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Report Overview

Mesothelioma is a rare, aggressive cancer affecting the lining of the lungs or other organs, primarily associated with asbestos exposure. According to the World Health Organization, mesothelioma causes more than 30,000 deaths globally each year. According to Mesothelioma epidemiology forecasts by Expert Market Research, disease burden remains an important concern, particularly in populations with historical asbestos exposure.

2025

Base Year

2019-2025

Historical Period

2026-2035

Forecast Period

Mesothelioma – Number of Cases by Year

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Mesothelioma Epidemiology Forecast Report Coverage

Expert Market Research's “Mesothelioma Epidemiology Forecast Report 2026-2035” offers comprehensive information on the prevalence and demographics of Mesothelioma. It projects the future incidence and prevalence rates of Mesothelioma cases across various populations. The study covers age, gender, and type as major determinants of the Mesothelioma population. The report highlights patterns in the prevalence of Mesothelioma over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of mesothelioma in the 8 major markets.

Regions Covered

  • United States
  • Germany
  • France
  • Italy
  • Spain
  • United Kingdom
  • Japan
  • India

Mesothelioma Understanding: Disease Overview

Mesothelioma is a rare and aggressive cancer that develops in the mesothelium, the thin tissue lining surrounding certain internal organs. It most commonly affects the pleura surrounding the lungs but can also develop in the peritoneum, pericardium, or tunica vaginalis. The disease is primarily associated with asbestos exposure, which can cause cellular damage and malignant transformation after a prolonged latency period. Major types include pleural and peritoneal mesothelioma, with pleural disease accounting for most cases. Occupational exposure remains an important risk factor, particularly among older adults with a history of asbestos contact. Asbestos-related malignancy is a relevant term for this disease.

Key Report Insights

Parameter

Insight

Largest Patient Pool

United States

Fastest Growing Country

India

High-Risk Population

Older adults and individuals with occupational or environmental asbestos exposure.

Key Diagnostic Method

Imaging, followed by tissue biopsy and histopathological examination; immunohistochemistry may help confirm the diagnosis.

Major Risk Factor

Asbestos exposure, including occupational exposure and exposure from contaminated environments.

Major gap in the market

Delayed diagnosis, limited early-detection options, and the need for more effective treatments, particularly for advanced disease.

Mesothelioma Epidemiology Perspective

The mesothelioma epidemiology division offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for the mesothelioma epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for mesothelioma and their trends. The data is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.

Epidemiology Segment

Key Insights

Diagnosed Prevalent Cases of the Disease

According to the American Cancer Society, approximately 3,000 new mesothelioma cases are diagnosed annually in the United States. The Centers for Disease Control and Prevention reported 2,669 US cases in 2022.

Gender-Specific Cases of the Disease

According to the Centers for Disease Control and Prevention and US Cancer Statistics, the 2024 US age-adjusted death rate was 0.8 per 100,000 men and 0.2 per 100,000 women, reflecting a higher mortality burden among men.

Age-Specific Cases of the Disease

As per the American Cancer Society, the average age at diagnosis of pleural mesothelioma is approximately 70 years. According to the Centers for Disease Control and Prevention and US Cancer Statistics (2026), adults aged 85 years and older had the highest crude death rate, at 7.2 per 100,000, in 2024.

Ethnicity-Wise Cases of the Disease

According to the Centers for Disease Control and Prevention and US Cancer Statistics, Asian and Pacific Islander populations had the lowest age-adjusted mesothelioma death rate in the United States in 2024, at 0.2 per 100,000.

Mortality and Survival Analysis of the Disease

According to the Porcel (2022) reported, mesothelioma causes more than 26,278 global deaths in 2020, while US Cancer Statistics recorded 2,114 US deaths in 2024.

Type-Specific Disease Burden and Epidemiology Analysis

Disease Type

Prevalence

Pleural mesothelioma

According to Asbestos.com and The Mesothelioma Center, pleural mesothelioma develops in the lining of the lungs and accounts for 75%–80% of all mesothelioma cases.

Peritoneal mesothelioma

As per Asbestos.com and The Mesothelioma Center, peritoneal mesothelioma develops in the abdominal lining and accounts for 10%–20% of all cases.

Pericardial mesothelioma

According to Asbestos.com and The Mesothelioma Center, pericardial mesothelioma develops in the lining around the heart and accounts for approximately 1% of all cases.

Testicular mesothelioma

As reported by Asbestos.com and The Mesothelioma Center, testicular mesothelioma develops in the tunica vaginalis surrounding the testes and accounts for less than 1% of cases.

Mesothelioma – Number of Cases by Country

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Country-wise Mesothelioma Epidemiology

The mesothelioma epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

Country

Key Insights

United States

According to the Centers for Disease Control and Prevention (2022 data), 2,669 cases were reported. US Cancer Statistics (2026) recorded 2,114 deaths in 2024, with an age-adjusted death rate of 0.5 per 100,000.

Germany

Historical asbestos consumption in industrial and construction activities contributes to the country’s mesothelioma burden. Regional differences in past asbestos exposure between eastern and western Germany have also been associated with differences in mortality patterns.

France

Historical asbestos exposure in occupational settings, including construction and work involving asbestos-containing materials, remains an important factor. The long interval between exposure and disease onset can sustain the disease burden even after asbestos use has been banned.

Italy

According to Jung et al. (2026), Italy’s Lombardy region recorded more than 7,900 mesothelioma cases between 2000 and 2020. Historical occupational asbestos exposure, including in construction and industrial settings, is relevant to the country’s epidemiological burden.

Spain

According to Porcel (2022), Spain recorded 586 new mesothelioma cases and 504 deaths in 2020. Historical asbestos use and occupational exposure are relevant factors when assessing the continuing burden of the disease.

United Kingdom

According to Harrison et al. (2022), approximately 2,700 new mesothelioma cases are diagnosed annually in the United Kingdom. Historical occupational exposure to asbestos, particularly among workers in construction and other exposed industries, contributes to the continuing disease burden.

Japan

According to Indriyati et al. (2025), Japan’s mesothelioma incidence is expected to peak between 2030 and 2039. Historical asbestos use in construction and the anticipated demolition of asbestos-containing buildings may sustain occupational exposure risks.

India

Historical and ongoing occupational exposure risks associated with asbestos-containing construction materials, building maintenance, and demolition are relevant considerations when assessing mesothelioma epidemiology. Exposure prevention and recognition of cases associated with occupational contact are important factors in understanding the disease burden.

Key Market Gaps, Untapped Opportunities, and Emerging Growth Areas in the Regional Disease Epidemiology Landscape

Mesothelioma management across the United States, Germany, France, Italy, Spain, the United Kingdom, Japan, and India faces challenges related to delayed diagnosis, limited early-detection approaches, and the disease's long latency following asbestos exposure. Opportunities include improving awareness among previously exposed populations, strengthening diagnostic pathways, and expanding access to specialist evaluation and multidisciplinary care. Emerging treatment needs include more effective therapies for advanced disease, improved patient selection for immunotherapy, and strategies to manage recurrence. India warrants further assessment of asbestos exposure and diagnostic access, while country-level epidemiological comparisons are needed to identify regional priorities.

Mesothelioma: Treatment Overview

Mesothelioma treatment depends on the disease stage, tumor location, histological subtype, and the patient's overall health. Options include surgery for selected patients with resectable disease, chemotherapy, immunotherapy, and radiation therapy. Platinum-based chemotherapy, commonly combining pemetrexed with cisplatin or carboplatin, remains an important treatment approach. Immune checkpoint inhibitors, including nivolumab and ipilimumab, are used in eligible patients, while other immunotherapy combinations may be considered according to clinical indications and local approvals. Multimodal treatment may combine surgery with systemic therapy or radiation in carefully selected cases. Systemic anticancer therapy is a relevant term for these treatment approaches.

Key Questions Answered

  • What is the current and projected burden of mesothelioma across the 8 major markets?
  • Which countries across the 8 major markets account for the highest mesothelioma patient populations and fastest growth rates?
  • What is the diagnosed versus undiagnosed patient population of mesothelioma across key countries in the 8 major markets?
  • Which countries demonstrate the largest gaps in screening, early diagnosis, and disease awareness of mesothelioma across the 8 major markets?
  • What are the major drivers contributing to the increasing burden of mesothelioma across the 8 major markets?
  • How do major comorbidities and risk factors influence mesothelioma epidemiology trends across the 8 major markets?
  • What are the regional trends in advanced disease progression, treatment uptake, and patient management of mesothelioma across the 8 major markets?
  • Which patient segments represent the highest unmet clinical need in the mesothelioma landscape across the 8 major markets?
  • Which therapeutic areas linked to mesothelioma are expected to witness the strongest growth opportunities across the 8 major markets?
  • How is the mesothelioma epidemiology landscape expected to evolve over the next 5 to 10 years across the 8 major markets?
  • Which countries across the 8 major markets offer the most attractive market opportunities based on mesothelioma epidemiology and healthcare infrastructure?
  • Which epidemiological trends are expected to influence future drug development and market access strategies for mesothelioma across the 8 major markets?

Scope of the Mesothelioma Epidemiology Report

  • The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of mesothelioma based on several factors.
  • Mesothelioma Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
  • The mesothelioma report helps to identify the patient population, and the unmet needs are highlighted along with an assessment of the disease's risk and burden.

Related Reports

Malignant Mesothelioma Pipeline Analysis

Malignant Mesothelioma Therapeutics Market

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

Report Features

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Base Year

2025

Historical Period

2019-2025

Forecast Period

2026-2035

Epidemiology Statistics Provided

  • Diagnosed Prevalent Cases
  • Type-Specific Cases
  • Gender-Specific Cases
  • Age-Specific Cases

Segmentation Provided

  • Epidemiology by Age Group
  • Epidemiology by Gender
  • Epidemiology by Type of Disease
  • Epidemiology by Region

Geographies Covered

  • United States
  • Germany
  • Italy
  • France
  • Spain
  • United Kingdom
  • Japan
  • India

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