The global healthcare cold chain logistics market was valued at USD 62.50 Billion in 2025 and is expected to grow at a CAGR of 9.30%, reaching USD 152.08 Billion by 2035. The market growth is supported by the increasing demand for temperature-sensitive pharmaceuticals and vaccines, along with advancements in real-time monitoring and tracking technologies. Growing investments in cold storage infrastructure and expansion of distribution networks are enhancing efficiency and reliability. Rising focus on regulatory compliance and the expansion of biologics and personalized medicines are also expected to drive market growth in the forecast period.
Base Year
Historical Period
Forecast Period
In May 2025, DP World inaugurated a 1,10,000 sq. ft. cold chain facility in India, enhancing temperature-controlled logistics for pharmaceuticals and FMCG. Such infrastructure expansion is expected to significantly drive market growth by improving supply chain efficiency and reliability.
One of the major market trends includes the adoption of advanced digital monitoring solutions in cold chain logistics. For instance, in June 2024, Overhaul launched its Cold Chain Quality Solution to enhance real-time visibility, reduce spoilage, and improve supply chain efficiency.
Rising demand for temperature-sensitive pharmaceuticals and biologics is driving strong market growth, supported by major players’ continuous advancements in storage, packaging, and transportation technologies, ensuring product safety and regulatory compliance.
Compound Annual Growth Rate
9.3%
Value in USD Billion
2026-2035
*this image is indicative*
Healthcare cold chain logistics play a critical role in maintaining the integrity and efficacy of temperature-sensitive medical products, including vaccines, biologics, and pharmaceuticals, during transportation and storage. Efficient temperature-controlled systems ensure compliance with regulatory standards and minimize product spoilage, supporting safe patient care. The market was valued at USD 62.50 Billion in 2025 and has experienced significant growth due to rising demand for biologics, increasing global vaccine distribution, and technological advancements in refrigeration, tracking, and monitoring systems. Expansion of healthcare infrastructure and stringent regulatory requirements continue to drive the adoption of advanced cold chain solutions across multiple regions.
Innovative Portable Cold Chain Solutions to Drive the Market Expansion
The growing demand for reliable last-mile delivery of temperature-sensitive medical supplies is a significant driver of growth in the market. In October 2024, a Bengaluru-based start-up, Enhance Innovations, introduced Phloton, a portable battery-powered cooling device designed to transport vaccines and diagnostic samples to remote areas with limited electricity access. This solution addresses critical challenges in regions with high ambient temperatures, ensuring the integrity of medical products. Such advancements in portable cold chain technologies are expected to enhance distribution efficiency and contribute substantially to overall market growth.
Some of the key market trends include the expansion of advanced cold chain infrastructure and the growing investments in temperature-controlled logistics.
Expansion of Advanced Cold Chain Infrastructure to Elevate the Market Growth
The healthcare cold chain logistics sector is witnessing accelerated growth due to strategic investments in specialized facilities and advanced infrastructure. In April 2025, DHL Supply Chain inaugurated a new Pharma Hub in Singapore, part of a EUR 500 million Asia Pacific investment aimed at strengthening Life Sciences and Healthcare logistics capabilities. The 8,200-square-meter facility features GMP-compliant and temperature-controlled zones for ensuring precise handling of sensitive pharmaceuticals. With enhanced regional connectivity and innovative solutions, such initiatives are supporting faster, reliable deliveries. This trend is expected to bolster market resilience and drive sustained growth in healthcare logistics.
Rising Investments in Temperature-Controlled Logistics to Strengthen the Healthcare Cold Chain Logistics Market Value
A growing focus on advanced cold chain logistics is driving significant infrastructure investments across the healthcare logistics sector. In July 2024, UPS Healthcare announced an investment exceeding EUR 20 million to expand its temperature-controlled fleet in Europe, adding over 200 state-of-the-art vehicles. This initiative enhances the company’s ability to support the increasing demand for secure biologic and specialty pharmaceutical transport. Such large-scale investments in reliable, dual-temperature solutions and digital quality systems are reinforcing supply chain efficiency and are likely to significantly enhance market growth.
Transportation Services Expected to Lead Market Share by Service Type
The market comprises various service types, including storage, transportation, packaging, along with monitoring and data logging services, each addressing essential requirements for temperature-sensitive pharmaceutical logistics. Among these, transportation services are expected to lead the market, driven by rising demand for rapid, reliable, and compliant delivery solutions. Notably, in February 2025, UPS Healthcare launched specialized cross-docking facilities in Milan, Frankfurt, and Mexico City to strengthen cold chain transportation. This highlights the increasing focus on efficient and secure logistics for life-saving pharmaceutical products.
The market is divided into regions such as North America, Europe, Asia Pacific, Latin America, the Middle East and Africa. North America is poised to lead the market, driven by strategic initiatives such as the partnership between Frontier Scientific Solutions and Air Transport Services Group (ATSG). Announced in October, 2025, this collaboration aims to establish a dedicated air corridor for temperature-controlled pharmaceuticals, enhancing logistics efficiency and regulatory compliance. The initiative is further supported by a USD 1.5 billion investment from GID, focusing on infrastructure development and network expansion to create a high-integrity logistics platform serving leading life science markets worldwide.
The key features of the market report comprise funding and investment analysis, and strategic initiatives by the leading players. The major companies in the market are as follows:
Cardinal Health is a leading healthcare services and products company focused on maintaining supply chain integrity and patient safety. The company offers refrigerated pharmaceutical tote packaging and phase-change panels designed to maintain labeled storage temperature ranges during transportation. These solutions support safe delivery and return of temperature-sensitive pharmaceuticals, including vaccines, and demonstrate Cardinal Health’s active involvement in the healthcare cold chain logistics market.
DHL Group, through its DHL Supply Chain and Global Forwarding divisions, provides specialized logistics solutions for the healthcare sector. The company offers end-to-end services across pharmaceuticals, specialty pharma, medical devices, clinical trials, and consumer healthcare. With over 250 GDP-qualified warehouses, 120 life sciences-certified freight stations, and an extensive global network, DHL ensures temperature-controlled, compliant, and timely delivery of sensitive healthcare products. Its advanced cold chain capabilities and integrated logistics expertise position the company as a key player in supporting efficient and resilient healthcare supply chains.
UPS Healthcare is a leading provider in cold chain logistics, offering technology-driven solutions for the safe transport of pharmaceuticals, biologics, and laboratory specimens. The company delivers end-to-end cold chain services, including temperature-controlled storage, freight, packaging, and advanced visibility monitoring through UPS® Premier. Its solutions cover a wide temperature range, from controlled room temperature to ultra-frozen and cryogenic shipments, supporting the distribution of vaccines, specialty pharmaceuticals, cell and gene therapies, and other critical healthcare products.
FedEx Logistics is a global provider of specialized transportation and supply chain solutions, focusing on healthcare and life sciences. The company offers temperature-controlled shipping, insulated packaging, and real-time monitoring to ensure the safe delivery of sensitive medical products, including pharmaceuticals, vaccines, clinical trial materials, diagnostics, and medical equipment. FedEx’s services, such as FedEx Clinical Care and FedEx Custom Critical, enable efficient, compliant, and reliable movement of critical healthcare goods, demonstrating its active involvement in the healthcare cold chain logistics market.
*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*
Other key players in the market include CEVA Logistics, Agility Logistics, Lineage Logistics, Nippon Express, SF Express, and AirBridgeCargo Airlines.
The market report offers a detailed analysis of the market based on the following segments:
Market Breakup by Service Type
Market Breakup by Product Type
Market Breakup by Temperature Range
Market Breakup by Mode of Transportation
Market Breakup by End User
Market Breakup by Region
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*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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| REPORT FEATURES | DETAILS |
| Base Year | 2025 |
| Historical Period | 2019-2025 |
| Forecast Period | 2026-2035 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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| Breakup by Service Type |
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| Breakup by Product Type |
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| Breakup by Temperature Range |
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| Breakup by Mode of Transportation |
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| Breakup by End User |
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| Breakup by Region |
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| Market Dynamics |
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| Supplier Landscape |
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| Companies Covered |
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