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The global transplantation market size reached a value of USD 13.8 billion in 2022. The market is likely to grow at a rate of 9.4% in the forecast period of 2023-2031 to reach a market value of USD 31.5 billion by 2031. The increasing research and developmental activities, along with technological advancements are supporting the market growth.
Transplantation is one of the most advanced and great advances in modern medicine. Transplantation is a procedure of removing organ, tissue, or cells from one subject and surgically placing it in another subject whose organ has failed. The former is called the donor, while the latter is referred to as a recipient. Transplantation is generally considered the last therapeutic intervention in cases of organ failure or damage due to any disease or injury.
The organs that can be donated include the heart, kidneys, pancreas, uterus, liver, lungs, and intestine. The tissues being transplanted from the healthy donor to the recipient are the bones, heart valves, skin patches, tendons, cornea, and nerves. Out of the tissues, cornea and musculoskeletal grafts are majorly transplanted, while kidneys are the most transplanted organs in the human body.
There are several types of transplants, including autograft, allograft, domino transplants, xenograft, and ABO-incompatible transplants. The organs or tissues can be donated from either a living or deceased donor. There has been the formulation of several laws and regulations in both developed and developing countries for enhancing the safety and availability of organ or tissue transplants to their citizens.
The transplantation market can be categorised into the following segments:
Market Breakup by Product
Market Breakup by Type of Transplant
Transplantation Market Breakup by Application
Market Breakup by End User
Market Breakup by Region
The growth of the transplantation market is driven by the rising cases of organ failure, which can be attributed to the growing incidence of acute and chronic diseases, including poisoning, trauma, leukaemia, and sepsis. This has led to increased demand for tissue and organ transplants and thus will facilitate market growth and development.
The emergence of unhealthy eating habits, increased consumption of alcohol, drug abuse and lack of physical exercise are also increasing the chances of organ failure. This is anticipated to accelerate the demand for organ or tissue transplants and will directly influence the growth of the transplantation market during the forecast period.
Tissue products are expected to hold a significant share in the market owing to the increasing number of transplantation procedures incorporating the application of tissue products, such as orthopaedic soft tissues, heart valves, and bone marrow. This is expected to attribute to the major share of this segment. The growing number of product launches and approvals and the rising number of mergers and acquisitions are also projected to fuel the market development.
North America is anticipated to dominate the transplantation market due to the well-developed healthcare facilities and the strategic presence of major pharmaceutical companies, like Arthrex, Zimmer Biomet, Stryker, Novartis, and Medtronic in the region. Further, the increasing initiatives by the government and other non-governmental organisations to aware people of organ donations are also expected to accelerate the market in the forthcoming years.
Transplantation is a wide branch of modern medicine and is used for the treatment of several therapeutic indications. Tremendous efforts of scientists, researchers, and healthcare professionals have led to innovative transplantation methods that have helped to improve healthcare and the global economy.
One of the emerging therapies incorporating transplantation is cell transplantation or cell therapy. The therapeutic interventions include hematopoietic stem cell transplantation, neural stem cell therapy, and mesenchymal stem cell therapy. These therapies are utilized in the cases of myeloid malignancies, osteogenesis imperfecta, Hurler’s syndrome, and other haematological indications.
The transplantation of the entire bladder or the bladder tissue from a healthy donor to the recipient has also provided therapeutic effects in the management of renal disorders. The bladders are biosynthesized which can be then transplanted into the patient’s body. Kidney and liver transplants are being utilized in case of renal dysfunction and hepatic failure.
A heart transplant is used in patients suffering from congestive heart failure, for restoring the normal functioning of the heart. Other organ transplants including lung transplants are also used in the treatment of pulmonary disorders, wherein, one or both lungs have stopped functioning and the patient is expected to survive for less than two years.
Stem cell transplant is another transplantation technique which is applied for the management of the disease damaging the bone marrow cells. This type of transplant gives rise to novel blood cells, thus replacing the damaged cells in the body.
With extensive research and innovations, clinical researchers are working on discovering novel organ/tissue transplantations that would be useful in the treatment of novel therapeutic indications. The undergoing clinical trials are expected to utilize novel technologies and methods, that are more efficient therapeutically.
In the United States, LyGenesis, a key market player is performing clinical trials for the novel technique, involves the development of ectopic livers. In this intervention, the cells are injected from the donor liver which is expected to form multiple mini livers thus, expected to keep the patient healthy. If successfully passed, this can be used for the management of patients suffering from end-stage liver disease.
A novel method of islet transplantation is under stage III clinical trials for testing the degree and effect of insulin independence in patients suffering from diabetes. In this method, the normal islet cells from the healthy donor are injected into the patient, which aids in the production of insulin and thus controls diabetes.
Paragonix technologies, a major market leader, has launched a novel organ tracking technology to make the entire in-transit of donor organs transparent. This will be used to capture the exact location of the device and thus, will help in early transportation and will increase the chances of saving the patient life.
The positive results of these trials, the invention of novel methods, better advancements and increased understanding and awareness will also propel the market expansion in the near future.
The report gives an in-depth analysis of the key players involved in the market, sponsors manufacturing the drugs, and putting them through trials to get FDA approvals. The transplantation market companies included in the market are as follows:
REPORT FEATURES | DETAILS |
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Base Year | 2022 |
Historical Period | 2016-2022 |
Forecast Period | 2023-2031 |
Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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Breakup by Category of Product |
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Breakup by Type of Transplant |
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Breakup by Application |
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Breakup by End-User |
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Breakup by Region |
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Market Dynamics |
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Supplier Landscape |
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Companies Covered |
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*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.
1 Preface
1.1 Objectives of the Study
1.1.1 Research Objectives
1.1.2 Key Findings of the Report
1.2 Limitations of the Study and Scope for Future Research
2 Research Methodology
3 Executive Summary
4 Global Transplantation Overview
4.1 Guidelines and Stages
4.2 Pathophysiology
4.3 Screening and Diagnosis
4.4 Treatment Pathway
5 Patient Profile
5.1 Patient Profile Overview
5.2 Patient Psychology and Emotional Impact Factors
5.3 Risk Assessment and Treatment Success Rate
6 Global Transplantation Market
6.1 Global Transplantation Market Overview
6.2 Global Transplantation Market Analysis
6.2.1 Market Overview
6.2.1.1 Global Transplantation Market Historical Value (2016-2022)
6.2.1.2 Global Transplantation Market Forecast Value (2023-2031)
6.2.2 Global Transplantation Market by Category of Product
6.2.2.1 Market Overview
6.2.2.1.1 Transplant Preservative Solutions
6.2.2.1.2 Transplant Diagnostics
6.2.2.1.3 Tissue Products
6.2.2.1.4 Immunosuppressive Drugs
6.2.2.1.5 Others
6.2.3 Global Transplantation Market by Type of Transplant
6.2.3.1 Market Overview
6.2.3.1.1 Solid Organ Transplant
6.2.3.1.1.1 Kidney
6.2.3.1.1.2 Heart
6.2.3.1.1.3 Lungs
6.2.3.1.1.4 Liver
6.2.3.1.1.5 Intestine
6.2.3.1.1.6 Others
6.2.3.1.2 Stem Cell Transplant
6.2.3.1.2.1 Autologous Transplants
6.2.3.1.2.2 Allogenic Transplants
6.2.3.1.3 Tissue Transplant
6.2.3.1.3.1 Autografts
6.2.3.1.3.2 Allografts
6.2.3.1.4 Others
6.2.4 Global Transplantation Market by Application
6.2.4.1 Market Overview
6.2.4.1.1 Clinical Therapeutics
6.2.4.1.2 Translational Research
6.2.4.1.3 Diagnostic Purposes
6.2.4.1.4 Others
6.2.5 Global Transplantation Market by End-User
6.2.5.1 Market Overview
6.2.5.1.1 Hospitals
6.2.5.1.2 Transplantation Centres
6.2.5.1.3 Others
6.2.6 Global Transplantation Market by Region
6.2.6.1 Market Overview
6.2.6.1.1 North America
6.2.6.1.1.1 Historical Trend (2016-2022)
6.2.6.1.1.2 Forecast Trend (2023-2031)
6.2.6.1.2 Europe
6.2.6.1.2.1 Historical Trend (2016-2022)
6.2.6.1.2.2 Forecast Trend (2023-2031)
6.2.6.1.3 Asia Pacific
6.2.6.1.3.1 Historical Trend (2016-2022)
6.2.6.1.3.2 Forecast Trend (2023-2031)
6.2.6.1.4 Latin America
6.2.6.1.4.1 Historical Trend (2016-2022)
6.2.6.1.4.2 Forecast Trend (2023-2031)
6.2.6.1.5 Middle East and Africa
6.2.6.1.5.1 Historical Trend (2016-2022)
6.2.6.1.5.2 Forecast Trend (2023-2031)
7 North America Transplantation Market
7.1 United States of America
7.1.1 Historical Trend (2016-2022)
7.1.2 Forecast Trend (2023-2031)
7.2 Canada
7.2.1 Historical Trend (2016-2022)
7.2.2 Forecast Trend (2023-2031)
8 Europe Transplantation Market
8.1 United Kingdom
8.1.1 Historical Trend (2016-2022)
8.1.2 Forecast Trend (2023-2031)
8.2 Germany
8.2.1 Historical Trend (2016-2022)
8.2.2 Forecast Trend (2023-2031)
8.3 France
8.3.1 Historical Trend (2016-2022)
8.3.2 Forecast Trend (2023-2031)
8.4 Italy
8.4.1 Historical Trend (2016-2022)
8.4.2 Forecast Trend (2023-2031)
9 Asia Pacific Transplantation Market
9.1 China
9.1.1 Historical Trend (2016-2022)
9.1.2 Forecast Trend (2023-2031)
9.2 Japan
9.2.1 Historical Trend (2016-2022)
9.2.2 Forecast Trend (2023-2031)
9.3 India
9.3.1 Historical Trend (2016-2022)
9.3.2 Forecast Trend (2023-2031)
9.4 ASEAN
9.4.1 Historical Trend (2016-2022)
9.4.2 Forecast Trend (2023-2031)
9.5 Australia
9.5.1 Historical Trend (2016-2022)
9.5.2 Forecast Trend (2023-2031)
10 Latin America Transplantation Market
10.1 Brazil
10.1.1 Historical Trend (2016-2022)
10.1.2 Forecast Trend (2023-2031)
10.2 Argentina
10.2.1 Historical Trend (2016-2022)
10.2.2 Forecast Trend (2023-2031)
10.3 Mexico
10.3.1 Historical Trend (2016-2022)
10.3.2 Forecast Trend (2023-2031)
11 Middle East and Africa Transplantation Market
11.1 Saudi Arabia
11.1.1 Historical Trend (2016-2022)
11.1.2 Forecast Trend (2023-2031)
11.2 United Arab Emirates
11.2.1 Historical Trend (2016-2022)
11.2.2 Forecast Trend (2023-2031)
11.3 Nigeria
11.3.1 Historical Trend (2016-2022)
11.3.2 Forecast Trend (2023-2031)
11.4 South Africa
11.4.1 Historical Trend (2016-2022)
11.4.2 Forecast Trend (2023-2031)
12 Current Scenario Evaluation and Regulatory Framework
12.1 Emerging Therapies and Clinical Trials
12.2 Patent Landscape
12.2.1 Patent Overview
12.2.1.1 Patent Status and Expiry
12.2.1.2 Timelines from Drug Development to Commercial Launch
12.2.1.3 New Drug Application
12.2.1.3.1 Documentation and Approval Process
12.3 Cost of Treatment
12.4 Regulatory Framework
12.4.1 Regulatory Overview
12.4.1.1 US FDA
12.4.1.2 EU EMA
12.4.1.3 INDIA CDSCO
12.4.1.4 JAPAN PMDA
12.4.1.5 Others
13 Challenges & Unmet Needs
13.1 Treatment Pathway Challenges
13.2 Compliance and Drop-Out Analysis
13.3 Awareness and Prevention Gaps
14 Global Transplantation Market Dynamics
14.1 Market Drivers and Constraints
14.2 SWOT Analysis
14.3 Porter’s Five Forces Model
14.4 Key Demand Indicators
14.5 Key Price Indicators
14.6 Industry Events, Initiatives & Trends
14.7 Value Chain Analysis
15 Supplier Landscape
15.1 AbbVie Inc.
15.1.1 Company Overview
15.1.2 Product Portfolio
15.1.3 Demographic Reach and Achievements
15.1.4 Mergers and Acquisitions
15.1.5 Certifications
15.2 Arthrex, Inc.
15.2.1 Company Overview
15.2.2 Product Portfolio
15.2.3 Demographic Reach and Achievements
15.2.4 Mergers and Acquisitions
15.2.5 Certifications
15.3 Zimmer Biomet
15.3.1 Company Overview
15.3.2 Product Portfolio
15.3.3 Demographic Reach and Achievements
15.3.4 Mergers and Acquisitions
15.3.5 Certifications
15.4 Medtronic
15.4.1 Company Overview
15.4.2 Product Portfolio
15.4.3 Demographic Reach and Achievements
15.4.4 Mergers and Acquisitions
15.4.5 Certifications
15.5 Novartis AG
15.5.1 Company Overview
15.5.2 Product Portfolio
15.5.3 Demographic Reach and Achievements
15.5.4 Mergers and Acquisitions
15.5.5 Certifications
15.6 Stryker
15.6.1 Company Overview
15.6.2 Product Portfolio
15.6.3 Demographic Reach and Achievements
15.6.4 Mergers and Acquisitions
15.6.5 Certifications
15.7 21st Century Medicine
15.7.1 Company Overview
15.7.2 Product Portfolio
15.7.3 Demographic Reach and Achievements
15.7.4 Mergers and Acquisitions
15.7.5 Certifications
15.8 BioLife Solutions
15.8.1 Company Overview
15.8.2 Product Portfolio
15.8.3 Demographic Reach and Achievements
15.8.4 Mergers and Acquisitions
15.8.5 Certifications
15.9 Teva Pharmaceutical Industries Ltd.
15.9.1 Company Overview
15.9.2 Product Portfolio
15.9.3 Demographic Reach and Achievements
15.9.4 Mergers and Acquisitions
15.9.5 Certifications
15.10 Astellas Pharma Inc.
15.10.1 Company Overview
15.10.2 Product Portfolio
15.10.3 Demographic Reach and Achievements
15.10.4 Mergers and Acquisitions
15.10.5 Certifications
16 Recommendations and Discussion
17 Global Transplantation Distribution Model (Additional Insight)
17.1 Overview
17.2 Potential Distributors
17.3 Key Parameters for Distribution Partner Assessment
18 Payment Methods (Additional Insight)
18.1 Government Funded
18.2 Private Insurance
18.3 Out-of-Pocket
*Additional insights provided are customizable as per client requirements.
The market size is likely to reach a value of USD 13.8 billion in 2022.
The market is likely to grow at a CAGR of 9.4% during the forecast period of 2023-2031 to attain a value of USD 31.5 billion by 2031.
Based on the product, the market is segmented into transplant preservative solutions, transplant diagnostics, tissue products, and immunosuppressive drugs, among others.
Based on the transplant type, the market is categorised into solid organ transplant, tissue transplant, and stem cell transplant.
Based on the application, the market is segmented into clinical therapeutics, translational research, and diagnostic purposes, among others.
Based on the end user, the market is categorised into hospitals and transplantation centres, among others.
The different regions in the market are North America, Europe, Asia Pacific, Latin America, the Middle East and Africa.
The key companies in the market are AbbVie Inc., Arthrex, Inc., Zimmer Biomet, Medtronic, Novartis AG, Stryker, 21st Century Medicine, BioLife Solutions, Teva Pharmaceutical Industries Ltd., and Astellas Pharma Inc., among others.
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