Doxepin HCl Price Trend and Forecast 2026-2027

Market Overview

Germany held the top of the four markets we track for the doxepin HCl through the first half of the year 2026 (H1 2026), with Q2 closing at a value of USD 252/KG, up 1.6% from the USD 248 in Q1. Worldwide, the average firmed to a value of USD 215/KG in Q2 2026, a gain of just a 1.4% percent over the Q1 figure of USD 212, as the API buyers held their procurement steady.

The doxepin HCl is an active pharmaceutical ingredient, made from the dibenzoxepinone intermediate and the hydrochloric acid. It is a tricyclic compound used in the antidepressant and the antihistamine formulations, including the topical anti-itch products. It is a low-volume specialty API, so the price sits high and moves in a narrow band compared with the bulk chemicals.

Two things move the doxepin HCl price the most: the dibenzoxepinone intermediate cost, and the regulated, low-volume API demand cycle. For the second half of 2026 (H2 2026), a range of an amount of USD 210 to 230/KG looks likely worldwide, supported by the steady formulation offtake and the firm intermediate costs.

Doxepin HCl Price Forecast for 2026

Supply looks steady through the H2 2026, with the dibenzoxepinone intermediate cost and the regulated demand setting the direction. The formulation buyers held their procurement steady through the H1, and that looks set to hold. China and the India keep the lower-cost API supply, while the United States and the Germany track higher on the regulated sourcing and the freight.

The market sits set for a firm and a narrow move, the way the specialty APIs usually trade. The bigger question for the buyers is how the intermediate cost moves, since that carries most of the finished-API price for a low-volume compound like this.

What could push the prices higher? A dibenzoxepinone intermediate spike, or a tightening of the GMP-approved supply. What could pull them lower? Softer formulation demand, or added low-cost API capacity in the Asia.

For the Quarter Ending June 2026

Doxepin HCl Prices Q2 2026:

• China: USD 178/KG
• India: USD 186/KG
• United States: USD 244/KG
• Germany: USD 252/KG

Doxepin HCl Prices in China

China firmed a value of 1.7% to the USD 178/KG, the producers passing through a little of the firmer dibenzoxepinone intermediate cost. The large API base kept the China among the lower-cost sources of the four.

Why did the price of Doxepin HCl change in Q2 2026 in China?

The firmer dibenzoxepinone intermediate cost lifted the offers, though the ample API base kept the gain small.

Doxepin HCl Prices in India

India moved up a value of 1.6% to the USD 186/KG, the export and the domestic formulation demand steady and the intermediate cost firming. The competitive API supply kept India close to the China on the price.

Why did the price of Doxepin HCl change in Q2 2026 in India?

The steady formulation demand met the firmer intermediate cost, with the competitive supply holding the move measured.

Doxepin HCl Prices in United States

The United States firmed a value of 1.7% to the USD 244/KG, the regulated formulation demand dependable while the sourcing and the compliance costs held firm. That kept the United States among the priciest of the four.

Why did the price of Doxepin HCl change in Q2 2026 in United States?

The dependable regulated demand met the firm sourcing and the compliance costs through the quarter.

Doxepin HCl Prices in Germany

Germany gained a value of 1.6% to the USD 252/KG, its regulated pharmaceutical demand holding firm. The compliance and the import-linked costs kept the German prices at the top of the four.

Why did the price of Doxepin HCl change in Q2 2026 in Germany?

The regulated demand held, and the compliance and the import-linked costs firmed alongside it.

For the Quarter Ending March 2026

Doxepin HCl Prices Q1 2026:

• China: USD 175/KG
• India: USD 183/KG
• United States: USD 240/KG
• Germany: USD 248/KG

Doxepin HCl Prices in China

China firmed a value of 2.3% to the USD 175/KG, the intermediate cost turning up as the year opened and the formulation buyers refilling the light inventories.

Why did the price of Doxepin HCl change in Q1 2026 in China?

The firmer intermediate cost met the formulation restocking as the year opened.

Doxepin HCl Prices in India

India rose a value of 2.2% to the USD 183/KG, the export API demand recovering with the new year and the intermediate cost firming.

Why did the price of Doxepin HCl change in Q1 2026 in India?

The recovering export API demand met the firmer intermediate cost into the new year.

Doxepin HCl Prices in United States

The United States firmed a value of 2.1% to the USD 240/KG, the regulated buyers restocking and the sourcing costs lifting the delivered value.

Why did the price of Doxepin HCl change in Q1 2026 in United States?

The regulated buyers restocked, and the sourcing costs lifted the delivered value.

Doxepin HCl Prices in Germany

Germany gained a value of 2.1% to the USD 248/KG, the regulated demand steady and the compliance-linked costs firming into the new year.

Why did the price of Doxepin HCl change in Q1 2026 in Germany?

The steady regulated demand met the firmer compliance-linked costs into the new year.

Quarterly Doxepin HCl Price Trends

The global average held a firm and a narrow path across the window, moving from a value of USD 204/KG in the Q1 2025 to the USD 215 by the Q2 2026, a net gain of about 5.4%. The low-volume specialty nature of the compound kept the swings small, with the dibenzoxepinone intermediate cost setting most of the direction across the quarters.

What was Doxepin HCl Price in 2025?

The year 2025 ran firm and quiet for the doxepin HCl. The global average moved from a value of USD 204/KG in the Q1 to the USD 207 by the Q4, a gain of about 1.5% across the year. The low-volume specialty demand held the market steady, with only a shallow Q3 dip, and the dibenzoxepinone intermediate cost set the pace throughout.

Doxepin HCl Prices in China in 2025

Chinese prices moved from a value of USD 168/KG in the Q1 2025 to the USD 171 by the Q4, up about 1.8%. The steady API demand and the firm intermediate cost held the market, and China stayed among the lower-cost sources of the four all year.

Doxepin HCl Prices in India in 2025

Indian prices firmed from a value of USD 176/KG in the Q1 to the USD 179 by the Q4, a gain of about 1.7%. The export and the domestic formulation demand held steady, and the competitive API supply kept India close to the China.

Doxepin HCl Prices in United States in 2025

The United States prices moved from a value of USD 232/KG in the Q1 to the USD 235 by the Q4, up about 1.3%. The regulated formulation demand kept the market firm, and the United States held among the priciest of the four all year.

Doxepin HCl Prices in Germany in 2025

German prices firmed from a value of USD 240/KG in the Q1 to the USD 243 by the Q4, a gain of about 1.3%. The regulated pharma demand kept the market steady, and the compliance and the import costs held Germany the dearest of the four.

How We Can Help

Expert Market Research: Your Source for Real-Time Doxepin HCl Price Intelligence

We keep a continuous watch on the doxepin HCl prices wherever it is produced or consumed at scale, tracing the causation through the dibenzoxepinone intermediate economics and the regulated, low-volume API demand. Our analysts track all four of the markets on a monthly basis, so the figures reflect the most current data at the time of the publication. Contact Expert Market Research today for the Doxepin HCl pricing data, the bespoke market analysis, and the strategic procurement advisory.