The global Alpha-1 Antitrypsin Deficiency (AATD) Treatment market is expected to grow at a CAGR of 9.50% during the period 2025-2034. The prevalence is nearly 0.025% in general population. Asia has comparatively less incidence of AATD as compared to Europe or North American population. North America and Europe are likely to be key markets.
Base Year
Historical Period
Forecast Period
Compound Annual Growth Rate
9.5%
Value in USD Million
2025-2034
Alpha-1 Antitrypsin Deficiency (AATD) Treatment Market Outlook
*this image is indicative*
Alpha-1 antitrypsin deficiency (AATD) is a genetic illness, and may cause severe lung or liver disease. Symptoms may include trouble breathing and jaundiced, or yellow, skin.
Complications of Alpha-1 antitrypsin deficiency (AATD) depend on the disease it causes. These may include: lungs [if lung disease is developed, complications may include emphysema or bronchiectasis (damage to airway walls in the lungs)], liver (if liver disease is causes, symptoms may include swelling of abdomen and legs, higher risk of infections, or developing liver scarring or cancer), skin (in rare cases, a skin disease called panniculitis may develop; the condition may cause painful red lumps on the skin; the lumps may break open and release liquid or pus).
Augmentation therapy is the only particular therapy for alpha-1 antitrypsin deficiency (AATD); during the therapy, preparations of alpha-1 antitrypsin protein isolated from pooled blood of healthy donors are administered by way of weekly intravenous infusion. This raises the blood levels of alpha-1 antitrypsin deficiency AATD to levels protective for the lung. Studies report that augmentation therapy helps preserve lung function and reduces the number and severity of lung infections. While there is no cure for alpha-1 antitrypsin deficiency (AATD), the lung diseases that it causes can be treated. Treatment includes bronchodilators (enable easier breathing by relaxing the muscles surrounding the airways; short-acting bronchodilators last about four to six hours and are used as required; long-acting bronchodilators last twelve hours or more and may be used every day), inhaled corticosteroid medications (help decrease inflammation of the airways, enabling easy breathing), antibiotics, flu and pneumococcal vaccines, and surgery and other treatments (in advanced cases of disease, surgical options may be considered, such as lung volume reduction surgery and bullectomy). Along with treatment and medication, lifestyle changes may also be recommended, including exercise, training in managing the condition, and nutritional and psychological counselling.
The EMR’s report titled “Alpha-1 Antitrypsin Deficiency (AATD) Treatment Market Report and Forecast 2025-2034” offers a detailed analysis of the market based on the following segments:
By product, the market is segmented into:
By route of administration, the market is classified into:
By application, the market is divided into:
By region, the market is segmented into:
The report presents a detailed analysis of the following key players in the global Alpha-1 Antitrypsin Deficiency (AATD) Treatment market, looking into their capacity, and latest developments like capacity expansions, plant turnarounds, and mergers and acquisitions:
The EMR report gives an in-depth insight into the industry by providing a SWOT analysis as well as an analysis of Porter’s Five Forces model.
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An increased chance of developing chronic obstructive pulmonary disease (COPD), liver disease, skin issues (panniculitis), and blood vessel inflammation is associated with alpha-1 antitrypsin deficiency (AATD), a hereditary condition (vasculitis).
Most people could live good life with normal life expectancies, work, enjoy sports, and exercise with the right care. Damage to the liver and lungs might have symptoms and problems that can be treated medically.
The market is projected to grow at a CAGR of 9.50% between 2025 and 2034.
The major drivers of the market include the growing number of strategic collaboration, research and development activities, rising number of genetic tests, blood tests, and biopsy tests, rising initiatives by public and private organisations, and an increase in the prescription for combination therapies.
Growing geriatric population and rising healthcare expenditure are the key industry trends propelling the market's growth.
The major regions in the industry are North America, Latin America, the Middle East and Africa, Europe, and the Asia Pacific.
The various products in the market are bronchodilators, oxygen therapy, augmentation therapy, and corticosteroids.
Based on route of administration, the market is classified into injection, oral, and inhalation.
The major applications of the market are speciality clinics, hospitals, and pharmacies.
Although there's no cure for AAT deficiency, but one can raise the amount of AAT protein in their blood, which protects the person against more lung damage. Doctors call this augmentation therapy.
The major players in the global Alpha-1 Antitrypsin Deficiency (AATD) treatment industry are Grifols, S.A., CSL Behring, Takeda Pharmaceutical Company Limited, Kamada Ltd, and Arrowhead Pharmaceuticals, Inc., among others.
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| REPORT FEATURES | DETAILS |
| Base Year | 2024 |
| Historical Period | 2018-2024 |
| Forecast Period | 2025-2034 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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| Breakup by Product |
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| Breakup by Route of Administration |
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| Breakup by Application |
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| Breakup by Region |
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| Market Dynamics |
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| Competitive Landscape |
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| Companies Covered |
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| Delivery Format | Delivered as an attached PDF and Excel through email, with an option of receiving an editable PPT, according to the purchase option. |
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