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Report Overview

Venous thromboembolism (VTE) is a condition characterized by blood clots in the veins, including deep vein thrombosis and pulmonary embolism. According to Aaron M. Wendelboe et al. (2022), the global annual incidence of VTE is estimated at 0.75-2.69 cases per 1,000 people. As per the venous thromboembolism epidemiology forecast by Expert Market Research, this thrombotic disorder remains an important public health concern.

2025

Base Year

2019-2025

Historical Period

2026-2035

Forecast Period

Venous Thromboembolism – Number of Cases by Year

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Venous Thromboembolism Epidemiology Forecast Report Coverage

Expert Market Research's “Venous Thromboembolism Epidemiology Forecast Report 2026-2035” offers comprehensive information on the prevalence and demographics of venous thromboembolism. It projects the future incidence and prevalence rates of Venous Thromboembolism cases across various populations. The study covers age, gender, and type as major determinants of the venous thromboembolism population. The report highlights patterns in the prevalence of venous thromboembolism over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of venous thromboembolism in the 8 major markets.

Regions Covered

  • United States
  • Germany
  • France
  • Italy
  • Spain
  • United Kingdom
  • Japan
  • India

Venous Thromboembolism Understanding: Disease Overview

Venous thromboembolism (VTE) is a condition in which blood clots form in the venous circulation, potentially obstructing blood flow and causing serious complications. It primarily includes deep vein thrombosis (DVT), in which clots develop in deep veins, usually in the legs, and pulmonary embolism (PE), which occurs when a clot travels to the lungs. VTE develops when blood flow slows, the vessel wall is damaged, or blood becomes more prone to clotting. Major risk factors include surgery, prolonged immobility, cancer, and advanced age.

Key Report Insights

Parameter

Insight

Largest Patient Pool

United States

Fastest Growing Region

India

High-Risk Population

Older adults, hospitalized patients, individuals undergoing surgery, people with cancer, and those experiencing prolonged immobility.

Key Diagnostic Method

Duplex ultrasonography for deep vein thrombosis and computed tomography pulmonary angiography for pulmonary embolism.

Major Risk Factor

Prolonged immobility, recent surgery or hospitalization, active cancer, and previous VTE are important risk factors.

Major gap in the market

Underdiagnosis, nonspecific symptoms, and uneven availability of reliable epidemiological data and timely diagnostic services.

Venous Thromboembolism Epidemiology Perspective

The venous thromboembolism epidemiology division offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for the venous thromboembolism epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for venous thromboembolism and their trends. The data is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.

Epidemiology Segment

Key Insights

Diagnosed Prevalent Cases of the Disease

According to Aaron M. Wendelboe et al. (2022), the global annual incidence of venous thromboembolism (VTE) is estimated at 0.75-2.69 cases per 1,000 people. Up to 60% of VTE events occur during or within three months after hospital admission, accounting for approximately 10 million cases globally.

Gender-Specific Cases of the Disease

As per Lucia Cayuela et al. (2025), Spain recorded 59,515 VTE-related deaths between 1999 and 2022, with women accounting for 59.4% and men for 40.6%. The findings also indicate that mortality patterns vary by sex and age, supporting gender-specific epidemiological assessments.

Age-Specific Cases of the Disease

According to TROMBO.info, age is a major risk factor for thrombosis and pulmonary embolism, with most VTE patients older than 65 years. The increasing number of older adults affected by VTE highlights the importance of monitoring age-related disease burden.

Ethnicity-Wise Cases of the Disease

Epidemiological patterns may vary across populations because of differences in demographic characteristics, underlying risk factors, and healthcare settings. The supplied evidence also highlights VTE in the North Indian population, particularly among patients undergoing major lower-limb surgery.

Mortality and Survival Analysis of the Disease

According to the Centers for Disease Control and Prevention (CDC), an estimated 60,000-100,000 Americans die from VTE annually. Approximately 25% of people with pulmonary embolism experience sudden death as their first symptom, while one-third of VTE patients experience recurrence within 10 years.

Type-Specific Disease Burden and Epidemiology Analysis

Disease Type

Prevalence

Deep vein thrombosis (DVT)

A major manifestation of venous thromboembolism, representing a substantial proportion of VTE cases.

Pulmonary embolism (PE)

A serious manifestation of venous thromboembolism that occurs in a smaller subset of cases but contributes significantly to VTE-related mortality.

Venous Thromboembolism – Number of Cases by Country

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Country-wise Venous Thromboembolism Epidemiology

The venous thromboembolism epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

Country

Key Insights

United States

According to the Centers for Disease Control and Prevention (CDC), up to 900,000 people in the United States are affected by VTE annually, and approximately 60,000-100,000 Americans die from the condition each year. Safura Khubdast et al. (2024) reported an estimated VTE prevalence of 422 per 100,000, projected to reach 567 per 100,000 by 2050.

Germany

According to Safura Khubdast et al. (2024), a study in Germany reported a VTE prevalence of 7.8% among patients in nonsurgical intensive care units. This finding highlights the burden observed in critically ill populations rather than the general population.

France

According to Aram Hovhannisyan et al. (2026), France recorded an overall VTE prevalence of 1.5% in 2022. The age-standardized annual incidence among hospitalized patients was 103.8 cases per 100,000 person-years.

Italy

In Italy, the prevalence of venous thromboembolism may be influenced by population aging, increasing exposure to chronic diseases, hospitalization, surgical procedures, and prolonged immobility. Improved diagnostic practices and greater recognition of thromboembolic events may also contribute to the identification of cases.

Spain

According to Lucia Cayuela et al. (2025), Spain recorded 59,515 VTE-related deaths from 1999 to 2022. Women accounted for 59.4% of deaths and men for 40.6%. Age-standardized mortality rates declined nationally for both sexes, although regional and demographic differences persisted.

United Kingdom

As reported by M. Hey et al. (2025), 13,260 deaths in the United Kingdom had VTE recorded on the death certificate between April 2023 and April 2024. Hospital-acquired VTE represented an important preventable contributor to thromboembolism-related morbidity and mortality.

Japan

In Japan, the growing proportion of older adults may contribute to the venous thromboembolism burden, alongside age-related comorbidities, hospitalization, cancer, and reduced mobility. Increasing recognition of thromboembolic complications and changes in healthcare utilization may further influence reported disease prevalence.

India

According to Amrit Goyal et al. (2025), DVT affects approximately one person per 1,000 in the Indian general population. Pulmonary embolism incidence is estimated at 39-115 cases per 100,000 people annually, while major lower-limb surgery is associated with an increased risk of DVT.

Key Market Gaps, Untapped Opportunities, and Emerging Growth Areas in the Regional Disease Epidemiology Landscape

Venous thromboembolism presents opportunities to improve early detection, prevention, and access to evidence-based treatment across the United States, Germany, France, Italy, Spain, the United Kingdom, Japan, and India. A major unmet need is the timely identification of patients whose symptoms are nonspecific or whose risk increases following hospitalization, surgery, cancer treatment, or prolonged immobility. Another gap is the limited availability of comparable country-level epidemiological data, which complicates assessment of disease burden and healthcare needs. Opportunities include standardized risk-assessment protocols, improved diagnostic pathways, appropriate thromboprophylaxis, and follow-up to reduce recurrent events.

Venous Thromboembolism: Treatment Overview

Venous thromboembolism treatment primarily aims to prevent clot extension, reduce the risk of pulmonary embolism, and prevent recurrence. Anticoagulants, including direct oral anticoagulants, low-molecular-weight heparin, and vitamin K antagonists, are commonly used to inhibit further clot formation. Thrombolytic therapy may be considered for selected patients with severe pulmonary embolism, while catheter-based interventions or surgical embolectomy may be required in specific high-risk cases. Inferior vena cava filters may be considered when anticoagulation is contraindicated in selected patients. Treatment duration depends on clot location, recurrence risk, underlying causes, and bleeding risk.

Key Questions Answered

  • What is the current and projected burden of venous thromboembolism across the 8 major markets?
  • Which countries across the 8 major markets account for the highest venous thromboembolism patient populations and fastest growth rates?
  • What is the diagnosed versus undiagnosed patient population of venous thromboembolism across key countries in the 8 major markets?
  • Which countries demonstrate the largest gaps in screening, early diagnosis, and disease awareness of venous thromboembolism across the 8 major markets?
  • What are the major drivers contributing to the increasing burden of venous thromboembolism across the 8 major markets?
  • How do major comorbidities and risk factors influence venous thromboembolism epidemiology trends across the 8 major markets?
  • What are the regional trends in advanced disease progression, treatment uptake, and patient management of venous thromboembolism across the 8 major markets?
  • Which patient segments represent the highest unmet clinical need in the venous thromboembolism landscape across the 8 major markets?
  • Which therapeutic areas linked to venous thromboembolism are expected to witness the strongest growth opportunities across the 8 major markets?
  • How is the venous thromboembolism epidemiology landscape expected to evolve over the next 5 to 10 years across the 8 major markets?
  • Which countries across the 8 major markets offer the most attractive market opportunities based on venous thromboembolism epidemiology and healthcare infrastructure?
  • Which epidemiological trends are expected to influence future drug development and market access strategies for venous thromboembolism across the 8 major markets?

Scope of the Venous Thromboembolism Epidemiology Report

  • The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of venous thromboembolism based on several factors.
  • Venous Thromboembolism Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
  • The venous thromboembolism report helps to identify the patient population, and the unmet needs are highlighted along with an assessment of the disease's risk and burden.

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Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

Report Features

Details

Base Year

2025

Historical Period

2019-2025

Forecast Period

2026-2035

Epidemiology Statistics Provided

  • Diagnosed Prevalent Cases
  • Type-Specific Cases
  • Gender-Specific Cases
  • Age-Specific Cases

Segmentation Provided

  • Epidemiology by Age Group
  • Epidemiology by Gender
  • Epidemiology by Type of Disease
  • Epidemiology by Region

Geographies Covered

  • United States
  • Germany
  • Italy
  • France
  • Spain
  • United Kingdom
  • Japan
  • India

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