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The global gene synthesis market size was valued at USD 2.42 billion in 2023, driven by the increasing prevalence of genetic disorders across the globe. The market is anticipated to grow at a CAGR of 21.2% during the forecast period of 2024-2032 to achieve a value of USD 13.66 billion by 2032.
Gene synthesis is a method which is used to generate or produce artificial genes in the laboratory. It enables the scientists to design and build custom DNA sequences that can later be used to manipulate the behaviours and characteristics of organisms or humans. Scientists insert these altered DNA into the body of the target and then observe the outcomes of the underlying experiments or trials. The complete process of gene synthesis consists of five steps including design, synthesis, assembly, verification, and expression. At first, the designing of sequence is being done by keeping the expected functionality of the living cell in mind. Then the gene synthesis takes place which is processed chemically. The basic building blocks of DNA (adenine, thymine, guanine, and cytosine) are linked together in the order specified by the design. The small, synthesized fragments are then assembled into full-length genes. This can be done with the use of a variety of methods such as polymerase chain reaction (PCR). Then happens the verification.
It is basically matching the intended design with the outcome of assembled gene. The synthesized gene at this stage is ready to be inserted into a living cell (like a bacteria or yeast cell) to "express" the gene, which means that the cell will read the DNA sequence and produce the protein that the gene has been coded for.
Gene synthesis can be used in various fields including vaccine development, drug discovery, agricultural biotechnology, and many other areas of biotechnology and life sciences. The increasing demand of gene synthesis in the fields such as pharmaceuticals and biotechnology industries has been driving the global gene synthesis market growth. The gene synthesis is widely applicable in the development of drugs. Pharmaceutical companies along with biotech companies are suing gene synthesis to develop new therapies such as personalized medicines and vaccines.
Additionally, the increasing technological advancements in the field of synthetic biology are making gene synthesis to be more efficient and cost-effective. This includes updating gene design software, DNA synthesis and assembly technologies, and techniques for integrating synthetic genes into host organisms. The market is witnessing increased funding and investment from both public and private sources. This is leading to increased rate of research and development activities and more innovation. The global gene synthesis market development is driven by the increased focus on using gene synthesis for agricultural applications, such as the development of genetically modified crops with improved traits.
Market Breakup by Components
Market Breakup by Gene Therapy
Market Breakup by Application
Market Breakup by Gene Synthesis Type
Market Breakup by Region
The increasing research and development in the fields of synthetic biology and genomics is driving demand for gene synthesis services. This is especially prevalent in sectors pharmaceuticals sector along with biotechnology, and academia. The increasing technological advancements in the field have made gene synthesis more efficient, accurate, and affordable which is helping in the market growth. Developments in next-generation sequencing, bioinformatics, and gene editing technologies (like CRISPR) are also directly contributing to market growth. The gene synthesis has been increasingly used in the discovery and development of novel drugs and therapeutics, including personalized medicines and vaccines.
Additionally, the increasing prevalence of genetic disorders worldwide is also driving the demand for effective genetic therapies boosting the market. There has been a rise in funding and investments from government and private sectors for research activities that are fuelling the global gene synthesis market expansion.
The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:
REPORT FEATURES | DETAILS |
Base Year | 2023 |
Historical Period | 2017-2023 |
Forecast Period | 2024-2032 |
Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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Breakup by Components |
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Breakup by Gene Therapy |
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Breakup by Application |
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Breakup by Gene Synthesis Type |
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Breakup by Region |
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Market Dynamics |
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Competitive Landscape |
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Companies Covered |
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*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.
1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage – Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Global Gene Synthesis Market Overview
3.1 Global Gene Synthesis Market Historical Value (2017-2023)
3.2 Global Gene Synthesis Market Forecast Value (2024-2032)
4 Global Gene Synthesis Market Landscape
4.1 Gene Synthesis: Developers Landscape
4.1.1 Analysis by Year of Establishment
4.1.2 Analysis by Company Size
4.1.3 Analysis by Region
4.2 Gene Synthesis: Product Landscape
4.2.1 Analysis by Type
4.2.2 Analysis by Technology
4.2.3 Analysis by Applications
5 Global Gene Synthesis Market Dynamics
5.1 Market Drivers and Constraints
5.2 SWOT Analysis
5.3 Porter’s Five Forces Model
5.4 Key Demand Indicators
5.5 Key Price Indicators
5.6 Industry Events, Initiatives, and Trends
5.7 Value Chain Analysis
6 Global Gene Synthesis Market Segmentation
6.1 Global Gene Synthesis Market by Components
6.1.1 Market Overview
6.1.2 Synthesizer
6.1.3 Consumables
6.1.4 Software and Services
6.2 Global Gene Synthesis Market by Gene Therapy
6.2.1 Market Overview
6.2.2 Standard Gene
6.2.3 Express Gene
6.2.4 Complex Gene
6.2.5 Others
6.3 Global Gene Synthesis Market by Application
6.3.1 Market Overview
6.3.2 Synthetic Biology
6.3.3 Genetic Engineering
6.3.4 Vaccine Design
6.3.5 Therapeutics Antibodies
6.3.6 Others
6.4 Global Gene Synthesis Market by Gene Synthesis Type
6.4.1 Market Overview
6.4.2 Gene Library Synthesis
6.4.3 Solid Phase Synthesis
6.4.4 Chip-Based DNA Synthesis
6.4.5 PCR-Based Enzyme Synthesis
6.5 Global Gene Synthesis Market by Region
6.5.1 Market Overview
6.5.2 North America
6.5.3 Europe
6.5.4 Asia Pacific
6.5.5 Latin America
6.5.6 Middle East and Africa
7 North America Gene Synthesis Market
7.1 Market Share by Country
7.2 United States of America
7.3 Canada
8 Europe Gene Synthesis Market
8.1 Market Share by Country
8.2 United Kingdom
8.3 Germany
8.4 France
8.5 Italy
8.6 Others
9 Asia Pacific Gene Synthesis Market
9.1 Market Share by Country
9.2 China
9.3 Japan
9.4 India
9.5 ASEAN
9.6 Australia
9.7 Others
10 Latin America Gene Synthesis Market
10.1 Market Share by Country
10.2 Brazil
10.3 Argentina
10.4 Mexico
10.5 Others
11 Middle East and Africa Gene Synthesis Market
11.1 Market Share by Country
11.2 Saudi Arabia
11.3 United Arab Emirates
11.4 Nigeria
11.5 South Africa
11.6 Others
12 Regulatory Framework
12.1 Regulatory Overview
12.1.1 US FDA
12.1.2 EU EMA
12.1.3 INDIA CDSCO
12.1.4 JAPAN PMDA
12.1.5 Others
13 Patent Analysis
13.1 Analysis by Type of Patent
13.2 Analysis by Publication year
13.3 Analysis by Issuing Authority
13.4 Analysis by Patent Age
13.5 Analysis by CPC Analysis
13.6 Analysis by Patent Valuation
13.7 Analysis by Key Players
14 Grants Analysis
14.1 Analysis by year
14.2 Analysis by Amount Awarded
14.3 Analysis by Issuing Authority
14.4 Analysis by Grant Application
14.5 Analysis by Funding Institute
14.6 Analysis by NIH Departments
14.7 Analysis by Recipient Organization
15 Clinical Trials Analysis
15.1 Analysis by Trial Registration Year
15.2 Analysis by Trial Status
15.3 Analysis by Trial Phase
15.4 Analysis by Therapeutic Area
15.5 Analysis by Geography
16 Funding and Investment Analysis
16.1 Analysis by Funding Instances
16.2 Analysis by Type of Funding
16.3 Analysis by Funding Amount
16.4 Analysis by Leading Players
16.5 Analysis by Leading Investors
16.6 Analysis by Geography
17 Partnership and Collaborations Analysis
17.1 Analysis by Partnership Instances
17.2 Analysis by Type of Partnership
17.3 Analysis by Leading Players
17.4 Analysis by Geography
18 Supplier Landscape
18.1 ATDBio Ltd
18.1.1 Financial Analysis
18.1.2 Product Portfolio
18.1.3 Demographic Reach and Achievements
18.1.4 Mergers and Acquisitions
18.1.5 Certifications
18.2 General Biosystems
18.2.1 Financial Analysis
18.2.2 Product Portfolio
18.2.3 Demographic Reach and Achievements
18.2.4 Mergers and Acquisitions
18.2.5 Certifications
18.3 Macrogen CO.
18.3.1 Financial Analysis
18.3.2 Product Portfolio
18.3.3 Demographic Reach and Achievements
18.3.4 Mergers and Acquisitions
18.3.5 Certifications
18.4 Boster Biological Technology
18.4.1 Financial Analysis
18.4.2 Product Portfolio
18.4.3 Demographic Reach and Achievements
18.4.4 Mergers and Acquisitions
18.4.5 Certifications
18.5 Creative Biogene
18.5.1 Financial Analysis
18.5.2 Product Portfolio
18.5.3 Demographic Reach and Achievements
18.5.4 Mergers and Acquisitions
18.5.5 Certifications
18.6 Bioneer Pacific,
18.6.1 Financial Analysis
18.6.2 Product Portfolio
18.6.3 Demographic Reach and Achievements
18.6.4 Mergers and Acquisitions
18.6.5 Certifications
18.7 Exonbio
18.7.1 Financial Analysis
18.7.2 Product Portfolio
18.7.3 Demographic Reach and Achievements
18.7.4 Mergers and Acquisitions
18.7.5 Certifications
18.8 trenzyme GmbH
18.8.1 Financial Analysis
18.8.2 Product Portfolio
18.8.3 Demographic Reach and Achievements
18.8.4 Mergers and Acquisitions
18.8.5 Certifications
18.9 Twist Bioscience
18.9.1 Financial Analysis
18.9.2 Product Portfolio
18.9.3 Demographic Reach and Achievements
18.9.4 Mergers and Acquisitions
18.9.5 Certifications
18.10 BioCat GmbH
18.10.1 Financial Analysis
18.10.2 Product Portfolio
18.10.3 Demographic Reach and Achievements
18.10.4 Mergers and Acquisitions
18.10.5 Certifications
18.11 OriGene Technologies, Inc.
18.11.1 Financial Analysis
18.11.2 Product Portfolio
18.11.3 Demographic Reach and Achievements
18.11.4 Mergers and Acquisitions
18.11.5 Certifications
18.12 Integrated DNA Technologies
18.12.1 Financial Analysis
18.12.2 Product Portfolio
18.12.3 Demographic Reach and Achievements
18.12.4 Mergers and Acquisitions
18.12.5 Certifications
18.13 Eurofins Scientific
18.13.1 Financial Analysis
18.13.2 Product Portfolio
18.13.3 Demographic Reach and Achievements
18.13.4 Mergers and Acquisitions
18.13.5 Certifications
18.14 NZYTech
18.14.1 Financial Analysis
18.14.2 Product Portfolio
18.14.3 Demographic Reach and Achievements
18.14.4 Mergers and Acquisitions
18.14.5 Certifications
18.15 Genes and Enzymes
18.15.1 Financial Analysis
18.15.2 Product Portfolio
18.15.3 Demographic Reach and Achievements
18.15.4 Mergers and Acquisitions
18.15.5 Certifications
19 Key Opinion Leaders (KOL) Insights (Additional Insight)
20 Company Competitiveness Analysis (Additional Insight)
20.1 Very Small Companies
20.2 Small Companies
20.3 Mid-Sized Companies
20.4 Large Companies
20.5 Very Large Companies
21 Payment Methods (Additional Insight)
21.1 Government Funded
21.2 Private Insurance
21.3 Out-of-Pocket
*Additional insights provided are customisable as per client requirements.
The market attained a value of about USD 2.42 billion in 2023, driven by the rising prevalence of genetic disorders.
The global market size is anticipated to grow at a CAGR of 21.2% during the forecast period of 2024-2032 and reach a market value of USD 13.66 billion by 2032.
The rising investments from government and private sectors in the research and development activities is among several major factors that are aiding the market growth.
The increased focus on using gene synthesis for agricultural applications, such as the development of genetically modified crops globally is a major trend supporting the market growth.
The major regions of the market include North America, Europe, Asia Pacific, Latin America, Middle East and Africa. North America is currently leading the global market.
The components can be categorised into synthesizer, consumables, software and services.
The segments can be categorized into standard gene, express gene, and complex gene, among others.
Gene synthesis find wide applications in synthetic biology, genetic engineering, vaccine design, and therapeutics antibodies, among others.
The gene synthesis type can be categorized into gene library synthesis, solid phase synthesis, chip-based DNA synthesis, and PCR-based enzyme synthesis.
Key players involved in the market are ATDBio Ltd, General Biosystems, Macrogen CO., Boster Biological Technology, Creative Biogene, Bioneer Pacific, Exonbio, trenzyme GmbH, Twist Bioscience, BioCat GmbH, OriGene Technologies, Inc., Integrated DNA Technologies, Eurofins Scientific, NZYTech, and Genes and Enzymes.
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