Reports
Reports
The global next generation sequencing market size attained a value of USD 8.92 billion in 2022. The market is expected to grow at CAGR 13.83% during the forecast period of 2023-2031 to reach a value of about USD 29.19 billion by 2031. The market growth is driven by the increased government programmes and the increased funding for the large-scale genome projects.
Read more about this report - REQUEST FREE SAMPLE COPY IN PDF
Next generation sequencing (NGS) is used to identify the nucleotide order in a specific DNA sample. It makes the sequencing of DNA or RNA quicker and more affordable. Technology breakthroughs in sequencing techniques, rise in genome mapping initiatives, and an increase in drug discovery platforms requiring NGS technology are among the primary drivers for the market. The technique was formerly called “massively parallel sequencing” as it enables a sequence of multiple DNA strands at one time.
Modern sequencing techniques, like Roche 454 and Illumina sequencing, are included in next-generation sequencing. Comparing the classic Sanger's sequencing approach to next-generation sequencing, the latter is less expensive and provides higher throughput for DNA sequencing. NGS is widely used in the field of genetic disease research newborn sequencing metagenomics, precision medicines, biological drug discovery, animal and agricultural research, and oncology research and used for the identification of binding sites on transcriptional factors, non-coding RNA expression profiling, and re-sequencing of the target.
The application of NGS is also rising due to the increase in government programmes for large-scale genome sequencing projects and the introduction of cloud computing as a potential data management service. NGS tools are used in personalised medicine to identify gene expressions, assisting in the development of precision medicine based on the patient's characteristics.
The domains of medical diagnostics have seen dramatic changes because of the discovery of new biomarkers for various diseases, particularly cancer. The effectiveness of biomarkers in illness identification has also risen because of ongoing advancements in sequencing technologies and a deeper understanding of genetics.
Governments around the world are anticipated to make sizeable investments in genome sciences, which is likely to bolster the growth of the next generation sequencing market. Precise diagnosis and personalised medicine increase survival rates and reduce the financial burden on national health insurance programmes.
The market can be categorised on the basis of type, consumables, applications, end-user, and major regions.
Read more about this report - REQUEST FREE SAMPLE COPY IN PDF
Market Breakup by Type
Market Breakup by Consumables
Next Generation Sequencing Market Breakup by Applications
Market Breakup by End User
Market Breakup by Region
Read more about this report - REQUEST FREE SAMPLE COPY IN PDF
Global adoption of the newest NGS technologies has been significantly enhanced by the low cost of genome sequencing combined with the availability, effectiveness, and accuracy of NGS devices.
Some institutions and businesses lack the necessary infrastructure to conduct sequencing operations. Additionally, outsourcing the NGS project is a time and money-effective substitute for hiring personnel with specialised skill sets and establishing the infrastructure required to carry out NGS effectively in situations where only a small number of samples need to be sequenced.
As a result, the next generation sequencing market is seeing an increasing trend of corporations outsourcing sequencing to them at low costs. Some of the outsourcing organisations are BGI(China), Eurofins (Luxembourg), GENEWIZ (US), Macrogen (South Korea) PerkinElmer (US), QIAGEN (Netherlands), and Novogene (China). The main drivers of the growth of the NGS market include the rising NGS service offerings of businesses, the complexity of NGS procedures, and the use of cutting-edge NGS platforms by service providers.
The lack of funding and grants for research and academics in developing nations is restraining the adoption of NGS technologies. Despite the ongoing attempts by government and corporate organisations to offer funds for research around the world, many academic and research institutions struggle with budget restrictions when purchasing cutting-edge and expensive equipment and technology.
Many nations have engaged in their own national population genome mapping initiatives to better understand the relationship between heredity and disease. Government organisations are also sequencing millions of genomes for further advancements in science and to find new ways to diagnose and treat diseases including cancer, rare disorders, and other afflictions.
With initiatives like the United Kingdom's 100,000 Genomes Project and France's French Plan for Genomic Medicine 2025, the European Union is working to improve the region's large-scale genomic data. NGS informatics services have increased in the area because of such activities.
The global next generation sequencing market is dominated by North America. Numerous clinical laboratories that use NGS to deliver genetic testing services and the development of WGS in the region is anticipated to play a crucial role in the growth of the market in North America throughout the projected period. This can be attributed to the presence of significant R&D investment and the availability of a technologically sophisticated healthcare research framework.
The market in the Asia Pacific region is anticipated to expand quickly over the forecast period as a result of significant technological advancements made by China and Japan in the area of NGS technologies.
Additionally, the development of healthcare, R&D, and clinical development frameworks in emerging economies, like India and Australia, has positioned the region's NGS market to benefit from profitable growth opportunities.
Genomes, Transcriptomes, and Interactomes have been thoroughly analysed with the help of the variations and quick evolution of modern NGS platforms and high throughput data analysis tools, delivering biologically significant and clinically pertinent information. This large-scale study involves genomics, exomics, metagenomics, epigenomics, and transcriptomics for the development of the following aspects:
Additionally, NGS offers a strong platform for finding disease-related mutations, allowing for a more precise diagnosis of patient’s illnesses by giving detailed genome sequence data. This helps determine the treatment response and the mechanism of drug resistance in the case of antibiotics and chemotherapeutics, allowing for the selection of the most appropriate therapeutic intervention.
NGS is expected to develop safer vaccines and enter pre-vaccination genome-wide screening to generate personalised vaccinations to minimise the adverse events. Other than this pharmacogenomics, polypharmacology, and pharmacoepidemiology are the areas under the influence of NGS for providing immediate application benefits in healthcare research and development.
The oncology segment is expected to drive the next generation sequencing market as the use of cutting-edge technology is necessary to help oncologists better understand the biology of cancer and tumour cells. The application of NGS for DNA and RNA sequencing, epigenetics, and chromosomal abnormalities analysis accounts for more than three-fourth of the world's sequencing data. These applications adding further growth to the market.
NGS in cancer focuses on distinct gene sets. BCC Research predicts that as sequencing costs decrease and the utility of testing for just one gene (or a small number of genes) falls, whole-exome and whole-genome sequencing will gain popularity. In the long run, it is anticipated that most tumours will be fully sequenced, allowing doctors to treat patients with a thorough understanding of an individual’s genetic makeup.
NGS in cancer has made familial screening available to anyone at risk or relatives of cancer patients. Genetic testing among a larger population such as this could lower the mortality rate and overall costs of the disease. Relatives of cancer patients may be at greater risk of developing cancer. The primary driving force for this application is a decline in sequencing prices to the point where NGS diagnostics offer considerable cost-benefit ratios.
Menedelian Disorders, also known as rare disorders, are difficult to diagnose. To know the cause of the disorder, the patient needs to undergo expensive and invasive clinical procedures, which usually include serial molecular testing of one or few genes. BCC researchers studied the most common mendelian disorders in the states, which include cystic fibrosis and muscular dystrophy. With NGS up their sleeves, it is easier and quicker to diagnose mendelian disorders and cost-effective.
The main benefit of NGS is its high multiplexing, which allows it to cover a wide range of genes in a single test format, even those for which there are no available commercial molecular tests. The most common challenge mentioned by several organisations are demonstrating the clinical usefulness of such test formats to the medical community is one of the main difficulties in deploying NGS for this application.
Prenatal, infant, and preimplantation screening are the three main uses of NGS diagnostics in reproductive health. Reduced invasive procedures and early detection of foetal aneuploidy are the main clinical advantages of adopting NGS-based testing. NGS testing is mostly utilised today to screen pregnant women who are at a high risk of giving birth to children with chromosomal abnormalities. Whether the average-risk patient population will adopt NGS-based screening is a crucial question that will affect future market potential.
As the cost of the technology continues to decline, NGS holds out a lot of promise. Newborn screening comprises sequencing a newborn's genome and storing that data as a reference sequence for the duration of the child's life. The main factor influencing this use is the decrease in sequencing and related informatics costs because mass screening is largely cost-dependent. Given that it is anticipated that sequencing prices will continue to decrease, the outlook for this market application is positive.
A new application for NGS is preimplantation screening. The ability to raise in-vitro fertilisation's pregnancy success rates is a significant advantage. The key technological challenge is the inability to offer these tests at a competitive price compared to microarray methods and hence expand the use of NGS.
Apart from these NGS is also emerging in the applications of microbiology, infectious disease, and complex disorders (immune system, metabolic and mitochondrial, cardiovascular, and neurological disorders) and is also being integrated in clinical healthcare.
The report gives an in-depth analysis of the key players involved in the next generation sequencing market, sponsors manufacturing the drugs, and putting them through trials to get FDA approvals. The companies included in the market are as follows:
REPORT FEATURES | DETAILS |
---|---|
Base Year | 2022 |
Historical Period | 2016-2022 |
Forecast Period | 2023-2031 |
Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
|
Breakup by Type |
|
Breakup by Consumables |
|
Breakup by Application |
|
Breakup by End-User |
|
Breakup by Region |
|
Market Dynamics |
|
Supplier Landscape |
|
Companies Covered |
|
*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.
1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage – Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Global Next Generation Sequencing Market Overview
3.1 Global Next Generation Sequencing Market Historical Value (2016-2022)
3.2 Global Next Generation Sequencing Market Forecast Value (2023-2031)
4 Global Next Generation Sequencing Market Landscape
4.1 Global Next Generation Sequencing Developers Landscape
4.1.1 Analysis by Year of Establishment
4.1.2 Analysis by Company Size
4.1.3 Analysis by Region
4.2 Global Next Generation Sequencing Product Landscape
4.2.1 Analysis by Type
4.2.2 Analysis by Applications
4.2.3 Analysis by End Users
5 Global Next Generation Sequencing Market Dynamics
5.1 Market Drivers and Constraints
5.2 SWOT Analysis
5.3 Porter’s Five Forces Model
5.4 Key Demand Indicators
5.5 Key Price Indicators
5.6 Industry Events, Initiatives, and Trends
5.7 Value Chain Analysis
6 Global Next Generation Sequencing Market Segmentation
6.1 Global Next Generation Sequencing Market by Type
6.1.1 Market Overview
6.1.2 DNA Sequencing
6.1.2.1 Whole Genome Sequencing
6.1.2.2 Targeted Sequencing
6.1.2.3 Whole Exome Sequencing
6.1.2.4 Hybridization Capture
6.1.2.5 Amplicon Sequencing
6.1.2.6 Molecular Inversion Probes (MIPs)
6.1.3 RNA Sequencing
6.1.3.1 Whole Transcriptome Sequencing (WTS)
6.1.3.1.1 Targeted Gene Expression with RNA sequencing
6.1.3.1.2 Ribosomal RNA Depletion
6.1.3.2 Epigenomics
6.1.3.2.1 ChIP-Sequencing
6.1.3.2.2 Methyl-Sequencing
6.2 Global Next Generation Sequencing Market by Consumables
6.2.1 Market Overview
6.2.2 Sample Preparation
6.2.2.1 DNA Fragmentation
6.2.2.2 End Repair
6.2.2.3 A-Tailing
6.2.2.4 Size Selection
6.2.2.5 Library Preparation
6.2.2.6 Target Enrichment
6.2.2.7 Quality Control
6.2.3 Other Consumables
6.2.3.1 Platforms
6.2.3.2 HiSeq
6.2.3.3 MiSeq
6.2.3.4 Ion Torrent
6.2.3.5 SOLiD
6.2.3.6 Pacbio Rs II and Sequel System
6.2.3.7 Other Platforms
6.3 Global Next Generation Sequencing Market by Applications
6.3.1 Market Overview
6.3.2 Drug Discovery and Development
6.3.3 Biomarker Discovery
6.3.4 Biopharmaceutical Development
6.3.5 Vaccine Development
6.3.6 Pharmacogenomics
6.3.7 Poly pharmacology
6.3.8 Pharmacoepidemiology
6.4 Global Next Generation Sequencing Market by End User
6.4.1 Market Overview
6.4.2 Clinical Research
6.4.3 Academic Research
6.4.4 Pharmaceutical and Biotechnology Companies
6.4.5 Hospitals
6.4.6 Others
6.5 Global Next Generation Sequencing Market by Region
6.5.1 Market Overview
6.5.2 North America
6.5.3 Europe
6.5.4 Asia Pacific
6.5.5 Latin America
6.5.6 Middle East and Africa
7 North America Next Generation Sequencing Market
7.1 Market Share by Country
7.2 United States of America
7.3 Canada
8 Europe Next Generation Sequencing Market
8.1 Market Share by Country
8.2 United Kingdom
8.3 Germany
8.4 France
8.5 Italy
8.6 Others
9 Asia Pacific Next Generation Sequencing Market
9.1 Market Share by Country
9.2 China
9.3 Japan
9.4 India
9.5 ASEAN
9.6 Australia
9.7 Others
10 Latin America Next Generation Sequencing Market
10.1 Market Share by Country
10.2 Brazil
10.3 Argentina
10.4 Mexico
10.5 Others
11 Middle East and Africa Next Generation Sequencing Market
11.1 Market Share by Country
11.2 Saudi Arabia
11.3 United Arab Emirates
11.4 Nigeria
11.5 South Africa
11.6 Others
12 Patent Analysis
12.1 Analysis by Type of Patent
12.2 Analysis by Publication year
12.3 Analysis by Issuing Authority
12.4 Analysis by Patent Age
12.5 Analysis by CPC Analysis
12.6 Analysis by Patent Valuation
12.7 Analysis by Key Players
13 Grants Analysis
13.1 Analysis by year
13.2 Analysis by Amount Awarded
13.3 Analysis by Issuing Authority
13.4 Analysis by Grant Application
13.5 Analysis by Funding Institute
13.6 Analysis by NIH Departments
13.7 Analysis by Recipient Organization
14 Funding Analysis
14.1 Analysis by Funding Instances
14.2 Analysis by Type of Funding
14.3 Analysis by Funding Amount
14.4 Analysis by Leading Players
14.5 Analysis by Leading Investors
14.6 Analysis by Geography
15 Partnership and Collaborations Analysis
15.1 Analysis by Partnership Instances
15.2 Analysis by Type of Partnership
15.3 Analysis by Leading Players
15.4 Analysis by Geography
16 Regulatory Framework
16.1 Regulatory Overview
16.1.1 US FDA
16.1.2 EU EMA
16.1.3 INDIA CDSCO
16.1.4 JAPAN PMDA
16.1.5 Others
17 Supplier Landscape
17.1 Illumina Inc.
17.1.1 Financial Analysis
17.1.2 Financial Portfolio
17.1.3 Demographic Reach and Achievements
17.1.4 Mergers and Acquisitions
17.1.5 Certifications
17.2 F. Hoffmann-La Roche Ltd.
17.2.1 Financial Analysis
17.2.2 Financial Portfolio
17.2.3 Demographic Reach and Achievements
17.2.4 Mergers and Acquisitions
17.2.5 Certifications
17.3 Thermo Fisher Scientific, Inc.
17.3.1 Financial Analysis
17.3.2 Financial Portfolio
17.3.3 Demographic Reach and Achievements
17.3.4 Mergers and Acquisitions
17.3.5 Certifications
17.4 Bio-Rad Laboratories, Inc.
17.4.1 Financial Analysis
17.4.2 Financial Portfolio
17.4.3 Demographic Reach and Achievements
17.4.4 Mergers and Acquisitions
17.4.5 Certifications
17.5 PierianDX
17.5.1 Financial Analysis
17.5.2 Financial Portfolio
17.5.3 Demographic Reach and Achievements
17.5.4 Mergers and Acquisitions
17.5.5 Certifications
17.6 Genomatrix GmbH
17.6.1 Financial Analysis
17.6.2 Financial Portfolio
17.6.3 Demographic Reach and Achievements
17.6.4 Mergers and Acquisitions
17.6.5 Certifications
17.7 DNASTAR, Inc.
17.7.1 Financial Analysis
17.7.2 Financial Portfolio
17.7.3 Demographic Reach and Achievements
17.7.4 Mergers and Acquisitions
17.7.5 Certifications
17.8 Perkin Elmer, Inc,
17.8.1 Financial Analysis
17.8.2 Financial Portfolio
17.8.3 Demographic Reach and Achievements
17.8.4 Mergers and Acquisitions
17.8.5 Certifications
17.9 Eurofins GATC Biotech GmbH
17.9.1 Financial Analysis
17.9.2 Financial Portfolio
17.9.3 Demographic Reach and Achievements
17.9.4 Mergers and Acquisitions
17.9.5 Certifications
17.10 Agilent Technologies, Inc.
17.10.1 Financial Analysis
17.10.2 Financial Portfolio
17.10.3 Demographic Reach and Achievements
17.10.4 Mergers and Acquisitions
17.10.5 Certifications
17.11 Danaher Corp.
17.11.1 Financial Analysis
17.11.2 Financial Portfolio
17.11.3 Demographic Reach and Achievements
17.11.4 Mergers and Acquisitions
17.11.5 Certifications
17.12 BGI Genomics
17.12.1 Financial Analysis
17.12.2 Financial Portfolio
17.12.3 Demographic Reach and Achievements
17.12.4 Mergers and Acquisitions
17.12.5 Certifications
18 Global Next Generation Sequencing Market - Distribution Model (Additional Insight)
18.1 Overview
18.2 Potential Distributors
18.3 Key Parameters for Distribution Partner Assessment
19 Key Opinion Leaders (KOL) Insights (Additional Insight)
20 Company Competitiveness Analysis (Additional Insight)
20.1 Very Small Companies
20.2 Small Companies
20.3 Mid-Sized Companies
20.4 Large Companies
20.5 Very Large Companies
21 Payment Methods (Additional Insight)
21.1 Government Funded
21.2 Private Insurance
21.3 Out-of-Pocket
*Additional insights provided are customisable as per client requirements.
The global next generation sequencing market size attained a value of USD 8.92 billion in 2022.
The market is expected to grow at CAGR 13.83% during the forecast period of 2023-2031 to reach a value of about USD 29.19 billion by 2031.
The market growth is driven by the low cost of genome sequencing combined with the availability, effectiveness, and accuracy of NGS devices.
The major regions in the industry are North America, Latin America, the Middle East and Africa, Europe, and the Asia Pacific, with North America accounting for the largest share in the market.
The different types of next generation sequencing include DNA sequencing and RNA sequencing.
The consumables can be included into sample preparation and other consumables.
It finds wide applications in drug discovery and development, biomarker discovery, biopharmaceutical development, vaccine development, pharmacogenomics, poly pharmacology, and pharmacoepidemiology.
The end-users for the market include clinical research, academic research, hospitals, pharmaceutical and biotechnology companies, among others.
The major players in the industry are Illumina Inc., F. Hoffmann-La Roche Ltd., Thermo Fisher Scientific, Inc., Bio-Rad Laboratories, Inc., PierianDX, Genomatrix GmbH, DNASTAR, Inc., Perkin Elmer, Inc, Eurofins GATC Biotech GmbH, Agilent Technologies, Inc., Danaher Corp., and BGI Genomics.
A type of DNA sequencing technology, known as next-generation sequencing (NGS), employs parallel sequencing to identify the sequence of many tiny DNA fragments. The rate at which a genome can be sequenced has dramatically increased (while also becoming significantly less expensive) because to this "high-throughput" technology.
NGS performs a wide range of methods to address platforms like genome, transcriptome, and epigenome.
Mini Report
Single User License
Five User License
Corporate License
Any Question? Speak With An Analyst
View A Sample
Did You Miss Anything, Ask Now
Right People
We are technically excellent, strategic, practical, experienced and efficient; our analysts are hand-picked based on having the right attributes to work successfully and execute projects based on your expectations.
Right Methodology
We leverage our cutting-edge technology, our access to trusted databases, and our knowledge of the current models used in the market to deliver you research solutions that are tailored to your needs and put you ahead of the curve.
Right Price
We deliver in-depth and superior quality research in prices that are reasonable, unmatchable, and shows our understanding of your resource structure. We, additionally, offer attractive discounts on our upcoming reports.
Right Support
Our team of expert analysts are at your beck and call to deliver you optimum results that are customised to meet your precise needs within the specified timeframe and help you form a better understanding of the industry.