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Global Bioadhesive Microspheres Market: By Material: Natural Polymers, Synthetic Polymers; By Route of Drug Delivery: Oral, Nasal, Ocular, Colorectal, Others; By End Use; Regional Analysis; Historical Market and Forecast (2018-2028); Market Dynamics: SWOT Analysis; Competitive Landscape; Industry Events and Developments
Global Bioadhesive Microspheres Market Outlook
The global bioadhesive microspheres market is expected to grow at a CAGR of 8.5% during the period 2023-2028. North America and Europe are expected to be key markets.
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Global Market Likely to be Driven by Advancements in Drug Carrier Technologies and Increasing Applications of Bioadhesive Microspheres as Drug Carrier
The notion of controlled drug delivery has been conventionally used to achieve particular release rates or spatial targeting of active ingredients. Bioadhesion has been extensively researched over the last decade and applied to enhance the performance of drug delivery systems. Advancements in polymer science and drug carrier technologies have led to the development of novel drug carriers such as bioadhesive microspheres that have increased the use of “bioadhesion” in drug delivery. Bioadhesive microspheres display protracted residence time at site of application or absorption, and enable a close contact with underlying absorption surface, contributing to improved and/or better therapeutic performance of drugs. In recent years, bioadhesive microspheres have been advanced for buccal, oral, rectal, ocular, nasal and vaginal routes for systemic or local effects.
Mucoadhesive polymers have gained much interest among pharmaceutical scientists as a means of enhancing drug delivery by increasing residence time and contact time with mucous membranes.
Mucoadhesion refers to a state in which two components (one of biological origin), are held together for an extended duration of time through interfacial forces. Multiple polymers have exhibited bioadhesive characteristics been used in the development of different conventional and novel drug delivery systems. These carriers have been shown to enhance local therapeutic activity as well as increase the systemic availability of the drugs by increasing residence time at the site of application.
Bioadhesive polymers may be broadly classified into two categories - specific and nonspecific. According to their properties, specific bioadhesive polymers (such as lectins, and fimbrins) show the capability to adhere to particular chemical structures within the biological molecules; nonspecific bioadhesive polymers (such as polyacrylic acid [PAA] and cyanoacrylates) show capability to bind with the cell surfaces and the mucosal layer.
Key Bioadhesive Microspheres Expected to Boost Market Growth
The use of key bioadhesive microspheres is likely to stimulate growth of global bioadhesive microspheres market. Some important bioadhesive polymers used in drug delivery include:
Chitosan - A biodegradable, nontoxic polymer attained by deacetylation of the N-acetyl glucosamine units of chitin, usually by hydrolysis under alkali conditions at high temperature. It possesses very good bioadhesive properties; it is a biocompatible, pH-dependent cationic polymer, soluble in water up to pH 6.2. Chitosan (along with its derivatives) has been employed in the formulation of multiple mucoadhesive-controlled drug delivery systems.
Carbopol - High molecular weight polymers of acrylic acid cross-linked with allyl sucrose or allyl ethers of penta erythritol; employed as suspending agent or viscosity boosting agent, dry and wet binder, and rate regulating agent in tablets, enzyme inhibitor of intestinal protease in peptide containing dosage form, etc. Carbopol exhibits outstanding mucoadhesive properties in comparison with other polymers (such as cellulose derivatives and polyvinyl alcohol). Different mucoadhesive formulations carrying carbopol have been developed; these were found to show excellent mucoadhesive property and release the drug in a regulated fashion for a longer period of time.
Alginate - Alginates are random anionic, linear polymers comprising different ratios of glucuronic and manuronic acid units. Alginate has been employed in several biomedical applications, including drug delivery systems; these are biodegradable, biocompatible, and mucoadhesive. Calcium alginate matrix is generally used for drug delivery systems including gels, films, beads, microparticles, and sponges.
Sodium carboxymethyl cellulose (Na CMC) – A cost-effective, commercial, soluble, and polyanionic polysaccharide derivative of cellulose employed in medicine as an emulsifying agent in cosmetics and pharmaceuticals.
Hydroxypropyl methyl cellulose (HPMC) – A semisynthetic, inert, viscoelastic polymer employed as an ophthalmic lubricant, suspending agent, emulsifier, thickening agent, and controlled-delivery component in oral medicaments, is present in several commercial products. It is also known as hypermellose, and is a thermosenstive polymer the aqueous solution of which converts into gel when heated up to critical temperature. It displays good bioadhesive property owing to its capability to exhibit strong hydrogen bonding with the mucin present in the mucosal layer. HPMC as mucoadhesive polymer has bee employed in various films, tablets, and gel formulations.
Development of New Drug Delivery Systems Likely to Drive Market Growth
Companies are looking to develop novel drug delivery system of current drug molecule to maximize their impact in terms of therapeutic action and patient protection. Such developments are expected to boost growth of global bioadhesive microspheres market. Mucoadhesive polymers might offer an important tool to enhance the bioavailability of the active agent by improving residence time at the delivery site. The most extensively researched and accepted polymers for mucoadhesion are the hydrophilic, high molecular weight, anionic molecules such as carbomers. Focus has also been on novel second generation polymers such as thiolated polymers, lectins, and lecithins. Several potential mucoadhesive systems are under investigation, and may be introduced to the market in the near future.
Market Segmentation
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By material, the market is segmented into:
- Natural Polymers
- Synthetic Polymers (further broken down by type as given below)
- Biodegradable
- Non-biodegradable
By route of drug delivery, the market is divided into:
- Oral
- Nasal
- Ocular
- Colorectal
- Others
By end use, the market is divided into:
- Hospitals
- Clinics
- Academic and Research Institutes
- Pharmaceutical and Biotechnology Industries
- Others
By region, the market is classified into:
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East and Africa
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Key Industry Players in the Market
The report presents a detailed analysis of the following key players in the global bioadhesive microspheres market, looking into their capacity, and latest developments like capacity expansions, plant turnarounds, and mergers and acquisitions:
- Henkel AG & Co. KGaA
- Ashland Global Holdings Inc.
- Luminex Corporation
- Adhesives Research, Inc.
- ABK Biomedical Inc.
- Others
The EMR report gives an in-depth insight into the industry by providing a SWOT analysis as well as an analysis of Porter’s Five Forces model.
Key Highlights of the Report
| REPORT FEATURES | DETAILS |
|---|---|
| Base Year | 2022 |
| Historical Period | 2018-2022 |
| Forecast Period | 2023-2028 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
|
| Breakup by Material |
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| Breakup by Route of Drug Delivery |
|
| Breakup by End Use |
|
| Breakup by Region |
|
| Market Dynamics |
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| Competitive Landscape |
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| Companies Covered |
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| Report Price and Purchase Option | Explore our purchase options that are best suited to your resources and industry needs. |
| Delivery Format | Delivered as an attached PDF and Excel through email, with an option of receiving an editable PPT, according to the purchase option. |
*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.
1 Preface
2 Report Coverage – Key Segmentation and Scope
3 Report Description
3.1 Market Definition and Outlook
3.2 Properties and Applications
3.3 Market Analysis
3.4 Key Players
4 Key Assumptions
5 Executive Summary
5.1 Overview
5.2 Key Drivers
5.3 Key Developments
5.4 Competitive Structure
5.5 Key Industrial Trends
6 Market Snapshot
6.1 Global
6.2 Regional
7 Opportunities and Challenges in the Market
8 Global Bioadhesive Microspheres Market Analysis
8.1 Key Industry Highlights
8.2 Global Bioadhesive Microspheres Historical Market (2018-2022)
8.3 Global Bioadhesive Microspheres Market Forecast (2023-2028)
8.4 Global Bioadhesive Microspheres Market by Material
8.4.1 Natural Polymers
8.4.1.1 Historical Trend (2018-2022)
8.4.1.2 Forecast Trend (2023-2028)
8.4.2 Synthetic Polymers
8.4.2.1 Historical Trend (2018-2022)
8.4.2.2 Forecast Trend (2023-2028)
8.4.2.3 Breakup by Type
8.4.2.3.1 Biodegradable
8.4.2.3.2 Non-biodegradable
8.5 Global Bioadhesive Microspheres Market by Route of Drug Delivery
8.5.1 Oral
8.5.1.1 Historical Trend (2018-2022)
8.5.1.2 Forecast Trend (2023-2028)
8.5.2 Nasal
8.5.2.1 Historical Trend (2018-2022)
8.5.2.2 Forecast Trend (2023-2028)
8.5.3 Ocular
8.5.3.1 Historical Trend (2018-2022)
8.5.3.2 Forecast Trend (2023-2028)
8.5.4 Colorectal
8.5.4.1 Historical Trend (2018-2022)
8.5.4.2 Forecast Trend (2023-2028)
8.5.5 Others
8.6 Global Bioadhesive Microspheres Market by End Use
8.6.1 Hospitals
8.6.1.1 Historical Trend (2018-2022)
8.6.1.2 Forecast Trend (2023-2028)
8.6.2 Clinics
8.6.2.1 Historical Trend (2018-2022)
8.6.2.2 Forecast Trend (2023-2028)
8.6.3 Academic and Research Institutes
8.6.3.1 Historical Trend (2018-2022)
8.6.3.2 Forecast Trend (2023-2028)
8.6.4 Pharmaceutical and Biotechnology Industries
8.6.4.1 Historical Trend (2018-2022)
8.6.4.2 Forecast Trend (2023-2028)
8.6.5 Others
8.7 Global Bioadhesive Microspheres Market by Region
8.7.1 North America
8.7.1.1 Historical Trend (2018-2022)
8.7.1.2 Forecast Trend (2023-2028)
8.7.2 Europe
8.7.2.1 Historical Trend (2018-2022)
8.7.2.2 Forecast Trend (2023-2028)
8.7.3 Asia Pacific
8.7.3.1 Historical Trend (2018-2022)
8.7.3.2 Forecast Trend (2023-2028)
8.7.4 Latin America
8.7.4.1 Historical Trend (2018-2022)
8.7.4.2 Forecast Trend (2023-2028)
8.7.5 Middle East and Africa
8.7.5.1 Historical Trend (2018-2022)
8.7.5.2 Forecast Trend (2023-2028)
9 North America Bioadhesive Microspheres Market Analysis
9.1 United States of America
9.1.1 Historical Trend (2018-2022)
9.1.2 Forecast Trend (2023-2028)
9.2 Canada
9.2.1 Historical Trend (2018-2022)
9.2.2 Forecast Trend (2023-2028)
10 Europe Bioadhesive Microspheres Market Analysis
10.1 United Kingdom
10.1.1 Historical Trend (2018-2022)
10.1.2 Forecast Trend (2023-2028)
10.2 Germany
10.2.1 Historical Trend (2018-2022)
10.2.2 Forecast Trend (2023-2028)
10.3 France
10.3.1 Historical Trend (2018-2022)
10.3.2 Forecast Trend (2023-2028)
10.4 Italy
10.4.1 Historical Trend (2018-2022)
10.4.2 Forecast Trend (2023-2028)
10.5 Others
11 Asia Pacific Bioadhesive Microspheres Market Analysis
11.1 China
11.1.1 Historical Trend (2018-2022)
11.1.2 Forecast Trend (2023-2028)
11.2 Japan
11.2.1 Historical Trend (2018-2022)
11.2.2 Forecast Trend (2023-2028)
11.3 India
11.3.1 Historical Trend (2018-2022)
11.3.2 Forecast Trend (2023-2028)
11.4 ASEAN
11.4.1 Historical Trend (2018-2022)
11.4.2 Forecast Trend (2023-2028)
11.5 Australia
11.5.1 Historical Trend (2018-2022)
11.5.2 Forecast Trend (2023-2028)
11.6 Others
12 Latin America Bioadhesive Microspheres Market Analysis
12.1 Brazil
12.1.1 Historical Trend (2018-2022)
12.1.2 Forecast Trend (2023-2028)
12.2 Argentina
12.2.1 Historical Trend (2018-2022)
12.2.2 Forecast Trend (2023-2028)
12.3 Mexico
12.3.1 Historical Trend (2018-2022)
12.3.2 Forecast Trend (2023-2028)
12.4 Others
13 Middle East and Africa Bioadhesive Microspheres Market Analysis
13.1 Saudi Arabia
13.1.1 Historical Trend (2018-2022)
13.1.2 Forecast Trend (2023-2028)
13.2 United Arab Emirates
13.2.1 Historical Trend (2018-2022)
13.2.2 Forecast Trend (2023-2028)
13.3 Nigeria
13.3.1 Historical Trend (2018-2022)
13.3.2 Forecast Trend (2023-2028)
13.4 South Africa
13.4.1 Historical Trend (2018-2022)
13.4.2 Forecast Trend (2023-2028)
13.5 Others
14 Market Dynamics
14.1 SWOT Analysis
14.1.1 Strengths
14.1.2 Weaknesses
14.1.3 Opportunities
14.1.4 Threats
14.2 Porter’s Five Forces Analysis
14.2.1 Supplier’s Power
14.2.2 Buyer’s Power
14.2.3 Threat of New Entrants
14.2.4 Degree of Rivalry
14.2.5 Threat of Substitutes
14.3 Key Indicators for Demand
14.4 Key Indicators for Price
15 Competitive Landscape
15.1 Market Structure
15.2 Company Profiles
15.2.1 Henkel AG & Co. KGaA
15.2.1.1 Company Overview
15.2.1.2 Product Portfolio
15.2.1.3 Demographic Reach and Achievements
15.2.1.4 Certifications
15.2.2 Ashland Global Holdings Inc.
15.2.2.1 Company Overview
15.2.2.2 Product Portfolio
15.2.2.3 Demographic Reach and Achievements
15.2.2.4 Certifications
15.2.3 Luminex Corporation
15.2.3.1 Company Overview
15.2.3.2 Product Portfolio
15.2.3.3 Demographic Reach and Achievements
15.2.3.4 Certifications
15.2.4 Adhesives Research, Inc.
15.2.4.1 Company Overview
15.2.4.2 Product Portfolio
15.2.4.3 Demographic Reach and Achievements
15.2.4.4 Certifications
15.2.5 ABK Biomedical Inc.
15.2.5.1 Company Overview
15.2.5.2 Product Portfolio
15.2.5.3 Demographic Reach and Achievements
15.2.5.4 Certifications
15.2.6 Others
16 Key Trends and Developments in the Market
List of Key Figures and Tables
1. Global Bioadhesive Microspheres Market: Key Industry Highlights, 2018 and 2028
2. Global Bioadhesive Microspheres Historical Market: Breakup by Material (USD Million), 2018-2022
3. Global Bioadhesive Microspheres Market Forecast: Breakup by Material (USD Million), 2023-2028
4. Global Bioadhesive Microspheres Historical Market: Breakup by Route of Drug Delivery (USD Million), 2018-2022
5. Global Bioadhesive Microspheres Market Forecast: Breakup by Route of Drug Delivery (USD Million), 2023-2028
6. Global Bioadhesive Microspheres Historical Market: Breakup by End Use (USD Million), 2018-2022
7. Global Bioadhesive Microspheres Market Forecast: Breakup by End Use (USD Million), 2023-2028
8. Global Bioadhesive Microspheres Historical Market: Breakup by Region (USD Million), 2018-2022
9. Global Bioadhesive Microspheres Market Forecast: Breakup by Region (USD Million), 2023-2028
10. North America Bioadhesive Microspheres Historical Market: Breakup by Country (USD Million), 2018-2022
11. North America Bioadhesive Microspheres Market Forecast: Breakup by Country (USD Million), 2023-2028
12. Europe Bioadhesive Microspheres Historical Market: Breakup by Country (USD Million), 2018-2022
13. Europe Bioadhesive Microspheres Market Forecast: Breakup by Country (USD Million), 2023-2028
14. Asia Pacific Bioadhesive Microspheres Historical Market: Breakup by Country (USD Million), 2018-2022
15. Asia Pacific Bioadhesive Microspheres Market Forecast: Breakup by Country (USD Million), 2023-2028
16. Latin America Bioadhesive Microspheres Historical Market: Breakup by Country (USD Million), 2018-2022
17. Latin America Bioadhesive Microspheres Market Forecast: Breakup by Country (USD Million), 2023-2028
18. Middle East and Africa Bioadhesive Microspheres Historical Market: Breakup by Country (USD Million), 2018-2022
19. Middle East and Africa Bioadhesive Microspheres Market Forecast: Breakup by Country (USD Million), 2023-2028
20. Global Bioadhesive Microspheres Market Structure
Key Questions Answered in the Report
The global bioadhesive microspheres market is projected to grow at a CAGR of 8.5% between 2023 and 2028.
The major drivers of the market include the development of new drug delivery systems, growing usage of microspheres in clinical research, growing investments in research studies, and increasing prevalence of chronic disease and cancer.
Advancements in drug carrier technologies and increasing applications of bioadhesive microspheres as drug carrier are the key industry trends propelling the market growth.
The major regions in the industry are North America, Latin America, the Middle East and Africa, Europe, and the Asia Pacific.
Based on material, the market is segmented into natural polymers and synthetic polymers. Synthetic Polymers are further broken down into biodegradable and non-biodegradable.
The several routes of drug delivery are oral, nasal, ocular, and colorectal, among others.
The end-uses of the market are hospitals, clinics, academic and research institutes, pharmaceutical and biotechnology industries, among others.
The major players in the industry include Henkel AG & Co. KGaA, Ashland Global Holdings Inc., Luminex Corporation, Adhesives Research, Inc., and ABK Biomedical Inc., among others.
Analyst Review
The global bioadhesive microspheres market was driven by the advancements in drug carrier technologies in the historical period. Aided by the development of new drug delivery systems and increasing applications of bioadhesive microspheres as drug carrier, the market is expected to grow at a CAGR of 8.5% in the forecast period of 2023-2028.
EMR's meticulous research methodology delves deep into the market, covering the macro and micro aspects of the industry. Based on material, the market is segmented into natural polymers and synthetic polymers. Synthetic Polymers are further broken down into biodegradable and non-biodegradable. The several routes of drug delivery are oral, nasal, ocular, and colorectal, among others. The end-uses of the market are hospitals, clinics, academic and research institutes, pharmaceutical and biotechnology industries, among others. The major regional markets for bioadhesive microspheres are North America, Europe, the Asia Pacific, Latin America, the Middle East and Africa. The major players in the industry are Henkel AG & Co. KGaA, Ashland Global Holdings Inc., Luminex Corporation, Adhesives Research, Inc., and ABK Biomedical Inc., among others.
EMR's research methodology uses a combination of cutting-edge analytical tools and the expertise of their highly accomplished team, thus, providing their customers with market insights that are accurate, actionable and help them remain ahead of their competition.
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