The global live cell encapsulation market size was valued at USD 258.2 million in 2023, driven by the increasing demand for innovative drug delivery systems across the globe. The market size is anticipated to grow at a CAGR of 3.65% during the forecast period of 2024-2032 to achieve a value of USD 356.5 million by 2032.
Cell encapsulation can graft rejection in tissue engineering applications. Cell microencapsulation technology involves immobilization of cells within a polymeric semi-permeable membrane. It enables the two-way diffusion of molecules, such as the inflow of molecules like oxygen, nutrients, and growth hormones, among others, that are necessary for cell metabolism and the outflow of molecules like waste products and proteins that are therapeutic.
Since the barrier is semi-permeable, immune cells and antibodies are prevented from attacking the encapsulated cells and viewing them as foreign intruders. After an organ transplant, cell encapsulation may lessen the requirement for long-term immunosuppressive medication use to manage side effects.
The market for live cell encapsulation has been witnessing significant growth owing to the innovative developments and strategic collaborations by the key players in the market. For example, BIO INX recently introduced Hydrobio INX N400, a pioneering bio-resin designed for live cell encapsulation using Nanoscribe's Two-Photon Polymerization technology. This biocompatible enables high-resolution bio-fabrication, along with facilitating the production of intricate biomimetic tissues by combining cell encapsulation with cell seeding. This launch exhibits the expansion of BIO INX and Nanoscribe's partnership, bringing 3D bio fabrication technology closer to the requirements of life sciences, biosciences, and biotechnology applications, further boosting the global live cell encapsulation market demand.
Additionally, the increasing mergers in the market are also directly contributing to the market growth. For example, Eli Lilly and Company's acquisition of Sigilon Therapeutics, a company specializing in functional cures for a variety of acute and chronic diseases, emphasizes the increasing interest in encapsulated cell therapies. Collaborative efforts between Lilly and Sigilon have already resulted in promising developments, such as SIG-002, aimed at alleviating the management burden for patients with type 1 diabetes by sensing blood glucose levels, restoring insulin production, and releasing it over the long term.
The increasing number of clinical studies to recognize the efficacy of cells is further contributing to the live cell encapsulation market growth. For example, clinical studies have highlighted the effectiveness of NK cells encapsulated in hydrogels created through 3D bioprinting for tumor immunotherapy. The intentional formation of micropores in these hydrogels enhances NK cell viability, lysis activity, and cytokine release.
Additionally, macropores, which can be generated through 3D bioprinting, ensure that NK cells receive essential elements for optimal functionality. These advancements demonstrate the growing potential of live cell encapsulation technologies in revolutionizing the field of medical treatments, offering new hope for patients with a variety of conditions, including cancer and diabetes, further propelling the market demand.
Market Breakup by Manufacturing Techniques
Market Breakup by Polymer Type
Market Breakup by Application
Market Breakup by Region
The growth of the market is driven by the increasing number of research studies examining chronic or acute organ damage caused by viruses, which has highlighted the importance of regenerative medicine. As a result, the demand to replace diseased or damaged tissues is increased, a need that often surpasses the available supply of tissue grafts. This scarcity has propelled the rapid expansion of regenerative medicine to meet the escalating demand. It is gaining significance for therapeutic purposes, further aiding the growth of live cell encapsulation market share. The market growth is further driven by the increasing demand for innovative drug delivery systems and the increased prevalence of target diseases.
North America is leading the global market due to the region being part of cutting-edge research studies in the field of drug discovery. This focus on innovation has led to higher adoption rates of live cell encapsulation products in the region. Additionally, the presence of key industry players and innovators has facilitated the development and dissemination of these technologies, further driving the live cell encapsulation market demand. The market is further driven by the surging demand for regenerative solutions and the pivotal role played by this technology in therapeutic advancements.
The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:
|Scope of the Report
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
|Breakup by Manufacturing Techniques
|Breakup by Polymer Type
|Breakup by Application
|Breakup by Region
*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage – Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Global Live Cell Encapsulation Market Overview
3.1 Global Live Cell Encapsulation Market Historical Value (2017-2023)
3.2 Global Live Cell Encapsulation Market Forecast Value (2024-2032)
4 Global Live Cell Encapsulation Market Landscape
4.1 Global Live Cell Encapsulation Developers Landscape
4.1.1 Analysis by Year of Establishment
4.1.2 Analysis by Company Size
4.1.3 Analysis by Region
4.2 Global Live Cell Encapsulation Product Landscape
4.2.1 Analysis by Manufacturing Techniques
4.2.2 Analysis by Polymer Type
4.2.3 Analysis by Application
5 Global Live Cell Encapsulation Market Dynamics
5.1 Market Drivers and Constraints
5.2 SWOT Analysis
5.3 Porter’s Five Forces Model
5.4 Key Demand Indicators
5.5 Key Price Indicators
5.6 Industry Events, Initiatives, and Trends
5.7 Value Chain Analysis
6 Global Live Cell Encapsulation Market Segmentation
6.1 Global Live Cell Encapsulation Market by Manufacturing Techniques
6.1.1 Market Overview
6.1.2 Simple Dripping
6.1.3 Electrostatic Dripping
6.1.4 Coaxial Airflow
6.1.5 Liquid-Jet Break-Up
6.1.6 Vibrating-Jet Technique
6.1.7 Jet Cutting
6.1.8 Rotating Disk Atomization
6.2 Global Live Cell Encapsulation Market by Polymer Type
6.2.1 Market Overview
6.2.3 HEMA-MMA (HydroxyethylMethacrylate-Methyl Methacrylate)
6.2.5 Siliceous Encapsulates
6.2.6 Cellulose Sulphate
6.2.7 PAN-PVC (Poly Acrylonitrile Vinyl Chloride)
6.3 Global Live Cell Encapsulation Market by Application
6.3.1 Market Overview
6.3.2 Drug Delivery
6.3.3 Regenerative Medicine
6.3.4 Cell Transplantation
6.4 Global Live Cell Encapsulation Market by Region
6.4.1 Market Overview
6.4.2 North America
6.4.4 Asia Pacific
6.4.5 Latin America
6.4.6 Middle East and Africa
7 North America Live Cell Encapsulation Market
7.1 Market Share by Country
7.2 United States of America
8 Europe Live Cell Encapsulation Market
8.1 Market Share by Country
8.2 United Kingdom
9 Asia Pacific Live Cell Encapsulation Market
9.1 Market Share by Country
10 Latin America Live Cell Encapsulation Market
10.1 Market Share by Country
11 Middle East and Africa Live Cell Encapsulation Market
11.1 Market Share by Country
11.2 Saudi Arabia
11.3 United Arab Emirates
11.5 South Africa
12 Patent Analysis
12.1 Analysis by Type of Patent
12.2 Analysis by Publication year
12.3 Analysis by Issuing Authority
12.4 Analysis by Patent Age
12.5 Analysis by CPC Analysis
12.6 Analysis by Patent Valuation
12.7 Analysis by Key Players
13 Grants Analysis
13.1 Analysis by year
13.2 Analysis by Amount Awarded
13.3 Analysis by Issuing Authority
13.4 Analysis by Grant Application
13.5 Analysis by Funding Institute
13.6 Analysis by NIH Departments
13.7 Analysis by Recipient Organization
14 Funding Analysis
14.1 Analysis by Funding Instances
14.2 Analysis by Type of Funding
14.3 Analysis by Funding Amount
14.4 Analysis by Leading Players
14.5 Analysis by Leading Investors
14.6 Analysis by Geography
15 Partnership and Collaborations Analysis
15.1 Analysis by Partnership Instances
15.2 Analysis by Type of Partnership
15.3 Analysis by Leading Players
15.4 Analysis by Geography
16 Regulatory Framework
16.1 Regulatory Overview
16.1.1 US FDA
16.1.2 EU EMA
16.1.3 INDIA CDSCO
16.1.4 JAPAN PMDA
17 Supplier Landscape
17.1 Merck KGaA
17.1.1 Financial Analysis
17.1.2 Product Portfolio
17.1.3 Demographic Reach and Achievements
17.1.4 Mergers and Acquisitions
17.2 ViaCyte, Inc.
17.2.1 Financial Analysis
17.2.2 Product Portfolio
17.2.3 Demographic Reach and Achievements
17.2.4 Mergers and Acquisitions
17.3 Living Cell Technologies Limited
17.3.1 Financial Analysis
17.3.2 Product Portfolio
17.3.3 Demographic Reach and Achievements
17.3.4 Mergers and Acquisitions
17.4 Balchem Inc.
17.4.1 Financial Analysis
17.4.2 Financial Portfolio
17.4.3 Demographic Reach and Achievements
17.4.4 Mergers and Acquisitions
17.5.1 Financial Analysis
17.5.2 Product Portfolio
17.5.3 Demographic Reach and Achievements
17.5.4 Mergers and Acquisitions
17.6 BÜCHI Labortechnik AG
17.6.1 Financial Analysis
17.6.2 Product Portfolio
17.6.3 Demographic Reach and Achievements
17.6.4 Mergers and Acquisitions
17.7 Sigilon Therapeutics, Inc.
17.7.1 Financial Analysis
17.7.2 Product Portfolio
17.7.3 Demographic Reach and Achievements
17.7.4 Mergers and Acquisitions
17.8 Encapsys, LLC.
17.8.1 Financial Analysis
17.8.2 Product Portfolio
17.8.3 Demographic Reach and Achievements
17.8.4 Mergers and Acquisitions
17.9 Evonik Industries AG
17.9.1 Financial Analysis
17.9.2 Product Portfolio
17.9.3 Demographic Reach and Achievements
17.9.4 Mergers and Acquisitions
17.10.1 Financial Analysis
17.10.2 Product Portfolio
17.10.3 Demographic Reach and Achievements
17.10.4 Mergers and Acquisitions
17.11 Neurotech Pharmaceuticals
17.11.1 Financial Analysis
17.11.2 Product Portfolio
17.11.3 Demographic Reach and Achievements
17.11.4 Mergers and Acquisitions
17.12 BioTime, Inc
17.12.1 Financial Analysis
17.12.2 Product Portfolio
17.12.3 Demographic Reach and Achievements
17.12.4 Mergers and Acquisitions
17.13 Gloriana Therapeutics
17.13.1 Financial Analysis
17.13.2 Product Portfolio
17.13.3 Demographic Reach and Achievements
17.13.4 Mergers and Acquisitions
18 Global Live Cell Encapsulation Market - Distribution Model (Additional Insight)
18.2 Potential Distributors
18.3 Key Parameters for Distribution Partner Assessment
19 Key Opinion Leaders (KOL) Insights (Additional Insight)
20 Company Competitiveness Analysis (Additional Insight)
20.1 Very Small Companies
20.2 Small Companies
20.3 Mid-Sized Companies
20.4 Large Companies
20.5 Very Large Companies
21 Payment Methods (Additional Insight)
21.1 Government Funded
21.2 Private Insurance
*Additional insights provided are customisable as per client requirements.
The market attained a value of about USD 258.2 million in 2023, driven by the increasing awareness.
The market is anticipated to grow at a CAGR of 3.65% during the forecast period of 2023-2031 and is likely to reach a market value of USD 356.5 million by 2032.
The increasing number of clinical studies and increasing mergers in the market are major trends influencing the market growth.
The major regions of the market include North America, Europe, Asia Pacific, Latin America, Middle East and Africa. North America is currently leading the global market.
Various polymers in the market are alginate, HEMA-MMA (HydroxyethylMethacrylate-Methyl Methacrylate), chitosan, siliceous encapsulates, cellulose sulphate, and PAN-PVC (Poly Acrylonitrile Vinyl Chloride), among others.
They find wide applications in drug delivery, regenerative medicine, cell transplantation, probiotics, and research.
Manufacturing techniques include simple dripping, electrostatic dripping, coaxial airflow, liquid-jet break-up, vibrating-jet technique, jet cutting, and rotating disk atomization.
Key players involved in the market are Merck KGaA, ViaCyte, Inc., Living Cell Technologies Limited, Balchem Inc., Lycored, BÜCHI Labortechnik AG, Sigilon Therapeutics, Inc., Encapsys, LLC., Evonik Industries AG, MIKROCAPS, Neurotech Pharmaceuticals, BioTime, Inc, and Gloriana Therapeutics.
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