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Global Ankylosing Spondylitis Treatment Market Share, Size, Growth: By Drug Type: Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), TNF Inhibitors, Others; By Indication Type: Reactive Arthritis, Psoriatic Arthritis, IBD Associated Arthritis, Others; By Treatment Method; By Treatment Channel; Regional Analysis; Supplier Landscape; 2023-2031
Global Ankylosing Spondylitis Treatment Market Outlook
The global ankylosing spondylitis treatment market size attained a value of USD 4.64 billion in 2022. The market is expected to grow further at a CAGR of 8.1% during the forecast period of 2023-2031 to attain a value of USD 9.37 billion by 2031, driven by the rising prevalence of the condition due to inactive lifestyle of people.
Ankylosing Spondylitis Treatment Market: Introduction
Ankylosing spondylitis or axial spondylarthritis is a type of chronic arthritis that severely affects the spine, lower back, and the hips and leads to inflammation in these parts. Ankylosing spondylitis causes severe inflammation in the sacroiliac joints, which are located amidst the spinal and pelvis base. It is a disease which can trigger the bones in the vertebrae to fuse, over a period of time. The condition often starts after the age of 20 due to factors like inactive lifestyle, bad posture, as well as genetic factors. People suffering from diseases like Crohn’s disease, Psoriasis, or Ulcerative colitis are also at a high risk of getting ankylosing spondylitis.
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Inflammation or sacroiliitis is among the primary symptoms of this condition, and it often spreads further to other parts of the body like the spinal cord, which is made up of vertebrae and other bones, and even eyes. This inflammation can even result in the formation of additional calcium around the bone, which can eventually form up as a new bone and further complicate the problem.
The symptoms of the condition can vary from person to person. While some may experience sharp pain, some might not have any symptoms at all. The most common symptoms of the condition include severe pain (continuous or in intervals) in different parts like the joint between the spinal base and the pelvis, vertebrae, lower back, places where tendons and ligaments attach to bones, and it can even go down to the back of the heel. Other parts that are often affected due to the condition include the cartilage, hip and shoulder joints, among others.
Ankylosing spondylitis can be of two types-
- Ankylosing Spondylitis/ Axial Spondylarthritis- When the condition can be detected through X-ray.
- Nonradiographic Axial Spondyloarthritis- When the condition needs more tests like imaging tests and blood tests.
Ankylosing spondylitis does not have any cure as such but the progression of the condition can be restricted to a significant extent with regular treatment and changes in lifestyles and posture. While the condition does not pose any direct threat to life, it might lead to certain complications if not treated timely. These potential complications include stiffness or inflexibility of the spine, inflammation in the eyes, compression fractures, and even heart problems.
Ankylosing Spondylitis Treatment Market Segmentations
The market can be categorised into drug type, indication type, treatment methods, treatment channel, and major regions.
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Market Breakup by Drug Type
- Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
- TNF Inhibitors
- Others
Market Breakup by Indication Type
- Reactive Arthritis
- Psoriatic Arthritis
- IBD Associated Arthritis
- Juvenile Spondyloarthropathy
- Undifferentiated Spondyloarthropathy
- Others
Market Breakup by Treatment Method
- Physiotherapy and Exercise
- Painkillers
- Biological Treatments
- Corticosteroids
- Disease Modifying Anti Rheumatic Drugs (DMARDs)
- Surgery
- Others
Market by Treatment Channel
- Public
- Private
Market Breakup by Region
- North America
- United States of America
- Canada
- Europe
- United Kingdom
- Germany
- France
- Italy
- Others
- Asia Pacific
- China
- Japan
- India
- ASEAN
- Australia
- Others
- Latin America
- Brazil
- Argentina
- Mexico
- Others
- Middle East and Africa
- Saudi Arabia
- United Arab Emirates
- Nigeria
- South Africa
- Others
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Ankylosing Spondylitis Treatment Market- Epidemiology
The condition can start affecting people right from the age of 20 and continue troubling them thereafter if not treated timely. Based on gender, men are more likely to be in this condition than women and the symptoms also differ between men and women. Based on race, the condition is more likely to affect Americans than Africans.
Ankylosing Spondylitis Treatment Market- Therapeutic Landscape
Ankylosing spondylitis is a lifelong condition and does not have any permanent cure. While there are no cures available for the condition, there are various treatment options available in the market. Along with these treatments, the patient can also practise exercises to limit further progression of the condition. Some of these treatments are:
- Exercise: Exercise is the first and the foremost advice given by the doctors. These exercises would help the patient reduce the pain as well as improve the posture or at least restrict any further damage to the spine. The condition is caused by inactivity and adopting an active lifestyle can prove to be beneficial.
- NSAIDs or Nonsteroidal Anti-Inflammatory Drugs: Some of the most common NSAIDs include drugs like ibuprofen (Advil®) and naproxen (Aleve®), among others. These drugs can provide immediate but term relief from pain and inflammation.
- DMARDs or Disease Modifying Anti-Rheumatic Drugs: Sulfasalazine is the most common DMARDs in the market. It can help reduce the inflammation, swelling, and pain in the joints. The new DMARDs called biologics, like TNF or tumour necrosis factor and IL-17 or interleukin inhibitors, can alter the immune system to manage inflammation.
- Corticosteroids: These are available in the form of injections and can release the pain and inflammation.
- Surgery: It is mostly the last resort for the patients when nothing else helps. With this surgery, an artificial joint is implanted to correct the curved spine.
- Physiotherapy: A physiotherapist can significantly help the patient manage the inflammation and swelling and can also recommend a set of customised exercises. They can also recommend and help with aquatic or hydrotherapy which can help ease the spinal cord.
Key Players in the Global Ankylosing Spondylitis Treatment Market
The major companies working on the drugs and treatment of the condition and investing in the clinical trials include the following:
- Abvie, Inc.
- Amgen Inc.
- Eli Lilly & Company
- Gilead Sciences
- Johnson & Johnson (Janssen)
- Pfizer Inc.
- Novartis AG
Key Highlights of the Report
| REPORT FEATURES | DETAILS |
|---|---|
| Base Year | 2022 |
| Historical Period | 2016-2022 |
| Forecast Period | 2023-2031 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
|
| Breakup by Drug Type |
|
| Breakup by Indication Type |
|
| Breakup by Treatment Method |
|
| Breakup by Treatment Channel |
|
| Breakup by Region |
|
| Market Dynamics |
|
| Competitive Landscape |
|
| Companies Covered |
|
*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.
1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage – Key Segmentation and Scope
2 Research Methodology
3 Executive Summary
4 Ankylosing Spondylitis (AS) Overview
4.1 Guidelines and Stages
4.2 Pathophysiology
4.3 Screening and Diagnosis
4.4 Treatment Pathway
5 Patient Profile
5.1 Patient Profile Overview
5.2 Patient Psychology and Emotional Impact Factors
5.3 Risk Assessment and Treatment Success Rate
6 Current Scenario Evaluation and Regulatory Framework
6.1 Emerging Therapies and Clinical Trials
6.2 Patent Landscape
6.2.1 Patent Overview
6.2.1.1 Patent Status and Expiry
6.2.1.2 Timelines from Drug Development to Commercial Launch
6.2.1.3 New Drug Application
6.2.1.3.1 Documentation and Approval Process
6.2.2 Cost of Treatment
6.2.3 Regulatory Framework
6.2.3.1 Regulatory Overview
6.2.3.1.1 US FDA
6.2.3.1.2 EU EMA
6.2.3.1.3 INDIA CDSCO
6.2.3.1.4 JAPAN PMDA
6.2.3.1.5 Others
7 Challenges and Unmet Needs
7.1 Treatment Pathway Challenges
7.2 Compliance and Drop-Out Analysis
7.3 Awareness and Prevention Gaps
8 Global Ankylosing Spondylitis Treatment Market
8.1 Global Ankylosing Spondylitis Treatment Market Overview
8.2 Global Ankylosing Spondylitis Treatment Market Analysis
8.2.1 Market Overview
8.2.1.1 Global Ankylosing Spondylitis Treatment Market Historical Value (2016-2022)
8.2.1.2 Global Ankylosing Spondylitis Treatment Market Forecast Value (2023-2031)
8.3 Global Ankylosing Spondylitis Treatment Market by Drug Type
8.3.1 Market Overview
8.3.1.1 Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
8.3.1.2 TNF Inhibitors
8.3.1.3 Others
8.4 Global Ankylosing Spondylitis Treatment Market by Indication Type
8.4.1 Market Overview
8.4.1.1 Reactive Arthritis
8.4.1.2 Psoriatic Arthritis
8.4.1.3 IBD Associated Arthritis
8.4.1.4 Juvenile Spondyloarthropathy
8.4.1.5 Undifferentiated Spondyloarthropathy
8.4.1.6 Others
8.5 Global Ankylosing Spondylitis Treatment Market by Treatment Method
8.5.1 Market Overview
8.5.1.1 Physiotherapy and Exercise
8.5.1.2 Painkillers
8.5.1.3 Biological Treatments
8.5.1.4 Corticosteroids
8.5.1.5 Disease Modifying Anti Rheumatic Drugs (DMARDs)
8.5.1.6 Surgery
8.5.1.7 Others
8.6 Global Ankylosing Spondylitis Treatment Market by Treatment Channel
8.6.1 Market Overview
8.6.1.1 Public
8.6.1.2 Private
8.7 Global Ankylosing Spondylitis Treatment Market by Region
8.7.1 Market Overview
8.7.1.1 North America
8.7.1.2 Europe
8.7.1.3 Asia Pacific
8.7.1.4 Latin America
8.7.1.5 Middle East and Africa
9 North America Ankylosing Spondylitis Treatment Market
9.1 Market Share by Country
9.2 United States of America
9.2.1 Historical Trend (2016-2022)
9.2.2 Forecast Trend (2023-2031)
9.3 Canada
9.3.1 Historical Trend (2016-2022)
9.3.2 Forecast Trend (2023-2031)
10 Europe Ankylosing Spondylitis Treatment Market
10.1 Market Share by Country
10.2 United Kingdom
10.2.1 Historical Trend (2016-2022)
10.2.2 Forecast Trend (2023-2031)
10.3 Germany
10.3.1 Historical Trend (2016-2022)
10.3.2 Forecast Trend (2023-2031)
10.4 France
10.4.1 Historical Trend (2016-2022)
10.4.2 Forecast Trend (2023-2031)
10.5 Italy
10.5.1 Historical Trend (2016-2022)
10.5.2 Forecast Trend (2023-2031)
10.6 Others
11 Asia Pacific Ankylosing Spondylitis Treatment Market
11.1 Market Share by Country
11.2 China
11.2.1 Historical Trend (2016-2022)
11.2.2 Forecast Trend (2023-2031)
11.3 Japan
11.3.1 Historical Trend (2016-2022)
11.3.2 Forecast Trend (2023-2031)
11.4 India
11.4.1 Historical Trend (2016-2022)
11.4.2 Forecast Trend (2023-2031)
11.5 ASEAN
11.5.1 Historical Trend (2016-2022)
11.5.2 Forecast Trend (2023-2031)
11.6 Australia
11.6.1 Historical Trend (2016-2022)
11.6.2 Forecast Trend (2023-2031)
11.7 Others
12 Latin America Ankylosing Spondylitis Treatment Market
12.1 Market Share by Country
12.2 Brazil
12.2.1 Historical Trend (2016-2022)
12.2.2 Forecast Trend (2023-2031)
12.3 Argentina
12.3.1 Historical Trend (2016-2022)
12.3.2 Forecast Trend (2023-2031)
12.4 Mexico
12.4.1 Historical Trend (2016-2022)
12.4.2 Forecast Trend (2023-2031)
12.5 Others
13 Middle East and Africa Ankylosing Spondylitis Treatment Market
13.1 Market Share by Country
13.2 Saudi Arabia
13.2.1 Historical Trend (2016-2022)
13.2.2 Forecast Trend (2023-2031)
13.3 United Arab Emirates
13.3.1 Historical Trend (2016-2022)
13.3.2 Forecast Trend (2023-2031)
13.4 Nigeria
13.4.1 Historical Trend (2016-2022)
13.4.2 Forecast Trend (2023-2031)
13.5 South Africa
13.5.1 Historical Trend (2016-2022)
13.5.2 Forecast Trend (2023-2031)
13.6 Others
14 Global Ankylosing Spondylitis Treatment Market Dynamics
14.1 Market Drivers and Constraints
14.2 SWOT Analysis
14.3 Porter’s Five Forces Model
14.4 Key Demand Indicators
14.5 Key Price Indicators
14.6 Industry Events, Initiatives & Trends
14.7 Value Chain Analysis
15 Supplier Landscape
15.1 Abvie, Inc.
15.1.1 Company Overview
15.1.2 Product Portfolio
15.1.3 Demographic Reach and Achievements
15.1.4 Mergers and Acquisitions
15.1.5 Certifications
15.2 Amgen Inc.
15.2.1 Company Overview
15.2.2 Product Portfolio
15.2.3 Demographic Reach and Achievements
15.2.4 Mergers and Acquisitions
15.2.5 Certifications
15.3 Eli Lilly & Company
15.3.1 Company Overview
15.3.2 Product Portfolio
15.3.3 Demographic Reach and Achievements
15.3.4 Mergers and Acquisitions
15.3.5 Certifications
15.4 Gilead Sciences
15.4.1 Company Overview
15.4.2 Product Portfolio
15.4.3 Demographic Reach and Achievements
15.4.4 Mergers and Acquisitions
15.4.5 Certifications
15.5 Johnson & Johnson (Janssen)
15.5.1 Company Overview
15.5.2 Product Portfolio
15.5.3 Demographic Reach and Achievements
15.5.4 Mergers and Acquisitions
15.5.5 Certifications
15.6 Pfizer Inc.
15.6.1 Company Overview
15.6.2 Product Portfolio
15.6.3 Demographic Reach and Achievements
15.6.4 Mergers and Acquisitions
15.6.5 Certifications
15.7 Novartis AG
15.7.1 Company Overview
15.7.2 Product Portfolio
15.7.3 Demographic Reach and Achievements
15.7.4 Mergers and Acquisitions
15.7.5 Certifications
16 Global Ankylosing Spondylitis Treatment Market- Drug Distribution Model (Additional Insight)
16.1 Overview
16.2 Potential Distributors
16.3 Key Parameters for Distribution Partner Assessment
17 Payment Methods (Additional Insight)
17.1 Government Funded
17.2 Private Insurance
17.3 Out-of-Pocket
*Additional insights provided are customizable as per client requirements.
Key Questions Answered in the Report
In 2022, the market attained a value of nearly USD 4.64 billion.
The market is projected to grow at a CAGR of 8.1% during the forecast period of 2023-2031.
The market is estimated to witness healthy growth during the forecast period of 2022-2031 to reach a value of USD 9.37 billion by 2031.
The growth of the market is driven by the rising prevalence of the disease caused by bad postures, low nutrition, as well as long hours of inactivity.
The rising availability of affordable physiotherapy is a key trend in the market.
Drug types available in the market include Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and TNF Inhibitors, among others.
Based on indication type, the market can be divided into reactive arthritis, psoriatic arthritis, IBD associated arthritis, juvenile spondyloarthropathy, and undifferentiated spondyloarthropathy, among others.
The treatment methods include physiotherapy and exercise, painkillers, biological treatments, corticosteroids, disease modifying anti rheumatic drugs (DMARDs), and surgery, among others.
The treatment is available on public and private channels.
The major regions in the market are North America, Latin America, the Middle East and Africa, Europe, and the Asia Pacific.
The major players in the market are Abvie, Inc., Amgen Inc., Eli Lilly & Company, Gilead Sciences, Johnson & Johnson (Janssen), Pfizer Inc., and Novartis AG, among others.
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