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Acyclovir Pricing, Demand and Supply Overview
Acyclovir prices in Germany, the highest-cost reporting region, rose 2.8% in Q2 2026 to USD 47,800.00/MT from USD 46,500.00/MT in Q1, extending a sharp reversal from the gradual multi-quarter decline that had characterized this market through most of 2025. Globally, the average rose from USD 38,432.00/MT in Q1 to USD 39,546.00/MT in Q2, a 2.9% gain, following a jump of 10.3% in Q1 alone as elevated guanine and synthesis intermediate feedstock costs reversed the earlier softening trend. For H2 2026, a global average of USD 33,500.00-49,000.00/MT is expected, with elevated feedstock costs likely to keep this market firm.
Acyclovir is a synthetic guanosine analogue antiviral active pharmaceutical ingredient used in the treatment of herpes simplex virus, varicella-zoster virus, and related viral infections. Produced through a multi-step organic synthesis process using guanine as a key starting material, it is formulated into tablets, capsules, topical creams, and intravenous solutions for both prescription and hospital-administered treatment. Demand for this API remains structurally stable given its role as a first-line antiviral therapy, with consistent baseline consumption from dermatology, infectious disease, and hospital pharmacy channels across both developed and emerging markets. India and China together maintain substantial generic API manufacturing capacity, serving as key global supply hubs for this widely prescribed antiviral. Guanine and synthesis intermediate costs, dermatology and infectious disease treatment demand, and regional generic API manufacturing capacity are what drive prices in this market.
Acyclovir Price Forecast for 2026
The outlook for Acyclovir through H2 2026 stays firm, tracking elevated guanine and synthesis intermediate feedstock costs tied to the broader Strait of Hormuz-linked petrochemical cost environment. Steady demand from dermatology and infectious disease treatment channels, alongside consistent hospital pharmacy procurement, should continue supporting consumption even as the pace of further gains likely moderates from the sharp Q1 2026 spike that characterized every region covered here.
The main upside risk is a further tightening of guanine or synthesis intermediate feedstock availability, which would push production costs higher across every region. The main downside risk is a faster-than-expected normalization of feedstock costs combined with softer generic antiviral demand, which would ease some of the current price pressure.
| Region | 2026 Price Range (USD/MT) | Outlook |
| Global Average | 33,500.00 - 49,000.00 | Elevated feedstock costs keep this market firm |
| Germany | 44,000.00 - 51,000.00 | Established European formulator base sustains the highest cost |
| United States | 40,500.00 - 47,500.00 | Steady hospital pharmacy demand supports continued firmness |
| India | 31,000.00 - 36,500.00 | Growing generic API production drives continued gains |
| China | 27,000.00 - 32,000.00 | Large-scale API production capacity keeps this the most affordable market |
For the Quarter Ending June 2026
Acyclovir Prices Q2 2026:
- Germany: USD 47,800.00/MT
- United States: USD 44,200.00/MT
- India: USD 33,900.00/MT
- China: USD 29,700.00/MT
Acyclovir Prices in Germany
German Acyclovir prices averaged USD 47,800.00/MT in Q2 2026, the highest of any region tracked here, up 2.8% from USD 46,500.00/MT in Q1, as this market's established European formulator base continued sustaining the premium.
Why did the price of Acyclovir change in Q2 2026 in Germany?
Steady demand from established European formulators, tied to both prescription and hospital-administered antiviral treatment production, continued keeping this market at the top of the range tracked in this report.
Acyclovir Prices in the United States
US prices averaged USD 44,200.00/MT in Q2 2026, up 2.8% from USD 43,000.00/MT in Q1, as steady hospital pharmacy and dermatology treatment demand continued supporting this market.
Why did the price of Acyclovir change in Q2 2026 in the United States?
Consistent demand from hospital pharmacy channels and dermatology treatment providers kept US buyers active even as guanine and synthesis intermediate feedstock costs continued moving higher through the quarter.
Acyclovir Prices in India
Indian prices averaged USD 33,900.00/MT in Q2 2026, up 3.0% from USD 32,900.00/MT in Q1, as growing generic API manufacturing demand continued driving gains.
Why did the price of Acyclovir change in Q2 2026 in India?
Continued growth in demand from India's expanding generic antiviral API manufacturing sector kept buyers competing for available synthesis intermediates, supporting continued price gains.
Acyclovir Prices in China
Chinese prices, the lowest of the four regions, averaged USD 29,700.00/MT in Q2 2026, up 3.1% from USD 28,800.00/MT in Q1, as large-scale domestic API production capacity continued keeping this market comparatively affordable.
Why did the price of Acyclovir change in Q2 2026 in China?
Large-scale domestic API production capacity continued keeping Chinese offers the most competitive of any region tracked here, even as the broader guanine feedstock cost environment pushed prices modestly higher.
For the Quarter Ending March 2026
Acyclovir Prices Q1 2026:
- Germany: USD 46,500.00/MT
- United States: USD 43,000.00/MT
- India: USD 32,900.00/MT
- China: USD 28,800.00/MT
Acyclovir Prices in Germany
German prices surged 10.7% in Q1 2026 to USD 46,500.00/MT from USD 42,000.00/MT in Q4 2025, as guanine and synthesis intermediate feedstock costs spiked following the broader Middle East-linked energy market disruption.
Why did the price of Acyclovir change in Q1 2026 in Germany?
Guanine and synthesis intermediate prices surged sharply as the global feedstock repricing following Middle East escalation raised the cost basis across the entire antiviral API value chain, and that pressure flowed directly through to finished Acyclovir pricing across German formulator supply chains.
Acyclovir Prices in the United States
US prices surged 10.3% in Q1 2026 to USD 43,000.00/MT from USD 39,000.00/MT in Q4 2025, tracking the broader feedstock cost spike.
Why did the price of Acyclovir change in Q1 2026 in the United States?
Elevated guanine and synthesis intermediate feedstock costs, tied to the Middle East-linked energy market disruption, pushed US production expenses sharply higher, even as steady underlying hospital pharmacy demand kept this market fundamentally well supported.
Acyclovir Prices in India
Indian prices surged 10.0% in Q1 2026 to USD 32,900.00/MT from USD 29,900.00/MT in Q4 2025, tracking the broader Asian feedstock cost spike.
Why did the price of Acyclovir change in Q1 2026 in India?
Elevated crude oil and natural gas prices, following disruptions to global energy markets tied to the Middle East conflict, increased production costs for guanine feedstock, pushing Indian Acyclovir prices higher through the quarter.
Acyclovir Prices in China
Chinese prices surged 9.9% in Q1 2026 to USD 28,800.00/MT from USD 26,200.00/MT in Q4 2025, tracking the global guanine feedstock cost spike even as domestic production capacity remained substantial.
Why did the price of Acyclovir change in Q1 2026 in China?
Rising guanine and synthesis intermediate feedstock costs, tied to the broader Middle East-linked petrochemical cost environment, fed through to Chinese Acyclovir pricing even as the country's substantial domestic production capacity kept the pace of the increase comparatively moderate.
Quarterly Acyclovir Price Trends
Global Acyclovir prices eased gradually through most of 2025 as guanine and synthesis intermediate feedstock costs moderated, before accelerating sharply in Q1 2026 as rising feedstock costs, tied to the broader Middle East-linked energy market disruption, pushed prices to their highest levels of the period, a trend that continued into Q2 across every region tracked in this report.
| Quarter | Price (USD/MT) | QoQ Change | Direction |
| Q2 2026 | 39,546.00 | +2.9% | ↑ Rising |
| Q1 2026 | 38,432.00 | +10.3% | ↑ Rising |
| Q4 2025 | 34,840.00 | -2.4% | ↓ Falling |
| Q3 2025 | 35,680.00 | -2.3% | ↓ Falling |
| Q2 2025 | 36,520.00 | - | — Stable |
| Q3 2026 | In Progress | - | — In Progress |
What was Acyclovir Price in 2025?
Acyclovir eased across every market covered in this report through 2025, tracking moderating guanine and synthesis intermediate feedstock costs, before the Middle East-linked energy market disruption sharply reversed that trend in Q1 2026, pushing feedstock costs, and with them antiviral API production economics, higher across every region tracked here.
Acyclovir Prices in Germany in 2025
German prices eased from about USD 45,000.00/MT in Q1 2025 to USD 42,000.00/MT by Q4, down roughly 6.7%, before the sharp Q1 2026 reversal that followed.
Acyclovir Prices in the United States in 2025
US prices eased from about USD 42,000.00/MT in Q1 2025 to USD 39,000.00/MT by Q4, down roughly 7.1%, the steepest annual decline of the four regions.
Acyclovir Prices in India in 2025
Indian prices eased from about USD 32,000.00/MT in Q1 2025 to USD 29,900.00/MT by Q4, down roughly 6.6%, the smallest annual decline of the four regions.
Acyclovir Prices in China in 2025
Chinese prices eased from about USD 28,000.00/MT in Q1 2025 to USD 26,200.00/MT by Q4, down roughly 6.4%, before the sharp reversal that followed once feedstock costs spiked.
How We Can Help
Expert Market Research: Your Source for Real-Time Acyclovir Price Intelligence
Expert Market Research tracks Acyclovir prices continuously across every major producing and consuming region, combining guanine and synthesis intermediate cost data, dermatology and infectious disease treatment demand signals, and regional generic API manufacturing capacity trends into a single, regularly updated view of the market. Our team can help your procurement function benchmark current offers, plan purchases around the sharp reversal covered in this report, and build a defensible view of where this essential antiviral API is headed next. Reach out to our team for a tailored briefing or a deeper look at any of the regional markets covered here.
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Key Questions Answered in the Report
It is a synthetic guanosine analogue antiviral active pharmaceutical ingredient used in the treatment of herpes simplex virus, varicella-zoster virus, and related viral infections, formulated into tablets, capsules, topical creams, and intravenous solutions.
The Q2 2026 global average was USD 39,546.00/MT, ranging from USD 29,700.00/MT in China to USD 47,800.00/MT in Germany.
The global average rose from USD 34,840.00/MT in Q4 2025 to USD 38,432.00/MT in Q1 2026, a 10.3% jump, and then to USD 39,546.00/MT in Q2, tracking elevated guanine and synthesis intermediate feedstock costs.
Guanine and synthesis intermediate prices surged sharply as the global feedstock repricing following Middle East escalation raised the cost basis across the entire antiviral API value chain, reversing the gradual softening trend recorded through most of 2025.
The global average is expected in the USD 33,500.00-49,000.00/MT range, with elevated feedstock costs likely to keep this market firm.
China holds the lowest cost among the regions tracked here given large-scale API production capacity, while Germany carries the highest cost given its established European formulator base.
This report is updated monthly. For real-time pricing intelligence, connect with the Expert Market Research team.
Guanine and synthesis intermediate costs, dermatology and infectious disease treatment demand, and regional generic API manufacturing capacity.
India and China together maintain substantial generic API manufacturing capacity, serving as key global supply hubs, with Germany and the United States also significant producing and consuming markets tied to their established pharmaceutical formulation industries.
Buyers can monitor guanine and synthesis intermediate cost trends given their outsized influence on this market, time forward purchases around the quarterly breakdowns in this report, and benchmark supplier quotes against the tracked price ranges.
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