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Global Oligonucleotide Synthesis Market: By Product: Oligonucleotides, Equipment/Synthesiser, Reagents, Services; By Application: PCR Primers, PCR Assays - Panels, Sequencing, Others; By End Use; Regional Analysis; Historical Market and Forecast (2016-2026); Market Dynamics; Competitive Landscape; Industry Events and Developments

Global Oligonucleotide Synthesis Market Outlook

The global oligonucleotide synthesis market reached a value of about USD 2.1 billion in 2020. The industry is further expected to grow at a CAGR of about 13.1% in the forecast period of 2021-2026 to reach a value of around USD 4.4 billion by 2026.

 

North America to be a Significant Regional Market for Oligonucleotide Synthesis

North America was a significant regional market for oligonucleotide synthesis and is expected to continue its prominent presence in the market in the coming years as well. The growing importance of life sciences research and development, attributed to this region's rising focus on improving the safety and quality of healthcare, the rising demand for high-quality research tools for data reproducibility, and the increasing focus on developing personalised therapeutics, has been catalysing the market for oligonucleotide synthesis.

 

Global Oligonucleotide Synthesis Market

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The Asia Pacific is also expected to witness a healthy growth within the oligonucleotide synthesis industry in the coming years. The increasing availability of synthesised oligonucleotides, the strong presence of pharma and biotech companies, and the growing research outsourcing to CROs are some of the major factors supporting the growth of the oligonucleotides synthesis industry in the Asia Pacific region. The existence of better healthcare infrastructure and the increasing usage of oligonucleotides by pharmaceutical companies of the region, and many strategic collaborations among the key players in the market are expected to further boost the growth of the oligonucleotide synthesis industry in the region. For instance, in 2020, IDT (United States) opened IDT China, an official business entity in China to better serve its customer base in the region, to reach out to new customers, and provide easier access to its complete portfolio of industry-leading products, including custom DNA and RNA oligos, probes, and primers.

 

Oligonucleotide Synthesis: Industry Definition and Segmentation

Synthetic oligonucleotides are single-stranded DNA fragments that have been chemically synthesised into short stretches. The technique is extremely useful in the laboratory because it provides rapid and inexpensive access to custom-made oligonucleotides of the desired sequence. It is also useful for carrying out the molecular diagnosis in several diseases, including detection of infectious diseases, such as hepatitis, SARS-COV2, and for the diagnosis of cancer.

By product, the market can be segmented into:

  • Oligonucleotides 
    • Breakup by type:
      • Column-Based Oligos
      • Array-Based Oligos
    • Breakup by Nucleic Acid Type
      • DNA Oligos
      • RNA Oligos
  • Equipment/Synthesiser  
  • Reagents  
  • Services 
    • Based on type:
      • Oligo Synthesis
    • Based on quantity:
      • 25 nmol
      • 50 nmol
      • 200 nmol
      • 1,000 nmol
      • 10,000 nmol
  • Purification
  • Modification

Based on application, the oligonucleotide synthesis industry is segmented into:

  • PCR Primers
  • PCR Assays-Panels
  • Sequencing
  • DNA Microarrays
  • Fluorescence in Situ Hybridisation (FISH) 
  • Antisense Oligonucleotides  
  • Others

On the basis of end use, the market is classified into:

  • Academic Research Institutes
  • Diagnostic Laboratories 
  • Pharmaceutical-Biotechnology Companies

The regional markets for oligonucleotide synthesis can be divided into North America, Europe, the Asia Pacific, Latin America, and the Middle East and Africa.

 

Rise in Research and Development Activity in Synthetic Oligonucleotide Boosting the Market Growth

The rise in research and development expenditure by the pharmaceutical and biotechnology companies to produce oligonucleotide products with increased therapeutic potential and fewer side effects is one of the factors that is fuelling the growth of the market. The rise in government support for synthetic biology and genome projects and robust research is expected to further drive the growth of the market. The development of new technologies has been aided greatly by government investments. Oligonucleotides are an important part of these technologies, and increased funding and development in these fields is expected to drive the market growth of oligonucleotide synthesis. These ongoing government-sponsored projects are anticipated to improve genomic technologies, particularly DNA sequencing, DNA amplification, next-generation sequencing (NGS), and gene expression.

Growing applications of synthesised oligonucleotides in molecular diagnostics and clinical applications and rise in demand for high-end customised oligos and upgradation in the purification of synthetic oligonucleotides is also boosting the growth of the oligonucleotide synthesis industry.  In recent years, this market has been witnessing a significant rise in the acquisition of various small-scale oligonucleotide synthesis companies by major key players to broaden their product and service offerings and expand their presence in the oligonucleotide synthesis industry, which is further aiding the market growth. Also, the advances in enzyme failure correction technology have reduced the occurrence of synthesis errors and are expected to aid the growth of the market in the coming years.

 

Key Industry Players in the Global Oligonucleotide Synthesis Market

The report gives a detailed analysis of the following key players in the global oligonucleotide synthesis market, covering their competitive landscape, capacity, and latest developments like mergers, acquisitions, and investments, expansions of capacity, and plant turnarounds:

  • Thermo Fisher Scientific Inc.
  • Eurofins Scientific SE
  • Merck KGaA 
  • Agilent Technologies, Inc.  
  • Bio-Synthesis Inc. 
  • LGC Biosearch Technologies 
  • Others 

The comprehensive EMR report provides an in-depth assessment of the industry based on the Porter's five forces model along with giving a SWOT analysis. 

 

REPORT FEATURES DETAILS
Base Year 2020
Historical Period 2016-2020
Forecast Period 2021-2026
Scope of the Report Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment- Product, Application, End Use, Region
Breakup by Product Oligonucleotides, Equipment/Synthesiser, Reagents, Services
Breakup by Application PCR Primers, PCR Assays - Panels, Sequencing, DNA Microarrays, Fluorescence In Situ Hybridisation (FISH), Antisense Oligonucleotides, Others
Breakup by End Use Academic Research Institutes, Diagnostic Laboratories, Pharmaceutical-Biotechnology Companies
Breakup by Region North America, Europe, Asia Pacific, Latin America, Middle East and Africa
Market Dynamics SWOT, Porter's Five Forces, EMR’s Key Indicators for Price and Demand
Competitive Landscape Market Structure, Company Profiles- Company Overview, Product Portfolio, Demographic Reach and Achievements, Certifications
Companies Covered Thermo Fisher Scientific Inc., Eurofins Scientific SE, Merck KGaA, Agilent Technologies, Inc., Bio-Synthesis Inc., LGC Biosearch Technologies, Others
Report Price and Purchase Option Explore our purchase options that are best suited to your resources and industry needs.
Delivery Format Delivered as an attached PDF and Excel through email, with an option of receiving an editable PPT, according to the purchase option.

 

*We at Expert Market Research always thrive to give you the latest information. The numbers in the article are only indicative and may be different from the actual report.

1    Preface
2    Report Coverage – Key Segmentation and Scope
3    Report Description

    3.1    Market Definition and Outlook
    3.2    Properties and Applications
    3.3    Market Analysis
    3.4    Key Players
4    Key Assumptions
5    Executive Summary

    5.1    Overview
    5.2    Key Drivers
    5.3    Key Developments
    5.4    Competitive Structure
    5.5    Key Industrial Trends
6    Snapshot
    6.1    Global
    6.2    Regional
7    Industry Opportunities and Challenges
8    Global Oligonucleotide Synthesis Market Analysis

    8.1    Key Industry Highlights
    8.2    Global Oligonucleotide Synthesis Historical Market (2016-2020) 
    8.3    Global Oligonucleotide Synthesis Market Forecast (2021-2026)
    8.4    Global Oligonucleotide Synthesis Market by Product
        8.4.1    Oligonucleotides 
            8.4.1.1    Market Share
            8.4.1.2    Historical Trend (2016-2020)
            8.4.1.3    Forecast Trend (2021-2026)
            8.4.1.4    Breakup by Type
                8.4.1.4.1    Column-Based Oligos
                    8.4.1.4.1.1    Market Share
                    8.4.1.4.1.2     Historical Trend (2016-2020)
                    8.4.1.4.1.3     Forecast Trend (2021-2026)
                8.4.1.4.2    Array-Based Oligos
                    8.4.1.4.2.1    Market Share
                    8.4.1.4.2.2     Historical Trend (2016-2020)
                    8.4.1.4.2.3     Forecast Trend (2021-2026)
            8.4.1.5    Breakup by Nucleic Acid Type
                8.4.1.5.1    DNA Oligos
                    8.4.1.5.1.1    Market Share
                    8.4.1.5.1.2     Historical Trend (2016-2020)
                    8.4.1.5.1.3     Forecast Trend (2021-2026)
                8.4.1.5.2    RNA Oligos
                    8.4.1.5.2.1    Market Share
                    8.4.1.5.2.2     Historical Trend (2016-2020)
                    8.4.1.5.2.3     Forecast Trend (2021-2026)
        8.4.2    Equipment/Synthesiser  
            8.4.2.1    Market Share
            8.4.2.2    Historical Trend (2016-2020)
            8.4.2.3    Forecast Trend (2021-2026)
        8.4.3    Reagents  
            8.4.3.1    Market Share
            8.4.3.2    Historical Trend (2016-2020)
            8.4.3.3    Forecast Trend (2021-2026)
        8.4.4    Services 
            8.4.4.1    Market Share
            8.4.4.2    Historical Trend (2016-2020)
            8.4.4.3    Forecast Trend (2021-2026)
            8.4.4.4    Based on Type
                8.4.4.4.1    Oligo Synthesis
                    8.4.4.4.1.1    Market Share
                    8.4.4.4.1.2     Historical Trend (2016-2020)
                    8.4.4.4.1.3     Forecast Trend (2021-2026)
                    8.4.4.4.1.4     Based on Quantity
                        8.4.4.4.1.4.1    25 nmol
                        8.4.4.4.1.4.2    50 nmol
                        8.4.4.4.1.4.3    200 nmol
                        8.4.4.4.1.4.4    1,000 nmol
                        8.4.4.4.1.4.5    10,000 nmol
                8.4.4.4.2    Purification
                    8.4.4.4.2.1    Market Share
                    8.4.4.4.2.2     Historical Trend (2016-2020)
                    8.4.4.4.2.3     Forecast Trend (2021-2026)
                8.4.4.4.3    Modification
                    8.4.4.4.3.1    Market Share
                    8.4.4.4.3.2     Historical Trend (2016-2020)
                    8.4.4.4.3.3     Forecast Trend (2021-2026)
    8.5    Global Oligonucleotide Synthesis Market by Application
        8.5.1    PCR Primers 
            8.5.1.1    Market Share
            8.5.1.2    Historical Trend (2016-2020)
            8.5.1.3    Forecast Trend (2021-2026)
        8.5.2    PCR Assays - Panels 
            8.5.2.1    Market Share
            8.5.2.2    Historical Trend (2016-2020)
            8.5.2.3    Forecast Trend (2021-2026)
        8.5.3    Sequencing
            8.5.3.1    Market Share
            8.5.3.2    Historical Trend (2016-2020)
            8.5.3.3    Forecast Trend (2021-2026)
        8.5.4    DNA Microarrays 
            8.5.4.1    Market Share
            8.5.4.2    Historical Trend (2016-2020)
            8.5.4.3    Forecast Trend (2021-2026)
        8.5.5    Fluorescence In Situ Hybridisation (FISH)
            8.5.5.1    Market Share
            8.5.5.2    Historical Trend (2016-2020)
            8.5.5.3    Forecast Trend (2021-2026)
        8.5.6    Antisense Oligonucleotides 
            8.5.6.1    Market Share
            8.5.6.2    Historical Trend (2016-2020)
            8.5.6.3    Forecast Trend (2021-2026)
        8.5.7    Others
    8.6    Global Oligonucleotide Synthesis Market by End Use
        8.6.1    Academic Research Institutes 
            8.6.1.1    Market Share
            8.6.1.2    Historical Trend (2016-2020)
            8.6.1.3    Forecast Trend (2021-2026)
        8.6.2    Diagnostic Laboratories
            8.6.2.1    Market Share
            8.6.2.2    Historical Trend (2016-2020)
            8.6.2.3    Forecast Trend (2021-2026)
        8.6.3    Pharmaceutical-Biotechnology Companies
            8.6.3.1    Market Share
            8.6.3.2    Historical Trend (2016-2020)
            8.6.3.3    Forecast Trend (2021-2026)
    8.7    Global Oligonucleotide Synthesis Market by Region
        8.7.1    Market Share
            8.7.1.1    North America
            8.7.1.2    Europe
            8.7.1.3    Asia Pacific
            8.7.1.4    Latin America
            8.7.1.5    Middle East and Africa
9    Regional Analysis
    9.1    North America
        9.1.1    Historical Trend (2016-2020)
        9.1.2    Forecast Trend (2021-2026)
        9.1.3    Breakup by Country
            9.1.3.1    United States of America 
            9.1.3.2    Canada
    9.2    Europe
        9.2.1    Historical Trend (2016-2020)
        9.2.2    Forecast Trend (2021-2026)
        9.2.3    Breakup by Country 
            9.2.3.1    United Kingdom
            9.2.3.2    Germany
            9.2.3.3    France
            9.2.3.4    Italy
            9.2.3.5    Others
    9.3    Asia Pacific
        9.3.1    Historical Trend (2016-2020)
        9.3.2    Forecast Trend (2021-2026)
        9.3.3    Breakup by Country
            9.3.3.1    China
            9.3.3.2    Japan
            9.3.3.3    India
            9.3.3.4    ASEAN
            9.3.3.5    Australia
            9.3.3.6    Others
    9.4    Latin America
        9.4.1    Historical Trend (2016-2020)
        9.4.2    Forecast Trend (2021-2026)
        9.4.3    Breakup by Country
            9.4.3.1    Brazil
            9.4.3.2    Argentina
            9.4.3.3    Mexico
            9.4.3.4    Others
    9.5    Middle East and Africa
        9.5.1    Historical Trend (2016-2020)
        9.5.2    Forecast Trend (2021-2026)
        9.5.3    Breakup by Country
            9.5.3.1    Saudi Arabia
            9.5.3.2    United Arab Emirates
            9.5.3.3    Nigeria
            9.5.3.4    South Africa
            9.5.3.5    Others
10    Market Dynamics
    10.1    SWOT Analysis
        10.1.1    Strengths
        10.1.2    Weaknesses
        10.1.3    Opportunities
        10.1.4    Threats
    10.2    Porter’s Five Forces Analysis
        10.2.1    Supplier’s Power
        10.2.2    Buyer’s Power
        10.2.3    Threat of New Entrants
        10.2.4    Degree of Rivalry
        10.2.5    Threat of Substitutes
    10.3    EMR’s Key Indicators for Demand
    10.4    EMR’s Key Indicators for Price
11    Value Chain Analysis
12    Competitive Landscape

    12.1    Market Structure
    12.2    Company Profiles
        12.2.1    Thermo Fisher Scientific Inc.
            12.2.1.1    Company Overview
            12.2.1.2    Product Portfolio
            12.2.1.3    Demographic Reach and Achievements
            12.2.1.4    Certifications
        12.2.2     Eurofins Scientific SE
            12.2.2.1    Company Overview
            12.2.2.2    Product Portfolio
            12.2.2.3    Demographic Reach and Achievements
            12.2.2.4    Certifications
        12.2.3    Merck KGaA
            12.2.3.1    Company Overview
            12.2.3.2    Product Portfolio
            12.2.3.3    Demographic Reach and Achievements
            12.2.3.4    Certifications
        12.2.4    Agilent Technologies, Inc. 
            12.2.4.1    Company Overview
            12.2.4.2    Product Portfolio
            12.2.4.3    Demographic Reach and Achievements
            12.2.4.4    Certifications
        12.2.5    Bio-Synthesis Inc.
            12.2.5.1    Company Overview
            12.2.5.2    Product Portfolio
            12.2.5.3    Demographic Reach and Achievements
            12.2.5.4    Certifications
        12.2.6    LGC Biosearch Technologies
            12.2.6.1    Company Overview
            12.2.6.2    Product Portfolio
            12.2.6.3    Demographic Reach and Achievements
            12.2.6.4    Certifications
        12.2.7    Others
13    Industry Events and Developments

 

List of Figures and Tables

1.    Global Oligonucleotide Synthesis Market: Key Industry Highlights, 2016 and 2026
2.    Global Oligonucleotide Synthesis Historical Market: Breakup by Product (USD Billion), 2016-2020
3.    Global Oligonucleotide Synthesis Market Forecast: Breakup by Product (USD Billion), 2021-2026
4.    Global Oligonucleotide Synthesis Historical Market: Breakup by Application (USD Billion), 2016-2020
5.    Global Oligonucleotide Synthesis Market Forecast: Breakup by Application (USD Billion), 2021-2026
6.    Global Oligonucleotide Synthesis Historical Market: Breakup by End Use (USD Billion), 2016-2020
7.    Global Oligonucleotide Synthesis Market Forecast: Breakup by End Use (USD Billion), 2021-2026
8.    Global Oligonucleotide Synthesis Historical Market: Breakup by Region (USD Billion), 2016-2020
9.    Global Oligonucleotide Synthesis Market Forecast: Breakup by Region (USD Billion), 2021-2026
10.    North America Oligonucleotide Synthesis Historical Market: Breakup by Country (USD Billion), 2016-2020
11.    North America Oligonucleotide Synthesis Market Forecast: Breakup by Country (USD Billion), 2021-2026
12.    Europe Oligonucleotide Synthesis Historical Market: Breakup by Country (USD Billion), 2016-2020
13.    Europe Oligonucleotide Synthesis Market Forecast: Breakup by Country (USD Billion), 2021-2026
14.    Asia Pacific Oligonucleotide Synthesis Historical Market: Breakup by Country (USD Billion), 2016-2020
15.    Asia Pacific Oligonucleotide Synthesis Market Forecast: Breakup by Country (USD Billion), 2021-2026
16.    Latin America Oligonucleotide Synthesis Historical Market: Breakup by Country (USD Billion), 2016-2020
17.    Latin America Oligonucleotide Synthesis Market Forecast: Breakup by Country (USD Billion), 2021-2026
18.    Middle East and Africa Oligonucleotide Synthesis Historical Market: Breakup by Country (USD Billion), 2016-2020
19.    Middle East and Africa Oligonucleotide Synthesis Market Forecast: Breakup by Country (USD Billion), 2021-2026
20.    Global Oligonucleotide Synthesis Market Structure

Key Questions Answered in the Report

In 2020, the global oligonucleotide synthesis market attained a value of nearly USD 2.1 billion.

The market is projected to grow at a CAGR of 13.1% between 2021 and 2026.

The market is estimated to witness a healthy growth in the forecast period of 2021-2026 to reach USD 4.4 billion by 2026.

The major drivers of the market include the development of new technologies, rise in demand for high end customised oligos, upgradation in the purification of synthetic oligonucleotides, acquisition of various small-scale oligonucleotide synthesis companies, and advances in enzyme failure correction technology.

Robust research and development activities and increases in investments and funding by the governments are the key industry trends propelling the growth of the market.

The major regions in the industry are North America, Latin America, the Middle East and Africa, Europe, and the Asia Pacific.

Oligonucleotides, equipment/synthesiser, reagents, and services are the significant products of oligonucleotide synthesis in the market.

The leading application segments in the industry are PCR primers, PCR assays-panels, sequencing, DNA microarrays, fluorescence in situ hybridisation (FISH), and antisense oligonucleotides, among others.

The major end use sectors of oligonucleotide synthesis in the market are academic research institutes, diagnostic laboratories, and pharmaceutical-biotechnology companies.

The major players in the industry are Thermo Fisher Scientific Inc., Eurofins Scientific SE, Merck KGaA, Agilent Technologies, Inc., Bio-Synthesis Inc., and LGC Biosearch Technologies, among others.

Analyst Review

The global oligonucleotide synthesis market attained a value of USD 2.1 billion in 2020, driven by the rising research and development expenditure. Aided by the investments and fundings by the government, the market is expected to witness a further growth in the forecast period of 2021-2026, growing at a CAGR of 13.1%. The market is projected to reach USD 4.4 billion by 2026.

EMR’s meticulous research methodology delves deep into the market, covering the macro and micro aspects of the industry. On the basis of product, the market is divided into oligonucleotides, equipment/synthesiser, reagents, and services. Based on application, the oligonucleotide synthesis industry can be segmented into PCR primers, PCR assays-panels, sequencing, DNA microarrays, fluorescence in situ hybridisation (FISH), and antisense oligonucleotides, among others. On the basis of end use, the market is classified into academic research institutes, diagnostic laboratories, and pharmaceutical-biotechnology companies. The major regional markets for oligonucleotide synthesis are North America, Europe, the Asia Pacific, Latin America, and the Middle East and Africa. The key players in the above market include Thermo Fisher Scientific Inc., Eurofins Scientific SE, Merck KGaA, Agilent Technologies, Inc., Bio-Synthesis Inc., and LGC Biosearch Technologies, among others.

EMR’s research methodology uses a combination of cutting-edge analytical tools and the expertise of their highly accomplished team, thus, providing their customers with market insights that are accurate, actionable, and help them remain ahead of their competition.

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