Piperazine Price Trend and Forecast 2026-2027

Piperazine is a cyclic diamine produced from ethanolamines or ethylene dichloride and ammonia, often as a co-product of ethyleneamines. It is used as a pharmaceutical intermediate for anthelmintics and quinolone antibiotics, in carbon dioxide capture solvents, polymers, corrosion inhibitors and epoxy curing agents. China and India are the major producers, while Europe and the United States are principally importers.

Pricing has increased steadily through 2026. The global average rose from USD 2.90 per kg in the fourth quarter of 2025 to USD 2.95 in the first quarter and USD 3.08 in the second, an increase of about 6 percent, with Europe at USD 3.72, the United States at USD 3.42, India at USD 2.75 and China at USD 2.45 in the second quarter. Ethyleneamines rose from USD 2.84 per kg to USD 2.98 over the same period.

Piperazine Prices in October 2026

As of the latest quarterly assessment, global piperazine is benchmarked at about USD 3.08 per kg, with China the lowest-priced origin at USD 2.45 per kg and Europe the highest at USD 3.72 per kg.

• Amine price increases: BASF announced in March that commodity amine prices in Europe would rise by up to 30 percent, and increased ethylenediamine and diethylenetriamine prices in North America by about USD 0.33 per kg, citing higher raw material, energy and logistics costs.
• Ethanolamine feedstock: The global average price of monoethanolamine rose from USD 1.296 per kg in the fourth quarter of 2025 to USD 1.331 in the first quarter, on firmer ammonia and tighter ethylene oxide supply, which raises piperazine production costs.
• Pharmaceutical demand: United States prices were supported by pharmaceutical restocking in early 2026, while India's generics industry provides a growing demand base, although the use of piperazine as a human anthelmintic has declined as newer drugs gained favour.
• Energy and logistics: Brent averaged USD 114 per barrel in September, according to the US Energy Information Administration, and the Strait of Hormuz carries about 35 percent of India's and 30 percent of China's organic chemical imports, which keeps freight and energy costs elevated.

Supplier news: Eastman announced in March amine price increases effective April, including an increase of about USD 0.20 per kg on diethylamine, which supports prices in the short term, while lower-cost supply from China and India, the lowest-priced origins, should moderate piperazine prices over the long term.

Piperazine Price Forecast for 2026

Expect steady gains across all four markets through H2 2026 as pharmaceutical intermediate demand continues its gradual growth. China should retain its cost advantage given its scale of production capacity. Europe's premium should persist given its concentrated pharmaceutical-grade manufacturing base and stricter quality standards. Growing demand from specialty polymer and corrosion-inhibitor applications is worth watching as a structural, if still modest, offset to any softening in the traditional anthelmintic market.

Taken together, the 4 markets in this report averaged a 4.6% increase quarter on quarter through the first half of 2026, a pace we expect to broadly continue barring a shift in the underlying cost or demand picture described above.

For the Quarter Ending June 2026

Piperazine Prices Q2 2026:

• China: USD 2.45/KG
• United States: USD 3.42/KG
• India: USD 2.75/KG
• Europe: USD 3.72/KG

Piperazine Prices in China

China reached USD 2.45/KG in Q2 2026, ample production capacity met firming feedstock costs, ranking it the most affordable among the 4 markets this report follows.

Why did the price of Piperazine change in Q2 2026 in China?

Ample production capacity met firming feedstock costs, supporting a steady increase, working out to China trading about 20.6% below this quarter's 4-region average.

Measured against China's own average pace of 2.7% a quarter across the six quarters this report tracks, this move came in faster than that pace.

Piperazine Prices in United States

United States rose 4.3% to USD 3.42/KG in Q2 2026, firm pharmaceutical intermediate demand kept US pricing climbing in step with the broader feedstock trend, placing it the 2nd most expensive across the 4 regions covered in this report.

Why did the price of Piperazine change in Q2 2026 in United States?

Firm pharmaceutical intermediate demand kept US pricing climbing in step with the broader feedstock trend, leaving United States running roughly 10.9% above the 4-region average for the quarter.

That is faster than the 2.3% average quarterly move United States has posted across the six quarters this report tracks.

Piperazine Prices in India

USD 2.75/KG. That is where India landed in Q2 2026, up 5.0% from USD 2.62/KG in Q1 2026, putting it the 3rd most expensive of the 4 markets tracked this quarter.

Why did the price of Piperazine change in Q2 2026 in India?

Growing domestic pharmaceutical manufacturing demand supported a firm quarter, with India now sitting about 10.9% below the 4-region average this quarter.

India has averaged 2.3% a quarter over the six quarters this report tracks; this move came in faster than that longer-run pace.

Piperazine Prices in Europe

Europe's price gained 3.9% to USD 3.72/KG, strict pharmaceutical-grade manufacturing standards kept Europe at the top of this group, making it the priciest of the 4 markets tracked here this quarter.

Why did the price of Piperazine change in Q2 2026 in Europe?

Strict pharmaceutical-grade manufacturing standards kept Europe at the top of this group, which puts Europe roughly 20.6% above the average across the 4 regions this report tracks.

Set against a 2.1% average quarterly pace over the six quarters this report tracks, Europe's move this quarter landed faster than that trend.

For the Quarter Ending March 2026

Piperazine Prices Q1 2026:

• China: USD 2.32/KG
• United States: USD 3.28/KG
• India: USD 2.62/KG
• Europe: USD 3.58/KG

Piperazine Prices in China

China reached USD 2.32/KG in Q1 2026, feedstock costs firmed modestly as the year opened, ranking it the most affordable among the 4 markets this report follows.

Why did the price of Piperazine change in Q1 2026 in China?

Feedstock costs firmed modestly as the year opened, carrying through to a steady early-year increase, working out to China trading about 21.4% below this quarter's 4-region average.

Measured against China's own average pace of 2.7% a quarter across the six quarters this report tracks, this move came in slower than that pace.

Piperazine Prices in United States

United States rose 1.8% to USD 3.28/KG in Q1 2026, early-year pharmaceutical sector restocking supported a firm start to 2026, placing it the 2nd most expensive across the 4 regions covered in this report.

Why did the price of Piperazine change in Q1 2026 in United States?

Early-year pharmaceutical sector restocking supported a firm start to 2026, leaving United States running roughly 11.2% above the 4-region average for the quarter.

That is slower than the 2.3% average quarterly move United States has posted across the six quarters this report tracks.

Piperazine Prices in India

USD 2.62/KG. That is where India landed in Q1 2026, up 1.7% from USD 2.58/KG in Q4 2025, putting it the 3rd most expensive of the 4 markets tracked this quarter.

Why did the price of Piperazine change in Q1 2026 in India?

Growing domestic demand carried prices higher as the new year began, with India now sitting about 11.2% below the 4-region average this quarter.

India has averaged 2.3% a quarter over the six quarters this report tracks; this move came in slower than that longer-run pace.

Piperazine Prices in Europe

Europe's price gained 1.7% to USD 3.58/KG, consistent demand from the region's established pharmaceutical industry supported a steady early-year gain, making it the priciest of the 4 markets tracked here this quarter.

Why did the price of Piperazine change in Q1 2026 in Europe?

Consistent demand from the region's established pharmaceutical industry supported a steady early-year gain, which puts Europe roughly 21.4% above the average across the 4 regions this report tracks.

Set against a 2.1% average quarterly pace over the six quarters this report tracks, Europe's move this quarter landed slower than that trend.

Quarterly Piperazine Price Trends

The global average climbed steadily across the window, from USD 2.75/KG in Q1 2025 to USD 3.08 by Q2 2026, a gain of 12.2% over six quarters.

What was Piperazine Price in 2025?

Looking back at 2025, the global piperazine average ran from about USD 2.75/KG in Q1 to USD 2.90 by Q4, a 5.4% increase across the year.

Piperazine Prices in China in 2025

China prices moved from about USD 2.15/KG in Q1 2025 to USD 2.28 by Q4, up roughly 5.9%. China closed the year ranked 4 of the 4 markets this report tracks.

Piperazine Prices in United States in 2025

United States prices moved from about USD 3.05/KG in Q1 2025 to USD 3.22 by Q4, up roughly 5.6%, leaving United States in 2 place among the 4 tracked markets heading into the new year.

Piperazine Prices in India in 2025

India prices moved from about USD 2.45/KG in Q1 2025 to USD 2.58 by Q4, up roughly 5.2%. That left India ranked 3 of 4 tracked markets heading into 2026.

Piperazine Prices in Europe in 2025

Europe prices moved from about USD 3.35/KG in Q1 2025 to USD 3.52 by Q4, up roughly 5.1%, placing Europe 1 of 4 tracked markets as 2025 closed out.

How We Can Help

Expert Market Research: Your Source for Real-Time Piperazine Price Intelligence

Tracking piperazine prices means tracking what actually moves them: ethylene dichloride, monoethanolamine, and ammonia costs, regional demand shifts, and the policy decisions that touch both. Our team maintains that view across every region in this report, refreshing it as conditions change.

Rather than a single static figure, our forecasts blend capacity data, feedstock cost trends, and demand signals from across the regions we cover, built specifically to support procurement budgeting and supplier negotiations.

Reach out to our analysts for a deeper regional breakdown, historical data extending beyond the six quarters shown here, or a custom piperazine sourcing analysis tailored to your specific procurement footprint.

We track anhydrous and hexahydrate piperazine pricing separately, since the choice between the two forms depends on a buyer's specific application rather than price alone, and we watch pharmaceutical-intermediate demand as a distinct thread from the traditional anthelmintic market.