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Global Gene Therapy Market Share, Size, Analysis, Report: By Indication: Neurological Disorder, Oncological Disorders, Rare Diseases, Eye Disorders, Other; By Vector: Non-Viral Vector, Viral Vector; Regional Analysis; Market Dynamics: SWOT Analysis, Porter’s Five Forces Analysis; Competitive Landscape; Industry Events and Developments; 2023-2028
Global Gene Therapy Market Outlook
The global gene therapy market size reached a value of around USD 6.36 billion in 2022. The market is further estimated to grow in the forecast period of 2023-2028 at a CAGR of 22.80% to reach about USD 21.38 billion by 2028.
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The gene therapy market share is growing, supported by the increasing competition among major firms concentrating on the commercialisation of gene therapies, as well as the expansion of the field of advanced therapeutics and gene delivery technologies. Investments in acquisitions, mergers, and expansions are major methods used by biotechnology companies to strengthen their product pipelines and increase knowledge.
Also, increased funding and investments are anticipated to open up profitable growth potential for market participants in gene therapy. Recent years have seen a significant increase in the gene therapy market mainly due to the rapid technological advances in cellular and molecular biology and genomics research.
The gene therapy market growth is anticipated to be boosted throughout the forecast period by a strong gene therapy pipeline. Researchers are working to make gene therapies accessible in clinics. A wide range of products can be seen in the pipeline at various universities and institutes, which is projected to increase revenue generation in the near future.
Increasing Applications of Viral Vectors in Gene Therapy for the Treatment of Chronic Diseases Driving the Market Growth
The increasing applications of viral vectors in gene therapy for the treatment of neurological, metabolic, and neurodegeneration diseases are driving the segment growth. According to the gene therapy market report, viral vectors offer various favourable properties such as safety, low-toxicity, and excellent stability, due to which they are increasingly preferred in gene therapy. As adenoviruses have excellent DNA harbouring capacity, they are one of the most extensively applied viral vectors in gene therapy. They are also used for the development of vaccines and cancer therapies, hence fuelling the growth of the gene therapy market.
As per the gene therapy market forecast, viral vectors account for a significant share in the clinical trials of gene therapy owing to their efficiency to deliver genes to the target tissues/cells. The increasing regulatory approvals of gene therapy drugs based on viral vectors are further propelling the market. Over the forecast period, the emergence of Adeno-associated virus vectors (AAV) as a gene therapy platform for the treatment of neurological diseases is likely to propel the growth of the gene therapy global market.
North America Accounts for a Significant Share in the Market for Gene Therapy
The gene therapy market in North America is being driven by the growing healthcare expenditure in the region and a strong foothold of major biopharmaceutical companies focused on advancing gene therapy techniques. According to the gene therapy market research, the growing prevalence of health issues such as cancer and cystic fibrosis in the region is further propelling the demand for gene therapy. In addition, the surging initiation of gene therapy clinical trials in the region to develop effective treatments for chronic diseases is augmenting the market. Moreover, the introduction of various favourable initiatives by various governments to encourage innovations and advancements in gene therapy is likely to propel the market expansion. The surging approval rates of new gene therapies by regulatory authorities to expand therapeutic treatment choices are expected to further aid the cell and gene therapy market growth in the forecast period.
Market Segmentation
Gene therapy is defined as a medical approach that targets the genetic problem of a patient in order to treat or prevent diseases. In this treatment therapy, a person’s genetic make-up is altered or modified instead of using drugs or surgery. Several mechanisms, including the replacement of disease-causing genes, inactivation of a disease-causing gene, and introduction of a modified gene into the body, among others, are involved in this process.
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Based on indication, the market can be segmented into:
- Neurological Disorder
- Oncological Disorders
- Rare Diseases
- Eye Disorders
- Others
By vector, the market is divided into:
- Non-Viral Vector
- Oligonucleotides
- Others
- Viral Vector
- Retroviral Vectors
- Adeno-associated Viral Vectors
- Others
The EMR report looks into the regional markets of gene therapy like North America, Europe, the Asia Pacific, Latin America, and the Middle East and Africa.
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Emergence of Gene Therapy as a Promising Treatment Option for Various Diseases to Boost the Market Growth
The emergence of gene therapy techniques as a promising treatment option for various genetic diseases such as muscular dystrophy and cystic fibrosis, among others, is increasing the gene therapy market size. The emerging treatment modalities, such as immunotherapy and oncolytic virotherapy, are increasingly gaining traction in cancer treatments. In addition to this, the increasing prevalence of cancer, coupled with the robust research and development activities aimed at expanding cancer treatment options, is likely to accelerate the growth of the cancer gene therapy market in the coming years. As cancer treatment options based on gene therapy offer a high success rate and enhanced flexibility, the market is expected to witness a healthy growth.
According to the gene therapy market analysis, gene therapy offers possibilities of positive medical outcomes and can create permanent results, which is strengthening the market growth. Over the forecast period, the increasing approvals of various gene therapy medications by regulatory authorities like the Food and Drug Administration (FDA) of the United States are expected to bolster the gene therapies market growth. Moreover, the evolving patient preference toward minimally invasive treatment procedures for diseases like lymphoma and leukaemia, among others, is anticipated to propel the gene therapy market growth in the coming years.
Key Players in the Global Market for Gene Therapy
The report gives a detailed analysis of the following key players in the global gene therapy market, covering their competitive landscape, capacity, and latest developments like mergers, acquisitions, and investments, expansions of capacity, and plant turnarounds:
- Novartis AG
- Amgen Inc.
- bluebird bio, Inc.
- Biogen Inc.
- Sibiono GeneTech Co. Ltd.
- Gilead Sciences, Inc.
- Sangamo Therapeutics, Inc.
- Intellia Therapeutics, Inc.
- REGENXBIO Inc.
- Abeona Therapeutics Inc.
- Orchard Therapeutics plc
- Sio Gene Therapies Ltd.
- Ultragenyx Pharmaceutical Inc.
- Krystal Biotech, Inc.
- Rocket Pharmaceuticals, Ltd.
- MeiraGTx Limited.
- Solid Biosciences Inc.
- GenSight Biologics S.A.
- Editas Medicine, Inc.
- CRISPR Therapeutics AG
- Spark Therapeutics, Inc.
- Genprex, Inc.
- Poseida Therapeutics, Inc.
- Astellas Pharma Inc.
- Voyager Therapeutics, Inc.
- Coave Therapeutics
- Precision BioSciences, Inc.
- Others
The comprehensive EMR report provides an in-depth assessment of the market based on the Porter's five forces model along with giving a SWOT analysis.
Key Highlights of the Report
| REPORT FEATURES | DETAILS |
|---|---|
| Base Year | 2022 |
| Historical Period | 2018-2022 |
| Forecast Period | 2023-2028 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
|
| Breakup by Indication |
|
| Breakup by Vector |
|
| Breakup by Region |
|
| Market Dynamics |
|
| Competitive Landscape |
|
| Companies Covered |
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| Report Price and Purchase Option | Explore our purchase options that are best suited to your resources and industry needs. |
| Delivery Format | Delivered as an attached PDF and Excel through email, with an option of receiving an editable PPT, according to the purchase option. |
*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.
1 Preface
2 Report Coverage – Key Segmentation and Scope
3 Report Description
3.1 Market Definition and Outlook
3.2 Properties and Applications
3.3 Market Analysis
3.4 Key Players
4 Key Assumptions
5 Executive Summary
5.1 Overview
5.2 Key Drivers
5.3 Key Developments
5.4 Competitive Structure
5.5 Key Industrial Trends
6 Market Snapshot
6.1 Global
6.2 Regional
7 Opportunities and Challenges in the Market
8 Global Gene Therapy Market Analysis
8.1 Key Industry Highlights
8.2 Global Gene Therapy Historical Market (2018-2022)
8.3 Global Gene Therapy Market Forecast (2023-2028)
8.4 Global Gene Therapy Market by Indication
8.4.1 Neurological Disorder
8.4.1.1 Market Share
8.4.1.2 Historical Trend (2018-2022)
8.4.1.3 Forecast Trend (2023-2028)
8.4.2 Oncological Disorders
8.4.2.1 Market Share
8.4.2.2 Historical Trend (2018-2022)
8.4.2.3 Forecast Trend (2023-2028)
8.4.3 Rare Diseases
8.4.3.1 Market Share
8.4.3.2 Historical Trend (2018-2022)
8.4.3.3 Forecast Trend (2023-2028)
8.4.4 Eye Disorders
8.4.4.1 Market Share
8.4.4.2 Historical Trend (2018-2022)
8.4.4.3 Forecast Trend (2023-2028)
8.4.5 Other
8.5 Global Gene Therapy Market by Vector
8.5.1 Non-Viral Vector
8.5.1.1 Market Share
8.5.1.2 Historical Trend (2018-2022)
8.5.1.3 Forecast Trend (2023-2028)
8.5.1.4 Breakup by Type
8.5.1.4.1 Oligonucleotides
8.5.1.4.2 Others
8.5.2 Viral Vector
8.5.2.1 Market Share
8.5.2.2 Historical Trend (2018-2022)
8.5.2.3 Forecast Trend (2023-2028)
8.5.2.4 Breakup by Type
8.5.2.4.1 Retroviral Vectors
8.5.2.4.2 Adeno-associated Viral Vectors
8.5.2.4.3 Others
8.6 Global Gene Therapy Market by Region
8.6.1 North America
8.6.1.1 Market Share
8.6.1.2 Historical Trend (2018-2022)
8.6.1.3 Forecast Trend (2023-2028)
8.6.2 Europe
8.6.2.1 Market Share
8.6.2.2 Historical Trend (2018-2022)
8.6.2.3 Forecast Trend (2023-2028)
8.6.3 Asia Pacific
8.6.3.1 Market Share
8.6.3.2 Historical Trend (2018-2022)
8.6.3.3 Forecast Trend (2023-2028)
8.6.4 Latin America
8.6.4.1 Market Share
8.6.4.2 Historical Trend (2018-2022)
8.6.4.3 Forecast Trend (2023-2028)
8.6.5 Middle East and Africa
8.6.5.1 Market Share
8.6.5.2 Historical Trend (2018-2022)
8.6.5.3 Forecast Trend (2023-2028)
9 North America Gene Therapy Market Analysis
9.1 United States of America
9.1.1 Market Share
9.1.2 Historical Trend (2018-2022)
9.1.3 Forecast Trend (2023-2028)
9.2 Canada
9.2.1 Market Share
9.2.2 Historical Trend (2018-2022)
9.2.3 Forecast Trend (2023-2028)
10 Europe Gene Therapy Market Analysis
10.1 United Kingdom
10.1.1 Market Share
10.1.2 Historical Trend (2018-2022)
10.1.3 Forecast Trend (2023-2028)
10.2 Germany
10.2.1 Market Share
10.2.2 Historical Trend (2018-2022)
10.2.3 Forecast Trend (2023-2028)
10.3 France
10.3.1 Market Share
10.3.2 Historical Trend (2018-2022)
10.3.3 Forecast Trend (2023-2028)
10.4 Italy
10.4.1 Market Share
10.4.2 Historical Trend (2018-2022)
10.4.3 Forecast Trend (2023-2028)
10.5 Others
11 Asia Pacific Gene Therapy Market Analysis
11.1 China
11.1.1 Market Share
11.1.2 Historical Trend (2018-2022)
11.1.3 Forecast Trend (2023-2028)
11.2 Japan
11.2.1 Market Share
11.2.2 Historical Trend (2018-2022)
11.2.3 Forecast Trend (2023-2028)
11.3 India
11.3.1 Market Share
11.3.2 Historical Trend (2018-2022)
11.3.3 Forecast Trend (2023-2028)
11.4 ASEAN
11.4.1 Market Share
11.4.2 Historical Trend (2018-2022)
11.4.3 Forecast Trend (2023-2028)
11.5 Australia
11.5.1 Market Share
11.5.2 Historical Trend (2018-2022)
11.5.3 Forecast Trend (2023-2028)
11.6 Others
12 Latin America Gene Therapy Market Analysis
12.1 Brazil
12.1.1 Market Share
12.1.2 Historical Trend (2018-2022)
12.1.3 Forecast Trend (2023-2028)
12.2 Argentina
12.2.1 Market Share
12.2.2 Historical Trend (2018-2022)
12.2.3 Forecast Trend (2023-2028)
12.3 Mexico
12.3.1 Market Share
12.3.2 Historical Trend (2018-2022)
12.3.3 Forecast Trend (2023-2028)
12.4 Others
13 Middle East and Africa Gene Therapy Market Analysis
13.1 Saudi Arabia
13.1.1 Market Share
13.1.2 Historical Trend (2018-2022)
13.1.3 Forecast Trend (2023-2028)
13.2 United Arab Emirates
13.2.1 Market Share
13.2.2 Historical Trend (2018-2022)
13.2.3 Forecast Trend (2023-2028)
13.3 Nigeria
13.3.1 Market Share
13.3.2 Historical Trend (2018-2022)
13.3.3 Forecast Trend (2023-2028)
13.4 South Africa
13.4.1 Market Share
13.4.2 Historical Trend (2018-2022)
13.4.3 Forecast Trend (2023-2028)
13.5 Others
14 Market Dynamics
14.1 SWOT Analysis
14.1.1 Strengths
14.1.2 Weaknesses
14.1.3 Opportunities
14.1.4 Threats
14.2 Porter’s Five Forces Analysis
14.2.1 Supplier’s Power
14.2.2 Buyer’s Power
14.2.3 Threat of New Entrants
14.2.4 Degree of Rivalry
14.2.5 Threat of Substitutes
14.3 Key Indicators for Demand
14.4 Key Indicators for Price
15 Competitive Landscape
15.1 Market Structure
15.2 Company Profiles
15.2.1 Novartis AG
15.2.1.1 Company Overview
15.2.1.2 Product Portfolio
15.2.1.3 Demographic Reach and Achievements
15.2.1.4 Certifications
15.2.2 Amgen Inc.
15.2.2.1 Company Overview
15.2.2.2 Product Portfolio
15.2.2.3 Demographic Reach and Achievements
15.2.2.4 Certifications
15.2.3 bluebird bio, Inc.
15.2.3.1 Company Overview
15.2.3.2 Product Portfolio
15.2.3.3 Demographic Reach and Achievements
15.2.3.4 Certifications
15.2.4 Biogen Inc.
15.2.4.1 Company Overview
15.2.4.2 Product Portfolio
15.2.4.3 Demographic Reach and Achievements
15.2.4.4 Certifications
15.2.5 Sibiono GeneTech Co. Ltd.
15.2.5.1 Company Overview
15.2.5.2 Product Portfolio
15.2.5.3 Demographic Reach and Achievements
15.2.5.4 Certifications
15.2.6 Others
16 Key Trends and Developments in the Market
List of Key Figures and Tables
1. Global Gene Therapy Market: Key Industry Highlights, 2018 and 2028
2. Global Gene Therapy Historical Market: Breakup by Indication (USD Billion), 2018-2022
3. Global Gene Therapy Market Forecast: Breakup by Indication (USD Billion), 2023-2028
4. Global Gene Therapy Historical Market: Breakup by Vector (USD Billion), 2018-2022
5. Global Gene Therapy Market Forecast: Breakup by Vector (USD Billion), 2023-2028
6. Global Gene Therapy Historical Market: Breakup by Region (USD Billion), 2018-2022
7. Global Gene Therapy Market Forecast: Breakup by Region (USD Billion), 2023-2028
8. North America Gene Therapy Historical Market: Breakup by Country (USD Billion), 2018-2022
9. North America Gene Therapy Market Forecast: Breakup by Country (USD Billion), 2023-2028
10. Europe Gene Therapy Historical Market: Breakup by Country (USD Billion), 2018-2022
11. Europe Gene Therapy Market Forecast: Breakup by Country (USD Billion), 2023-2028
12. Asia Pacific Gene Therapy Historical Market: Breakup by Country (USD Billion), 2018-2022
13. Asia Pacific Gene Therapy Market Forecast: Breakup by Country (USD Billion), 2023-2028
14. Latin America Gene Therapy Historical Market: Breakup by Country (USD Billion), 2018-2022
15. Latin America Gene Therapy Market Forecast: Breakup by Country (USD Billion), 2023-2028
16. Middle East and Africa Gene Therapy Historical Market: Breakup by Country (USD Billion), 2018-2022
17. Middle East and Africa Gene Therapy Market Forecast: Breakup by Country (USD Billion), 2023-2028
18. Global Gene Therapy Market Structure
Key Questions Answered in the Report
In 2022, the global gene therapy market attained a value of nearly USD 6.36 billion.
The market is estimated to grow at a CAGR of 22.80% between 2023 and 2028.
The market is estimated to witness a healthy growth in the forecast period of 2023-2028 to reach about USD 21.38 billion by 2028.
The major regions in the market are North America, Latin America, the Middle East and Africa, Europe, and the Asia Pacific.
The major drivers of the market include the increasing prevalence of chronic diseases, the growing approvals of gene therapy medications by health authorities, and the increasing inclination towards minimally invasive treatment procedures.
The growing research and development (R&D) activities by the major biopharmaceutical companies to expand gene therapy treatment options, the surging prevalence of cancer, and the growing initiation of gene therapy clinical trials.
Neurological disorder, oncological disorders, rare diseases, and eye disorders, among others, are the different indication segments of gene therapy.
Non-viral vector and viral vector are the significant vectors of gene therapy in the market.
The major players in the market are Novartis AG, Amgen Inc., bluebird bio, Inc., Biogen Inc., Sibiono GeneTech Co. Ltd., Gilead Sciences, Inc., Sangamo Therapeutics, Inc., Intellia Therapeutics, Inc., REGENXBIO Inc., Abeona Therapeutics Inc., Orchard Therapeutics plc, Sio Gene Therapies Ltd., Ultragenyx Pharmaceutical Inc., Krystal Biotech, Inc., Rocket Pharmaceuticals, Ltd., MeiraGTx Limited., Solid Biosciences Inc., GenSight Biologics S.A., Editas Medicine, Inc., CRISPR Therapeutics AG, Spark Therapeutics, Inc., Genprex, Inc., Poseida Therapeutics, Inc., Astellas Pharma Inc., Voyager Therapeutics, Inc., Coave Therapeutics, and Precision BioSciences, Inc., among others.
Analyst Review
The global gene therapy market reached a value of about USD 6.36 billion in 2022, driven by the rising healthcare expenditure. Aided by the growing research and development (R&D) activities to expand gene therapy treatment options, the market is estimated to witness a further growth in the forecast period of 2023-2028, growing at a CAGR of 22.80%, to reach a value of nearly USD 21.38 billion by 2028.
EMR’s meticulous research methodology delves deep into the market, covering the macro and micro aspects of the market. Based on indication, the market for gene therapy is segmented into neurological disorder, oncological disorders, rare diseases, and eye disorders, among others. On the basis of vector, the market is bifurcated into non-viral vector and viral vector. The major regional markets for gene therapy are North America, Europe, the Asia Pacific, Latin America, and the Middle East and Africa. The key players in the above market include Novartis AG, Amgen Inc., bluebird bio, Inc., Biogen Inc., Sibiono GeneTech Co. Ltd., Gilead Sciences, Inc., Sangamo Therapeutics, Inc., Intellia Therapeutics, Inc., REGENXBIO Inc., Abeona Therapeutics Inc., Orchard Therapeutics plc, Sio Gene Therapies Ltd., Ultragenyx Pharmaceutical Inc., Krystal Biotech, Inc., Rocket Pharmaceuticals, Ltd., MeiraGTx Limited., Solid Biosciences Inc., GenSight Biologics S.A., Editas Medicine, Inc., CRISPR Therapeutics AG, Spark Therapeutics, Inc., Genprex, Inc., Poseida Therapeutics, Inc., Astellas Pharma Inc., Voyager Therapeutics, Inc., Coave Therapeutics, and Precision BioSciences, Inc., among others.
EMR’s research methodology uses a combination of cutting-edge analytical tools and the expertise of their highly accomplished team, thus, providing their customers with market insights that are accurate, actionable, and help them remain ahead of their competition.
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