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Knee Cartilage Repair Market

Global Knee Cartilage Repair Market Size, Growth, Share, Report, Forecast: By Treatment Modality: Cell-based, Noncell- Based; By Surgery: Osteochondral Autograft Transplantation, Osteochondral Allograft Transplantation, Microfracture, Drilling, Others; By Devices; By Application; By End User; Regional Analysis; Supplier Landscape; 2024-2032

Global Knee Cartilage Repair Market Outlook

The global knee cartilage repair market size attained a value of about USD 2.99 billion in 2023, driven by the rising demand of minimally invasive knee surgeries across the globe. The market value is anticipated to grow at a CAGR of 6.2% during the forecast period of 2024-2032 to attain a market value of USD 5.15 billion by 2032.

 

Global Knee Cartilage Repair Market

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Global Knee Cartilage Repair Market Likely to be Driven by Demand for Treatment Options for Rising Instances of Knee Problems

In orthopaedics, articular cartilage injuries are a serious clinical concern. With high incidence of injury and limited intrinsic tissue repair potential, a large population of youthful and healthy individuals are left in danger of developing degenerative osteoarthritis (OA). It is estimated that over 30% of Americans above 45 years of age experience some type of knee pain.

Cartilage is a type of connective tissue found in several parts of the body. It is relatively easy to damage, despite being a robust and flexible material.

Chondral lesions are a common occurrence in a significant majority of the population. Chondroplasty is a common procedure performed to treat chondral injuries. It involves the removal of damaged tissue. While this approach offers symptomatic relief in the short-run, the remaining tissue becomes more prone to deterioration and faster degeneration.

Microfracture, which entails piercing the subchondral bone to enable the bone marrow to plug the defect, is another prevalent procedure. However, it leads to the creation of mechanically inferior fibrocartilage tissue.

Mosaicplasty, also known as osteochondral autologous transplantation (OATs), is an open treatment that involves harvesting osteochondral plugs from non-weight-bearing areas and transplanting them into the deficiency. However, transplanted cartilage has been shown to produce donor site morbidity; it does not combine well with existing cartilage, and degenerates with time.

Modern cartilage regeneration techniques include autologous chondrocyte implantation (ACI), matrix-associated autologous chondrocyte implantation (MACI), and autologous matrix-induced chondrogenesis (AMIC).

In the MACI technique, a two-stage procedure is followed. It is an advancement of the ACI approach. Healthy cartilage cells are extracted from the patient, then expanded and seeded in a collagen matrix; these are then re-implanted into the cartilage defect.

AMIC is a single-stage treatment that involves implanting a cell-free collagen matrix into a cartilage defect and then microfracturing it.

While these treatment options have provided better outcomes than conventional techniques such as chondroplasty and microfracture, they largely remain limited to a minority of the patient population with close to ideal surgical conditions. Such patients are most likely to benefit significantly after an intervention. The larger population with more severe symptoms, or those who suffer from co-morbidities precluding them from these cartilage repair interventions are limited to short-term palliative treatment alternatives, such as oral non-steroidal anti-inflammatory drugs (NSAIDs) or intra-articular injections of corticosteroids or hyaluronic acid. Although these treatments offer short-term relief from pain and inflammation, the long-term solution for such patients seems to be total joint replacement.

 

Innovative Solutions by Leading Companies Expected to Stimulate the Market

Several leading companies such as Stryker Corporation, Smith and Nephew, Vericel Corporation are engaged in providing treatment solutions for joint problems. In 2017, Vericel Corporation announced the first MACI implant in USA to repair symptomatic single or multiple full-thickness cartilage defects of the knee with or without bone involvement in adults. Smith and Nehphew offer CARGEL Bioscaffold - an easy, ready-to-use product employed in a single-step bone marrow stimulation procedure to provide superior cartilage repair. Stryker Corporation introduced a cementless total knee system - cementless total knee arthroplasty (TKA) with Triathlon Tritanium – that is becoming quite popular. The system has been reported to deliver good clinical outcomes and significant pain reduction. Such advancements in treatment systems are expected to boost the market. North America, Europe and Asia Pacific are expected to be key markets.

 

Global Knee Cartilage Repair Market Segmentation

 

Global Knee Cartilage Repair Market By Segment

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By modality, the market is segmented into:

  • Cell-Based (further broken down by type as given below)
    • Chondrocyte Transplantation
    • Growth Factor Technology
  • Non-Cell Based (further broken down by type as given below)
    • Tissue Scaffolds
    • Cell-Free Composites

By treatment type, the market is classified into:

  • Palliative (further broken down by type as given below)
    • Viscosupplementation
    • Debridement and Lavage
  • Intrinsic Repair Stimulus

By end-user, the market is divided into:

  • Hospitals 
  • Ambulatory Surgical Centers
  • Orthopaedic Clinics
  • Others

By region, the market is segmented into:

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa

 

Global Knee Cartilage Repair Market By Region

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Key Industry Players in the Global Knee Cartilage Repair Market

The report presents a detailed analysis of the following key players in the market, looking into their capacity, and latest developments like capacity expansions, plant turnarounds, and mergers and acquisitions:

  • Stryker
  • Zimmer Biomet
  • B. Braun Melsungen AG
  • The Future of Biotechnology
  • MEDIPOST
  • Vericel Corporation
  • CONMED Corporation
  • Meril Life Sciences Pvt. Ltd.
  • Medacta International
  • Teijin Nakashima Medical Co., Ltd.
  • EVOLUTIS INDIA PVT. LTD.
  • Regentis Biomaterials Ltd.
  • Auxein Medical.

The EMR report gives an in-depth insight into the industry by providing a SWOT analysis as well as an analysis of Porter’s Five Forces model.

 

Key Highlights of the Report

REPORT FEATURES DETAILS
Base Year 2023
Historical Period 2017-2023
Forecast Period 2024-2032
Scope of the Report

Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:

  • Treatment Modality
  • Surgery
  • Devices
  • Application
  • End User
  • Region
Breakup by Treatment Modality
  • Cell-based
  • Noncell- Based
Breakup by Surgery
  • Osteochondral Autograft Transplantation
  • Osteochondral Allograft Transplantation
  • Microfracture
  • Drilling
  • Abrasion Arthroplasty
  • Autologous Chondrocyte Implantation
  • Others
Breakup by Devices
  • Implants
  • Osteotomy
  • Bone Grafts
  • Arthroscopy
  • Resurfacing
  • Arthrodesis
  • Others
Breakup by Application
  • Osteoarthritis
  • Rheumatoid Arthritis
  • Osteonecrosis
  • Fractures
  • Bone Tumors
  • Others
Breakup by End User
  • Hospitals
  • Orthopedic Centres
  • Ambulatory Surgical Centres
  • Others
Breakup by Region
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa
Market Dynamics
  • Market Drivers and Constraints
  • SWOT Analysis
  • Porter's Five Forces Analysis
  • Key Indicators for Demand
  • Key Indicators for Price
  • Industry Events, Initiatives, and Trends
  • Value Chain Analysis
Competitive Landscape
  • Market Structure
  • Company Profiles
    • Company Overview
    • Product Portfolio
    • Demographic Reach and Achievements
    • Mergers and Acquisitions
    • Certifications
Companies Covered
  • Stryker
  • Zimmer Biomet
  • B. Braun Melsungen AG
  • The Future of Biotechnology
  • MEDIPOST
  • Vericel Corporation
  • CONMED Corporation
  • Meril Life Sciences Pvt. Ltd.
  • Medacta International
  • Teijin Nakashima Medical Co., Ltd.
  • EVOLUTIS INDIA PVT. LTD.
  • Regentis Biomaterials Ltd.
  • Auxein Medical.
Report Price and Purchase Option Explore our purchase options that are best suited to your resources and industry needs.
Delivery Format Delivered as an attached PDF and Excel through email, with an option of receiving an editable PPT, according to the purchase option.

 

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.

1    Preface
    1.1    Objectives of the Study
    1.2    Key Assumptions
    1.3    Report Coverage – Key Segmentation and Scope 
    1.4    Research Methodology
2    Executive Summary
3    Knee Cartilage Overview

    3.1    Guidelines and Stages
    3.2    Pathophysiology
    3.3    Screening and Diagnosis
    3.4    Treatment Pathway 
4    Patient Profile
    4.1    Patient Profile Overview
    4.2    Patient Psychology and Emotional Impact Factors
    4.3    Risk Assessment and Treatment Success Rate
5    Knee Osteoarthritis Epidemiology Analysis
    5.1    Epidemiology Overview (2016-2031)
    5.2    North America Knee Osteoarthritis Epidemiology (2016-2031)
    5.3    Europe Knee Osteoarthritis Epidemiology (2016-2031)
    5.4    Asia-Pacific Knee Osteoarthritis Epidemiology (2016-2031)
    5.5    Latin America Knee Osteoarthritis Epidemiology (2016-2031)
    5.6    Middle East & Africa Knee Osteoarthritis Epidemiology (2016-2031)
6    Global Knee Cartilage Repair Market Overview 
    6.1    Global Knee Cartilage Repair Market Historical Value (2017-2023) 
    6.2    Global Knee Cartilage Repair Market Forecast Value (2024-2032)
7    Global Knee Cartilage Repair Market Landscape
    7.1    Knee Cartilage Repair: Developers Landscape
        7.1.1    Analysis by Year of Establishment
        7.1.2    Analysis by Company Size
        7.1.3    Analysis by Region
    7.2    Knee Cartilage Repair: Product Landscape
        7.2.1    Analysis by Treatment Modality
        7.2.2    Analysis by Surgery
        7.2.3    Analysis by Devices
        7.2.4    Analysis by Application
        7.2.5    Analysis by End User
8    Knee Cartilage Repair Challenges and Unmet Needs
    8.1    Treatment Pathway Challenges
    8.2    Compliance and Drop-Out Analysis
    8.3    Awareness and Prevention Gaps
9    Cost of Treatment
10    Global Knee Cartilage Repair Market Dynamics

    10.1    Market Drivers and Constraints
    10.2    SWOT Analysis
    10.3    Porter’s Five Forces Model
    10.4    Key Demand Indicators 
    10.5    Key Price Indicators
    10.6    Industry Events, Initiatives, and Trends  
    10.7    Value Chain Analysis
11    Global Knee Cartilage Repair Market Segmentation
    11.1    Global Knee Cartilage Repair Market by Treatment Modality
        11.1.1    Market Overview
        11.1.2    Cell-based
            11.1.2.1    Chondrocyte Transplantation
            11.1.2.2    Growth Factor Technology
        11.1.3    Noncell- Based
            11.1.3.1    Tissue Scaffolds
            11.1.3.2    Cell-Free Composites
    11.2    Global Knee Cartilage Repair Market by Surgery
        11.2.1    Market Overview
            11.2.1.1    Osteochondral Autograft Transplantation
            11.2.1.2    Osteochondral Allograft Transplantation
            11.2.1.3    Microfracture
            11.2.1.4    Drilling
            11.2.1.5    Abrasion Arthroplasty
            11.2.1.6    Autologous Chondrocyte Implantation
            11.2.1.7    Others
    11.3    Global Knee Cartilage Repair Market by Devices
        11.3.1    Market Overview
        11.3.2    Implants
        11.3.3    Osteotomy
        11.3.4    Bone Grafts
        11.3.5    Arthroscopy
        11.3.6    Resurfacing
        11.3.7    Arthrodesis
        11.3.8    Others
    11.4    Global Knee Cartilage Repair Market by Application
        11.4.1    Market Overview
        11.4.2    Osteoarthritis
        11.4.3    Rheumatoid Arthritis
        11.4.4    Osteonecrosis
        11.4.5    Fractures
        11.4.6    Bone Tumors
        11.4.7    Others
    11.5    Global Knee Cartilage Repair Market by End User
        11.5.1    Market Overview
        11.5.2    Hospitals
        11.5.3    Orthopedic Centres
        11.5.4    Ambulatory Surgical Centres
        11.5.5    Others
    11.6    Global Knee Cartilage Repair Market by Region
        11.6.1    Market Overview
        11.6.2    North America
        11.6.3    Europe 
        11.6.4    Asia Pacific
        11.6.5    Latin America
        11.6.6    Middle East and Africa
12    North America Knee Cartilage Repair Market
    12.1    Market Share by Country
    12.2    United States of America
    12.3    Canada
13    Europe Knee Cartilage Repair Market
    13.1    Market Share by Country
    13.2    United Kingdom
    13.3    Germany
    13.4    France
    13.5    Italy
    13.6    Others
14    Asia Pacific Knee Cartilage Repair Market
    14.1    Market Share by Country
    14.2    China
    14.3    Japan
    14.4    India
    14.5    ASEAN
    14.6    Australia
    14.7    Others
15    Latin America Knee Cartilage Repair Market
    15.1    Market Share by Country
    15.2    Brazil
    15.3    Argentina
    15.4    Mexico
    15.5    Others
16    Middle East and Africa Knee Cartilage Repair Market
    16.1    Market Share by Country
    16.2    Saudi Arabia
    16.3    United Arab Emirates
    16.4    Nigeria
    16.5    South Africa
    16.6    Others
17    Regulatory Framework
    17.1    Regulatory Overview
        17.1.1    US FDA
        17.1.2    EU EMA
        17.1.3    INDIA CDSCO
        17.1.4    JAPAN PMDA
        17.1.5    Others
18    Patent Analysis
    18.1    Analysis by Type of Patent
    18.2    Analysis by Publication year
    18.3    Analysis by Issuing Authority
    18.4    Analysis by Patent Age
    18.5    Analysis by CPC Analysis
    18.6    Analysis by Patent Valuation 
    18.7    Analysis by Key Players
19    Grants Analysis
    19.1    Analysis by year
    19.2    Analysis by Amount Awarded
    19.3    Analysis by Issuing Authority
    19.4    Analysis by Grant Application
    19.5    Analysis by Funding Institute
    19.6    Analysis by NIH Departments
    19.7    Analysis by Recipient Organization 
20    Clinical Trials Analysis
    20.1     Analysis by Trial Registration Year
    20.2    Analysis by Trial Status
    20.3    Analysis by Trial Phase
    20.4    Analysis by Therapeutic Area
    20.5    Analysis by Geography
21    Funding and Investment Analysis
    21.1    Analysis by Funding Instances
    21.2    Analysis by Type of Funding
    21.3    Analysis by Funding Amount
    21.4    Analysis by Leading Players
    21.5    Analysis by Leading Investors
    21.6    Analysis by Geography
22    Partnership and Collaborations Analysis
    22.1    Analysis by Partnership Instances
    22.2    Analysis by Type of Partnership
    22.3    Analysis by Leading Players
    22.4    Analysis by Geography
23    Supplier Landscape
    23.1    Stryker
        23.1.1    Financial Analysis
        23.1.2    Product Portfolio
        23.1.3    Demographic Reach and Achievements
        23.1.4    Mergers and Acquisitions
        23.1.5    Certifications
    23.2    Zimmer Biomet
        23.2.1    Financial Analysis
        23.2.2    Product Portfolio
        23.2.3    Demographic Reach and Achievements
        23.2.4    Mergers and Acquisitions
        23.2.5    Certifications
    23.3    B. Braun Melsungen AG
        23.3.1    Financial Analysis
        23.3.2    Product Portfolio
        23.3.3    Demographic Reach and Achievements
        23.3.4    Mergers and Acquisitions
        23.3.5    Certifications
    23.4    The Future of Biotechnology
        23.4.1    Financial Analysis
        23.4.2    Product Portfolio
        23.4.3    Demographic Reach and Achievements
        23.4.4    Mergers and Acquisitions
        23.4.5    Certifications
    23.5    MEDIPOST
        23.5.1    Financial Analysis
        23.5.2    Product Portfolio
        23.5.3    Demographic Reach and Achievements
        23.5.4    Mergers and Acquisitions
        23.5.5    Certifications
    23.6    Vericel Corporation
        23.6.1    Financial Analysis
        23.6.2    Product Portfolio
        23.6.3    Demographic Reach and Achievements
        23.6.4    Mergers and Acquisitions
        23.6.5    Certifications
    23.7    CONMED Corporation
        23.7.1    Financial Analysis
        23.7.2    Product Portfolio
        23.7.3    Demographic Reach and Achievements
        23.7.4    Mergers and Acquisitions
        23.7.5    Certifications
    23.8    Meril Life Sciences Pvt. Ltd.
        23.8.1    Financial Analysis
        23.8.2    Product Portfolio
        23.8.3    Demographic Reach and Achievements
        23.8.4    Mergers and Acquisitions
        23.8.5    Certifications
    23.9    Medacta International
        23.9.1    Financial Analysis
        23.9.2    Product Portfolio
        23.9.3    Demographic Reach and Achievements
        23.9.4    Mergers and Acquisitions
        23.9.5    Certifications
    23.10    Teijin Nakashima Medical Co., Ltd.
        23.10.1    Financial Analysis
        23.10.2    Product Portfolio
        23.10.3    Demographic Reach and Achievements
        23.10.4    Mergers and Acquisitions
        23.10.5    Certifications 
    23.11    EVOLUTIS INDIA PVT.   LTD.
        23.11.1    Financial Analysis
        23.11.2    Product Portfolio
        23.11.3    Demographic Reach and Achievements
        23.11.4    Mergers and Acquisitions
        23.11.5    Certifications
    23.12    Regentis Biomaterials Ltd.
        23.12.1    Financial Analysis
        23.12.2    Product Portfolio
        23.12.3    Demographic Reach and Achievements
        23.12.4    Mergers and Acquisitions
        23.12.5    Certifications
    23.13    Auxein Medical.
        23.13.1    Financial Analysis
        23.13.2    Product Portfolio
        23.13.3    Demographic Reach and Achievements
        23.13.4    Mergers and Acquisitions
        23.13.5    Certifications
24    Knee Cartilage Repair - Distribution Model (Additional Insight)
    24.1    Overview 
    24.2    Potential Distributors 
    24.3    Key Parameters for Distribution Partner Assessment 
25    Key Opinion Leaders (KOL) Insights (Additional Insight)
26    Company Competitiveness Analysis (Additional Insight)

    26.1    Very Small Companies
    26.2    Small Companies
    26.3    Mid-Sized Companies
    26.4    Large Companies
    26.5    Very Large Companies
27    Payment Methods (Additional Insight)
    27.1    Government Funded
    27.2    Private Insurance
    27.3    Out-of-Pocket


*Additional insights provided are customisable as per client requirements.

Key Questions Answered in the Report

The market is estimated to grow at a CAGR of 6.2% between 2024 and 2032.

The major drivers of the market include the rising cases of injuries and accidents, rising healthcare expenditure, growing health awareness, susceptibility of knee damage among the geriatrics, and rapid development of hospitals, nursing homes, and clinics.

The technological advancements in the healthcare sector are expected to be a key trend guiding the growth of the industry.

The major regions in the industry are North America, Latin America, the Middle East and Africa, Europe, and the Asia Pacific.

Cell-based and non-cell based are the different treatment modalities considered in the market report.

Palliative and intrinsic repair stimulus are the significant treatment types included in the market report.

Hospitals, ambulatory surgical centers, and orthopaedic clinics, among others are the major end users of the product.

The major players in the industry are Stryker Corporation, Smith & Nephew plc, Vericel Corporation, B. Braun Melsungen AG, and Arthrex, Inc, among others.

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