotherapy Induced Neutropenia Market (2017-2032) by Drug Type
        15.3.1    Market Overview
        15.3.2    Colony-Stimulating Factors (CSFs)
        15.3.3    Granulocyte Colony-Stimulating Factor (G-CSF)
        15.3.4    Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
    15.4    China Chemotherapy Induced Neutropenia Market (2017-2032) by Application
        15.4.1    Market Overview
        15.4.2    Breast Cancer
        15.4.3    Lung Cancer
        15.4.4    Colorectal Cancer
        15.4.5    Ovarian Cancer
        15.4.6    Others
16    Regulatory Framework
    16.1    Regulatory Overview
        16.1.1    US FDA
        16.1.2    EU EMA
        16.1.3    Japan PMDA
        16.1.4    Others
17    Patent Analysis
    17.1    Analysis by Type of Patent 
    17.2    Analysis by Publication Year
    17.3    Analysis by Issuing Authority
    17.4    Analysis by Patent Age
    17.5    Analysis by CPC Analysis
    17.6    Analysis by Patent Valuation 
    17.7    Analysis by Key Players
18    Grants Analysis
    18.1    Analysis by Year 
    18.2    Analysis by Amount Awarded
    18.3    Analysis by Issuing Authority
    18.4    Analysis by Grant Application
    18.5    Analysis by Funding Institute
    18.6    Analysis by NIH Departments
    18.7    Analysis by Recipient Organization 
19    Clinical Trials Analysis
    19.1    Analysis by Trial Registration Year 
    19.2    Analysis by Trial Status
    19.3    Analysis by Trial Phase
    19.4    Analysis by Therapeutic Area
    19.5    Analysis by Geography
20    Funding Analysis
    20.1    Analysis by Funding Instances 
    20.2    Analysis by Type of Funding
    20.3    Analysis by Funding Amount
    20.4    Analysis by Leading Players
    20.5    Analysis by Leading Investors
    20.6    Analysis by Geography
21    Partnership and Collaborations Analysis
    21.1    Analysis by Partnership Instances 
    21.2    Analysis by Type of Partnership
    21.3    Analysis by Leading Players
    21.4    Analysis by Geography
22    Supplier Landscape
    22.1     Novartis AG
        22.1.1    Financial Analysis
        22.1.2    Product Portfolio
        22.1.3    Demographic Reach and Achievements
        22.1.4    Mergers and Acquisition
        22.1.5    Certifications
    22.2     Lupin Limited
        22.2.1    Financial Analysis
        22.2.2    Product Portfolio
        22.2.3    Demographic Reach and Achievements
        22.2.4    Mergers and Acquisition
        22.2.5    Certifications
    22.3    Ligand Pharmaceuticals
        22.3.1    Financial Analysis
        22.3.2    Product Portfolio
        22.3.3    Demographic Reach and Achievements
        22.3.4    Mergers and Acquisition
        22.3.5    Certifications
    22.4    Biogenomics Limited
        22.4.1    Financial Analysis
        22.4.2    Product Portfolio
        22.4.3    Demographic Reach and Achievements
        22.4.4    Mergers and Acquisition
        22.4.5    Certifications
    22.5     Baxter International
        22.5.1    Financial Analysis
        22.5.2    Product Portfolio
        22.5.3    Demographic Reach and Achievements
        22.5.4    Mergers and Acquisition
        22.5.5    Certifications
    22.6    Apotex
        22.6.1    Financial Analysis
        22.6.2    Product Portfolio
        22.6.3    Demographic Reach and Achievements
        22.6.4    Mergers and Acquisition
        22.6.5    Certifications
    22.7     Evive Biotech
        22.7.1    Financial Analysis
        22.7.2    Product Portfolio
        22.7.3    Demographic Reach and Achievements
        22.7.4    Mergers and Acquisition
        22.7.5    Certifications
    22.8     BeyondSpring Pharmaceuticals
        22.8.1    Financial Analysis
        22.8.2    Product Portfolio
        22.8.3    Demographic Reach and Achievements
        22.8.4    Mergers and Acquisition
        22.8.5    Certifications
    22.9    Myelo Therapeutics
        22.9.1    Financial Analysis
        22.9.2    Product Portfolio
        22.9.3    Demographic Reach and Achievements
        22.9.4    Mergers and Acquisition
        22.9.5    Certifications
    22.10    Cellerant Therapeutics
        22.10.1    Financial Analysis
        22.10.2    Product Portfolio
        22.10.3    Demographic Reach and Achievements
        22.10.4    Mergers and Acquisition
        22.10.5    Certifications
    22.11    Aileron Therapeutics
        22.11.1    Financial Analysis
        22.11.2    Product Portfolio
        22.11.3    Demographic Reach and Achievements
        22.11.4    Mergers and Acquisition
        22.11.5    Certifications
    22.12    Enzychem Lifesciences Corporation
        22.12.1    Financial Analysis
        22.12.2    Product Portfolio
        22.12.3    Demographic Reach and Achievements
        22.12.4    Mergers and Acquisition
        22.12.5    Certifications
    22.13    Spectrum Pharmaceuticals
        22.13.1    Financial Analysis
        22.13.2    Product Portfolio
        22.13.3    Demographic Reach and Achievements
        22.13.4    Mergers and Acquisition
        22.13.5    Certifications
    22.14    G1 Therapeutics
        22.14.1    Financial Analysis
        22.14.2    Product Portfolio
        22.14.3    Demographic Reach and Achievements
        22.14.4    Mergers and Acquisition
        22.14.5    Certifications
    22.15    Teva B.V
        22.15.1    Financial Analysis
        22.15.2    Product Portfolio
        22.15.3    Demographic Reach and Achievements
        22.15.4    Mergers and Acquisition
        22.15.5    Certifications
23     Chemotherapy Induced Neutropenia Market - Distribution Model (Additional Insight)
    23.1    Overview 
    23.2    Potential Distributors 
    23.3    Key Parameters for Distribution Partner Assessment 
24    Key Opinion Leaders (KOL) Insights (Additional Insight)
25    Company Competitiveness Analysis (Additional Insight)

    25.1    Very Small Companies
    25.2    Small Companies
    25.3    Mid-Sized Companies
    25.4    Large Companies
    25.5    Very Large Companies
26    Payment Methods (Additional Insight)
    26.1    Government Funded
    26.2    Private Insurance
    26.3    Out-of-Pocket

 

*Additional insights provided are customisable as per client requirements.

 

* The coverage of the Market Landscape section depends on the data availability and may cover a minimum of 80% of the total market. The EMR team strives to make this section as comprehensive as possible.

Key Questions Answered in the Report

The market is anticipated to grow at a CAGR of 4.3% during the forecast period of 2024-2032, driven by the rising prevalence of cancer along with the growing demand for effective neutropenia management solutions across the 8 major markets.

The market demand is driven by rising patient awareness and investments to bring  advancements in the healthcare system.

One of the significant trends in the market is the surge in the approval of treatment products by the health authorities. In November 2023 , Evive and Acrotech Biopharma announced the approval of Ryzneuta by the United States Food and Drug Administration (FDA) to treat chemotherapy induced neutropenia in adult patients with non-myeloid malignancies.

Based on the drug type, the market is segmented into colony-stimulating factors (CSFs), granulocyte colony-stimulating factor (G-CSF), and granulocyte-macrophage colony-stimulating factor (GM-CSF). 

Major end users of the market are cancer research institutes, hospitals, clinics, and other healthcare facilities.

Distribution channels in the market include online pharmacies, retail pharmacies, hospital pharmacies, and others.

The market is segmented by application into breast cancer, lung cancer, colorectal cancer, ovarian cancer, among others. 

The major regions of the market include the United States, EU-4 (Germany, France, Italy, Spain), United Kingdom, Japan, and China.

Key players involved in the market are Novartis AG, Lupin Limited, Ligand Pharmaceuticals, Biogenomics Limited, Baxter International, Apotex, Evive Biotech, BeyondSpring Pharmaceuticals, Myelo Therapeutics, Cellerant Therapeutics, Aileron Therapeutics, Enzychem Lifesciences Corporation, Spectrum Pharmaceuticals, G1 Therapeutics, and Teva B.V.

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