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Global Cloning and Mutagenesis Market Size, Share, Growth: By Product: Cloning Kits, Others; By Technique: Topo PCR Cloning, Blunt End Cloning, Seamless Cloning, Site-Directed Mutagenesis; By End User: Biotechnology Companies, Academic and Research Institute, Others; Regional Analysis; Supplier Landscape; 2024-2032
Global Cloning and Mutagenesis Market Size
The global cloning and mutagenesis market is expected to grow at a CAGR of 17% during the forecast period of 2024-2032, driven by increased investment in genetic research, growing R&D activities, and the growing demand for personalized medicine.
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Global Cloning and Mutagenesis Market Outlook
- The rising prevalence of genetic disorders and chronic diseases is poised to augment the market demand in the forecast period.
- One of the major market trends is the rising integration of automation and high-throughput screening in cloning and mutagenesis processes that enhance the efficiency and accuracy of genetic manipulation experiments.
- The market share is impacted by the growing demand for personalized medicine, advancement in gene editing technologies, and increased investment in R&D activities.
Global Cloning and Mutagenesis Market Overview
Cloning refers to the creation of duplicates of organisms either artificially, or naturally, with nearly identical DNA coding. Mutagenesis is a method of changing the genetic information of an organism encoded into the DNA. The market growth for cloning and mutagenesis is driven by its rising use in finding new discoveries for therapeutics, vaccine development, and other emerging synthetic biology applications. Furthermore, the increasing research activities to develop next-generation cloning technology for creating custom vectors for various applications are likely to shape the market landscape.
The cloning and mutagenesis market is projected to witness substantial growth during the forecast period on account of the surging popularity of reproductive cloning. The rising penetration of personalized medications along with rising disease burden is further expected to boost the market demand across the globe. In addition, the growing investment in the research of treatment for genetic diseases is boosting the market share. The increasing efforts by governments such as providing funds for medical research coupled with the rapid growth of the biotechnology sector are encouraging market expansion.
Global Cloning and Mutagenesis Market Growth Drivers
Rising Prevalence of Genetic and Chronic Diseases to Affect the Market Landscape Significantly
The prevalence of genetic disorders fuels the demand for advanced genetic research to develop effective treatments, in which cloning, and mutagenesis techniques play a critical role in creating disease models and exploring gene therapy options. Cloning and mutagenesis tools also help to understand disease mechanisms and discover novel drugs for various chronic diseases.
With the growing prevalence of various genetic and chronic diseases, cloning of genes is extensively used in the detection of such conditions and in their treatment through methods like gene therapy. Hence, the rising cases of sickle cell anemia and leukemia, among others, are estimated to drive market growth in coming years.
Integration of Automation and High-Throughput Screening Set to Fuel Cloning and Mutagenesis Market Demand
The market is witnessing an increased integration of automation and high-throughput screening in cloning and mutagenesis processes that are shaping the market landscape. For instance, Beckman Coulter Life Sciences' Echo 525 Acoustic Liquid Handler automates the transfer of low-volume reagents for biochemical and genomic samples, enabling assay miniaturization and optimizing the efficiency of experiments. Moreover, Beacon Select, developed by Berkeley Lights, Inc. is a single cell optofluidic system that allows researchers to clone, culture, assay, as well as select top clones on a single platform in a single run. Such technological advancements are likely to enhance the speed, accuracy, and scalability of genetic manipulation experiments and are anticipated to be a significant growth driver of the market.
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Global Cloning and Mutagenesis Market Trends
The market is witnessing several trends and developments to improve the current global scenario. Some of the notable trends are as follows:
| Key Trends | Impact |
| Advancements in Gene Editing Technologies | One of the major market trends is the rising development and adoption of gene editing technologies such as CRISPR-Cas9 which has significantly improved the efficiency and precision of cloning and mutagenesis processes. These tools facilitate more accurate genetic modifications for various applications in research, medicine, and agriculture. Such advancements in gene editing technologies are expected to propel market growth. |
| Increased Investments in R&D | The market is experiencing a growing investment in R&D activities by pharmaceutical and biotechnology companies with the aim to develop and commercialize new drugs. In addition, universities and research institutions are heavily investing in genetic research, which is likely to augment the cloning and mutagenesis market demand in the coming years. |
| Growing Demand for Personalized Medicine | The market benefits from the rising demand for personalized medicine, which depends on genetic modifications to develop targeted therapies. For instance, CAR-T cell therapies utilize genetically modified T-cells of the patient to target and destroy cancer cells. |
| Expanding Applications | Increased application of cloning and mutagenesis technologies in the industrial biotechnology sector to optimize production processes is poised to fuel market demand. Manufacturers are using cloning and mutagenesis tools to produce enzymes, biofuels, genetically engineered microorganisms, and other bioproducts, which is anticipated to aid the market expansion. |
Global Cloning and Mutagenesis Segmentation
Market Breakup by Product
- Cloning Kits
- Others
Market Breakup by Technique
- Topo PCR Cloning
- Blunt End Cloning
- Seamless Cloning
- Site-Directed Mutagenesis
Market Breakup by End User
- Biotechnology Companies
- Academic and Research Institute
- Others
Market Breakup by Region
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East and Africa
Global Cloning and Mutagenesis Market Share
Market Segmentation Based on Technique is Anticipated to Witness Substantial Growth
Based on the techniques, the market is segmented into Topo PCR cloning, blunt end cloning, seamless cloning, and site-directed mutagenesis. In TOPO PCR cloning, topoisomerase enzymes are used to ligate the PCR products directly into vectors, eliminating the need for restriction enzymes or ligase. It is widely used for cloning PCR products for sequencing or for creating recombinant DNA for protein expression. Since the TOPO PCR cloning technique offers a rapid and efficient cloning process and doesn't require any additional restriction enzyme digestion and ligation step, it is expected to drive the demand of the market segment. On the other hand, blunt-end cloning is used for the construction of plasmid libraries and general molecular cloning applications.
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Global Cloning and Mutagenesis Market Analysis by Region
Based on the region, the market covers North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. North America holds a significant share of the market and is expected to register robust growth during the forecast period. This is on account of the huge investments in research and development in the medical field, coupled with the well-developed healthcare industry in the region.
Rising investments in biotechnology companies and the presence of market key players like Thermo Fisher Scientific Inc. and Codex DNA, Inc., among others, are expected to elevate the cloning and mutagenesis market value. Moreover, the surging investment in the development of stem cell and cancer cell studies is further anticipated to bolster the market growth in North America.
Meanwhile, the Asia Pacific region is expected to witness considerable market growth due to the rapidly growing healthcare industry and increasing investments in biotechnology.
Leading Players in the Global Cloning and Mutagenesis Market
The key features of the market report comprise strategic initiatives by the leading players including mergers and collaborations and new product launches. The major companies in the market are as follows:
Thermo Fisher Scientific Inc.
Thermo Fisher Scientific Inc. has a strong market presence and is actively working towards expanding its product portfolio to address various research needs. It offers a range of cloning kits, enzymes, and reagents, such as TOPO cloning kits, GeneArt Seamless Cloning kits, and Gateway cloning systems.
Takara Bio Inc.
Headquartered in Japan, Takara Bio Inc. develops and distributes life science reagents under the Takara®, Clontech®, and Cellartis® brands. It offers high-quality reagents and kits such as PrimeSTAR high-fidelity DNA polymerases and significantly contributes to the cloning and mutagenesis market growth.
Agilent Technologies, Inc.
California-based Agilent Technologies, Inc. is known for innovative solutions for cloning and mutagenesis. One of its key products includes QuikChange site-directed mutagenesis kits that are reported to expedite and simplify site-directed mutagenesis studies.
TransGen Biotech Co., LTD.
TransGen Biotech Co., LTD is a leading biotechnology company that manufactures over 200 molecular and cellular biology reagents. It holds a major market share by providing cost-effective and high-quality products including mutagenesis kits, cloning vectors, and PCR cloning kits.
Other key players in the market include Merck KGaA, Bio-Rad Laboratories, Inc., Promega Corporation, GenScript, Genes2Me, and New England Biolabs.
Key Highlights of the Report
| REPORT FEATURES | DETAILS |
| Base Year | 2023 |
| Historical Period | 2017-2023 |
| Forecast Period | 2024-2032 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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| Breakup by Product |
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| Breakup by Technique |
|
| Breakup by End User |
|
| Breakup by Region |
|
| Market Dynamics |
|
| Supplier Landscape |
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| Companies Covered |
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Key Questions Answered in the Global Cloning and Mutagenesis Market Report
- What was the global cloning and mutagenesis market value in 2023?
- What is the global cloning and mutagenesis market forecast outlook for 2024-2032?
- What are the regional markets covered in the EMR report?
- What is market segmentation based on product?
- What is the market breakup based on technique?
- Who are the major end users in the market?
- What are the major factors aiding the global cloning and mutagenesis market demand?
- How has the market performed so far and how is it anticipated to perform in the coming years?
- What are the major drivers, opportunities, and restraints?
- Which regional market is expected to lead the market share in the forecast period?
- Which country is expected to experience expedited growth during the forecast period?
- How does the prevalence and incidence of genetic disorders affect the market landscape?
- What are the major global cloning and mutagenesis market trends?
- What product will dominate the market share?
- Which technique is expected to have a high market value in the coming years?
- Which end user is projected to contribute to the highest market growth?
- Who are the key players involved in the cloning and mutagenesis market?
- What are the current unmet needs and challenges in the market?
- How are partnerships, collaborations, mergers and acquisitions among the key market players shaping the market dynamics?
Cloning and Mutagenesis Market Report Snapshots
Cloning and Mutagenesis Market Size
Cloning and Mutagenesis Market Growth
Cloning and Mutagenesis Market Trends
Cloning and Mutagenesis Market Share
Cloning and Mutagenesis Market Regional Analysis
Cloning and Mutagenesis Companies
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.
1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage – Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Global Cloning and Mutagenesis Market Overview
3.1 Global Cloning and Mutagenesis Market Historical Value (2017-2023)
3.2 Global Cloning and Mutagenesis Market Forecast Value (2024-2032)
4 Vendor Positioning Analysis
4.1 Key Vendors
4.2 Prospective Leaders
4.3 Niche Leaders
4.4 Disruptors
5 Global Cloning and Mutagenesis Market Landscape*
5.1 Global Cloning and Mutagenesis: Developers Landscape
5.1.1 Analysis by Year of Establishment
5.1.2 Analysis by Company Size
5.1.3 Analysis by Region
5.2 Global Cloning and Mutagenesis: Product Landscape
5.2.1 Analysis by Product
5.2.2 Analysis by Technology
6 Global Cloning and Mutagenesis Market Dynamics
6.1 Market Drivers and Constraints
6.2 SWOT Analysis
6.2.1 Strengths
6.2.2 Weaknesses
6.2.3 Opportunities
6.2.4 Threats
6.3 PESTEL Analysis
6.3.1 Political
6.3.2 Economic
6.3.3 Social
6.3.4 Technological
6.3.5 Legal
6.3.6 Environment
6.4 Porter’s Five Forces Model
6.4.1 Bargaining Power of Suppliers
6.4.2 Bargaining Power of Buyers
6.4.3 Threat of New Entrants
6.4.4 Threat of Substitutes
6.4.5 Degree of Rivalry
6.5 Key Demand Indicators
6.6 Key Price Indicators
6.7 Industry Events, Initiatives, and Trends
6.8 Value Chain Analysis
7 Global Cloning and Mutagenesis Market Segmentation (2017-2032)
7.1 Global Cloning and Mutagenesis Market (2017-2032) by Product
7.1.1 Market Overview
7.1.2 Cloning Kits
7.1.3 Others
7.2 Global Cloning and Mutagenesis Market (2017-2032) by Technique
7.2.1 Market Overview
7.2.2 Topo PCR Cloning
7.2.3 Blunt End Cloning
7.2.4 Seamless Cloning
7.2.5 Site-Directed Mutagenesis
7.3 Global Cloning and Mutagenesis Market (2017-2032) by End User
7.3.1 Market Overview
7.3.2 Biotechnology Companies
7.3.3 Academic and Research Institute
7.3.4 Others
7.4 Global Cloning and Mutagenesis Market (2017-2032) by Region
7.4.1 Market Overview
7.4.2 North America
7.4.3 Europe
7.4.4 Asia Pacific
7.4.5 Latin America
7.4.6 Middle East and Africa
8 North America Cloning and Mutagenesis Market (2017-2032)
8.1 North America Cloning and Mutagenesis Market (2017-2032) by Product
8.1.1 Market Overview
8.1.2 Cloning Kits
8.1.3 Others
8.2 North America Cloning and Mutagenesis Market (2017-2032) by Technique
8.2.1 Market Overview
8.2.2 Topo PCR Cloning
8.2.3 Blunt End Cloning
8.2.4 Seamless Cloning
8.2.5 Site-Directed Mutagenesis
8.3 North America Cloning and Mutagenesis Market (2017-2032) by End User
8.3.1 Market Overview
8.3.2 Biotechnology Companies
8.3.3 Academic and Research Institute
8.3.4 Others
8.4 North America Cloning and Mutagenesis Market (2017-2032) by Country
8.4.1 United States of America
8.4.2 Canada
9 Europe Cloning and Mutagenesis Market (2017-2032)
9.1 Europe Cloning and Mutagenesis Market (2017-2032) by Product
9.1.1 Market Overview
9.1.2 Cloning Kits
9.1.3 Others
9.2 Europe Cloning and Mutagenesis Market (2017-2032) by Technique
9.2.1 Market Overview
9.2.2 Topo PCR Cloning
9.2.3 Blunt End Cloning
9.2.4 Seamless Cloning
9.2.5 Site-Directed Mutagenesis
9.3 Europe Cloning and Mutagenesis Market (2017-2032) by End User
9.3.1 Market Overview
9.3.2 Biotechnology Companies
9.3.3 Academic and Research Institute
9.3.4 Others
9.4 Europe Cloning and Mutagenesis Market (2017-2032) by Country
9.4.1 United Kingdom
9.4.2 Germany
9.4.3 France
9.4.4 Italy
9.4.5 Others
10 Asia Pacific Cloning and Mutagenesis Market (2017-2032)
10.1 Asia Pacific Cloning and Mutagenesis Market (2017-2032) by Product
10.1.1 Market Overview
10.1.2 Cloning Kits
10.1.3 Others
10.2 Asia Pacific Cloning and Mutagenesis Market (2017-2032) by Technique
10.2.1 Market Overview
10.2.2 Topo PCR Cloning
10.2.3 Blunt End Cloning
10.2.4 Seamless Cloning
10.2.5 Site-Directed Mutagenesis
10.3 Asia Pacific Cloning and Mutagenesis Market (2017-2032) by End User
10.3.1 Market Overview
10.3.2 Biotechnology Companies
10.3.3 Academic and Research Institute
10.3.4 Others
10.4 Asia Pacific Cloning and Mutagenesis Market (2017-2032) by Country
10.4.1 China
10.4.2 Japan
10.4.3 India
10.4.4 ASEAN
10.4.5 Australia
10.4.6 Others
11 Latin America Cloning and Mutagenesis Market (2017-2032)
11.1 Latin America Cloning and Mutagenesis Market (2017-2032) by Product
11.1.1 Market Overview
11.1.2 Cloning Kits
11.1.3 Others
11.2 Latin America Cloning and Mutagenesis Market (2017-2032) by Technique
11.2.1 Market Overview
11.2.2 Topo PCR Cloning
11.2.3 Blunt End Cloning
11.2.4 Seamless Cloning
11.2.5 Site-Directed Mutagenesis
11.3 Latin America Cloning and Mutagenesis Market (2017-2032) by End User
11.3.1 Market Overview
11.3.2 Biotechnology Companies
11.3.3 Academic and Research Institute
11.3.4 Others
11.4 Latin America Cloning and Mutagenesis Market (2017-2032) by Country
11.4.1 Brazil
11.4.2 Argentina
11.4.3 Mexico
11.4.4 Others
12 Middle East and Africa Cloning and Mutagenesis Market (2017-2032)
12.1 Middle East and Africa Cloning and Mutagenesis Market (2017-2032) by Product
12.1.1 Market Overview
12.1.2 Cloning Kits
12.1.3 Others
12.2 Middle East and Africa Cloning and Mutagenesis Market (2017-2032) by Technique
12.2.1 Market Overview
12.2.2 Topo PCR Cloning
12.2.3 Blunt End Cloning
12.2.4 Seamless Cloning
12.2.5 Site-Directed Mutagenesis
12.3 Middle East and Africa Cloning and Mutagenesis Market (2017-2032) by End User
12.3.1 Market Overview
12.3.2 Biotechnology Companies
12.3.3 Academic and Research Institute
12.3.4 Others
12.4 Middle East and Africa Cloning and Mutagenesis Market (2017-2032) by Country
12.4.1 Saudi Arabia
12.4.2 United Arab Emirates
12.4.3 Nigeria
12.4.4 South Africa
12.4.5 Others
13 Regulatory Framework
13.1 Regulatory Overview
13.2 US FDA
13.3 EU EMA
13.4 INDIA CDSCO
13.5 JAPAN PMDA
13.6 Others
14 Strategic Initiatives
14.1 Analysis by Partnership Instances
14.2 Analysis by Type of Partnership and Collaborations
14.3 Analysis by Joint Ventures
14.4 Analysis by Leading Players
14.5 Analysis by Geography
15 Supplier Landscape
15.1 Market Share Analysis, By Region (Top 5 Companies)
15.1.1 Market Share Analysis: Global
15.1.2 Market Share Analysis: North America
15.1.3 Market Share Analysis: Europe
15.1.4 Market Share Analysis: Asia-Pacific
15.1.5 Market Share Analysis: Others
15.2 Thermo Fisher Scientific Inc.
15.2.1 Financial Analysis
15.2.2 Product Portfolio
15.2.3 Demographic Reach and Achievements
15.2.4 Mergers and Acquisitions
15.2.5 Certifications
15.3 Takara Bio Inc.
15.3.1 Financial Analysis
15.3.2 Product Portfolio
15.3.3 Demographic Reach and Achievements
15.3.4 Mergers and Acquisitions
15.3.5 Certifications
15.4 Agilent Technologies, Inc.
15.4.1 Financial Analysis
15.4.2 Product Portfolio
15.4.3 Demographic Reach and Achievements
15.4.4 Mergers and Acquisitions
15.4.5 Certifications
15.5 TransGen Biotech Co., LTD.
15.5.1 Financial Analysis
15.5.2 Product Portfolio
15.5.3 Demographic Reach and Achievements
15.5.4 Mergers and Acquisitions
15.5.5 Certifications
15.6 Merck KGaA
15.6.1 Financial Analysis
15.6.2 Product Portfolio
15.6.3 Demographic Reach and Achievements
15.6.4 Mergers and Acquisitions
15.6.5 Certifications
15.7 Bio-Rad Laboratories, Inc.
15.7.1 Financial Analysis
15.7.2 Product Portfolio
15.7.3 Demographic Reach and Achievements
15.7.4 Mergers and Acquisitions
15.7.5 Certifications
15.8 Promega Corporation
15.8.1 Financial Analysis
15.8.2 Product Portfolio
15.8.3 Demographic Reach and Achievements
15.8.4 Mergers and Acquisitions
15.8.5 Certifications
15.9 GenScript
15.9.1 Financial Analysis
15.9.2 Product Portfolio
15.9.3 Demographic Reach and Achievements
15.9.4 Mergers and Acquisitions
15.9.5 Certifications
15.10 Genes2Me
15.10.1 Financial Analysis
15.10.2 Product Portfolio
15.10.3 Demographic Reach and Achievements
15.10.4 Mergers and Acquisitions
15.10.5 Certifications
15.11 New England Biolabs
15.11.1 Financial Analysis
15.11.2 Product Portfolio
15.11.3 Demographic Reach and Achievements
15.11.4 Mergers and Acquisitions
15.11.5 Certifications
16 Global Cloning and Mutagenesis Market – Distribution Model (Additional Insight)
16.1 Overview
16.2 Potential Distributors
16.3 Key Parameters for Distribution Partner Assessment
17 Key Opinion Leaders (KOL) Insights (Additional Insight)
*Additional insights provided are customisable as per client requirements.
* The coverage of the Market Landscape section depends on the data availability and may cover a minimum of 80% of the total market. The EMR team strives to make this section as comprehensive as possible.
**The supplier list is not exhaustive. Moreover, we can provide analysis of companies as per custom requests.
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