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North America Protein Expression Market Size, Share, Growth: By Product: Expression Vectors, Competent Cells, Reagents, Instruments, Services; By Application: Industrial, Research, Therapeutic, Others; By System Type; Mammalian Cell Expression System, Others; By End User; Regional Analysis; Supplier Landscape; 2024-2032
North America Protein Expression Market Outlook
The North America protein expression market size was valued at USD 0.9 billion in 2023, driven by the increasing emphasis on developing effective therapeutics for treating chronic diseases in the region. The market is expected to grow at a CAGR of 8.23% during the forecast period of 2024-2032, with the values likely to rise from USD 1 billion in 2024 to USD 1.9 billion by 2032.
Key Takeaways
- 6 out of 10 Americans are affected by at least one chronic disease, according to the Centers for Disease Control and Prevention (CDC), which fuels the demand for protein-based therapeutics.
- Several key players are entering into strategic partnerships to create efficient protein expression systems. In July 2023, Ginkgo Bioworks announced the completion of the pilot phase of their partnership with Novo Nordisk A/S to develop novel expression systems for pharmaceutical products.
- Advancements in protein expression technologies are attracting major investments from various sectors. In July 2023, Toronto based Liberum Biotech Inc ., secured USD 1.8 million in seed funding for its platform called “protein synthesis as a service”.
North America Protein Expression Market Analysis
Protein expression involves the synthesis, modification, and regulation of proteins in living organisms. The study of protein expression can help to determine the best treatment as well as its effectiveness in a patient. For instance, understanding protein expression in cancer cells can provide information about the cancer subtype, the optimal treatment plan, and its efficacy. The rising interest in personalized medicine is likely to propel the North America protein expression market growth in the coming years.
The market is witnessing increased demand for protein-based therapeutics, which can be attributed to the rise in the burden of chronic diseases in North America. According to the Centers for Disease Control and Prevention (CDC), 6 out of 10 Americans are affected by at least one chronic disease. These chronic diseases, including cancer, diabetes, and heart disease, are the leading drivers of death and disability in the region and are also responsible for substantial healthcare expenditure. The rising prevalence of chronic diseases is expected to directly augment the market demand as proteins are utilized in both the study as well as the treatment of such conditions.
The North America protein expression market demand is driven by the growing pipeline of biological medicines such as monoclonal antibodies, gene therapies, and vaccines. This expansion in the biologics market fuels the need for robust protein expression systems that are both flexible and efficient. To manufacture such complex expression systems, several key players are entering into partnerships to share resources and expertise. In July 2023, Ginkgo Bioworks (a United States-based biotechnology company) announced the completion of the pilot phase of their partnership with Novo Nordisk A/S to develop novel expression systems for pharmaceutical products. Through collaborative efforts, the companies achieved their first milestone which included extensive modification and testing of a microbial expression system. The development of such engineered biological systems that can offer potential treatment options for patients with serious chronic diseases is anticipated to accelerate market growth.
One of the significant North America protein expression market trends is the increased advancements in protein expression technologies that allow scalable and cost-effective protein production and attract major investments from various sectors. In July 2023, Liberum Biotech Inc ., a Toronto-based startup, secured USD 1.8 million in seed funding for its platform “protein synthesis as a service” to support the development of its synthetic protein production technology. The company plans to use the funds to increase its production capacity and expand its portfolio of available proteins which also include the production of therapeutics and enzymes. The launch of innovative cell-free and cell-based platforms for protein synthesis is expected to bolster the market share in the forecast period.
North America Protein Expression Market Segmentation
The report offers a detailed analysis of the market based on the following segments:
| Market Breakup | Categories |
| Product | Expression Vectors, Competent Cells, Reagents, Instruments, Services |
| Application | Industrial, Research, Therapeutic, Others |
| System Type | Mammalian Cell Expression System, Yeast Cell Expression System, Insect Cell Expression System |
| End User | Academic Research, Contract Research Organizations, Pharmaceutical & Biotechnology Companies, Others |
| Country | United States, Canada |
North America Protein Expression Market: Competitor Landscape
The key features of the market report include patent analysis, grants analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:
- Thermo Fisher Scientific Inc.
- GenScript Biotech Corporation
- Agilent Technologies Inc.
- Danaher Corporation
- Bio-Rad Laboratories Inc.
- Promega Corporation
- New England Biolabs
- Becton, Dickinson and Company
- Merck KGaA
Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.
Key Highlights of the Report
| REPORT FEATURES | DETAILS |
| Base Year | 2023 |
| Historical Period | 2017-2023 |
| Forecast Period | 2024-2032 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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| Breakup by Product |
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| Breakup by Application |
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| Breakup by System Type |
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| Breakup by End User |
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| Breakup by Region |
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| Market Dynamics |
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| Supplier Landscape |
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| Companies Covered |
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*At Expert Market Research, we strive to always give you current and accurate information. The numbers depicted in the description are indicative and may differ from the actual numbers in the final EMR report.
1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage – Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 North America Protein Expression Market Overview
3.1 North America Protein Expression Market Historical Value (2017-2023)
3.2 North America Protein Expression Market Forecast Value (2024-2032)
4 North America Protein Expression Market Landscape*
4.1 North America Neonatal Ventilators: Developers Landscape
4.1.1 Analysis by Year of Establishment
4.1.2 Analysis by Company Size
4.1.3 Analysis by Region
4.2 North America Neonatal Ventilators: Product Landscape
4.2.1 Analysis by Product
4.2.2 Analysis by Application
5 North America Protein Expression Market Dynamics
5.1 Market Drivers and Constraints
5.2 SWOT Analysis
5.2.1 Strengths
5.2.2 Weaknesses
5.2.3 Opportunities
5.2.4 Threats
5.3 Porter’s Five Forces Model
5.3.1 Bargaining Power of Suppliers
5.3.2 Bargaining Power of Buyers
5.3.3 Threat of New Entrants
5.3.4 Threat of Substitutes
5.3.5 Degree of Rivalry
5.4 Key Demand Indicators
5.5 Key Price Indicators
5.6 Industry Events, Initiatives, and Trends
5.7 Value Chain Analysis
6 North America Protein Expression Market Segmentation (2017-2032)
6.1 North America Protein Expression Market (2017-2032) by Product
6.1.1 Market Overview
6.1.2 Expression Vectors
6.1.3 Competent Cells
6.1.4 Reagents
6.1.5 Instruments
6.1.6 Services
6.2 North America Protein Expression Market (2017-2032) by Application
6.2.1 Market Overview
6.2.2 Industrial
6.2.3 Research
6.2.4 Therapeutic
6.2.5 Others
6.3 North America Protein Expression Market (2017-2032) by System Type
6.3.1 Market Overview
6.3.2 Mammalian Cell Expression System
6.3.3 Yeast Cell Expression System
6.3.4 Insect Cell Expression System
6.4 North America Protein Expression Market (2017-2032) by End User
6.4.1 Market Overview
6.4.2 Academic Research
6.4.3 Contract Research Organizations
6.4.4 Pharmaceutical & Biotechnology Companies
6.4.5 Others
6.5 North America Protein Expression Market (2017-2032) by Country
6.5.1 Market Overview
6.5.2 United States
6.5.3 Canada
7 United States Protein Expression Market (2017-2032)
7.1 United States Protein Expression Market (2017-2032) by Product
7.1.1 Market Overview
7.1.2 Expression Vectors
7.1.3 Competent Cells
7.1.4 Reagents
7.1.5 Instruments
7.1.6 Services
7.2 United States Protein Expression Market (2017-2032) by Application
7.2.1 Market Overview
7.2.2 Industrial
7.2.3 Research
7.2.4 Therapeutic
7.2.5 Others
7.3 United States Protein Expression Market (2017-2032) by System Type
7.3.1 Market Overview
7.3.2 Mammalian Cell Expression System
7.3.3 Yeast Cell Expression System
7.3.4 Insect Cell Expression System
7.4 United States Protein Expression Market (2017-2032) by End User
7.4.1 Market Overview
7.4.2 Academic Research
7.4.3 Contract Research Organizations
7.4.4 Pharmaceutical & Biotechnology Companies
7.4.5 Others
8 Canada Protein Expression Market (2017-2032)
8.1 Canada Protein Expression Market (2017-2032) by Product
8.1.1 Market Overview
8.1.2 Expression Vectors
8.1.3 Competent Cells
8.1.4 Reagents
8.1.5 Instruments
8.1.6 Services
8.2 Canada Protein Expression Market (2017-2032) by Application
8.2.1 Market Overview
8.2.2 Industrial
8.2.3 Research
8.2.4 Therapeutic
8.2.5 Others
8.3 Canada Protein Expression Market (2017-2032) by System Type
8.3.1 Market Overview
8.3.2 Mammalian Cell Expression System
8.3.3 Yeast Cell Expression System
8.3.4 Insect Cell Expression System
8.4 Canada Protein Expression Market (2017-2032) by End User
8.4.1 Market Overview
8.4.2 Academic Research
8.4.3 Contract Research Organizations
8.4.4 Pharmaceutical & Biotechnology Companies
8.4.5 Others
9 Regulatory Framework
10 Patent Analysis
10.1 Analysis by Type of Patent
10.2 Analysis by Publication Year
10.3 Analysis by Issuing Authority
10.4 Analysis by Patent Age
10.5 Analysis by CPC Analysis
10.6 Analysis by Patent Valuation
10.7 Analysis by Key Players
11 Grants Analysis
11.1 Analysis by Year
11.2 Analysis by Amount Awarded
11.3 Analysis by Issuing Authority
11.4 Analysis by Grant Application
11.5 Analysis by Funding Institute
11.6 Analysis by Departments
11.7 Analysis by Recipient Organization
12 Funding and Investment Analysis
12.1 Analysis by Funding Instances
12.2 Analysis by Type of Funding
12.3 Analysis by Funding Amount
12.4 Analysis by Leading Players
12.5 Analysis by Leading Investors
12.6 Analysis by Geography
13 Partnership and Collaborations Analysis
13.1 Analysis by Partnership Instances
13.2 Analysis by Type of Partnership
13.3 Analysis by Leading Players
13.4 Analysis by Geography
14 Supplier Landscape
14.1 Market Share by Top 5 Companies
14.2 Thermo Fisher Scientific Inc.
14.2.1 Financial Analysis
14.2.2 Product Portfolio
14.2.3 Demographic Reach and Achievements
14.2.4 Mergers and Acquisitions
14.2.5 Certifications
14.3 GenScript Biotech Corporation
14.3.1 Financial Analysis
14.3.2 Product Portfolio
14.3.3 Demographic Reach and Achievements
14.3.4 Mergers and Acquisitions
14.3.5 Certifications
14.4 Agilent Technologies Inc.
14.4.1 Financial Analysis
14.4.2 Product Portfolio
14.4.3 Demographic Reach and Achievements
14.4.4 Mergers and Acquisitions
14.4.5 Certifications
14.5 Danaher Corporation
14.5.1 Financial Analysis
14.5.2 Product Portfolio
14.5.3 Demographic Reach and Achievements
14.5.4 Mergers and Acquisitions
14.5.5 Certifications
14.6 Bio-Rad Laboratories Inc.
14.6.1 Financial Analysis
14.6.2 Product Portfolio
14.6.3 Demographic Reach and Achievements
14.6.4 Mergers and Acquisitions
14.6.5 Certifications
14.7 Promega Corporation
14.7.1 Financial Analysis
14.7.2 Product Portfolio
14.7.3 Demographic Reach and Achievements
14.7.4 Mergers and Acquisitions
14.7.5 Certifications
14.8 New England Biolabs
14.8.1 Financial Analysis
14.8.2 Product Portfolio
14.8.3 Demographic Reach and Achievements
14.8.4 Mergers and Acquisitions
14.8.5 Certifications
14.9 Becton, Dickinson and Company
14.9.1 Financial Analysis
14.9.2 Product Portfolio
14.9.3 Demographic Reach and Achievements
14.9.4 Mergers and Acquisitions
14.9.5 Certifications
14.10 Merck KGaA
14.10.1 Financial Analysis
14.10.2 Product Portfolio
14.10.3 Demographic Reach and Achievements
14.10.4 Mergers and Acquisitions
14.10.5 Certifications
15 North America Protein Expression Market – Distribution Model (Additional Insight)
15.1 Overview
15.2 Potential Distributors
15.3 Key Parameters for Distribution Partner Assessment
16 Key Opinion Leaders (KOL) Insights (Additional Insight)
17 Company Competitiveness Analysis (Additional Insight)
17.1 Very Small Companies
17.2 Small Companies
17.3 Mid-Sized Companies
17.4 Large Companies
17.5 Very Large Companies
18 Payment Methods (Additional Insight)
18.1 Government Funded
18.2 Private Insurance
18.3 Out-of-Pocket
*Additional insights provided are customisable as per client requirements.
* The coverage of the Market Landscape section depends on the data availability and may cover a minimum of 80% of the total market. The EMR team strives to make this section as comprehensive as possible.
Key Questions Answered in the Report
The market attained a value of about USD 0.9 billion in 2023 driven by the advancements in protein expression technologies in the region.
The market is anticipated to grow at a CAGR of 8.23% during the forecast period of 2024-2032, likely to reach a market value of USD 1.9 billion by 2032.
The growing prevalence of chronic diseases and the rising healthcare expenditure are fuelling the demand for the market.
One of the significant trends in the market is the increased strategic collaborations amongst the prominent market players. In July 2023, Ginkgo Bioworks (a United States-based biotechnology company) announced the completion of the pilot phase of their partnership with Novo Nordisk A/S to develop novel expression systems for pharmaceutical products.
Based on the product, the market is segmented into expression vectors, competent cells, reagents, instruments, and services.
Major applications of the market are industrial, research, and therapeutics among others.
By system type, the market is divided into mammalian cell expression system, yeast cell expression system, insect cell expression system.
End users of the market are academic research, contract research organizations, and pharmaceutical and biotechnology companies among others.
The market segmentation by countries includes the United States of America and Canada.
The key players in the market are Thermo Fisher Scientific Inc., GenScript Biotech Corporation, Agilent Technologies Inc., Danaher Corporation, Bio-Rad Laboratories Inc., Promega Corporation, New England Biolabs, Becton, Dickinson and Company, and Merck KGaA.
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