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Report Overview

Malaria is a life-threatening parasitic disease transmitted to humans through the bites of infected female Anopheles mosquitoes. According to the World Health Organization (WHO), an estimated 282 million cases and 610,000 deaths occurred globally in 2024, highlighting the substantial burden of this mosquito-borne disease. As per the malaria epidemiology forecast by Expert Market Research, malaria remains a significant global public health concern.

2025

Base Year

2019-2025

Historical Period

2026-2035

Forecast Period

Malaria – Number of Cases by Year

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Malaria Epidemiology Forecast Report Coverage

Expert Market Research's “Malaria Epidemiology Forecast Report 2026-2035” offers comprehensive information on the prevalence and demographics of malaria. It projects the future incidence and prevalence rates of malaria cases across various populations. The study covers age, gender, and type as major determinants of the malaria population. The report highlights patterns in the prevalence of malaria over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of malaria in the 8 major markets.

Regions Covered

  • United States
  • Germany
  • France
  • Italy
  • Spain
  • United Kingdom
  • Japan
  • India

Malaria Understanding: Disease Overview

Malaria is a life-threatening infectious disease caused by Plasmodium parasites and transmitted to humans through the bites of infected female Anopheles mosquitoes. The major species responsible for human malaria include Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, and Plasmodium knowlesi. The infection primarily affects red blood cells and can cause fever, chills, headache, fatigue, and anemia. Severe cases may lead to organ dysfunction and death, particularly among young children, pregnant women, and individuals with limited immunity. Malaria epidemiology varies considerably across regions depending on transmission intensity and prevention measures.

Key Report Insights

Parameter

Insight

Largest Patient Pool

India

Fastest Growing Region

India

High-Risk Population

Children under five, pregnant women, and individuals with limited immunity or exposure to malaria-endemic areas.

Key Diagnostic Method

Blood smear microscopy, supported by rapid diagnostic tests (RDTs) and molecular testing when indicated.

Major Risk Factor

Exposure to infected female Anopheles mosquitoes, particularly in malaria-endemic areas.

Major gap in the market

Delayed diagnosis, limited access to timely testing in some endemic settings, and inadequate recognition of imported malaria in non-endemic countries.

Malaria Epidemiology Perspective

The malaria epidemiology division offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for the malaria epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for malaria and their trends. The data is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.

Epidemiology Segment

Key Insights

Diagnosed Prevalent Cases of the Disease

According to the World Health Organization, an estimated 282 million malaria cases were reported across 80 countries in 2024, representing an increase of approximately 9 million cases compared with 2023. The global burden remains concentrated in the African region.

Gender-Specific Cases of the Disease

As per Abebaw Setegn et al. (2025), a study involving 528 participants found malaria prevalence of 17.6% among males (48 of 273) and 14.5% among females (37 of 255). These findings reflect the study population rather than global gender-specific prevalence.

Age-Specific Cases of the Disease

According to Abebaw Setegn et al. (2025), participants aged 15–24 years had the highest malaria prevalence at 25.2%, followed by those aged 6–14 years at 22.6%. Participants aged 45 years and older had the lowest prevalence, at 6.9%.

Ethnicity-Wise Cases of the Disease

Malaria burden varies geographically with exposure to transmission, travel patterns, and access to preventive measures. According to Fissha Brhane Mesele et al. (2025), sub-Saharan Africa bears a disproportionately high share of global cases, although ethnicity-specific prevalence figures were not provided in the supplied information.

Mortality and Survival Analysis of the Disease

According to the World Health Organization, malaria caused an estimated 610,000 deaths globally in 2024, compared with 598,000 in 2023. Children younger than five years accounted for approximately 75% of malaria deaths in the African region, highlighting their substantial mortality burden.

Type-Specific Disease Burden and Epidemiology Analysis

Disease type

Prevalence

Plasmodium falciparum

Identified as the more virulent malaria species in the information provided by Abebaw Setegn et al. (2025). It is also the most frequently diagnosed species in Spain, according to Malaria en España et al. (2024).

Plasmodium vivax

Identified as one of the main malaria species associated with complications, according to Abebaw Setegn et al. (2025).

Plasmodium ovale

Recognized as one of the five Plasmodium species known to infect humans, according to Abebaw Setegn et al. (2025).

Plasmodium malariae

Recognized as a malaria-causing species in the information provided by Abebaw Setegn et al. (2025).

Plasmodium knowlesi

Recognized as a malaria-causing species in the information provided by Abebaw Setegn et al. (2025).

Malaria – Number of Cases by Country

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Country-wise Malaria Epidemiology

The malaria epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

Country

Key Insights

United States

According to the Centers for Disease Control and Prevention, approximately 2,000 malaria cases are reported annually, with nearly seven deaths per year on average during 2007–2022.

Germany

According to Ravishtaashini Vanitha et al. (2025), Germany recorded an annual average of 827.10 confirmed malaria cases over the period analyzed.

France

As per Ravishtaashini Vanitha et al. (2025), France accounted for 34.16% of confirmed malaria cases in Europe, averaging 2,391.70 cases annually over the analyzed period.

Italy

According to the Severe Malaria Observatory, Italy is not malaria-endemic, but approximately 600–700 imported cases are detected annually.

Spain

According to Malaria en España et al. (2024), Spain reports approximately 800 imported malaria cases annually, with Plasmodium falciparum the most frequently diagnosed species.

United Kingdom

According to Jo Salkeld et al. (2024), the United Kingdom reported 2,093 malaria cases in 2023, the highest annual total in 25 years.

Japan

According to Mitsunobu Toyosaki et al. (2025), Japan reports approximately 50–100 imported malaria cases annually, with no recent locally transmitted cases.

India

According to Data for India, an estimated 4.5 million new malaria cases occurred in 2023, down from approximately 33 million in 1990.

Key Market Gaps, Untapped Opportunities, and Emerging Growth Areas in the Regional Disease Epidemiology Landscape

Across the selected countries, malaria epidemiology differs considerably between endemic India and countries where cases are predominantly associated with international travel. In India, opportunities include strengthening early diagnosis, expanding access to rapid diagnostic tests, improving surveillance, and addressing gaps in prevention and treatment in affected communities. In the United States, Germany, France, Italy, Spain, the United Kingdom, and Japan, greater clinical awareness of travel-associated malaria and access to prompt laboratory confirmation remain important priorities. Improved diagnostic readiness and timely species-specific treatment can help reduce complications and prevent avoidable deaths.

Malaria: Treatment Overview

Malaria treatment depends on the infecting Plasmodium species, disease severity, geographic location, and local drug resistance patterns. Artemisinin-based combination therapies are recommended for uncomplicated P. falciparum malaria in many endemic settings. Chloroquine remains an option for infections caused by susceptible parasites, while severe malaria generally requires intravenous artesunate followed by a complete oral treatment course. P. vivax and P. ovale infections may require primaquine or tafenoquine for radical cure to eliminate dormant liver-stage parasites, following appropriate glucose-6-phosphate dehydrogenase deficiency testing. Antimalarial therapy is supported by early diagnosis, appropriate drug selection, and adherence to treatment guidelines.

Key Questions Answered

  • What is the current and projected burden of malaria across the 8 major markets?
  • Which countries across the 8 major markets account for the highest malaria patient populations and fastest growth rates?
  • What is the diagnosed versus undiagnosed patient population of malaria across key countries in the 8 major markets?
  • Which countries demonstrate the largest gaps in screening, early diagnosis, and disease awareness of malaria across the 8 major markets?
  • What are the major drivers contributing to the increasing burden of malaria across the 8 major markets?
  • How do major comorbidities and risk factors influence malaria epidemiology trends across the 8 major markets?
  • What are the regional trends in advanced disease progression, treatment uptake, and patient management of malaria across the 8 major markets?
  • Which patient segments represent the highest unmet clinical need in the malaria landscape across the 8 major markets?
  • Which therapeutic areas linked to malaria are expected to witness the strongest growth opportunities across the 8 major markets?
  • How is the malaria epidemiology landscape expected to evolve over the next 5 to 10 years across the 8 major markets?
  • Which countries across the 8 major markets offer the most attractive market opportunities based on malaria epidemiology and healthcare infrastructure?
  • Which epidemiological trends are expected to influence future drug development and market access strategies for malaria across the 8 major markets?

Scope of the Malaria Epidemiology Report

  • The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of malaria based on several factors.
  • Malaria Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
  • The malaria report helps to identify the patient population, and the unmet needs are highlighted along with an assessment of the disease's risk and burden.

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*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

Report Summary

Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

Report Features

Details

Base Year

2025

Historical Period

2019-2025

Forecast Period

2026-2035

Epidemiology Statistics Provided

  • Diagnosed Prevalent Cases
  • Type-Specific Cases
  • Gender-Specific Cases
  • Age-Specific Cases

Segmentation Provided

  • Epidemiology by Age Group
  • Epidemiology by Gender
  • Epidemiology by Type of Disease
  • Epidemiology by Region

Geographies Covered

  • United States
  • Germany
  • Italy
  • France
  • Spain
  • United Kingdom
  • Japan
  • India

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