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Report Overview

The Guillain-Barre syndrome treatment market was valued at USD 672.84 Million in 2025 and is expected to grow at a CAGR of 4.40%, reaching USD 1034.94 Million by 2035. The market growth is driven by rising incidence of autoimmune neurological disorders, advancements in immunotherapy, and increasing awareness among healthcare providers.

2025

Base Year

2019-2025

Historical Period

2026-2035

Forecast Period

  • The market growth is driven by the emphasis on developing new and effective treatment modalities that focus on specific molecular targets of Guillain-Barre syndrome pathology.

  • Joint ventures between academic and biotech companies aimed at integrating system-oriented programmes to offer targeted therapeutic strategies is amongst major market trends.

  • Increasing efforts to apply HEOR strategies for assessing the long-term effectiveness and value-based outcomes of the GBS therapeutic interventions is also expected to boost the market value in coming years.

Compound Annual Growth Rate

4.4%

Value in USD Million

2026-2035


*this image is indicative*

Guillain-Barre Syndrome Treatment Market Overview

Guillain-Barré Syndrome (GBS) is an autoimmune, polycentral, rare peripheral nerve disorder, which affects large nerves outside the brain and spinal cord. It can lead to muscle weakness and paralysis, amongst a range of other fatal complications. Usually, the initial signs include non-serious shocks and initial paralysis of legs, which later affects arms and upper body parts. Although the cause of this diseases unknown, GBS syndrome commonly develops after an individual has been exposed to a bacterial or viral infection. Possible options for treatment include the identification of entirely differentiated neurological techniques to manage some of the symptoms, minimize inflammation, and encourage axon regeneration.

Guillain-Barre Syndrome Treatment Market Growth Drivers

Increased cases of Guillain-Barré Syndrome Drive the Market in the Forecast Period

The rising prevalence of the condition is driving the demand for effective treatment alternatives. GBS syndrome is generally associated with proximal and distal muscle weakness especially of the limbs, with accompanying diminished or absent reflexes, sensorial changes, and rarely cranial neuropathies. This particularly, is a very fast developing disease because of nerve inflammation that results in paralyzed muscles and muscles weakness and often results to total paralysis in patients. While the specific factor has not yet been determined, GBS syndrome is mostly triggered by a digestive or respire infection. To prevent comorbidities and mortality rates associated with the condition, researchers and scientists are actively working on developing precise and efficient treatment.

Modernization of Medical Equipment Leading to Accurate Diagnosis

As the technology progresses, diagnosis of GBS syndrome has become comparatively accurate and much faster. For instance, neuroimaging technology enabled with refined protocols and specialized biomarkers have all made it easier for healthcare professionals to diagnose GBS syndrome. Prompt and accurate diagnosis is highly essential since it can assist in early treatment of the disease and avoid severe consequences. Such advancements in technology are therefore instrumental to provide better and efficient diagnostics for GBS syndrome and boost its treatment market as well.

Guillain-Barre Syndrome Treatment Market Trends

Recent Developments in the Guillain-Barre Syndrome Treatment Market

In October, 2023 Annexon Inc. achieved a significant milestone as the European Medicine Agency (EMA) granted orphan drug designation to ANX005 for treating Guillain-Barré Syndrome (GBS). ANX005, a humanized monoclonal antibody, targets C1q to stop complement-mediated inflammation and neuronal damage in GBS syndrome. The designation was based on a notable comparative efficacy analysis showing early muscle strength improvement compared to standard IVIg therapy, promising enhanced outcomes for GBS syndrome patients.

In March 2023, Hansa Biopharma completed enrollment in its phase 2 study of imlifidase in GBS syndrome. The phase II evaluated safety, tolerability, and efficacy in combination with standard (intravenous immunoglobulin) IVIg therapy. It was administered to patients before the standard of care.

Guillain-Barre Syndrome Treatment Market Segmentation

The Expert Market Research’s report titled “Guillain-Barre Syndrome Treatment Market Report and Forecast 2026-2035" offers a detailed analysis of the market based on the following segments:

Market Breakup by Type

  • Acute Inflammatory Demyelinating Polyradiculoneuropathy (AIDP)
  • Miller Fisher Syndrome (MFS)
  • Acute Motor Axonal Neuropathy (AMAN)

Market Breakup by Treatment

  • Intravenous Immunoglobulin
  • Plasma Exchange (Plasmapheresis)
  • Others

Market Breakup by Route of Administration

  • Parenteral
  • Oral
  • Others

Market Breakup by Gender

  • Male
  • Female

Market Breakup by Patient Type

  • Adult
  • Pediatric

Market Breakup by End User

  • Hospitals
  • Specialty Clinics
  • Others

Market Breakup by Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Others

Market Breakup by Region

  • United States
  • EU-4 and the United Kingdom
  • Japan
  • India

Guillain-Barre Syndrome Treatment Market Share

Intravenous Immunoglobulin is Anticipated to the Have Largest Market Share Based on Treatment

Based on the market segmentation by treatment, the market is divided into intravenous immunoglobulin, plasma exchange (plasmapheresis) and others. Intravenous immunoglobulin (IVIG) involves the application of an antibodies solution to manage the condition. The preference for this treatment can also be attributed to its faster absorption, leading to higher efficacy compared to other options. Wide availability of the IVIG products like Gamunex, Gammagard and Privigen also boosts the market share of this segment. Further, the rising research activities on IVIG are anticipated to contribute to the overall GBS syndrome treatment market growth.

Males Lead the Market Share Based on Gender

Based on gender, the segmentation includes males and females. The male to female incidence ratio is 1.5:1 for the condition. Hence, males are likely to lead the market share in the forecast period, owing to higher susceptibility of disease occurrence.

Guillain-Barre Syndrome Treatment Market by Region

Regionally, the market report offers insights on United States, EU-4 (Germany, France, Italy, and Spain), United Kingdom, Japan as well as India. The annual incidence in the United States population is around 1.2-3 per 100,000 individuals, out of which 8.6 cases per 100,000 occur at the age of 70-79 years. High prevalence rate, shift in the lifestyle and a rise in the per capita health expenditure are likely to impact the United States market share positively in the forecast period.

In United States and European countries, acute inflammatory demyelinating polyradiculoneuropathy (AIDP) has higher occurrence, while countries like Japan witnesses more cases of acute motor axonal neuropathy (AMAN). According to epidemiologic studies, Japan has a greater percentage of GBS syndrome cases in comparison to United States and European countries. With a robust medical research and development infrastructure, the region is expected to lead the market share for GBS syndrome treatment in the forecast period.

Leading Players in the Global Guillain-Barre Syndrome Treatment Market

The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding, and investment analysis, along with partnership and collaborations analysis by the leading players. The major companies in the market are as follows:

CSL Behring

Established in the year 2007 and headquartered in Pennsylvania, United States, this company has a special neuromuscular therapy line with intravenous immunoglobulins (IVIg) for GBS syndrome treatment.

OctaPharma AG

Founded in 1983 and headquartered in Lachen, Swutzerland. The company’s plasma-derived immunoglobulin therapy specialises in GBS syndrome which include immunological disorders.

Annexon Biosciences

This is an American biotechnology company that was established in the year 2011 with its headquarters located in California, United States. The company has a product pipeline under investigation for GBS syndrome.

*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*

Other market players include Cellenkos Inc., and Hansa Biopharma AB.

Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.

Key Questions Answered in the Guillain-Barre Syndrome Treatment Market

  • What was the global Guillain-Barre syndrome treatment market value in 2025?
  • What is the global Guillain-Barre syndrome treatment market forecast outlook for 2026-2035?
  • What are the regional markets covered in the EMR report?
  • What are the major factors aiding the global Guillain-Barre syndrome treatment market demand? 
  • What are the market's major drivers, opportunities, and restraints? 
  • Which regional market is expected to lead the market share in the forecast period? 
  • Which country is expected to experience expedited growth during the forecast period? 
  • What are the major global Guillain-Barre syndrome treatment market trends?
  • How does the rise in the geriatric population impact the market size?
  • Who are the key players involved in the Guillain-Barre syndrome treatment market?
  • What are the current unmet needs and challenges in the market?
  • How are partnerships, collaborations, mergers and acquisitions among the key market players shaping the market dynamics?
  • What is the market segmentation based on type?
  • What is the market breakup based on treatments?
  • What is the market segmentation based on route of administration?
  • What is the market breakup based on gender?
  • What are the major end users in the market?
  • What is the market breakup based on patient type?
  • What are the major distribution channels?
  • What factors influence the choice between intravenous immunoglobulin and plasma exchange as Guillain-Barre syndrome treatment options for patients?
  • How does the preference for parenteral administration versus oral administration vary across different regions for Guillain-Barre syndrome treatment market?

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Report Summary

Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

REPORT FEATURES DETAILS
Base Year 2025
Historical Period 2019-2025
Forecast Period 2026-2035
Scope of the Report

Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:

  • Type
  • Treatment
  • Route of Administration
  • Gender
  • Patient Type
  • End User
  • Distribution Channel
  • Region
Breakup by Type
  • Acute Inflammatory Demyelinating Polyradiculoneuropathy (AIDP)
  • Miller Fisher Syndrome (MFS)
  • Acute Motor Axonal Neuropathy (AMAN)
Breakup by Treatment
  • Intravenous Immunoglobulin
  • Plasma Exchange (Plasmapheresis)
  • Others
Breakup by Route of Administration
  • Parenteral
  • Oral
  • Others
Breakup by Gender
  • Male
  • Female 
Breakup by Patient Type
  • Adult
  • Pediatric
Breakup by End User
  • Hospitals
  • Specialty Clinics
  • Others
Breakup by Distribution Channel
  • Hospital Pharmacies
  • Retail Pharmacies
  • Others
Breakup by Region
  • United States
  • EU-4 and the United Kingdom
  • Japan
  • India 
Market Dynamics
  • Market Drivers and Constraints
  • SWOT Analysis
  • Porter’s Five Forces Model 
  • Key Demand Indicators
  • Key Price Indicators
  • Industry Events, Initiatives, and Trends 
  • Value Chain Analysis
Supplier Landscape
  • Market Structure
  • Company Profiles
    • Financial Analysis
    • Product Portfolio
    • Demographic Reach and Achievements
    • Mergers and Acquisitions
    • Certifications
Companies Covered
  • CSL Behring 
  • Cellenkos Inc.
  • Hansa Biopharma AB
  • OctaPharma AG
  • Annexon Bioscience

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