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The fungal infections market was valued at USD 8.55 Billion in 2025 and is expected to grow at a CAGR of 3.50%, reaching USD 12.06 Billion by 2035. The market growth is driven by the rising prevalence of invasive fungal infections and growing immunocompromised populations across the 8 major markets.
Base Year
Historical Period
Forecast Period
Climate change accelerating the spread of fungal pathogens is expected to increase demand for antifungal therapies and diagnostics globally.
F2G’s USD 100 million investment in late-stage trials of olorofim will drive pipeline development and strengthen antifungal market growth.
Baselea Pharmaceutica’s Phase 3 trial of fosmanogepix and new antifungal approvals are anticipated to enhance adoption and elevate market valuation.
Compound Annual Growth Rate
3.5%
Value in USD Billion
2026-2035
*this image is indicative*
The market is witnessing significant growth, driven by the rising prevalence of invasive and superficial fungal diseases. Increasing numbers of immunocompromised patients, including those with cancer, HIV, and organ transplants, are fueling demand for advanced antifungal therapies and diagnostics. Market expansion is supported by strategic investments, ongoing clinical trials, and regulatory approvals of novel antifungal drugs. Furthermore, global health initiatives emphasizing early detection, improved surveillance, and rapid diagnostic deployment are encouraging wider adoption, fostering innovation, and strengthening the overall growth trajectory of the fungal infections market worldwide. The market is expected to grow at a CAGR of 3.50% during the forecast period of 2026-2035 and attain a market value of USD 12.06 Billion by 2035.
Climate Change and Rising Prevalence to Drive the Fungal Infections Market Growth Substantially
The increasing immunocompromised populations and growing awareness of invasive fungal diseases are major market drivers. For instance, in May 2025, research highlighted that climate change is accelerating the spread of dangerous fungal pathogens, particularly Aspergillus species, into northern regions of Europe, Asia, and the Americas. With approximately 6.5 million people affected annually, causing 3.8 million deaths, the rising incidence of infections like aspergillosis is expected to fuel demand for antifungal therapies, diagnostics, and monitoring solutions, significantly boosting the market during the forecast period.
Major market trends include rising prevalence, strategic investments, clinical trials, and health initiatives.
Rising Prevalence Driving Global Market Growth
The global fungal infections burden is increasing, with 6.5 million people affected annually, resulting in 3.8 million deaths and 2.5 million cases directly caused by fungal pathogens. This high prevalence is propelling demand for effective antifungal therapies and diagnostics, prompting healthcare providers and governments to prioritize disease management. The growing patient pool, combined with the rise of immunocompromised populations, is expected to drive market expansion, stimulating investment in research, drug development, and advanced treatment solutions worldwide.
Strategic Investments Accelerating Fungal Infections Market Growth
For instance, in September 2024, antifungal drug developer F2G raised USD100 million to fund late-stage global trials of olorofim, targeting resistant invasive fungal infections. Such substantial investments highlight investor confidence in the antifungal segment and facilitate accelerated development pipelines. Increased funding allows faster regulatory submissions, global trials, and potential commercialization, which is expected to strengthen the fungal infections market by introducing innovative treatments to address high mortality and unmet patient needs during the forecast period.
Surge in Clinical Trials and Drug Launches to Meet Rising Fungal Infections Market Demand
In July 2025, Baselea Pharmaceutica initiated a Phase 3 trial of fosmanogepix for invasive mold infections. Combined with ongoing approvals like Rezafungin, these trials represent significant pipeline expansion in the antifungal market. New drug candidates with improved efficacy, oral/IV options, and resistance coverage are expected to increase treatment adoption, enhance patient outcomes, and elevate market valuation. Continued innovation is a major driver for market growth, attracting attention from healthcare providers, payers, and investors globally.
Global Health Initiatives Boosting Market Penetration
In April 2025, the World Health Organization published its first reports on fungal infection diagnostics and treatments, highlighting critical gaps and calling for increased R&D, surveillance, and rapid diagnostic deployment. These initiatives promote market penetration, especially in low- and middle-income countries, where prevalence is highest. Public health focus on early detection and management drives demand for both diagnostics and antifungal therapies, supporting long-term expansion of the global fungal infections market and encouraging innovation across treatment and monitoring solutions.
Hospital Pharmacies to Lead the Market by Distribution Channel
The hospital pharmacies segment held a dominant share of the market in the historical period, driven by high patient inflow for invasive and severe fungal infections requiring immediate and specialized care. Hospitals serve as primary centers for diagnosis, treatment, and administration of antifungal therapies, including intravenous formulations. The presence of advanced laboratory facilities, trained healthcare professionals, and robust procurement systems further reinforces this segment’s leadership. Additionally, increased hospital admissions of immunocompromised patients continue to support sustained growth and higher market share for hospital pharmacies.
North America dominates the fungal infections market with a 42% share, driven by a substantial patient population affected by fungal diseases such as candidiasis, aspergillosis, and cryptococcosis. High prevalence of immunocompromised individuals, including cancer, HIV, and transplant patients, is further fueling demand for advanced antifungal therapies and diagnostic tools. Additionally, the region benefits from robust healthcare infrastructure, strong R&D investments, and rapid adoption of innovative antifungal drugs. These factors collectively strengthen North America’s leadership position, while Europe and Asia-Pacific show growing potential due to increasing awareness, healthcare access, and emerging treatment options.
The key features of the market report comprise clinical trials analysis, patent analysis, funding and investment analysis, and strategic initiatives by the leading players. The major companies in the market are as follows:
Headquartered in Basel, Switzerland, F. Hoffmann-La Roche Ltd., established in 1896, is a global leader in diagnostics and pharmaceuticals. In the fungal infections market, Roche offers diagnostic solutions such as the cobas® eplex BCID-FP panel, which aids in the identification of bacterial and fungal organisms, including antibiotic resistance genes, in about 90 minutes of blood culture bottle positivity. This rapid identification supports timely treatment decisions, enhancing patient care and antimicrobial stewardship.
Mylan N.V., now part of Viatris, is a global pharmaceutical company headquartered in Canonsburg, Pennsylvania, USA. Established in 1961, Mylan has a significant presence in the fungal infections market. The company launched a generic version of Sporanox® (itraconazole) capsules, an antifungal medication used to treat various fungal infections, including those affecting the toenails and fingernails in non-immunocompromised patients.
Teva Pharmaceutical Industries Ltd., founded in 1935 and headquartered in Tel Aviv, Israel, is a leading global pharmaceutical company. Teva's portfolio includes a range of generic and specialty medicines. While the company has a strong focus on non-communicable diseases, including respiratory and cardiovascular conditions, it also offers treatments relevant to infectious diseases, which encompass fungal infections.
Sanofi S.A., established in 2004 and headquartered in Paris, France, is a global biopharmaceutical company. Sanofi's research and development efforts include a focus on infectious diseases, and the company has a collaboration program with the World Health Organization to combat neglected tropical diseases such as leishmaniasis and Chagas disease, which can involve fungal pathogens.
*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*
Other key players in the market include Pfizer Inc., GSK plc, Novartis AG, AstraZeneca plc, Johnson & Johnson Innovative Medicine, and Bristol Myers Squibb Company.
The market report offers a detailed analysis of the market based on the following segments:
Market Breakup by Types
Market Breakup by Drugs
Market Breakup by Dosage Forms
Market Breakup by Route of Administration
Market Breakup by End User
Market Breakup by Distribution Channel
Market Breakup by Region
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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| REPORT FEATURES | DETAILS |
| Base Year | 2025 |
| Historical Period | 2019-2025 |
| Forecast Period | 2026-2035 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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| Breakup by Types |
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| Breakup by Drugs |
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| Breakup by Dosage Forms |
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| Breakup by Route of Administration |
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| Breakup by End User |
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| Breakup by Distribution Channel |
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| Breakup by Region |
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| Market Dynamics |
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| Supplier Landscape |
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| Companies Covered |
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